Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression

Menke, A., Klengel, T., Rubel, J., Brückl, T., Pfister, H., Lucae, S., Uhr, M., Holsboer, F., Binder, E. B.·2013·Genes, Brain and Behavior
DOI 10.1111/gbb.12026

Cited by (151)

Items 101–151 of 151

  1. The Role of HSP90 Molecular Chaperones in Depression: Potential Mechanisms
    Xuyuan Fan, Lei Sun, Ye Qin, Yuan Liu, Shusheng Wu, Longfei Du · 2024 · Molecular Neurobiology
  2. The Association of Neighborhood Gene-Environment Susceptibility with Cortisol and Blood Pressure in African-American Adults
    Sandra M. Coulon, Dawn K. Wilson, M. L. Van Horn, Gregory A. Hand, Stephen Kresovich · 2015 · Annals of Behavioral Medicine
  3. The role of stress in absenteeism: cortisol responsiveness among patients on long-term sick leave
    Jacobsen, Henrik B., Bjørngaard, Johan Håkon, Hara, Karen W., Borchgrevink, Petter C., Woodhouse, Astrid, Landrø, Nils Inge, Harris, Anette, Stiles, Tore C. · 2014 · PLoS ONE
  4. Molecular evidence of altered stress responsivity related to neuroinflammation in the schizophrenia midbrain
    Sophie R. Debs, Debora A. Rothmond, Yunting Zhu, Cynthia Shannon Weickert, Tertia D. Purves-Tyson · 2024 · Journal of Psychiatric Research
  5. Monitoring candidate gene expression variations before, during and after a first major depressive episode in a 51-year-old man
    Raoul Belzeaux-R, Jean‐Michel Azorin, El Chérif Ibrahim · 2014 · BMC Psychiatry
  6. The association of FKBP5 polymorphism with asthma susceptibility in asthmatic patients
    Sura Fouad Alsaffar, Haider Abdulhameed Alqaraghuli, Jabbar H. Yenzeel, Haider Faisal Ghazi · 2021 · Journal of Basic and Clinical Physiology and Pharmacology
  7. Potential inhibitors for FKBP51: an in silico study using virtual screening, molecular docking and molecular dynamics simulation
    Sagar Barge, Dhananjay Jade, Selvaraj Ayyamperumal, Prasenjit Manna, Jagat Chandra Borah, Chandrasekar Moola Joghee Nanjan, Moola Joghee Nanjan, Narayan Chandra Talukdar · 2021 · Journal of Biomolecular Structure and Dynamics
  8. Longitudinal Monitoring of the Serotonin Transporter Gene Expression to Assess Major Depressive Episode Evolution
    Raoul Belzeaux-R, Anderson Loundou, Jean‐Michel Azorin, Jean Naudin, El Chérif Ibrahim · 2014 · Neuropsychobiology
  9. The role of childhood trauma, HPA axis reactivity and FKBP5 genotype on cognition in healthy individuals
    Álex Ferrer, Virginia Soria, Neus Salvat‐Pujol, Lourdes Martorell, Antonio Armario, Mikel Urretavizcaya, Alfonso Gutiérrez‐Zotes, José Antonio Monreal, José Manuel Crespo, Clara Massaneda‐Tuneu et al. · 2021 · Psychoneuroendocrinology
  10. Génétique de la dépression
    Nicolás Ramoz, Philip A. P. M. Gorwood · 2014 · Encyclopédie médico-chirurgicale. Psychiatrie
  11. Human myeloid progenitor glucocorticoid receptor activation causes genomic instability, type 1 IFN ‐ response pathway activation and senescence in differentiated microglia; an early life stress model
    Jingzhang Wei, Charles Arber, Selina Wray, John Hardy, Thomas M. Piers, Jennifer M. Pocock · 2022 · Glia
  12. Transcriptional evidence of HPA axis dysregulation in adolescent females: Unique contributions of chronic early-life stressor exposure and maternal depression history
    Summer Mengelkoch, Jenna C. Alley, Steve W. Cole, George M. Slavich · 2024 · Journal of Affective Disorders
  13. What future for neuroendocrinology in psychiatry?
    Fabrice Duval, Marie‐Claude Mokrani, Marc‐Antoine Crocq · 2013 · Psychoneuroendocrinology
  14. Genetic association of FKBP5 with trait resilience in Korean male patients with alcohol use disorder
    Chun Il Park, Hae Won Kim, Syung Shick Hwang, Jee In Kang, Se Joo Kim · 2021 · Scientific Reports
  15. Molecular biomarkers in depression: Toward personalized psychiatric treatment
    Anand Gururajan, John F. Cryan, Timothy G. Dinan · 2019 · Elsevier eBooks
  16. Effects of antidepressant on FKBP51 mRNA expression and neuroendocrine hormones in patients with panic disorder
    Zou, Zhili, Huang, Yulan, Maes, Michael, Wang, Jinyu, He, Ying, Min, Wenjiao, Zhou, Bo · 2024 · BMC Psychiatry
  17. Manipulation of a social signal affects DNA methylation of a stress-related gene in a free-living bird
    Sabrina M. McNew, Conor Claverie Taff, Maren N. Vitousek · 2024 · Journal of Experimental Biology
  18. Shared Genetic Architecture Among Severe Mental Disorders: A System Biology Approach Based on Protein–Protein Interaction
    Hernan Felipe Guillen-Burgos, Valentina Vanegas, Isabella Gonzalez, Ana M. Caicedo, Valentina Arango, Juan Francisco Galvez-Florez, Juan‐Manuel Anaya, Roger S. McIntyre, Wilson Terán · 2025 · Brain and Behavior
  19. FKBP51 functions in the regulation of circadian rhythm and Alzheimer's disease
    Jill L. Johnson · 2025 · Cell Stress and Chaperones
  20. Genetic variants in the glucocorticoid pathway genes and birth weight
    Michael Oliver Schneider, Theresa Hübner, Jutta Pretscher, Tamme Weyert Goecke, Judith Schwitulla, Lothar Häberle, Johannes Kornhuber, Arif Bülent Ekici, Matthias W. Beckmann, Peter Andreas Fasching et al. · 2020 · Archives of Gynecology and Obstetrics
  21. Expression of FKBP prolyl isomerase 5 gene in tissues of muscovy duck at different growth stages and its association with muscovy duck weight
    Zhigang Hu, Liyan Ge, Huilin Zhang, Xiaolin Liu · 2021 · Animal Bioscience
  22. Obtaining novel data‐driven hypotheses from teaching activities: An example assessing the role of the FKBP5 gene in major depression
    Heather Strelevitz, Alireza A. Dehaqani, Luigi Balasco, Yuri Bozzi · 2023 · European Journal of Neuroscience
  23. The Genetics of Impulsivity: A Synthesis of Findings in Humans and Rodent Models
    Bianca Jupp, Jeffrey W. Dalley · 2016 · Springer eBooks
  24. HPA-axis multilocus genetic interaction with stress life events in predicting changes in adolescent suicidal ideation
    Xian Zhao, Dongfang Wang, Mengmeng Chang, Zhen Jiang He, Zihao Zeng, Menghao Ren, Yiqiu Hu, Zhihua Li · 2025 · Journal of Affective Disorders
  25. Response to fluoxetine in children and adolescents: a weighted gene co-expression network analysis of peripheral blood.
    Teresa Torres, Daniel Boloc, Natàlia Rodríguez, Ana Blázquez, María Teresa Plana, Eva Varela, Patricia Gassó, Albert Martínez-Pinteño, Luisa Lázaro, Joan Albert Arnáiz et al. · 2020 · PubMed Central
  26. RETRACTED ARTICLE: Functional modular networks identify the pivotal genes associated with morphine addiction and potential drug therapies
    Yage Jiang, Donglei Wei, Yubo Xie · 2023 · BMC Anesthesiology · Retracted
  27. Association Study of the Heat Shock Protein 90 Alpha (HSP90AA1) Gene Polymorphisms with Schizophrenia in a Polish Population
    Małgorzata Kowalczyk, Aleksander Jerzy Owczarek, Krzysztof Artur Kucia, Maja Hasterok, Renata Suchanek-Raif, Monika Paul-Samojedny, Weronika Lakomy, Jan Kowalski · 2025 · Genes
  28. Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice
    Joeri Bordes, Xinna Ji, Serena Gasperoni, C. Sudre-Chinsky, AmirAli Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya V. Narayan, Manfred Uhr et al. · 2026 · Advanced Science
  29. Expression of genes in the brain associated with depression
    Н. Н. Дыгало, M. Yu. Stepanichev, Natalia V. Gulyaeva, Galina T. Shishkina · 2015 · Russian Journal of Genetics Applied Research
  30. Nuclear Receptor Coactivators
    Ioannis Zalachoras, Onno Cornelis Meijer · 2016 · Epigenetics and human health
  31. Circulating FK506 binding protein 51 mRNA expression in patients with pituitary adenomas
    Yingying Yang, Lilit Babayan, Argishty Mirzakhanian, Nvard Sisliyan, Dongyun Zhang, Carolina Hurtado, Abdul Zahid, Marvin Bergsneider, Won Bae Kim, Marilene B. Wang et al. · 2023 · Heliyon
  32. Early-life stress exposure and epigenetic programming
    Chloe M. Farrell · 2023 · Elsevier eBooks
  33. The Effects of HPA Axis Genetic Variation and Early Life Stress on Cortisol Levels in Preschool Age Children and on Amygdala and Hippocampus Volumes, Reactivity, and Connectivity at School Age
    David Pagliaccio · 2015 · Open Scholarship Institutional Repository (Washington University in St. Louis)
  34. Associations of psychiatric disease and aging on FKBP5 expression converge on cortical supragranular neurons
    Natalie Matosin, Janine Arloth, Darina Czamara, Katrina Z. Edmond, Malosree Maitra, Anna Sophie Fröhlich, Silvia Martinelli, Dominic Kaul, Rachael Bartlett, Amber R. Curry et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  35. Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity-Induced Social Deficits
    Joeri Bordes, Xinna Ji, Serena Gasperoni, Choham Sudre-Chinsky, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya V. Narayan, Manfred Uhr, Christian Namendorf et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  36. Interaction of Polymorphisms in the FKBP5 Gene & Childhood Adversity on the Cortisol Response to a Psychosocial Stress Task in Adolescents and Young Adults
    Raegan Mazurka · 2013
  37. Complementation of Pharmacogenetics with Biomarkers and Neuroimaging in Major Depression
    Andreas Menke, Nicola Dusi, Paolo Brambilla · 2016 · Springer eBooks
  38. Epigenetic & transcriptomic alterations associated with childhood maltreatment, major depressive disorder, and post-traumatic stress disorder
    Angela C. Bustamante · 2017 · Illinois Digital Environment for Access to Learning and Scholarship (University of Illinois at Urbana-Champaign)
  39. Corticolimbic Circuitry and Genomic Risk for Stress-Related Psychopathology
    Sarah E. Paul, Nourhan M. Elsayed, Erin Bondy, Ryan Bogdan · 2020 · Elsevier eBooks
  40. Association of Stress, Glucocorticoid Receptor, and FK506 Binding Protein Gene Polymorphisms With Internalizing Disorders Among HIV-Infected Children and Adolescents From Kampala and Masaka Districts—Uganda
    Tonny Jimmy Owalla, Wilber Joseph Ssebajjwe, Dennis Muhanguzi, Jacqueline Samantha Womersley, Eugene Kinyanda, Allan Kalungi · 2021 · Frontiers in Pediatrics
  41. FKBP5 Epialleles
    Torsten Klengel, Theo Rein · 2016 · Epigenetics and human health
  42. References
    2015 · Elsevier eBooks
  43. A BIOECOLOGICAL APPROACH TO UNDERSTANDING THE INTERACTION OF ENVIRONMENTAL STRESS AND GENETIC SUSCEPTIBILITY IN INFLUENCING CORTISOL AND BLOOD PRESSURE IN AFRICAN AMERICAN ADULTS
    Sandra M. Coulon · 2014 · Scholar Commons (University of South Carolina)
  44. Additional file 1 of Effects of antidepressant on FKBP51 mRNA expression and neuroendocrine hormones in patients with panic disorder
    Zou, Zhili, Huang, Yulan, Maes, Michael, Jinyu Wang, Ying He, Min, Wenjiao, Bo Zhou · 2024 · Figshare
  45. Additional file 1 of FKBP51 mediates resilience to inflammation-induced anxiety through regulation of glutamic acid decarboxylase 65 expression in mouse hippocampus
    Gan, Yu-Ling, Wang, Chen-Yu, He, Rong-Heng, Hsu, Pei-Chien, Yeh, Hsin-Hsien, Hsieh, Tsung-Han, Lin, Hui-Ching, Cheng, Ming-Yen, Jeng, Chung-Jiuan, Huang, Ming-Chyi et al. · 2022 · Figshare
  46. Additional file 2 of Effects of antidepressant on FKBP51 mRNA expression and neuroendocrine hormones in patients with panic disorder
    Zou, Zhili, Huang, Yulan, Maes, Michael, Jinyu Wang, Ying He, Wenjiao Min, Bo Zhou · 2024 · Figshare
  47. Immune-related biomarkers for major depressive disorder identified via integrated bioinformatics and machine learning
    Yu Zhang, Ping Wu, Zeng Nie, Zhuo Liu · 2026 · European Journal of Psychotraumatology
  48. FKBP5 splice variant alterations in the human cortex of psychiatric disorders
    Dominic Kaul, Katrina Z. Edmond, Darina Czamara, Silvia Martinelli, Maik Ködel, Nils C. Gassen, Ran Tao, Joel E. Kleinman, Thomas M. Hyde, Elisabeth B. Binder et al. · 2026 · Journal of Psychiatric Research
  49. Individualized pharmacogenomics for depressive episodes: A narrative review
    MICHEL HADDAD, Luiz Henrique Junqueira Dieckmann, Giovana Regina Weber Hoss, Jair de Jesus Mari, Allan Hunter Young, Mário F. Juruena · 2026 · Journal of Affective Disorders
  50. Change in FK506 binding protein 5 (FKBP5) methylation over time among preschoolers with adversity
    Parade, Stephanie H., Parent, Justin, Rabemananjara, Kantoniony, Seifer, Ronald, Marsit, Carmen J., Yang, Bao-Zhu, Zhang, Huiping, Tyrka, Audrey R. · 2017 · Development and Psychopathology
  51. Gene expression associated with PTSD in World Trade Center responders: An RNA sequencing study
    Kuan, Pei-Fen, Waszczuk, Monika A., Kotov, Roman, Clouston, Sean, Yang, Xiaohua, Singh, Prashant K., Glenn, Sean T., Cortes Gomez, Eduardo, Wang, Jianmin, Bromet, Evelyn et al. · 2017 · Translational Psychiatry