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Cited by 308Medication Adherence and CompliancePharmaceutical Practices and Patient OutcomesPharmacy and Medical Practices

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Systematic review of the barriers affecting medication adherence in older adults

Yap, Angela Frances, Thirumoorthy, Thiru, Kwan, Yu Heng·2016·Geriatrics & Gerontology International
DOI 10.1111/ggi.12616
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Abstract

Medication adherence is a crucial part in the management of chronic diseases. As older adults form a greater proportion of the population with chronic diseases and multiple morbidities, understanding medication adherence in older adults becomes important. In the present article, we aimed to systematically review the literature for the factors associated with medication adherence in the geriatric population. We carried out a literature search using electronic databases and related keywords. 17 391 articles were reviewed in total. 65 articles were found to be relevant to our objective. A total of 80 factors of five different categories were found to be associated with medication adherence in older adults. The factors, the types of studies and the number of studies that agreed or disagreed were presented. A flower model for medication adherence was also presented to allow clinicians to better understand the complex nature of medication adherence in this population. The 80 factors reviewed were categorized into five main categories; namely, patient factors, medication factors, physician factors, system-based factors and other factors as factors affecting poor medication adherence in older adults. Clinicians need to be mindful of the complex nature of factors affecting medication adherence in this population to optimize therapeutic outcomes. Clinicians have to be more skillful to discover and to optimize the medication adherence factors in geriatric patients. The flower model is p…

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Research works printed but not linked: 70

  1. 10.1186/1741-7015-12-3 · DOI
  2. 10.1080/08870446.2013.863884 · DOI
  3. 10.1517/14740338.2014.947260 · DOI
  4. 10.1016/j.amjopharm.2011.11.005 · DOI · Paper page
  5. 10.1016/j.pmedr.2014.10.001 · DOI
  6. 10.1016/j.jsps.2015.01.013 · DOI
  7. 10.1016/j.amjopharm.2011.02.004 · DOI
  8. 10.1007/s40266-014-0153-9 · DOI
  9. 10.1093/geront/gns006 · DOI
  10. 10.1111/j.1532-5415.1999.tb02988.x · DOI
  11. Yap AF, 2015, Medication adherence in the elderly, J Clin Gerontol Geriatr
  12. 10.1111/j.1447-0594.2012.00916.x · DOI
  13. 10.1016/S0002-9343(96)00172-6 · DOI
  14. 10.1331/JAPhA.2008.07040 · DOI
  15. 10.1046/j.1365-2648.1995.21050935.x · DOI
  16. 10.1007/s12160-010-9217-1 · DOI
  17. 10.2165/00129784-200808010-00006 · DOI
  18. 10.2165/00002512-200825100-00005 · DOI
  19. 10.1007/s11606-014-2956-0 · DOI
  20. 10.1016/j.cjca.2013.04.009 · DOI
  21. 10.1002/mds.21831 · DOI
  22. Morgan SG, 2004, Persistence with hypertension treatment among community‐dwelling BC seniors, Can J Clin Pharmacol, 11, e267
  23. 10.2165/00002512-200825100-00008 · DOI
  24. 10.1111/jgs.12171 · DOI
  25. 10.1046/j.1532-5415.2002.50205.x · DOI
  26. 10.1111/pme.12035 · DOI
  27. 10.1111/j.1532-5415.2009.02639.x · DOI
  28. 10.1177/1043659609360707 · DOI
  29. Lam PW, 2007, Drug non‐adherence and associated risk factors among Chinese geriatric patients in Hong Kong, Hong Kong Med J, 13, 284
  30. 10.1016/j.archger.2011.09.014 · DOI
  31. 10.1111/j.1442-2018.2011.00594.x · DOI
  32. 10.1007/s40266-012-0007-2 · DOI
  33. 10.1016/j.hrtlng.2014.05.001 · DOI
  34. 10.1093/ageing/aft083 · DOI
  35. 10.18553/jmcp.2014.20.1.58 · DOI
  36. 10.1177/0898264309332836 · DOI · Paper page
  37. 10.1007/BF00579707 · DOI
  38. 10.2165/11537320-000000000-00000 · DOI
  39. 10.1111/j.1524-4733.2009.00679.x · DOI
  40. 10.1111/j.1532-5415.2012.04239.x · DOI
  41. 10.1097/HPC.0b013e318230d423 · DOI
  42. 10.1097/00019442-200512000-00006 · DOI
  43. 10.1007/s00774-008-0007-9 · DOI
  44. 10.1080/03601277.2013.802186 · DOI
  45. 10.1016/j.pec.2010.05.006 · DOI
  46. Iversen MD, 2011, Factors affecting adherence to osteoporosis medications: a focus group approach examining viewpoints of patients and providers, J Geriatr Phys Ther, 34, 72
  47. 10.1093/geronb/61.2.P102 · DOI · Paper page
  48. 10.1016/j.amjopharm.2008.11.001 · DOI
  49. 10.1111/ggi.12042 · DOI
  50. 10.1007/s11096-013-9863-z · DOI
  51. 10.1007/s11606-011-1886-3 · DOI
  52. 10.1080/10810730.2012.712611 · DOI
  53. 10.1002/nur.4770140108 · DOI
  54. 10.1016/j.sapharm.2012.12.002 · DOI
  55. Kendrick R, 1982, Compliance with prescribed medication by elderly patients, Can Med Assoc J, 127, 961
  56. 10.1093/eurjhf/hfp059 · DOI
  57. 10.1002/pds.1766 · DOI
  58. 10.1111/j.1365-2702.2012.04144.x · DOI
  59. 10.1016/j.jpsychores.2010.07.014 · DOI
  60. 10.1007/s002280050358 · DOI
  61. 10.1097/01.JCN.0000287029.87746.58 · DOI
  62. 10.1071/HC13234 · DOI
  63. 10.1097/JGP.0b013e3181f1803d · DOI
  64. 10.1378/chest.09-3031 · DOI
  65. 10.1111/j.1547-5069.1991.tb00677.x · DOI
  66. 10.1016/j.amjopharm.2009.04.005 · DOI
  67. 10.2105/AJPH.83.5.711 · DOI
  68. 10.1136/emj.2008.058297 · DOI
  69. 10.1111/j.1369-7625.2005.00351.x · DOI
  70. 10.1016/j.socscimed.2014.11.010 · DOI

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Metadata

Authors
Yap, A. F., Thirumoorthy, T., & Kwan, Y. H.
Affiliations
Duke-NUS Medical School (SG)
Corresponding author
Kwan, Yu Heng
ORCID
Kwan, Yu Heng
Venue
Geriatrics & Gerontology International
Publisher
Wiley
Published
2015-10-20
Volume
16
Issue
10
Pages
1093-1101
ISSN
  • 1444-1586 (ISSN-L)
  • 1447-0594
DOI
10.1111/ggi.12616
OpenAlex
W2116716283
Cited by
308
References
0
Citations by year
2026: 20 · 2025: 25 · 2024: 35 · 2023: 40 · 2022: 63 · 2021: 41 · 2020: 24 · 2019: 22 · 2018: 23 · 2017: 11 · 2016: 3
FWCI
2.05
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Geriatrics and gerontology international/Geriatrics & gerontology international (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
  • Health Sciences › Medicine › Geriatrics and Gerontology › Pharmaceutical Practices and Patient Outcomes
  • Health Sciences › Health Professions › Pharmacy › Pharmacy and Medical Practices
Keywords
medication adherence, older adults, barriers to adherence, chronic disease management, patient factors, physician characteristics, elderly patients
MeSH terms
Aged, Aged, 80 and over, Chronic Disease, Cognition Disorders, Dementia, Humans, Socioeconomic Factors, Geriatric Assessment, Incidence, Drug Monitoring, Risk Assessment, Needs Assessment, Medication Adherence

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