Somatotropic-Testicular Axis: A Crosstalk Between GH/IGF-I and Gonadal Hormones During Development, Transition, and Adult Age

Insulin and insulin-like growth factor signalling in neoplasia

Pollak, M. (2008) · Nature Reviews Cancer · doi:10.1038/nrc2536 · Cited by 2,059 · see citing works

Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis

Renehan, A. G., Zwahlen, M., Minder, C., O'Dwyer, S. T., Shalet, S. M., & Egger, M. (2004) · The Lancet · doi:10.1016/s0140-6736(04)16044-3 · Cited by 1,697 · see citing works

Sex‐hormone binding-globulin

ANDERSON, D. C. (1974) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1974.tb03298.x · Cited by 1,127 · see citing works

Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

Udy, G. B., Towers, R. P., Snell, R. G., Wilkins, R. J., Park, S.-H., Ram, P. A., Waxman, D. J., & Davey, H. W. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.14.7239 · Cited by 986 · see citing works

Genetics of male infertility

Krausz, C. G., & Riera‐Escamilla, A. (2018) · Nature Reviews Urology · doi:10.1038/s41585-018-0003-3 · Cited by 953 · see citing works

A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)

Zhou, Y., Xu, B. C., Maheshwari, H., He, L., Reed, M. A., Lozykowski, M. G., Okada, S., Cataldo, L. R., Coschigamo, K., Wagner, T. E., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.24.13215 · Cited by 802 · see citing works

Serum insulin-like growth factor-I in 1030 healthy children, adolescents, and adults: relation to age, sex, stage of puberty, testicular size, and body mass index

Juul, A., Bang, P., Hertel, N. T., Main, K., Dalgaard, P., Jørgensen, K., Müller, J., Hall, K. E., & Skakkebaek, N. E. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.78.3.744 · Cited by 773 · see citing works

Guidelines for Growth Hormone and Insulin-Like Growth Factor-I Treatment in Children and Adolescents: Growth Hormone Deficiency, Idiopathic Short Stature, and Primary Insulin-Like Growth Factor-I Deficiency

Grimberg, A., DiVall, S. A., Polychronakos, C., Allen, D. B., Cohen, L. E., Quintos, J. B., Rossi, W. C., Feudtner, C., & Murad, M. H. (2016) · Hormone Research in Paediatrics · doi:10.1159/000452150 · Cited by 719 · see citing works

Physical growth of Swiss children from birth to 20 years of age. First Zurich longitudinal study of growth and development.

Prader, A., Largo, R. H., Molinari, L., & Issler, C. (1989) · PubMed · Cited by 677 · see citing works

Effects of an Igf1 Gene Null Mutation on Mouse Reproduction

Baker, J., Hardy, M. P., Zhou, J., Bondy, C., Lupu, F., Bellvé, A. R., & Efstratiadis, A. (1996) · Molecular Endocrinology · doi:10.1210/mend.10.7.8813730 · Cited by 674 · see citing works

Leptin and Androgens in Male Obesity: Evidence for Leptin Contribution to Reduced Androgen Levels

Isidori, A. M., Caprio, M., Strollo, F., Moretti, C., Frajese, G., Isidori, A., & Fabbri, A. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.10.6082 · Cited by 560 · see citing works

Growth Hormone Insensitivity Associated with a STAT5b Mutation

Kofoed, E. M., Hwa, V., Little, B. M., Woods, K. A., Buckway, C. K., Tsubaki, J., Pratt, K. L., Bezrodnik, L., Jasper, H., Tepper, A., et al. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa022926 · Cited by 522 · see citing works

Growth Hormone (GH) Insensitivity Due to Primary GH Receptor Deficiency

Rosenfeld, R. G., Rosenbloom, A. L., & Guevara‐Aguirre, J. (1994) · Endocrine Reviews · doi:10.1210/edrv-15-3-369 · Cited by 482 · see citing works

The role of the insulin-like growth factors in the central nervous system

D’Ercole, A. J., Ye, P., Calikoglu, A. S., & Gutierrez-Ospina, G. (1996) · Molecular Neurobiology · doi:10.1007/bf02740625 · Cited by 447 · see citing works

Differential impact of age, sex steroid hormones, and obesity on basal versus pulsatile growth hormone secretion in men as assessed in an ultrasensitive chemiluminescence assay

Veldhuis, J. D., Liem, A. Y., South, S. A., WELTMAN, A. L., Weltman, J. Y., Clemmons, D., Abbott, R. D., Mulligan, T., Johnson, M. L., & Pincus, S. M. (1995) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.80.11.7593428 · Cited by 385 · see citing works

Diagnosis, Genetics, and Therapy of Short Stature in Children: A Growth Hormone Research Society International Perspective

Collett‐Solberg, P. F., Ambler, G. R., Backeljauw, P. F., Bidlingmaier, M., Biller, B. M. K., Boguszewski, M. C. D. S., Cheung, P. T., Choong, C. S., Cohen, L. E., Cohen, P., et al. (2019) · Hormone Research in Paediatrics · doi:10.1159/000502231 · Cited by 370 · see citing works

Serum insulin‐like growth factor I in a random population sample of men and women: relation to age, sex, smoking habits, coffee consumption and physical activity, blood pressure and concentrations of plasma lipids, fibrinogen, parathyroid hormone and osteocalcin

Landin‐Wllhelmsen, K., Wllhelmsen, L., Lappast, G., Rosén, T., Lindstedt, G., Lundberg, P., & Bengtsson, B. (1994) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1994.tb02556.x · Cited by 340 · see citing works

Laron Dwarfism and Mutations of the Growth Hormone–Receptor Gene

Amselem, S., Duquesnoy, P., Attree, O., et al. (1989) · New England Journal of Medicine · doi:10.1056/nejm198910123211501 · Cited by 318 · see citing works

Homozygous and Heterozygous Expression of a Novel Insulin-Like Growth Factor-I Mutation

Walenkamp, M. J. E., Karperien, M., Pereira, A. M., Hilhorst‐Hofstee, Y., van Doorn, J., Chen, J. W., Mohan, S., Denley, A., Forbes, B. E., van Duyvenvoorde, H. A., et al. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1254 · Cited by 314 · see citing works

Leptin in reproduction

Caprio, M., Fabbrini, E., Isidori, A. M., Aversa, A., & Fabbri, A. (2001) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(00)00352-0 · Cited by 308 · see citing works

Growth Hormone (GH)-Deficient Men Are More Responsive to GH Replacement Therapy Than Women1

Burman, P., Johansson, A. G., Siegbahn, A., Vessby, B. O., & Karlsson, F. A. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.2.3776 · Cited by 307 · see citing works

Gonadal Peptides as Mediators of Development and Functional Control of the Testis: An Integrated System with Hormones and Local Environment

Gnessi, L., Fabbri, A., & Spera, G. (1997) · Endocrine Reviews · doi:10.1210/edrv.18.4.0310 · Cited by 305 · see citing works

Spontaneous Growth Hormone Secretion Increases during Puberty in Normal Girls and Boys*

Rose, S. R., Municchi, G., Barnes, K. M., Kamp, G. A., Uriarte, M., ROSS, J. L., CASSORLA, F. G., & Cutler, G. B. (1991) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-73-2-428 · Cited by 293 · see citing works

Serum insulin-like growth factor-I in 1030 healthy children, adolescents, and adults: relation to age, sex, stage of puberty, testicular size, and body mass index.

Juul, A., Bang, P., Hertel, N. T., et al. (1994) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.78.3.8126152 · Cited by 272 · see citing works

Expression of Functional Leptin Receptors in Rodent Leydig Cells1

Caprio, M., Isidori, A. M., Carta, A. R., Moretti, C., Dufau, M. L., & Fabbri, A. (1999) · Endocrinology · doi:10.1210/endo.140.11.7088 · Cited by 270 · see citing works

Endogenous growth hormone secretion and clearance rates in normal boys, as determined by deconvolution analysis: relationship to age, pubertal status, and body mass.

Martha, P. M., Gorman, K. M., Blizzard, R. M., Rogol, A. D., & Veldhuis, J. D. (1992) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.74.2.1730812 · Cited by 268 · see citing works

Regulation of Growth Hormone and Somatomedin-C Secretion in Postmenopausal Women: Effect of Physiological Estrogen Replacement*

Dawson‐Hughes, B., STERN, D., GOLDMAN, J., & Reichlin, S. (1986) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-63-2-424 · Cited by 250 · see citing works

An Essential Role for Insulin and IGF1 Receptors in Regulating Sertoli Cell Proliferation, Testis Size, and FSH Action in Mice

Pitetti, J.-L., Calvel, P., Zimmermann, C., Conne, B., Papaioannou, M. D., Aubry, F., Cederroth, C. R., Urner, F., Fumel, B., Crausaz, M., et al. (2013) · Molecular Endocrinology · doi:10.1210/me.2012-1258 · Cited by 240 · see citing works

Deficiency of the Circulating Insulin-like Growth Factor System Associated with Inactivation of the Acid-Labile Subunit Gene

Domené, H. M., Bengolea, S. V., Martínez, A. S., Ropelato, M. G., Pennisi, P. A., Scaglia, P. A., Heinrich, J. J., & Jasper, H. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa013100 · Cited by 239 · see citing works

Regulatory mechanisms of growth hormone secretion are sexually dimorphic.

Jaffe, C. A., Ocampo-Lim, B., Guo, W., Krueger, K., Sugahara, I., DeMott-Friberg, R., Bermann, M., & Barkan, A. L. (1998) · Journal of Clinical Investigation · doi:10.1172/jci2908 · Cited by 236 · see citing works

Estrogen and Testosterone, But Not a Nonaromatizable Androgen, Direct Network Integration of the Hypothalamo-Somatotrope (Growth Hormone)-Insulin-Like Growth Factor I Axis in the Human: Evidence from Pubertal Pathophysiology and Sex-Steroid Hormone Replacement1

Veldhuis, J. D., Metzger, D. L., MARTHA, P. M., Mauras, N., Kerrigan, J. R., Keenan, B. S., Rogol, A. D., & Pincus, S. M. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.10.4317 · Cited by 225 · see citing works

Estrogen inhibits GH signaling by suppressing GH-induced JAK2 phosphorylation, an effect mediated by SOCS-2

Leung, K. C., Doyle, N., Ballesteros, M., Sjogren, K., Watts, C. K. W., Low, T. H., Leong, G. M., Ross, R. J. M., & Ho, K. K. Y. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0337600100 · Cited by 218 · see citing works

Expanding the Mind: Insulin-Like Growth Factor I and Brain Development

D’Ercole, A. J., & Ye, P. (2008) · Endocrinology · doi:10.1210/en.2008-0920 · Cited by 208 · see citing works

Growth Hormone (GH)-Deficient Men Are More Responsive to GH Replacement Therapy Than Women

Burman, P. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.82.2.550 · Cited by 201 · see citing works

Paternally InheritedIGF2Mutation and Growth Restriction

Begemann, M., Zirn, B., Santen, G. W. E., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1415227 · Cited by 200 · see citing works

Clinical review 75: Recent advances in pathogenesis, diagnosis, and management of acromegaly

Melmed, S. K., Ho, K. K. Y., Klibanski, A., Reichlin, S., & Thorner, M. O. (1995) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.80.12.8530571 · Cited by 194 · see citing works

The Actions of Insulin-Like Growth Factors I and II on Cultured Sertoli Cells*

BORLAND, K. M., Mita, M., Oppenheimer, C., et al. (1984) · Endocrinology · doi:10.1210/endo-114-1-240 · Cited by 194 · see citing works

Final height and pubertal development in 55 children with idiopathic growth hormone deficiency, treated for between 2 and 15 years with human growth hormone

Burns, E. C., Tanner, J. M., Preece, M. A., & Cameron, N. (1981) · European Journal of Pediatrics · doi:10.1007/bf00441309 · Cited by 191 · see citing works

The Effect of Androgens on the Pulsatile Release and the Twenty-Four-Hour Mean Concentration of Growth Hormone in Peripubertal Males*

Link, K., Blizzard, R. M., Evans, W. S., Kaiser, D. L., Parker, M. W., & Rogol, A. D. (1986) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-62-1-159 · Cited by 182 · see citing works

Immunoreactive sites and accumulation of somatomedin-C in rat Sertoli-spermatogenic cell co-cultures

Tres, L. L., Smith, E. P., Wyk, J. J. V., & Kierszenbaum, A. L. (1986) · Experimental Cell Research · doi:10.1016/0014-4827(86)90424-6 · Cited by 179 · see citing works

Divergent roles of growth factors in the GnRH regulation of puberty in mice

DiVall, S. A., Williams, T. R., Carver, S. E., Koch, L., Brüning, J. C., Kahn, C. R., Wondisford, F. E., Radovick, S., & Wolfe, A. (2010) · Journal of Clinical Investigation · doi:10.1172/jci41069 · Cited by 176 · see citing works

The Consequences of Altered Somatotropic System on Reproduction1

Chandrashekar, V., Zaczek, D., & Bartke, A. (2004) · Biology of Reproduction · doi:10.1095/biolreprod.103.027060 · Cited by 175 · see citing works

Pituitary and Testicular Function in Growth Hormone Receptor Gene Knockout Mice

Chandrashekar, V., Bartke, A., Coschigano, K. T., & Kopchick, J. J. (1999) · Endocrinology · doi:10.1210/endo.140.3.6557 · Cited by 163 · see citing works

Free Insulin-Like Growth Factor I Serum Levels in 1430 Healthy Children and Adults, and Its Diagnostic Value in Patients Suspected of Growth Hormone Deficiency1

Juul, A., Holm, K., Kastrup, K. W., Pedersen, S. A., Michaelsen, K. F., Scheike, T., Rasmussen, S. B., Müller, J., & Skakkebæk, N. E. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.82.8.4137 · Cited by 161 · see citing works

Independent control of the production of insulin-like growth factor I and its binding protein by cultured testicular cells

Ćailleau, J., Vermeire, S., & Verhoeven, G. (1990) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(90)90091-l · Cited by 155 · see citing works

Cancer Incidence in Patients With Acromegaly: A Cohort Study and Meta-Analysis of the Literature

Dal, J., Leisner, M. Z., Hermansen, K., et al. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-02457 · Cited by 150 · see citing works

Cellular Location and Hormonal Regulation of Ghrelin Expression in Rat Testis1

Barreiro, M. L., Gaytán, F., Caminos, J. E., Pinilla, L., Casanueva, F. F., Aguilar, E., Diéguez, C., & Tena‐Sempere, M. (2002) · Biology of Reproduction · doi:10.1095/biolreprod.102.006965 · Cited by 143 · see citing works

Insulin and IGF1 Receptors Are Essential for XX and XY Gonadal Differentiation and Adrenal Development in Mice

Pitetti, J.-L., Calvel, P., Romero, Y., Conne, B., Truong, V., Papaioannou, M. D., Schaad, O., Docquier, M., Herrera, P. L., Wilhelm, D., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003160 · Cited by 141 · see citing works

MECHANISMS IN ENDOCRINOLOGY: Estradiol as a male hormone

Russell, N., & Grossmann, M. (2019) · European Journal of Endocrinology · doi:10.1530/eje-18-1000 · Cited by 138 · see citing works

Growth hormone secretory profiles in conscious female rats

CLARK, R. G., Carlsson, L. M. S., & Robinson, I. C. A. F. (1987) · Journal of Endocrinology · doi:10.1677/joe.0.1140399 · Cited by 137 · see citing works

Growth Hormone Pulsatility and the Endocrine Milieu during Sexual Maturation in Male and Female Rats

Gabriel, S. M., Roncancio, J. R., & Ruiz, N. S. (2008) · Neuroendocrinology · doi:10.1159/000126284 · Cited by 135 · see citing works

Insulin-like growth factor-1 (IGF-I) and IGF-I receptor in human testis: an immunohistochemical study

Vannelli, B., Barni, T., Orlando, C., Natali, A., Serio, M., & Balboni, G. (1988) · Fertility and Sterility · doi:10.1016/s0015-0282(16)59837-9 · Cited by 134 · see citing works

Estrogen and Testosterone, But Not a Nonaromatizable Androgen, Direct Network Integration of the Hypothalamo-Somatotrope (Growth Hormone)-Insulin-Like Growth Factor I Axis in the Human: Evidence from Pubertal Pathophysiology and Sex-Steroid Hormone Replacement

Veldhuis, J. D. (1997) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.82.10.3414 · Cited by 132 · see citing works

Consequences of growth hormone (GH) overexpression and GH resistance

Bartke, A., Chandrashekar, V., Bailey, B., Zaczek, D., & Turyn, D. (2002) · Neuropeptides · doi:10.1054/npep.2002.0889 · Cited by 130 · see citing works

Increased hGH production rate after low-dose estrogen therapy in prepubertal girls with Turner’s syndrome.

Mauras, N., Rogol, A. D., & Veldhuis, J. D. (1990) · Pediatric Research · doi:10.1203/00006450-199012000-00018 · Cited by 127 · see citing works

Growth curves for Laron syndrome.

Laron, Z., Lilos, P., & Klinger, B. (1993) · Archives of Disease in Childhood · doi:10.1136/adc.68.6.768 · Cited by 123 · see citing works

Insulin, insulin-like growth factor I (IGF-I) and IGF-II enhance basal and gonadotrophin-releasing hormone-stimulated luteinizing hormone release from rat anterior pituitary cells in vitro

Soldani, R., Cagnacci, A., & Yen, S. S. C. (1994) · European Journal of Endocrinology · doi:10.1530/eje.0.1310641 · Cited by 122 · see citing works

Gender Differences in the Effects of Long Term Growth Hormone (GH) Treatment on Bone in Adults with GH Deficiency1

Johansson, A. G., Engström, B. E., Ljunghall, S., Karlsson, F. A., & Burman, P. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.6.5743 · Cited by 118 · see citing works

Sexual Dimorphism of Somatostatin and Growth Hormone-Releasing Factor Signaling in the Control of Pulsatile Growth Hormone Secretion in the Rat*

PAINSON, J.-C., & Tannenbaum, G. S. (1991) · Endocrinology · doi:10.1210/endo-128-6-2858 · Cited by 117 · see citing works

Delayed Puberty but Normal Fertility in Mice With Selective Deletion of Insulin Receptors From Kiss1 Cells

Qiu, X., Dowling, A. R., Marino, J. S., Faulkner, L. D., Bryant, B., Brüning, J. C., Elias, C. F., & Hill, J. W. (2013) · Endocrinology · doi:10.1210/en.2012-2056 · Cited by 112 · see citing works

Ghrelin Inhibits the Proliferative Activity of Immature Leydig Cells in Vivo and Regulates Stem Cell Factor Messenger Ribonucleic Acid Expression in Rat Testis

Barreiro, M. L., Gaytán, F., Castellano, J. M., et al. (2004) · Endocrinology · doi:10.1210/en.2004-0732 · Cited by 110 · see citing works

High dose growth hormone treatment induces acceleration of skeletal maturation and an earlier onset of puberty in children with idiopathic short stature

Kamp, G. A. (2002) · Archives of Disease in Childhood · doi:10.1136/adc.87.3.215 · Cited by 109 · see citing works

Effect of insulin-like growth factor-I treatment on serum androgens and testicular and penile size in males with Laron syndrome (primary growth hormone resistance)

Laron, Z., & Klinger, B. (1998) · European Journal of Endocrinology · doi:10.1530/eje.0.1380176 · Cited by 107 · see citing works

The Role of Growth Hormone and Insulin-Like Growth Factor I in the Regulation of Male Reproductive Function

Spiteri-Grech, J., & Nieschlag, E. (2008) · Hormone Research · doi:10.1159/000182566 · Cited by 105 · see citing works

Prostatic Hyperplasia: An Unknown Feature of Acromegaly

Colao, A., Marzullo, P., Ferone, D., et al. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.3.4645 · Cited by 104 · see citing works

Effects of Insulin-Like Growth Factor I on Steroidogenic Enzyme Expression Levels in Mouse Leydig Cells

Wang, G., O’Shaughnessy, P. J., Chubb, C., Robaire, B., & Hardy, M. P. (2003) · Endocrinology · doi:10.1210/en.2003-0563 · Cited by 101 · see citing works

A Prospective Study of Serum Insulin-Like Growth Factor I (IGF-I) and IGF-Binding Protein-3 in 942 Healthy Infants: Associations with Birth Weight, Gender, Growth Velocity, and Breastfeeding

Chellakooty, M., Juul, A., Boisen, K. A., Damgaard, I. N., Kai, C. M., Schmidt, I. M., Petersen, J. H., Skakkebæk, N. E., & Main, K. M. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0950 · Cited by 100 · see citing works

Pubertal Growth and Final Height in Hypopituitary Boys: A Minor Role of Bone Age at Onset of Puberty*

Bourguignon, J.-P., Vandeweghe, M., Vanderschueren‐Lodeweyckx, M., Malvaux, P., Wolter, R. A., Caju, M. D., & Ernould, C. (1986) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-63-2-376 · Cited by 100 · see citing works

Andrology: Insulin-like growth factor-I and 2-macroglobulin in seminal plasma correlate with semen quality

Glander, H. ‐., Kratzsch, J., Weisbrich, C., et al. (1996) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a019136 · Cited by 99 · see citing works

Insulin-Like Growth Factor-I Activates KiSS-1 Gene Expression in the Brain of the Prepubertal Female Rat

Hiney, J. K., Srivastava, V. K., Pine, M. D., & Dees, W. L. (2008) · Endocrinology · doi:10.1210/en.2008-0954 · Cited by 99 · see citing works

Higher Levels of IGF-I and Adrenal Androgens at Age 8 Years Are Associated with Earlier Age at Menarche in Girls

Thankamony, A., Ong, K. K., Ahmed, M. L., Ness, A., Holly, J. M. P., & Dunger, D. B. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-3261 · Cited by 99 · see citing works

Penis and testicular size in patients with growth hormone insufficency.

Laron, Z., & Sarel, R. (1970) · Acta Endocrinologica · doi:10.1530/acta.0.0630625 · Cited by 96 · see citing works

Hypogonadism in patients with acromegaly: data from the multi‐centre acromegaly registry pilot study

Katznelson, L., Kleinberg, D., Vance, M. L., Stravou, S., Pulaski, K. J., Schoenfeld, D. A., Hayden, D. L., Wright, M. E., Woodburn, C. J., & Klibanski, A. (2001) · Clinical Endocrinology · doi:10.1046/j.1365-2265.2001.01214.x · Cited by 95 · see citing works

Serum concentrations of free and total insulin‐like growth factor‐I, IGF binding proteins ‐1 and‐3 and IGFBP‐3 protease activity in boys with normal or precocious puberty

Juul, A., Flyvbjerg, A., Frystyk, J., et al. (1996) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1996.711531.x · Cited by 95 · see citing works

Growth Hormone and Insulin-Like Growth Factor I Treatment Increase Testicular Luteinizing Hormone Receptors and Steroidogenic Responsiveness of Growth Hormone Deficient Dwarf Mice*

CHATELAIN, P. G., Sánchez, P., & Saez, J. M. (1991) · Endocrinology · doi:10.1210/endo-128-4-1857 · Cited by 94 · see citing works

Growth Hormone Regulates Steroidogenic Acute Regulatory Protein Expression and Steroidogenesis in Leydig Cell Progenitors

Kanzaki, M., & Morris, P. L. (1999) · Endocrinology · doi:10.1210/endo.140.4.6661 · Cited by 93 · see citing works

Does milk intake promote prostate cancer initiation or progression via effects on insulin-like growth factors (IGFs)? A systematic review and meta-analysis

Harrison, S., Lennon, R. J., Holly, J. M. P., Higgins, J. P. T., Gardner, M. P., Perks, C. M., Gaunt, T. R., Tan, V. Y., Borwick, C., Emmett, P. M., et al. (2017) · Cancer Causes & Control · doi:10.1007/s10552-017-0883-1 · Cited by 91 · see citing works

Delay of Puberty Onset in Females due to Suppression of Growth Hormone*

Ramaley, J. A., & Phares, C. K. (1980) · Endocrinology · doi:10.1210/endo-106-6-1989 · Cited by 89 · see citing works

Kitcre knock-in mice fail to fate-map cardiac stem cells

Vicinanza, C., Aquila, I., Cianflone, E., et al. (2018) · Nature · doi:10.1038/nature25771 · Cited by 88 · see citing works

Effect of Growth Hormone (GH) and Insulin-Like Growth Factor I on Prostate Diseases: An Ultrasonographic and Endocrine Study in Acromegaly, GH Deficiency, and Healthy Subjects

Colao, A., Marzullo, P., Spiezia, S., et al. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.84.6.5776 · Cited by 86 · see citing works

Growth hormone secretion patterns in relation to LH and testosterone secretion throughout normal male puberty

WENNINK, J. M. B., de Waal, H. A. D., Schoemaker, R. C., Blaauw, G., van den Braken, C., & Schoemaker, J. (1990) · European Journal of Endocrinology · doi:10.1530/acta.0.1230263 · Cited by 84 · see citing works

Transient Postnatal Gonadal Activation and Growth Velocity in Infancy

Kiviranta, P., Kuiri‐Hänninen, T., Saari, A., Lamidi, M., Dunkel, L., & Sankilampi, U. (2016) · PEDIATRICS · doi:10.1542/peds.2015-3561 · Cited by 84 · see citing works

Inhibin B, AMH, but not INSL3, IGF1 or DHEAS support differentiation between constitutional delay of growth and puberty and hypogonadotropic hypogonadism

Rohayem, J., Nieschlag, E., Kliesch, S., & Zitzmann, M. (2015) · Andrology · doi:10.1111/andr.12088 · Cited by 83 · see citing works

Growth hormone, prolactin, and sexuality

Galdiero, M., Pivonello, R., Grasso, L. F. S., Cozzolino, A., & Colao, A. (2014) · Journal of Endocrinological Investigation · doi:10.1007/bf03345805 · Cited by 82 · see citing works

Developmental, Stage-Specific, and Hormonally Regulated Expression of Growth Hormone Secretagogue Receptor Messenger RNA in Rat Testis1

Barreiro, M. L., Suominen, J. S., Gaytán, F., Pinilla, L., Chopin, L. K., Casanueva, F. F., Diéguez, C., Aguilar, E., Toppari, J., & Tena‐Sempere, M. (2003) · Biology of Reproduction · doi:10.1095/biolreprod.102.008862 · Cited by 82 · see citing works

Gender Differences in the Effects of Long Term Growth Hormone (GH) Treatment on Bone in Adults with GH Deficiency

Johansson, A. G. (1999) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.84.6.2002 · Cited by 82 · see citing works

The Effects of Growth Hormone Therapy on Spontaneous Sexual Development

Stanhope, R. G., Albanese, A., Hindmarsh, P. C., & Brook, C. G. D. (2008) · Hormone Research · doi:10.1159/000182563 · Cited by 80 · see citing works

Follicle-Stimulating Hormone Amplifies Insulin-Like Growth Factor I-Mediated Activation of AKT/Protein Kinase B Signaling in Immature Rat Sertoli Cells

Khan, S. A., Ndjountche, L., Pratchard, L., SPICER, L. J., & Davis, J. S. (2002) · Endocrinology · doi:10.1210/endo.143.6.8838 · Cited by 78 · see citing works

Estrogen Up-Regulates Hepatic Expression of Suppressors of Cytokine Signaling-2 and -3 in Vivo and in Vitro

Leong, G. M., Movérare, S., Brce, J., Doyle, N., Sjögren, K., Dahlman‐Wright, K., Gustafsson, J.-Å., Ho, K. K. Y., Ohlsson, C., & Leung, K. (2004) · Endocrinology · doi:10.1210/en.2004-0061 · Cited by 77 · see citing works

Ontogenesis of Leptin Receptor in Rat Leydig Cells1

Caprio, M., Fabbrini, E., Ricci, G., Basciani, S., Gnessi, L., Arizzi, M., Carta, A. R., Martino, M. U. D., Isidori, A. M., Frajese, G. V., et al. (2003) · Biology of Reproduction · doi:10.1095/biolreprod.102.007831 · Cited by 76 · see citing works

Puberty Is Delayed in Male Growth Hormone Receptor Gene—Disrupted Mice

KEENE, D. E., Suescun, M. O., BOSTWICK, M. G., Chandrashekar, V., Bartke, A., & Kopchick, J. J. (2002) · Journal of Andrology · doi:10.1002/j.1939-4640.2002.tb02308.x · Cited by 75 · see citing works

Unfavorable effects of growth hormone therapy on the final height of boys with short stature not caused by growth hormone deficiency

Kawai, M., Momoi, T., Yorifuji, T., et al. (1997) · The Journal of Pediatrics · doi:10.1016/s0022-3476(97)70344-5 · Cited by 73 · see citing works

Ghrelin Expression in Human Testis and Serum Testosterone Level

Ishikawa, T., Fujioka, H., Ishimura, T., Takenaka, A., & Fujisawa, M. (2007) · Journal of Andrology · doi:10.2164/jandrol.106.000810 · Cited by 70 · see citing works

Cotreatment with growth hormone for induction of spermatogenesis in patients with hypogonadotropic hypogonadism

Shoham, Z., Conway, G. S., Ostergaard, H., Lahlou, N., Bouchard, P., & Jacobs, H. S. (1992) · Fertility and Sterility · doi:10.1016/s0015-0282(16)55023-7 · Cited by 70 · see citing works

Exploring the role of ghrelin as novel regulator of gonadal function

Tena‐Sempere, M. (2005) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2005.02.001 · Cited by 69 · see citing works

Both Estrogen Receptor α and β Stimulate Pituitary GH Gene Expression

Avtanski, D. B., Novaira, H. J., Wu, S., Romero, C. J., Kineman, R. D., Luque, R. M., Wondisford, F. E., & Radovick, S. (2013) · Molecular Endocrinology · doi:10.1210/me.2013-1245 · Cited by 65 · see citing works

Serum insulin-like growth factor I (IGF-I) and IGF-binding protein 3 levels are increased in central precocious puberty: effects of two different treatment regimens with gonadotropin-releasing hormone agonists, without or in combination with an antiandrogen (cyproterone acetate)

Juul, A., Scheike, T., Nielsen, C. T., Krabbe, S., Müller, J., & Skakkebæk, N. E. (1995) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.80.10.7559897 · Cited by 65 · see citing works

IGF-I treatment increases motility and improves morphology of immature spermatozoa in the GH-deficient dwarf (dw/dw) rat

Vickers, M. H., Casey, P. J., Champion, Z. J., Gravance, C. G., & Breier, B. H. (1999) · Growth Hormone & IGF Research · doi:10.1054/ghir.1999.0114 · Cited by 61 · see citing works

Homozygous mutation of the IGF1 receptor gene in a patient with severe pre- and postnatal growth failure and congenital malformations

Gannagé‐Yared, M., Klammt, J., Chouery, É., Corbani, S., Megarbane, H. A. R., Ghoch, J. A., Choucair, N., Pfäffle, R. W., & Mégarbané, A. (2012) · European Journal of Endocrinology · doi:10.1530/eje-12-0701 · Cited by 59 · see citing works

Activation of the Somatotropic Axis by Testosterone in Adult Men: Evidence for a Role of Hypothalamic Growth Hormone-Releasing Hormone

Bondanelli, M., Ambrosio, M. R., Margutti, A., Franceschetti, P., Zatelli, M. C., & degli Uberti, E. C. (2003) · Neuroendocrinology · doi:10.1159/000071310 · Cited by 58 · see citing works

Effects of Growth Hormone Replacement Therapy on IGF-Related Parameters and on the Pituitary-Gonadal Axis in GH-Deficient Males

Juul, A., Andersson, A., Pedersen, S. A., Jørgensen, J. O. L., Christiansen, J. S., Groome, N. P., & Skakkebæk, N. E. (1998) · Hormone Research in Paediatrics · doi:10.1159/000023186 · Cited by 58 · see citing works

Interactions of insulin-like growth factor-I, insulin and estradiol with GnRH-stimulated luteinizing hormone release from female rat gonadotrophs

Xia, Y., Weiss, J., Polack, S., Diedrich, K., & Ortmann, O. (2001) · European Journal of Endocrinology · doi:10.1530/eje.0.1440073 · Cited by 58 · see citing works

Desensitization of the Growth Hormone-Induced Janus Kinase 2 (Jak 2)/Signal Transducer and Activator of Transcription 5 (Stat5)-Signaling Pathway Requires Protein Synthesis and Phospholipase C

Fernández‐Pérez, L., Flores‐Morales, A., Lahuna, O., Slíva, D., Norstedt, G., Haldosén, L.-A., Mode, A., & Gustafsson, J.-Α. (1998) · Endocrinology · doi:10.1210/endo.139.4.5931 · Cited by 56 · see citing works

Sex Steroids, Precursors, and Metabolite Deficiencies in Men With Isolated Hypogonadotropic Hypogonadism and Panhypopituitarism: A GCMS-Based Comparative Study

Giton, F., Trabado, S., Maione, L., Sarfati, J., Bouc, Y. L., Brailly‐Tabard, S., Fiet, J., & Young, J. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-2658 · Cited by 55 · see citing works

The Effect of Chronic Treatment With GH on Gonadal Function in Men With Isolated GH Deficiency

Carani, C., Granata, A., De Rosa, M., Garau, C., Zarrilli, S., Paesano, L., Colao, A., Marrama, P., & Lombardi, G. (1999) · European Journal of Endocrinology · doi:10.1530/eje.0.1400224 · Cited by 54 · see citing works

Growth hormone treatment of subfertile males

Ovesen, P., Jørgensen, J. O. L., Ingerslev, H. J., Ho, K. K. Y., Ørskov, H., & Christiansen, J. S. (1996) · Fertility and Sterility · doi:10.1016/s0015-0282(16)58456-8 · Cited by 54 · see citing works

Metabolic Clearance Rates of Synthetic Human Growth Hormone in Children, Adult Women, and Adult Men*

ROSENBAUM, M. S., & Gertner, J. M. (1989) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-69-4-821 · Cited by 52 · see citing works

Growth hormone secretion patterns in relation to LH and estradiol secretion throughout normal female puberty

WENNINK, J. M. B., de Waal, H. A. D., Schoemaker, R. C., Blaauw, G., van den Braken, C., & Schoemaker, J. (1991) · European Journal of Endocrinology · doi:10.1530/acta.0.1240129 · Cited by 52 · see citing works

Effect of Growth Hormone Dose on Bone Maturation and Puberty in Children with Idiopathic Short Stature

Crowe, B. J., Rekers-Mombarg, L. T. M., Robling, K., Wolka, A. M., Cutler, G. B., & Jan, M. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0891 · Cited by 51 · see citing works

Tall Stature without Growth Hormone: Four Male Patients with Aromatase Deficiency

Rochira, V., Zirilli, L., MAFFEI, L. E., Premrou, V., Aranda, C., Baldi, M., Ghigo, E., Aimaretti, G., Carani, C., & Lanfranco, F. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-1743 · Cited by 50 · see citing works

Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury

Siena, S. D., Gimmelli, R., Nori, S. L., et al. (2016) · Cell Death and Disease · doi:10.1038/cddis.2016.205 · Cited by 50 · see citing works

Impact of gender and androgen status on IGF-I levels in normal and GH-deficient adults

Fisker, S., Jørgensen, J. O. L., Vahl, N., Ørskov, H., & Christiansen, J. (1999) · European Journal of Endocrinology · doi:10.1530/eje.0.1410601 · Cited by 47 · see citing works

Delay of Puberty Onset in Males Due to Suppression of Growth Hormone

Ramaley, J. A., & Phares, K. (2008) · Neuroendocrinology · doi:10.1159/000123475 · Cited by 45 · see citing works

Micropenis Secondary to Growth Hormone Deficiency: Does Treatment with Growth Hormone Alone Result in Adequate Penile Growth?

Levy, J. B., & Husmann, D. A. (1996) · The Journal of Urology · doi:10.1016/s0022-5347(01)66003-8 · Cited by 45 · see citing works

Developmental Changes in Hypothalamic Insulin-Like Growth Factor-1: Relationship to Gonadotropin-Releasing Hormone Neurons

Daftary, S. S., & Gore, A. C. (2003) · Endocrinology · doi:10.1210/en.2002-221025 · Cited by 44 · see citing works

Effect of growth hormone therapy in men with severe idiopathic oligozoospermia

Lee, K., Ng, S.-C., Lee, P. S., Bongso, A., Taylor, E., Lin, T.-K., & Ratnam, S. S. (1995) · European Journal of Endocrinology · doi:10.1530/eje.0.1320159 · Cited by 43 · see citing works

Insulin-like growth factor I enhances gonadotropin-releasing hormone-stimulated luteinizing hormone release from bovine anterior pituitary cells

HASHIZUME, T., Kumahara, A., Fujino, M., & Okada, K. (2002) · Animal Reproduction Science · doi:10.1016/s0378-4320(01)00190-7 · Cited by 40 · see citing works

Short-Term Suppression of GH and IGF-I Levels Improves Gonadal Function and Sperm Parameters in Men with Acromegaly

Colao, A., Rosa, M. D., Pivonello, R., Balestrieri, A., Cappabianca, P., Sarno, A. D., Rochira, V., Carani, C., & Lombardi, G. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020453 · Cited by 40 · see citing works

Serum and seminal plasma insulin-like growth factor-1 in male infertility

Lee, H. S., Park, Y., Lee, J. S., & Seo, J. T. (2016) · Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine · doi:10.5653/cerm.2016.43.2.97 · Cited by 40 · see citing works

GROWTH OF MALES WITH IDIOPATHIC HYPOPITUITARISM WITHOUT GROWTH HORMONE TREATMENT

ten Bosch, J. J. V. D. W., & Bot, A. G. M. (1990) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1990.tb00917.x · Cited by 39 · see citing works

Effect of Two Years of Growth Hormone and Insulin-Like Growth Factor-I Suppression on Prostate Diseases in Acromegalic Patients1

Colao, A. A. L., Marzullo, P., Spiezia, S., Giaccio, A., Ferone, D., Cerbone, G., Sarno, A. D., & Lombardi, G. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.10.6907 · Cited by 39 · see citing works

Clomiphene Citrate for Treatment of Acromegaly Not Controlled by Conventional Therapies

Duarte, F. H. G., Jallad, R. S., & Bronstein, M. D. (2015) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2014-3913 · Cited by 39 · see citing works

The role of growth hormone in fetal mouse reproductive tract differentiation.

Nguyen, A., Chandorkar, A. K., & Gupta, C. (1996) · Endocrinology · doi:10.1210/endo.137.9.8756530 · Cited by 38 · see citing works

IDENTIFICATION OF INSULIN-LIKE GROWTH FACTOR (IGF)-1 RECEPTOR IN HUMAN SPERM CELL

Naz, R. K., & Padman, P. (1999) · Archives of Andrology · doi:10.1080/014850199262661 · Cited by 38 · see citing works

Effect of growth hormone treatment on testicular function, puberty, and adrenarche in boys with non-growth hormone–deficient short stature: A randomized, double-blind, placebo-controlled trial

Leschek, E., Troendle, J. F., Yanovski, J. A., et al. (2001) · The Journal of Pediatrics · doi:10.1067/mpd.2001.111332 · Cited by 36 · see citing works

ENDOCRINOLOGY AND ADOLESCENCE: Dealing with transition in young patients with pituitary disorders

Sbardella, E., Pozza, C., Isidori, A. M., & Grossman, A. B. (2019) · European Journal of Endocrinology · doi:10.1530/eje-19-0298 · Cited by 36 · see citing works

Erectile Dysfunction Is Common among Men with Acromegaly and Is Associated with Morbidities Related to the Disease

Lotti, F., Rochira, V., Pivonello, R., Santi, D., Galdiero, M., Maseroli, E., Antonio, B., Faustini‐Fustini, M., Peri, A., Sforza, A., et al. (2015) · The Journal of Sexual Medicine · doi:10.1111/jsm.12859 · Cited by 35 · see citing works

Role of IGFs and Insulin in the Human Testis During Postnatal Activation: Differentiation of Steroidogenic Cells

Berensztein, E. B., Baquedano, M. S., Pepe, C. M., Costanzo, M., Saraco, N. I., Ponzio, R., Rivarola, M. A., & Belgorosky, A. (2008) · Pediatric Research · doi:10.1203/pdr.0b013e31816c8ffc · Cited by 35 · see citing works

Hormone‐related diseases and prostate cancer: An English national record linkage study

Watts, E. L., Goldacre, R., Key, T. J., Allen, N. E., Travis, R. C., & Perez‐Cornago, A. (2019) · International Journal of Cancer · doi:10.1002/ijc.32808 · Cited by 35 · see citing works

Serum levels of human growth hormone during different penile conditions in the cavernous and systemic blood of healthy men and patients with erectile dysfunction

Becker, A. J., Ückert, S., Stief, C. G., Scheller, F., Knapp, W. H., Hartmann, U. H., Brabant, G. E., & Udo Jonas, A. (2002) · Urology · doi:10.1016/s0090-4295(01)01594-1 · Cited by 34 · see citing works

Growth hormone and the steroid binding β-globulin of human plasma

MOOR, P. D., Heynes, W., & Bouillon, R. (1972) · Journal of Steroid Biochemistry · doi:10.1016/0022-4731(72)90105-7 · Cited by 34 · see citing works

Androgen Receptor Regulation of Local Growth Hormone in Prostate Cancer Cells

Recouvreux, M. V., Wu, B. J., Gao, A. C., Zonis, S., Chesnokova, V., Bhowmick, N. A., Chung, L. W. K., & Melmed, S. K. (2017) · Endocrinology · doi:10.1210/en.2016-1939 · Cited by 34 · see citing works

Growth hormone status in patients with maturation arrest of spermatogenesis

Shimonovitz, S., Zacut, D., Chetrit, A. B., & Ron, M. (1993) · Human Reproduction · doi:10.1093/oxfordjournals.humrep.a138166 · Cited by 33 · see citing works

Role of some vasoactive mediators in patients with erectile dysfunction: their relationship with angiotensin-converting enzyme and growth hormone

Hamed, E., Meki, A., Gaafar, A., & Hamed, S. A. (2003) · International Journal of Impotence Research · doi:10.1038/sj.ijir.3901059 · Cited by 32 · see citing works

Why Do Normal Children Have Acromegalic Levels of IGF-I During Puberty?

Juul, A., & Skakkebæk, N. E. (2019) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2018-02099 · Cited by 31 · see citing works

Growth, development, puberty and adult height before and during treatment in children with congenital isolated growth hormone deficiency

Smuel, K., Kauli, R., Lilos, P., & Laron, Z. (2015) · Growth Hormone & IGF Research · doi:10.1016/j.ghir.2015.05.001 · Cited by 30 · see citing works

Effect of Growth Hormone (GH) and/or Testosterone Replacement on the Prostate in GH-Deficient Adult Patients

Colao, A., Somma, C. D., Spiezia, S., Filippella, M., Pivonello, R., & Lombardi, G. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-020812 · Cited by 29 · see citing works

Postnatal Changes in Testicular Position Are Associated With IGF-I and Function of Sertoli and Leydig Cells

Koskenniemi, J. J., Virtanen, H. E., Wohlfahrt‐Veje, C., Löyttyniemi, E., Skakkebæk, N. E., Juul, A., Andersson, A., Main, K. M., & Toppari, J. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-01889 · Cited by 29 · see citing works

Effect of Two Years of Growth Hormone and Insulin-Like Growth Factor-I Suppression on Prostate Diseases in Acromegalic Patients

Colao, A. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.85.10.3754 · Cited by 29 · see citing works

The Effect of Growth Hormone Administration on Testicular Response During Gonadotropin Therapy in Subjects With Combined Gonadotropin and Growth Hormone Deficiencies

Balducci, R., Toscano, V., Mangiantini, A., Bianchi, P., Guglielmi, R., & Boscherini, B. (1993) · Acta Endocrinologica · doi:10.1530/acta.0.1280019 · Cited by 28 · see citing works

Influence of Growth Hormone Treatment on Pubertal Timing and Pubertal Growth in Children with Idiopathic Short Stature

Rekers-Mombarg, L. T. M., Kamp, G. A., Massa, G., Wit, J. M., & Dutch Growth Hormone Working Group (1999) · Journal of Pediatric Endocrinology and Metabolism · doi:10.1515/jpem.1999.12.5.611 · Cited by 28 · see citing works

Can growth hormone treatment in boys without growth hormone deficiency impair testicular function?

Bertelloni, S., Baroncelli, G. I., Viacava, P., et al. (1999) · The Journal of Pediatrics · doi:10.1016/s0022-3476(99)70136-8 · Cited by 26 · see citing works

Growth Hormone Directly Stimulates Testosterone and Oestradiol Secretion by Rat Leydig Cells in vitro and Modulates The Effects of LH and T3.

Maran, R. R. M., Sivakumar, R., Bhaskaran, R. S., Valli, G., RAVICHANDRAN, K., Arunakaran, J., & Aruldhas, M. M. (2000) · Endocrine Journal · doi:10.1507/endocrj.47.111 · Cited by 26 · see citing works

Recombinant-growth hormone (rec-hGH) therapy in infertile men with idiopathic oligozoospermia.

Radicioni, A. F., Paris, E., Dondero, F., Bonifacio, & Isidori, A. M. (1994) · PubMed · Cited by 26 · see citing works

Growth hormone ( GH ) activity is associated with increased serum oestradiol and reduced Anti‐ M üllerian Hormone in healthy male volunteers treated with GH and a GH antagonist

Andreassen, M., Frystyk, J., Faber, J., Kristensen, L. Ø., & Juul, A. (2013) · Andrology · doi:10.1111/j.2047-2927.2013.00096.x · Cited by 24 · see citing works

Management of idiopathic growth hormone deficient patients during puberty.

Price, D. A., Shalet, S. M., & Clayton, P. (1988) · PubMed · Cited by 24 · see citing works

Relationships between Puberty and Growth at Adolescence in Growth-Hormone-Deficient Males: Effect of Growth Hormone and of Associated Gonadal Suppression Therapy

Tanaka, T., Yoshizawa, A., Tanae, A., et al. (2008) · Hormone Research · doi:10.1159/000181593 · Cited by 23 · see citing works

Ultradian oscillation in somatostatin binding in the arcuate nucleus of adult male rats.

Tannenbaum, G. S., Farhadi-Jou, F., & Beaudet, A. (1993) · Endocrinology · doi:10.1210/endo.133.3.8103446 · Cited by 22 · see citing works

Effect of human growth hormone therapy on penile and testicular size in boys with isolated growth hormone deficiency: first year of treatment.

Laron, Z., Mimouni, F. B., & Pertzelan, A. (1983) · PubMed · Cited by 20 · see citing works

Prostate cancer and acromegaly

Corrêa, L. L., Lima, G. A. B., Paiva, H. B., et al. (2009) · Arquivos Brasileiros de Endocrinologia & Metabologia · doi:10.1590/s0004-27302009000800009 · Cited by 20 · see citing works

Continuous subcutaneous infusion of low dose growth hormone decreases serum sex‐hormone binding globulin and testosterone concentrations in moderately obese middle‐aged men

Oscarsson, J., Lindstedt, G., Lundberg, P., et al. (1996) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1996.635457.x · Cited by 20 · see citing works

Gender differences in serum GH and IGF-I levels and the GH response to dynamic tests in patients with acromegaly

Tanaka, S. A., Fukuda, I., Hizuka, N., & Takano, K. (2010) · Endocrine Journal · doi:10.1507/endocrj.k09e-342 · Cited by 19 · see citing works

Ultrastructural immunolocalization of IGF-1 and insulin receptors in rat pituitary culture: evidence of a functional interaction between gonadotroph and lactotroph cells

Gutiérrez, S., Mukdsi, J. H., Aoki, A., Torres, A. I., Soler, A. P., & Orgnero, E. M. (2006) · Cell and Tissue Research · doi:10.1007/s00441-006-0283-4 · Cited by 19 · see citing works

ABSENCE OF EFFECT OF RECOMBINANT GROWTH HORMONE TO CLASSIC GONADOTROPIN TREATMENT ON SPERMATOGENESIS OF PATIENTS WITH SEVERE HYPOGONADOTROPIC HYPOGONADISM

Giagulli, V. A. (1999) · Archives of Andrology · doi:10.1080/014850199262724 · Cited by 18 · see citing works

Age at first ejaculation (spermarche)--the overlooked milestone in male development.

Laron, Z. (2010) · PubMed · Cited by 17 · see citing works

Oral estroprogestin: an alternative low cost therapy for women with postoperative persistent acromegaly?

Vallette, S., & Serri, O. (2010) · Pituitary · doi:10.1007/s11102-010-0236-5 · Cited by 17 · see citing works

Sex Steroids, GHRH, Somatostatin, IGF-I, and IGFBP-1 Modulate Ghrelin's Dose-Dependent Drive of Pulsatile GH Secretion in Healthy Older Men

Veldhuis, J. D., Norman, C., Miles, J. M., & Bowers, C. Y. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2012-2567 · Cited by 17 · see citing works

Gonadal function and response to growth hormone (GH) in boys with isolated GH deficiency and to GH and gonadotropins in boys with multiple pituitary hormone deficiencies

Tatò, L., Zamboni, G., Antoniazzi, F., & Piubello, G. (1996) · Fertility and Sterility · doi:10.1016/s0015-0282(16)58222-3 · Cited by 17 · see citing works

Does Growth Hormone Treatment Influence Pubertal Development in Short Children?

Albin, A., Ankarberg‐Lindgren, C., Tuvemo, T., et al. (2011) · Hormone Research in Paediatrics · doi:10.1159/000329743 · Cited by 15 · see citing works

Spontaneous growth hormone secretion increases during puberty in normal girls and boys

Rose, S. R., Municchi, G., Barnes, K. M., et al. (1992) · Pediatric Nephrology · doi:10.1007/bf00878392 · Cited by 15 · see citing works

Puberty in Children with Idiopathic Growth Hormone Deficiency on Growth Hormone Treatment: Preliminary Analysis of the Data from the Kabi Pharmacia International Growth Study

Price, D. (1991) · Acta Paediatrica · doi:10.1111/j.1651-2227.1991.tb12061.x · Cited by 14 · see citing works

Three Cases of Congenital Growth Hormone Deficiency with Micropenis and Hypospadias: What Does Growth Hormone Have to Do with It?

Urzola, A. V., Léger, J., & Czernichow, P. (1999) · Hormone Research in Paediatrics · doi:10.1159/000023324 · Cited by 14 · see citing works

Aromatized Estrogens Amplify Nocturnal Growth Hormone Secretion in Testosterone-Replaced Older Hypogonadal Men

Roelfsema, F., Yang, R. J., Takahashi, P. Y., Erickson, D. Z., Bowers, C. Y., & Veldhuis, J. D. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2018-00755 · Cited by 14 · see citing works

Growth Hormone Deficiency Causing Micropenis: Lessons Learned From a Well-Adjusted Adult

Lee, P. A., Mazur, T., Houk, C. P., et al. (2018) · PEDIATRICS · doi:10.1542/peds.2017-4168 · Cited by 13 · see citing works

Effect of recombinant hGH (rhGH) replacement on gonadal function in male patients with organic adult‐onset GH deficiency

Giavoli, C., Ferrante, E., Ermetici, F., Bergamaschi, S., Ronchi, C. L., Lania, A. G., Ambrosi, B., Spada, A., & Beck‐Peccoz, P. (2006) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2006.02655.x · Cited by 12 · see citing works

A prospective pilot study of co-treatment with growth hormone and gonadotropins for improving spermatogenesis in normogonadotropic patients with severe oligoteratoasthenospermia

Zalel, Y., Draysen, E., Goldshmit, R., Zadik, Z., & Shoham, Z. (1996) · Gynecological Endocrinology · doi:10.3109/09513599609041266 · Cited by 12 · see citing works

Acromegaly and ultrasound: how, when and why?

Parolin, M., Dassie, F., Vettor, R., & Maffei, P. (2019) · Journal of Endocrinological Investigation · doi:10.1007/s40618-019-01111-9 · Cited by 12 · see citing works

Effect of Growth Hormone Replacement Therapy on Pituitary Hormone Secretion and Hormone Replacement Therapies in GHD Adults

Hubina, E., Mersebach, H., Rasmussen, Å. K., Juul, A., Sneppen, S. B., Góth, M., & Feldt‐Rasmussen, U. (2004) · Hormone Research in Paediatrics · doi:10.1159/000076538 · Cited by 11 · see citing works

Short boys treated with growth hormone show normal progression of testicular size and achieve normal serum testosterone concentrations

Ankarberg‐Lindgren, C., Norjavaara, E., & Wikland, K. (2002) · European Journal of Endocrinology · doi:10.1530/eje.0.1460681 · Cited by 11 · see citing works

Prostatic hyperplasia in acromegaly, a myth or reality: a case–control study

Kumar, S., Yadav, R. N., Gupta, P., et al. (2014) · European Journal of Endocrinology · doi:10.1530/eje-14-0698 · Cited by 11 · see citing works

Effect of growth hormone cotreatment with human chorionic gonadotropin in testicular steroidogenesis and seminal insulin-like growth factor-1 in oligozoospermia

Anapliotou, M., Evagellou, E., Kastanias, I., Liparaki, M., Psara, P., & Goulandris, N. (1996) · Fertility and Sterility · doi:10.1016/s0015-0282(16)58458-1 · Cited by 11 · see citing works

Pubertal development in male hypopituitarism

Mart�nez, A., Heinrich, J. J., Rivarola, M. A., et al. (1986) · European Journal of Pediatrics · doi:10.1007/bf00439244 · Cited by 9 · see citing works

Testicular function in boys previously treated with recombinant-human growth hormone for non-growth hormone-deficient short stature

Radicioni, A. F., Paris, E., Marco, E. D., Anzuini, A., Gandini, L., & Lenzi, A. (2007) · Journal of Endocrinological Investigation · doi:10.1007/bf03349240 · Cited by 9 · see citing works

Prepubertal Children with Growth Hormone Deficiency Treated for Four Years with Growth Hormone Experience Dose-Dependent Increase in Height, but Not in the Rate of Puberty Initiation

Rogol, A. D., Cohen, P., Weng, W., Kappelgaard, A., & Germak, J. A. (2013) · Hormone Research in Paediatrics · doi:10.1159/000353429 · Cited by 9 · see citing works

Growth hormone insensitivity: Mexican case report

Castilla‐Cortázar, I., Ita, J. R. D., Aguirre, G. A., et al. (2017) · Endocrinology Diabetes and Metabolism Case Reports · doi:10.1530/edm-17-0126 · Cited by 9 · see citing works

Semen quality in hypogonadal acromegalic patients

Andreassen, M., Juul, A., Feldt‐Rasmussen, U., & Jørgensen, N. (2019) · Pituitary · doi:10.1007/s11102-019-01018-x · Cited by 9 · see citing works

GH/IGF‐I axis in azoospermia in primary and secondary hypogonadism: a study before and during replacement therapy

CARANI, Mantovani, PROCOPIO, Rió, G. D., ROSSETTO, & Granata (1999) · International Journal of Andrology · doi:10.1046/j.1365-2605.1999.00169.x · Cited by 7 · see citing works

Prostatic Hyperplasia: An Unknown Feature of Acromegaly

Colao, A., Marzullo, P., Ferone, D., et al. (1998) · The Journal of Urology · doi:10.1016/s0022-5347(01)62629-6 · Cited by 5 · see citing works

Acromegaly Presenting as Erectile Dysfunction: Case Reports and Review of the Literature.

Raju, J., Shipman, K. E., Inglis, J. A., & Gama, R. M. (2015) · PubMed Central · Cited by 4 · see citing works

Prostatic hyperplasia in acromegaly, a myth or reality: a case–control study

Kumar, S., Yadav, R. N., Gupta, P., et al. (2015) · European Journal of Endocrinology · doi:10.1530/eje-14-0698e · Cited by 2 · see citing works

Role of the GH-IGF1 Axis on the Hypothalamus-Pituitary-Testicular Axis Function: Lessons From Laron Syndrome

Cannarella, R., Crafa, A., La Vignera, S., Condorelli, R. A., & Calogero, A. E. (2021) · Endocrine Connections · doi:10.1530/ec-21-0252 · Cited by 16 · see citing works

Growth Hormone Is Beneficial for Induction of Spermatogenesis in Adult Patients With Congenital Combined Pituitary Hormone Deficiency

Zhu, Y., Nie, M., Wang, X., Huang, Q., Yu, B., Zhang, R., Zhang, J., Sun, B., Mao, J., & Wu, X. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.868047 · Cited by 2 · see citing works

Autocrine/paracrine involvement of insulin‐like growth factor‐I and its receptor in chronic lymphocytic leukaemia

Schillaci, R., Galeano, A. C., Becú‐Villalobos, D., et al. (2005) · British Journal of Haematology · doi:10.1111/j.1365-2141.2005.05579.x · Cited by 34 · see citing works

Simultaneous over-expression of insulin-like growth factor-II (IGF II) and IGF-II receptor (IGF-II R) genes in human primary cancer-implication of autocrine and paracrine mechanism in autonomous growth of hepatic cancer

Zhou, X., Gu, J., Cheng, Y., et al. (1992) · Chinese Journal of Cancer Research · doi:10.1007/bf02997211 · Cited by 2 · see citing works

Inhibition regulation of apoptosis by insulin-like growth factor(IGF)-1

Li, K. (2007) · Shengming kexue · Cited by 3 · see citing works

Aging and hormones of the hypothalamo-pituitary axis: Gonadotropic axis in men and somatotropic axes in men and women

Veldhuis, J. D. (2008) · Ageing Research Reviews · doi:10.1016/j.arr.2007.12.005 · Cited by 98 · see citing works

Discordance in the Dependence on Kisspeptin Signaling in Mini Puberty vs Adolescent Puberty: Human Genetic Evidence

Shahab, M., Lippincott, M. F., Chan, Y.-M., Davies, A., Merino, P. M., Plummer, L., Verónica Mericq, G., & Seminara, S. B. (2018) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-02636 · Cited by 13 · see citing works