Clinical, biochemical and ultrasonographic characteristics of Scandinavian women with PCOS
Abstract
Background. The aim was to investigate the clinical, biochemical and ultrasonographic characteristics of Scandinavian women with polycystic ovarian syndrome (PCOS), and to see whether there were any differences between eumenorrhoic and oligoamenorrhoic women. Methods. Eighty women aged between 18 and 40 years with PCOS were investigated in a prospective study. The inclusion criteria were polycystic ovaries (PCO), body mass index (BMI) >25 kg/m 2 and at least one of the following: testosterone >2.5 nmol/L, sex hormone binding globulin (SHBG) <30 nmol/L, fasting C‐peptide >1.0 nmol/L, oligoamenorrhea or hirsutism. Results. Eumenorrhoic and oligoamenorrhoic women with PCOS did not differ in age, age at menarche, blood pressure, BMI, free testosterone index (FTI), insulin C‐peptide or fasting glucose. A thicker endometrium and a smaller ovarian volume were found in eumenorrhoic compared to oligoamenorrhoic patients. There was linear association between BMI and the number of diagnostic criteria met. Conclusion. BMI was associated with the severity of the PCOS. There were no differences in basic clinical and biochemical parameters between eumenorrhoic and oligoamenorrhoic patients with PCOS.
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Typically, baseline values of women with PCOS included in this review were below recommended cut-offs for diagnosing hyperandrogenism (testosterone >2.5 nmol/L and SHBG <30 nmol/L), indicating that they were not markedly hyperandrogenic.
“Typically, the baseline values of women with PCOS included in this current review were below recommended cut-offs for diagnosing hyperandrogenism; testosterone > 2.5 nmol/L and SHBG < 30 nmol/L [152], which indicates that they were not markedly hyperandrogenic.”
From Exercise, or exercise and diet for the management of polycystic ovary syndrome: a systematic review and meta-analysis (2019) · cites this paper as [152]
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- Authors
- Vanky, E., Kjøtrød, S., Salvesen, K. Å., Romundstad, P., Moen, M. H., & Carlsen, S. M.
- Affiliations
- St Olav's University Hospital (NO)
- Corresponding author
- Vanky, Eszter
- Venue
- Acta Obstetricia et Gynecologica Scandinavica
- Publisher
- Wiley
- Published
- 2004-04
- Volume
- 83
- Issue
- 5
- Pages
- 482-486
- ISSN
- 0001-6349 (ISSN-L)
- 1600-0412
- OpenAlex
- W2136073465
- Cited by
- 26
- References
- 24
- Citations by year
- 2024: 1 · 2023: 1 · 2022: 2 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 1 · 2013: 2 · 2012: 1
- FWCI
- 2.58
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Obstetricia Et Gynecologica Scandinavica (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Keywords
- polycystic ovary syndrome, eumenorrhea, oligoamenorrhea, body mass index, endometrial thickness, ovarian volume, free testosterone index, insulin resistance, sex hormone-binding globulin, hirsutism, age at menarche
- MeSH terms
- Adult, C-Peptide, Endometrium, Female, Humans, Medical Records, Menstruation, Norway, Ovary, Polycystic Ovary Syndrome, Retrospective Studies, Risk Factors, Sex Hormone-Binding Globulin, Testosterone, Ultrasonography, Body Mass Index
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