Cited by 60

The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.

Effect of early probiotic supplementation on childhood cognition, behaviour and mood a randomised, placebo‐controlled trial

Slykerman, R F, Kang, J, Van Zyl, N, Barthow, C, Wickens, K, Stanley, T, Coomarasamy, C, Purdie, G, Murphy, R, Crane, J, Mitchell, E A·2018·Acta Paediatrica

Abstract

Aim: To determine whether probiotic supplementation in early life improves neurocognitive outcomes assessed at 11 years of age. Methods: A total of 474 children who were born March 2004–Aug 2005 participated in a two‐centre randomised placebo‐controlled trial of infants at risk of developing allergic disease. Pregnant women were randomised to take Lactobacillus rhamnosus strain HN001, Bifidobacterium animalis subsp. lactis strain HN019 or placebo daily from 35 weeks gestation until six months if breastfeeding, and their infants the same treatment from birth to two years. Intelligence, executive function, attention, depression and anxiety were assessed when the children were 11 years of age. Results: A total of 342 (72.2%) children were assessed (HN001 n = 109, HN019 n = 118 and placebo n = 115). Overall, there were no significant differences in the neurocognitive outcomes between the treatment groups. Conclusion: HN001 and HN019 given in early life were not associated with neurocognitive outcomes at 11 years of age in this study. However, we cannot exclude that other probiotics may have a beneficial effect. Further clinical trials are indicated.

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Crossref · 10.1111/apa.14590

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Research works printed but not linked: 22

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Metadata

Authors
Slykerman, R. F., Kang, J., Van Zyl, N., Barthow, C., Wickens, K., Stanley, T., Coomarasamy, C., Purdie, G., Murphy, R., Crane, J., & Mitchell, E. A.
Affiliations
  • Department of Psychological Medicine University of Auckland Auckland New Zealand
  • Department of Medicine University of Otago Wellington New Zealand
  • Department of Paediatrics: Child and Youth Health University of Auckland Auckland New Zealand
  • Department of Paediatrics University of Otago Wellington New Zealand
  • Dean's Office University of Otago Wellington New Zealand
  • Department of Medicine University of Auckland Auckland New Zealand
Venue
Acta Paediatrica
Publisher
Wiley
Published
2018-10-22
Volume
107
Issue
12
Pages
2172-2178
ISSN
  • 0803-5253
  • 1651-2227
Cited by
60
References
8
Language
en
Funders
  • Cure Kids
  • Fonterra Co-operative Group

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CoChat. (2026). Citation check: Effect of early probiotic supplementation on childhood cognition, behaviour and mood a randomised, placebo‐controlled trial. https://app.cochat.ai/papers/10.1111/apa.14590
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Slykerman, R. F., Kang, J., Van Zyl, N., Barthow, C., Wickens, K., Stanley, T., Coomarasamy, C., Purdie, G., Murphy, R., Crane, J., & Mitchell, E. A. (2018). Effect of early probiotic supplementation on childhood cognition, behaviour and mood a randomised, placebo‐controlled trial. Acta Paediatrica. https://doi.org/10.1111/apa.14590