Cited by 546Smoking Behavior and CessationSubstance Abuse Treatment and OutcomesInhalation and Respiratory Drug Delivery

Electronic cigarettes: review of use, content, safety, effects on smokers and potential for harm and benefit

Open access
Hajek, Peter, Etter, Jean‐François, Benowitz, Neal, Eissenberg, Thomas, McRobbie, Hayden·2014·Addiction

Abstract

Aims: We reviewed available research on the use, content and safety of electronic cigarettes ( EC ), and on their effects on users, to assess their potential for harm or benefit and to extract evidence that can guide future policy. Methods: Studies were identified by systematic database searches and screening references to F ebruary 2014. Results: EC aerosol can contain some of the toxicants present in tobacco smoke, but at levels which are much lower. Long‐term health effects of EC use are unknown but compared with cigarettes, EC are likely to be much less, if at all, harmful to users or bystanders. EC are increasingly popular among smokers, but to date there is no evidence of regular use by never‐smokers or by non‐smoking children. EC enable some users to reduce or quit smoking. Conclusions: Allowing EC to compete with cigarettes in the market‐place might decrease smoking‐related morbidity and mortality. Regulating EC as strictly as cigarettes, or even more strictly as some regulators propose, is not warranted on current evidence. Health professionals may consider advising smokers unable or unwilling to quit through other routes to switch to EC as a safer alternative to smoking and a possible pathway to complete cessation of nicotine use.

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    “Vaping has the advantage that it does not involve tobacco combustion, which is the primary source of harm from smoking cigarettes [7, 17].”

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Authors
Hajek, P., Etter, J., Benowitz, N., Eissenberg, T., & McRobbie, H.
Affiliations
  • UK Centre for Tobacco and Alcohol Studies Wolfson Institute of Preventive Medicine Queen Mary University of London London UK
  • University of Geneva (CH)
  • University of California, San Francisco (US)
  • Virginia Commonwealth University (US)
  • Queen Mary University of London (GB)
Corresponding author
McRobbie, Hayden
Venue
Addiction
Publisher
Wiley
Published
2014-07-31
Volume
109
Issue
11
Pages
1801-1810
ISSN
  • 0965-2140 (ISSN-L)
  • 1360-0443
OpenAlex
W2121853742
Cited by
546
References
100
Citations by year
2026: 13 · 2025: 19 · 2024: 20 · 2023: 26 · 2022: 29 · 2021: 34 · 2020: 48 · 2019: 53 · 2018: 60 · 2017: 59 · 2016: 66 · 2015: 98 · 2014: 19 · 2012: 1
FWCI
9.48
Type
journal article
Language
en
Open access
Locations
  • Addiction (publishedVersion)
  • PubMed (publishedVersion)
  • Archive ouverte UNIGE (University of Geneva) (publishedVersion, other-oa)
  • PubMed Central (acceptedVersion)
  • eScholarship (California Digital Library) (submittedVersion, cc-by-nc-sa)
  • Archive ouverte UNIGE (University of Geneva) (submittedVersion, cc-by)
Funders
  • National Institutes of Health
  • Medical Research Council (MR/K023195/1)
  • Economic and Social Research Council (ES/G007489/1)
  • National Institute on Drug Abuse (R01-DA 02277, R01DA002277, P50DA036105)
  • National Cancer Institute (P50CA180890)
  • Center for Tobacco Products (P50DA036105, P50CA180890)
Topics
  • Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Inhalation and Respiratory Drug Delivery
Keywords
electronic cigarettes, e-cigarette aerosol, harm reduction, smoking cessation, never smokers, children, e-cigarette regulation, health policy, nicotine use
MeSH terms
Smoking Prevention, Humans, Nicotine, Safety, Risk Assessment, Electronic Nicotine Delivery Systems

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