Cited by 54Probiotics and Fermented FoodsDermatology and Skin DiseasesFood Allergy and Anaphylaxis Research

Systematic review and meta-analysis on the use of probiotic supplementation in pregnant mother, breastfeeding mother and infant for the prevention of atopic dermatitis in children

Amalia, Nasya, Orchard, David, Francis, Kate Louise, King, Emma·2020·Australasian Journal of Dermatology

Abstract

Probiotic supplementation may decrease the risk of allergic disease; however, there are differences between studies, such as the type of probiotic, the route or the duration of supplementation. Therefore, determining the most effective probiotic strain/s, route of administration and duration for clinical recommendation has been difficult. An electronic systematic literature search was undertaken between using Ovid MEDLINE, Embase, PubMed and Cochrane. Risk ratio (RR) and 95% confidence interval (CI) are presented for the studies. PEDro scale and Newcastle-Ottawa Scale were used to assess the quality of the included studies. A total of 21 studies met the inclusion criteria. Strain-specific sub-meta-analyses indicated that single strains are not as effective as probiotic mixtures and administration to a combination of pregnant mothers, breastfeeding mothers and infants had a reduced risk in the onset of atopic dermatitis in children. Our systematic review and meta-analysis showed that a mixture of probiotic supplementation given to the mother in pregnancy and continuing while breastfeeding and also to the infant in children classified as high-risk for atopic dermatitis and non-high-risk groups is the most efficacious in reducing the risk of incidence of atopic dermatitis in children.

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Registry

Crossref · 10.1111/ajd.13186

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45 of 45 references verified0 citation errors · 0 not checkable

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  • Only some strains of Lactobacillus spp., Bifidobacterium spp., and Propionibacterium spp. showed beneficial results in reducing the risk of atopic eczema in children, while other strains of the same species did not.

    “Following these studies, it was mentioned that only some strains of Lactobacillus spp., Bifidobacterium spp., and Propionibacterium spp. showed beneficial results, while other strains of the same species did not.”

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Authors
Amalia, N., Orchard, D., Francis, K. L., & King, E.
Affiliations
  • The University of Melbourne (AU)
  • Royal Children's Hospital (AU)
Corresponding author
King, Emma
Venue
Australasian Journal of Dermatology
Publisher
Wiley
Published
2019-11-12
Volume
61
Issue
2
Pages
e158-e173
ISSN
  • 0004-8380 (ISSN-L)
  • 1440-0960
OpenAlex
W2986768741
Cited by
54
References
45
Citations by year
2026: 7 · 2025: 6 · 2024: 8 · 2023: 14 · 2022: 10 · 2021: 7 · 2020: 2
FWCI
0.43
Type
journal article
Language
en
Open access
closed
Locations
  • Australasian Journal of Dermatology (publishedVersion)
  • PubMed (publishedVersion)
  • Minerva Access (University of Melbourne) (submittedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Health Sciences › Medicine › Dermatology › Dermatology and Skin Diseases
  • Health Sciences › Medicine › Immunology and Allergy › Food Allergy and Anaphylaxis Research
Keywords
probiotics, atopic dermatitis, children, pregnancy, breastfeeding, infant supplementation, probiotic combination, single-strain probiotics, high-risk infants, allergy prevention, route of administration, duration of supplementation
MeSH terms
Breast Feeding, Child, Dermatitis, Atopic, Eczema, Female, Humans, Hypersensitivity, Immediate, Infant, Pregnancy, Prenatal Care, Primary Prevention, Probiotics, Rhinitis, Allergic

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