CoChat
Sign Up
Cited by 113Gastrointestinal motility and disordersFood Allergy and Anaphylaxis ResearchCeliac Disease Research and Management

The DOI matches its Crossref record; 43 of the 44 references it cites were found in a registry or an index.

Alterations of food antigen‐specific serum immunoglobulins G and E antibodies in patients with irritable bowel syndrome and functional dyspepsia

Zuo, X. L., Li, Y. Q., Li, W. J., Guo, Y. T., Lu, X. F., Li, J. M., Desmond, P. V.·2007·Clinical & Experimental Allergy
DOI 10.1111/j.1365-2222.2007.02727.x
Open this paper in CoChat — free account

Abstract

Summary: Background Post‐prandial worsening of symptoms as well as adverse reactions to one or more foods are common in the patients with functional gastrointestinal diseases, such as irritable bowel syndrome (IBS) and functional dyspepsia (FD). However, the role played by true food allergy in the pathogenesis of these diseases is still controversial and there are no well‐established tests to identify food allergy in this condition. Objective To investigate serum food antigen‐specific IgG, IgE antibody and total IgE antibody titres in controls and patients with IBS and FD, and to correlate symptoms with the food antigen‐specific IgG titres in IBS and FD patients. Methods Thirty‐seven IBS patients, 28 FD patients and 20 healthy controls participated in this study. Serum IgG and IgE antibody titres to 14 common foods including beef, chicken, codfish, corn, crab, eggs, mushroom, milk, pork, rice, shrimp, soybean, tomatoes and wheat were analysed by ELISA. Serum total IgE titres were also measured. Last, symptomatology was assessed in the study. Results IBS patients had significantly higher titres of IgG antibody to crab (P=0.000), egg (P=0.000), shrimp (P=0.000), soybean (P=0.017) and wheat (P=0.004) than controls. FD patients had significantly higher titres of IgG antibody to egg (P=0.000) and soybean (P=0.017) than controls. The percentage of individuals with detectable positive food antigen‐specific IgE antibodies of the three groups did not show any significant differences (P=0.971). There were no significant differences between IBS patients, FD patients and controls in the serum total IgE antibody titres (P=0.978). Lastly, no significant correlation was seen between symptom severity and serum food antigen‐specific IgG antibody titres both in IBS and FD patients. Conclusion Serum IgG antibody titres to some common foods increased in IBS and FD patients compared to controls. But there is no significant correlation between symptom severity and elevated serum food antigen‐specific IgG antibodies in these patients.

Overview

Integrity signals

Registry

Crossref · 10.1111/j.1365-2222.2007.02727.x

Cites

43 of 43 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Research works printed but not linked: 3

  1. Roudebush P., 1995, Kirk's current veterinary therapy XII, 59
  2. 10.1111/j.1572-0241.1999.01226.x · DOI
  3. 10.1111/j.1572-0241.1998.00531.x · DOI

Cited by

Sorted by citations

See all 113

Related

See all

Metadata

Authors
Zuo, X. L., Li, Y. Q., Li, W. J., Guo, Y. T., Lu, X. F., Li, J. M., & Desmond, P. V.
Affiliations
  • Shandong University (CN)
  • St Vincent's Hospital Melbourne (AU)
Corresponding author
  • Li, Y. Q.
  • Li, J. M.
ORCID
Venue
Clinical & Experimental Allergy
Publisher
Wiley
Published
2007-05-17
Volume
37
Issue
6
Pages
823-830
ISSN
  • 0954-7894 (ISSN-L)
  • 1365-2222
DOI
10.1111/j.1365-2222.2007.02727.x
OpenAlex
W1986358628
Cited by
113
References
44
Citations by year
2026: 2 · 2025: 7 · 2024: 1 · 2023: 1 · 2022: 5 · 2021: 7 · 2020: 4 · 2019: 5 · 2018: 10 · 2017: 4 · 2016: 3 · 2015: 4 · 2014: 12 · 2013: 11 · 2012: 6
FWCI
8.70
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Clinical & Experimental Allergy (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Natural Science Foundation of China
  • Natural Science Foundation of Shandong Province
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Health Sciences › Medicine › Immunology and Allergy › Food Allergy and Anaphylaxis Research
  • Health Sciences › Medicine › Gastroenterology › Celiac Disease Research and Management
Keywords
irritable bowel syndrome, functional dyspepsia, food allergy, total IgE, serum antibody titres, symptom severity, crabs, eggs, soybean, wheat
MeSH terms
Adult, Antibody Specificity, Antigens, Dyspepsia, Female, Food Hypersensitivity, Humans, Immunoglobulin E, Immunoglobulin G, Male, Severity of Illness Index, Irritable Bowel Syndrome

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review