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A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron mouse)

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Effects of an Igf1 Gene Null Mutation on Mouse Reproduction

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Distinct and Overlapping Functions of Insulin and IGF-I Receptors

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Deletion, But Not Antagonism, of the Mouse Growth Hormone Receptor Results in Severely Decreased Body Weights, Insulin, and Insulin-Like Growth Factor I Levels and Increased Life Span

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Preputial Separation as an External Sign of Pubertal Development in the Male Rat1

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The Testis in Normal and Infertile Men.

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Tissue Distribution of Insulin-Like Growth Factor I and II Messenger Ribonucleic Acid in the Adult Rat*

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The hypothalamic-pituitary-adrenal axis and the female reproductive system

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Insulin-like growth factor I of peripheral origin acts centrally to accelerate the initiation of female puberty

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Effects of Exogenous Bovine Somatotropin on Lactation

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Gonadotropins and Estradiol Stimulate Immunoreactive Insulin-Like Growth Factor-I Production by Porcine Granulosa Cells in Vitro*

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Inherited Ateliotic Dwarfism in Mice: Characteristics of the mutation, little, on Chromosome 6

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Prolactin, Growth Hormone, and Luteinizing Hormone in the Maintenance of Testicular Luteinizing Hormone Receptors*

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Prolactin, Growth Hormone, and Epidermal Growth Factor Activate Stat5 in Different Compartments of Mammary Tissue and Exert Different and Overlapping Developmental Effects

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Growth hormone: roles in female reproduction

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Insulin-Like Growth Factor I: A Possible Metabolic Signal Involved in the Regulation of Female Puberty

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Characterization of Insulin and Insulin-Like Growth Factor I Receptors of Purified Leydig Cells and Their Role in Steroidogenesis in Primary Culture: A Comparative Study*

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Prolactin, Growth Hormone, Luteinizing Hormone Receptors, and Seasonal Changes in Testicular Activity in the Golden Hamster*

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Cellular Localization of the Growth Hormone Receptor/ Binding Protein in the Male and Female Reproductive Systems*

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Clinical review 75: Recent advances in pathogenesis, diagnosis, and management of acromegaly

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Partial correction of murine hereditary growth disorder by germ-line incorporation of a new gene

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Regulation of ovarian folliculogenesis by IGF and BMP system in domestic animals

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Growth Hormone Is Required for Ovarian Follicular Growth

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Can Growth Hormone (GH) Accelerate Aging? Evidence from GH-Transgenic Mice

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Immunoreactive sites and accumulation of somatomedin-C in rat Sertoli-spermatogenic cell co-cultures

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Growth Hormone Enhances Follicle-Stimulating Hormone-Induced Differentiation of Cultured Rat Granulosa Cells*

Jia, X., Kalmijn, J. A., & Hsueh, A. J. W. (1986) · Endocrinology · doi:10.1210/endo-118-4-1401 · Cited by 177 · see citing works

The physiology of folliculogenesis: the role of novel growth factors

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Reduced Levels of Thyroid Hormones, Insulin, and Glucose, and Lower Body Core Temperature in the Growth Hormone Receptor/Binding Protein Knockout Mouse

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Growth hormone deficiency in 'little' mice results in aberrant body composition, reduced insulin-like growth factor-I and insulin-like growth factor-binding protein-3 (IGFBP-3), but does not affect IGFBP-2, -1 or -4

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The Insulin‐like Growth Factor System: a Key Determinant Role in the Growth and Selection of Ovarian Follicles? A Comparative Species Study

Mazerbourg, S., Bondy, C., Zhou, J., & Monget, P. (2003) · Reproduction in Domestic Animals · doi:10.1046/j.1439-0531.2003.00440.x · Cited by 167 · see citing works

Cotreatment with human growth hormone and gonadotropins for induction of ovulation: a controlled clinical trial

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Pituitary and Testicular Function in Growth Hormone Receptor Gene Knockout Mice

Chandrashekar, V., Bartke, A., Coschigano, K. T., & Kopchick, J. J. (1999) · Endocrinology · doi:10.1210/endo.140.3.6557 · Cited by 163 · see citing works

Deficits in Female Reproductive Function in GH-R-KO Mice; Role of IGF-I

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Independent control of the production of insulin-like growth factor I and its binding protein by cultured testicular cells

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Insulin-like growth factor-1 (IGF-I) and IGF-I receptor in human testis: an immunohistochemical study

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Tissue Distribution, Characterization, and Regulation of Messenger Ribonucleic Acid for Growth Hormone Receptor and Serum Binding Protein in the Rat*

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Consequences of growth hormone (GH) overexpression and GH resistance

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Transgenic mouse models for studying the functions of insulin‐like growth factor‐binding proteins

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Identification of Insulin-Like Growth Factor I in Bovine Seminal Plasma and Its Receptor on Spermatozoa: Influence on Sperm Motility1

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Liver-Specific Expression of Human Insulin-Like Growth Factor Binding Protein-1 in Transgenic Mice: Repercussions on Reproduction, Ante- and Perinatal Mortality and Postnatal Growth1

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GH as a co-gonadotropin: the relevance of correlative changes in GH secretion and reproductive state

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Growth hormone: a reproductive endocrine-paracrine regulator?

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Selective Alterations in Organ Sizes in Mice with a Targeted Disruption of the Insulin-Like Growth Factor Binding Protein-2 Gene

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Puberty in Laron type dwarfism

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Activation of Growth Hormone Short Loop Negative Feedback Delays Puberty in the Female Rat*

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Possible role of growth hormone, IGFs, and IGF-binding proteins in the regulation of ovarian function in large farm animals

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GROWTH HORMONES AND SEX STEROID INTERACTIONS AT PUBERTY

Clark, P. A., & Rogol, A. D. (1996) · Endocrinology and Metabolism Clinics of North America · doi:10.1016/s0889-8529(05)70346-7 · Cited by 113 · see citing works

The IGF family and folliculogenesis

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PITUITARY CONTROL OF THE TESTIS OF THE HYPOPHYSECTOMIZED RAT1

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Induction of Endogenous Insulin-Like Growth Factor-I Secretion Alters the Hypothalamic-Pituitary-Testicular Function in Growth Hormone-Deficient Adult Dwarf Mice1

Chandrashekar, V., & Bartke, A. (1993) · Biology of Reproduction · doi:10.1095/biolreprod48.3.544 · Cited by 108 · see citing works

Delayed Aging in Ames Dwarf Mice. Relationships to Endocrine Function and Body Size

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Effect of insulin-like growth factor-I treatment on serum androgens and testicular and penile size in males with Laron syndrome (primary growth hormone resistance)

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Effects of Insulin-Like Growth Factor I on Steroidogenic Enzyme Expression Levels in Mouse Leydig Cells

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Neuroendocrine and Reproductive Consequences of Overexpression of Growth Hormone in Transgenic Mice

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Central effects of the somatotropic system

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Penis and testicular size in patients with growth hormone insufficency.

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The essential role of IGF-I: lessons from the long-term study and treatment of children and adults with Laron syndrome

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Growth Hormone and Insulin-Like Growth Factor I Treatment Increase Testicular Luteinizing Hormone Receptors and Steroidogenic Responsiveness of Growth Hormone Deficient Dwarf Mice*

CHATELAIN, P. G., Sánchez, P., & Saez, J. M. (1991) · Endocrinology · doi:10.1210/endo-128-4-1857 · Cited by 94 · see citing works

Role of Astroglia and Insulin-Like Growth Factor-I in Gonadal Hormone-Dependent Synaptic Plasticity

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Role of IGF-I in normal mammary development

Kleinberg, D. L. (1998) · Breast Cancer Research and Treatment · doi:10.1023/a:1005998832636 · Cited by 94 · see citing works

Growth Hormone Regulates Steroidogenic Acute Regulatory Protein Expression and Steroidogenesis in Leydig Cell Progenitors

Kanzaki, M., & Morris, P. L. (1999) · Endocrinology · doi:10.1210/endo.140.4.6661 · Cited by 93 · see citing works

Growth Hormone Cells as Co-gonadotropes: Partners in the Regulation of the Reproductive System

Childs, G. V. (2000) · Trends in Endocrinology and Metabolism · doi:10.1016/s1043-2760(00)00252-6 · Cited by 93 · see citing works

Insulin-Like Growth Factor I in the Developing and Mature Rat Testis: Immunohistochemical Aspects

Hansson, H., Billig, H., & Isgaard, J. (1989) · Biology of Reproduction · doi:10.1095/biolreprod40.6.1321 · Cited by 92 · see citing works

Cells that express luteinizing hormone (LH) and follicle-stimulating hormone (FSH) beta-subunit messenger ribonucleic acids during the estrous cycle: the major contributors contain LH beta, FSH beta, and/or growth hormone

Childs, G. V., Unabia, G. C., & ROUGEAU, D. (1994) · Endocrinology · doi:10.1210/endo.134.2.8299592 · Cited by 91 · see citing works

Delay of Puberty Onset in Females due to Suppression of Growth Hormone*

Ramaley, J. A., & Phares, C. K. (1980) · Endocrinology · doi:10.1210/endo-106-6-1989 · Cited by 89 · see citing works

Effects of Growth Hormone Overexpression and Growth Hormone Resistance on Neuroendocrine and Reproductive Functions in Transgenic and Knock‐Out Mice2

Bartke, A., Chandrashekar, V., Turyn, D., Steger, R. W., Debéljuk, L., Winters, T. A., Mattison, J. A., Danilovich, N., Croson, W., Wernsing, D. R., et al. (1999) · Proceedings of The Society for Experimental Biology and Medicine · doi:10.1046/j.1525-1373.1999.d01-121.x · Cited by 88 · see citing works

Insulin-like growth factor family in Graafian follicle development and function*1

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Insulin-like growth factor-I augments gonadotropin-stimulated androgen biosynthesis by cultured rat testicular cells

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Insulin-Like Growth Factor Binding Protein-3 Secretion from Cultured Rat Sertoli Cells: Dual Regulation by Follicle Stimulating Hormone and Insulin-Like Growth Factor-I

Smith, E. P., Dickson, B. A., & Chernausek, S. D. (1990) · Endocrinology · doi:10.1210/endo-127-6-2744 · Cited by 82 · see citing works

Impact of Growth Hormone Resistance on Female Reproductive Function: New Insights from Growth Hormone Receptor Knockout Mice1

Zaczek, D., Hammond, J. M., Suen, L., Wandji, S., Service, D., Bartke, A., Chandrashekar, V., Coschigano, K. T., & Kopchick, J. J. (2002) · Biology of Reproduction · doi:10.1095/biolreprod67.4.1115 · Cited by 82 · see citing works

Puberty Is Delayed in Male Growth Hormone Receptor Gene—Disrupted Mice

KEENE, D. E., Suescun, M. O., BOSTWICK, M. G., Chandrashekar, V., Bartke, A., & Kopchick, J. J. (2002) · Journal of Andrology · doi:10.1002/j.1939-4640.2002.tb02308.x · Cited by 75 · see citing works

Pubertal development and testicular function in the male growth hormone-deficient rat

Bartlett, J. M. S., Charlton, H. M., Robinson, I. C. A. F., & Nieschlag, E. (1990) · Journal of Endocrinology · doi:10.1677/joe.0.1260193 · Cited by 73 · see citing works

Anatomy of the insulin-like growth factor system in the human testis

Zhou, J., & Bondy, C. A. (1993) · Fertility and Sterility · doi:10.1016/s0015-0282(16)56294-3 · Cited by 72 · see citing works

Differential Expression of Growth Hormone Messenger Ribonucleic Acid by Somatotropes and Gonadotropes in Male and Cycling Female Rats

Childs, G. V., Unabia, G. C., & Wu, P. (2000) · Endocrinology · doi:10.1210/endo.141.4.7429 · Cited by 70 · see citing works

Cotreatment with growth hormone for induction of spermatogenesis in patients with hypogonadotropic hypogonadism

Shoham, Z., Conway, G. S., Ostergaard, H., Lahlou, N., Bouchard, P., & Jacobs, H. S. (1992) · Fertility and Sterility · doi:10.1016/s0015-0282(16)55023-7 · Cited by 70 · see citing works

The insulin-like growth factor (IGF) system and gonadotropin regulation: actions and interactions

Lackey, B. R., Gray, S. L., & Henricks, D. M. (1999) · Cytokine & Growth Factor Reviews · doi:10.1016/s1359-6101(99)00013-1 · Cited by 68 · see citing works

Endogenous Human Growth Hormone (GH) Modulates the Effect of Gonadotropin-Releasing Hormone on Pituitary Function and the Gonadotropin Response to the Negative Feedback Effect of Testosterone in Adult Male Transgenic Mice Bearing Human GH Gene*

Chandrashekar, V., Bartke, A., & Wagner, T. E. (1988) · Endocrinology · doi:10.1210/endo-123-6-2717 · Cited by 68 · see citing works

Control of production of insulin-like growth factor I by pig Leydig and Sertoli cells cultured alone or together. Cell-cell interactions

Naville, D., Chatelain, P., Avallet, O., & Saez, J. M. (1990) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(90)90212-q · Cited by 67 · see citing works

Identification and cellular localization of growth hormone receptor gene expression in the human ovary.

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Cytochemical detection of gonadotropin-releasing hormone-binding sites on rat pituitary cells with luteinizing hormone, follicle-stimulating hormone, and growth hormone antigens during diestrous up-regulation.

Childs, G. V., Unabia, G. C., & Miller, B. T. (1994) · Endocrinology · doi:10.1210/endo.134.4.8137763 · Cited by 67 · see citing works

Regulation of insulin-like growth factor-I messenger ribonucleic acid expression in Leydig cells

Lin, T., Wang, D., CALKINS, J. H., GUO, H., Chi, R., & Housley, P. R. (1990) · Molecular and Cellular Endocrinology · doi:10.1016/0303-7207(90)90127-t · Cited by 65 · see citing works

The Effect of Growth Hormone on the Leydig Cell Response to Chorionic Gonadotrophin in Boys With Hypopituitarism

KULIN, H. E., SAMOJLIK, E., SANTEN, R., & SANTNER, S. (1981) · Clinical Endocrinology · doi:10.1111/j.1365-2265.1981.tb00689.x · Cited by 65 · see citing works

Growth Hormone Insensitivity (Laron Syndrome)

Laron, Z. (2002) · Reviews in Endocrine and Metabolic Disorders · doi:10.1023/a:1020905725012 · Cited by 64 · see citing works

Growth Hormone (GH) Deprivation Induced by Passive Immunization against Rat GH-Releasing Factor Delays Sexual Maturation in the Male Rat*

Arsenijévic, Y., Wehrenberg, W. B., Conz, A., Eshkol, A., Sizonenko, P. C., & Aubert, M. L. (1989) · Endocrinology · doi:10.1210/endo-124-6-3050 · Cited by 62 · see citing works

Characterization and regulation of somatomedin‐C/insulin‐like growth factor I (Sm‐C/IGF‐I) receptors on cultured pig Leydig cells

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