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Cited by 258

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

Exercise during pregnancy and risk of gestational hypertensive disorders: a systematic review and meta‐analysis

Open access
Magro‐Malosso, Elena R., Saccone, Gabriele, Di Tommaso, Mariarosaria, Roman, Amanda, Berghella, Vincenzo·2017·Acta Obstetricia et Gynecologica Scandinavica

Abstract

Introduction: Gestational hypertensive disorders, including gestational hypertension and preeclampsia, are one of the leading causes of maternal morbidity and mortality. The aim of our study was to evaluate the effect of exercise during pregnancy on the risk of gestational hypertensive disorders. Material and methods: Electronic databases were searched from their inception to February 2017. Selection criteria included only randomized controlled trials of uncomplicated pregnant women assigned before 23 weeks to an aerobic exercise regimen or not. The summary measures were reported as relative risk with 95% confidence intervals. The primary outcome was the incidence of gestational hypertensive disorders, defined as either gestational hypertension or preeclampsia. Results: Seventeen trials, including 5075 pregnant women, were analyzed. Of them, seven contributed data to quantitative meta‐analysis for the primary outcome. Women who were randomized in early pregnancy to aerobic exercise for about 30–60 min two to seven times per week had a significant lower incidence of gestational hypertensive disorders (5.9% vs. 8.5%; relative risk 0.70, 95% confidence interval 0.53–0.83; seven studies, 2517 participants), specifically a lower incidence of gestational hypertension (2.5% vs. 4.6%; relative risk 0.54, 95% confidence interval 0.40–0.74; 16 studies, 4641 participants) compared with controls. The incidence of preeclampsia (2.3% vs. 2.8%; relative risk 0.79, 95% confidence interval 0.45–1.38; six studies, 2230 participants) was similar in both groups. The incidence of cesarean delivery was decreased by 16% in the exercise group. Conclusions: Aerobic exercise for about 30–60 min two to seven times per week during pregnancy, as compared with being more sedentary, is associated with a significantly reduced risk of gestational hypertensive disorders overall, gestational hypertension, and cesarean delivery.

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Metadata

Authors
Magro‐Malosso, E. R., Saccone, G., Di Tommaso, M., Roman, A., & Berghella, V.
Venue
Acta Obstetricia et Gynecologica Scandinavica
Publisher
Wiley
Published
2017-05-19
Volume
96
Issue
8
Pages
921-931
ISSN
  • 0001-6349 (ISSN-L)
  • 1600-0412
OpenAlex
W2605560929
Cited by
258
References
28
FWCI
4.01
Type
journal article
Language
en
Open access
bronze

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