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Successful recovery of COVID-19 pneumonia in a renal transplant recipient with long-term immunosuppression
Open accessAbstract
The current outbreak of Coronavirus Disease 2019 (COVID-19) has raised great concern worldwide, but its impact on transplant recipients is unknown. We report here the clinical features and therapeutic course of the first reported renal transplant recipient with confirmed COVID-19 pneumonia. This is a 52-year-old man who received kidney transplantation 12 years ago. His overall clinical characteristics (symptoms, laboratory examinations, and chest CT) were similar to those of non-transplanted COVID-19 patients. Following a treatment regimen consisting of reduced immunosuppressant use and low dose methylprednisolone-based therapy, the COVID-19 pneumonia in this long-term immunosuppressive patient was successfully recovered. This effectively treated case has reference value for the future treatment of other transplant patients with COVID-19 pneumonia.
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Chen, N., Zhou, M., Dong, X., Qu, J., Gong, F., Han, Y., Qiu, Y., Wang, J., Liu, Y., Wei, Y., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30211-7 · Cited by 21,415
First case of 2019 novel coronavirus in the United States
Holshue, M. L., DeBolt, C., Lindquist, S., Lofy, K. H., Wiesman, J., Bruce, H., Spitters, C., Ericson, K., Wilkerson, S., Tural, A., et al. (2020) · New England Journal of Medicine · doi:10.1056/nejmoa2001191 · Cited by 6,030
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Avanzato, V. A., Matson, M. J., Seifert, S. N., Pryce, R., Williamson, B. N., Anzick, S. L., Barbian, K., Judson, S. D., Fischer, E. R., Martens, C., et al. (2020) · Cell · doi:10.1016/j.cell.2020.10.049 · Cited by 716
Elens, L., Langman, L. J., Hesselink, D. A., Bergan, S., Moes, D. J. A. R., Molinaro, M., Venkataramanan, R., & Lemaitre, F. (2020) · Therapeutic Drug Monitoring · doi:10.1097/ftd.0000000000000761 · Cited by 677
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Boettler, T., Newsome, P. N., Mondelli, M. U., Maticic, M., Cordero, E., Cornberg, M., & Berg, T. (2020) · JHEP Reports · doi:10.1016/j.jhepr.2020.100113 · Cited by 477
Current pharmacological treatments for COVID‐19: What's next?
Scavone, C., Brusco, S., Bertini, M., Sportiello, L., Rafaniello, C., Zoccoli, A., Berrino, L., Racagni, G., Rossi, F., & Capuano, A. (2020) · British Journal of Pharmacology · doi:10.1111/bph.15072 · Cited by 283
Metadata
- Authors
- Zhu, L., Xu, X., Ma, K., Yang, J., Guan, H., Chen, S., Chen, Z., & Chen, G.
- Venue
- American Journal of Transplantation
- Publisher
- Elsevier BV
- Published
- 2020-07
- Volume
- 20
- Issue
- 7
- Pages
- 1859-1863
- ISSN
- 1600-6135 (ISSN-L)
- OpenAlex
- W3011172073
- Cited by
- 333
- References
- 2
- FWCI
- 9.45
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- Zhu, L., Xu, X., Ma, K., Yang, J., Guan, H., Chen, S., Chen, Z., & Chen, G. (2020). Successful recovery of COVID-19 pneumonia in a renal transplant recipient with long-term immunosuppression. American Journal of Transplantation. https://doi.org/10.1111/ajt.15869
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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