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Cited by 283

The DOI matches its Crossref record; 87 of the 87 references it cites were found in a registry or an index.

Current pharmacological treatments for COVID‐19: What's next?

Open access
Scavone, Cristina, Brusco, Simona, Bertini, Michele, Sportiello, Liberata, Rafaniello, Concetta, Zoccoli, Alice, Berrino, Liberato, Racagni, Giorgio, Rossi, Francesco, Capuano, Annalisa·2020·British Journal of Pharmacology

Abstract

Since December 2019 SARS‐Cov‐2 was found responsible for the disease COVID‐19, which has spread worldwide. No specific therapies/vaccines are yet available for the treatment of COVID‐19. Drug repositioning may offer a strategy and a number of drugs have been repurposed, including lopinavir/ritonavir, remdesivir, favipiravir and tocilizumab. This paper describes the main pharmacological properties of such drugs administered to patients with COVID‐19, focusing on their antiviral, immune‐modulatory and/or anti‐inflammatory actions. Where available, data from clinical trials involving patients with COVID‐19 are reported. Preliminary clinical trials seem to support their benefit. However, such drugs in COVID‐19 patients have peculiar safety profiles. Thus, adequate clinical trials are necessary for these compounds. Nevertheless, while waiting for effective preventive measures i.e. vaccines, many clinical trials on drugs belonging to different therapeutic classes are currently underway. Their results will help us in defining the best way to treat COVID‐19 and reducing its symptoms and complications. Linked Articles: This article is part of a themed issue on The Pharmacology of COVID‐19. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v177.21/issuetoc

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Registry

Crossref · 10.1111/bph.15072

Cites

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Metadata

Authors
Scavone, C., Brusco, S., Bertini, M., Sportiello, L., Rafaniello, C., Zoccoli, A., Berrino, L., Racagni, G., Rossi, F., & Capuano, A.
Venue
British Journal of Pharmacology
Publisher
Wiley
Published
2020-05-15
Volume
177
Issue
21
Pages
4813-4824
ISSN
  • 0007-1188 (ISSN-L)
  • 1476-5381
OpenAlex
W3019596330
Cited by
283
References
87
FWCI
7.79
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Current pharmacological treatments for COVID‐19: What's next? https://app.cochat.ai/papers/10.1111/bph.15072
The paper
Scavone, C., Brusco, S., Bertini, M., Sportiello, L., Rafaniello, C., Zoccoli, A., Berrino, L., Racagni, G., Rossi, F., & Capuano, A. (2020). Current pharmacological treatments for COVID‐19: What's next? British Journal of Pharmacology. https://doi.org/10.1111/bph.15072

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.