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Cited by 525

The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.

The co‐occurring use and misuse of cannabis and tobacco: a review

Open access
Agrawal, Arpana, Budney, Alan J., Lynskey, Michael T.·2012·Addiction

Abstract

Aims Cannabis and tobacco use and misuse frequently co‐occur. This review examines the epidemiological evidence supporting the life‐time co‐occurrence of cannabis and tobacco use and outlines the mechanisms that link these drugs to each other. Mechanisms include (i) shared genetic factors; (ii) shared environmental influences, including (iii) route of administration (via smoking), (iv) co‐administration and (v) models of co‐use. We also discuss respiratory harms associated with co‐use of cannabis and tobacco, overlapping withdrawal syndromes and outline treatment implications for co‐occurring use. Methods Selective review of published studies. Results Both cannabis and tobacco use and misuse are influenced by genetic factors, and a proportion of these genetic factors influence both cannabis and tobacco use and misuse. Environmental factors such as availability play an important role, with economic models suggesting a complementary relationship where increases in price of one drug decrease the use of the other. Route of administration and smoking cues may contribute to their sustained use. Similar withdrawal syndromes, with many symptoms in common, may have important treatment implications. Emerging evidence suggests that dual abstinence may predict better cessation outcomes, yet empirically researched treatments tailored for co‐occurring use are lacking. Conclusions There is accumulating evidence that some mechanisms linking cannabis and tobacco use are distinct from those contributing to co‐occurring use of drugs in general. There is an urgent need for research to identify the underlying mechanisms and harness their potential etiological implications to tailor treatment options for this serious public health challenge.

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Crossref · 10.1111/j.1360-0443.2012.03837.x

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Metadata

Authors
Agrawal, A., Budney, A. J., & Lynskey, M. T.
Venue
Addiction
Publisher
Wiley
Published
2012-04-17
Volume
107
Issue
7
Pages
1221-1233
ISSN
  • 0965-2140 (ISSN-L)
  • 1360-0443
OpenAlex
W1796700544
Cited by
525
References
10
FWCI
13.96
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: The co‐occurring use and misuse of cannabis and tobacco: a review. https://app.cochat.ai/papers/10.1111/j.1360-0443.2012.03837.x
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Agrawal, A., Budney, A. J., & Lynskey, M. T. (2012). The co‐occurring use and misuse of cannabis and tobacco: a review. Addiction. https://doi.org/10.1111/j.1360-0443.2012.03837.x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.