Does disulfiram have a role in alcoholism treatment today?
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The psychological or cognitive threat of a DER is thought to be dominant and active and thus dissuade use.
“To prevent the first drink, however, the psychological or cognitive threat is thought to be dominant and active and thus dissuade use [5], [6], [7].”
From Disulfiram Efficacy in the Treatment of Alcohol Dependence: A Meta-Analysis (2014) · cites this paper as [5]
Disulfiram's mechanism of action for maintaining alcohol abstinence is thought to be primarily psychological.
“Its mechanism of action for maintaining alcohol abstinence is thought to be primarily psychological [4], [5], [6], [7] and based on a highly disagreeable pharmacological effect if alcohol is consumed.”
From Disulfiram Efficacy in the Treatment of Alcohol Dependence: A Meta-Analysis (2014) · cites this paper as [5]
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“Its mechanism of action for maintaining alcohol abstinence is thought to be primarily psychological [4,5,6,7] and based on a highly disagreeable pharmacological effect if alcohol is consumed.”
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- Authors
- FULLER, R. K., & GORDIS, E.
- Venue
- Addiction
- Publisher
- Wiley
- Published
- 2003-12-17
- Volume
- 99
- Issue
- 1
- Pages
- 21-24
- ISSN
- 0965-2140 (ISSN-L)
- 1360-0443
- OpenAlex
- W1990492557
- Cited by
- 182
- References
- 25
- Citations by year
- 2026: 4 · 2025: 4 · 2024: 1 · 2023: 7 · 2022: 6 · 2021: 3 · 2020: 5 · 2019: 8 · 2018: 6 · 2017: 7 · 2016: 5 · 2015: 5 · 2014: 9 · 2013: 10 · 2012: 5
- FWCI
- 7.48
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Addiction (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
- Keywords
- disulfiram, alcoholism treatment, alcoholism, pharmacotherapy
- MeSH terms
- Alcohol Deterrents, Alcoholism, Disulfiram, Drug Therapy, Combination, Humans, Treatment Outcome, Patient Selection
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