CoChat
Sign Up
Cited by 117Thyroid Disorders and TreatmentsBlood Pressure and Hypertension StudiesThyroid and Parathyroid Surgery

The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.

Subclinical thyroid dysfunction and blood pressure: a community‐based study

Walsh, John P., Bremner, Alexandra P., Bulsara, Max K., O’Leary, Peter, Leedman, Peter J., Feddema, Peter, Michelangeli, Valdo·2006·Clinical Endocrinology
DOI 10.1111/j.1365-2265.2006.02619.x
Open this paper in CoChat — free account

Abstract

Objective Overt hypothyroidism and hyperthyroidism are associated with hypertension, but it is uncertain whether the same is true of subclinical hypothyroidism and hyperthyroidism. Design, subjects and measurements Cross‐sectional study of 2033 participants (aged 17–89 years) in the Busselton Thyroid Study who did not have a history of thyroid disease. Systolic blood pressure (SBP), diastolic blood pressure (DBP) and the prevalence of hypertension (defined as SBP 140 mmHg, DBP 90 mmHg or on treatment for hypertension) in subjects with thyroid dysfunction and euthyroid subjects were compared using linear regression models. Subjects with treated hypertension (N = 299) were excluded from analyses of SBP and DBP but included in analyses of hypertension prevalence. Results Mean SBP, DBP and the prevalence of hypertension did not differ significantly between subjects with subclinical hypothyroidism (N = 105) and euthyroid subjects (N = 1859), nor did they differ between subjects with serum TSH concentrations in the upper reference range (2·0–4·0 mU/l; N = 418) and those with TSH concentrations in the lower reference range (0·4–2·0 mU/l; N = 1441). The prevalence of hypertension was higher in subjects with subclinical hyperthyroidism than euthyroid subjects (prevalence odds ratio 2·8, 95% confidence interval 1·3–6·0 adjusted for age, age 2 and sex), but this was based on a small number of subjects with subclinical hyperthyroidism (N = 35). Conclusions Subclinical hypothyroidism is not associated with hypertension. The observed association between subclinical hyperthyroidism and hypertension requires confirmation in a larger sample.

Overview

Integrity signals

Registry

Crossref · 10.1111/j.1365-2265.2006.02619.x

Cites

40 of 40 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Flagged first, then by citations

Show all 39 references

Research works printed but not linked: 1

  1. Knudsen N., 2005, Elevated blood pressure is associated with small differences in TSH in a general population, Thyroid, 15, S

Cited by

Sorted by citations

Items 101–116 of 116

Related

See all

Metadata

Authors
Walsh, J. P., Bremner, A. P., Bulsara, M. K., O’Leary, P., Leedman, P. J., Feddema, P., & Michelangeli, V.
Affiliations
The University of Western Australia (AU)
Corresponding author
Walsh, John P.
ORCID
Venue
Clinical Endocrinology
Publisher
Wiley
Published
2006-09-05
Volume
65
Issue
4
Pages
486-491
ISSN
  • 0300-0664 (ISSN-L)
  • 1365-2265
DOI
10.1111/j.1365-2265.2006.02619.x
OpenAlex
W1989249037
Cited by
117
References
39
Citations by year
2024: 3 · 2023: 6 · 2022: 9 · 2021: 2 · 2020: 7 · 2019: 4 · 2018: 5 · 2017: 3 · 2016: 9 · 2015: 6 · 2014: 6 · 2013: 10 · 2012: 6
FWCI
4.98
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Clinical Endocrinology (publishedVersion)
  • PubMed (publishedVersion)
  • UWA Profiles and Research Repository (UWA) (submittedVersion)
Funders
Merck Sharp and Dohme
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
  • Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
Keywords
subclinical hypothyroidism, subclinical hyperthyroidism, hypertension, blood pressure, thyroid-stimulating hormone, thyroid dysfunction
MeSH terms
Adolescent, Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Diastole, Female, Health Surveys, Humans, Hypertension, Hyperthyroidism, Hypothyroidism, Male, Middle Aged, Risk, Systole, Thyroid Diseases, Thyrotropin, Thyroxine, Western Australia, Odds Ratio

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review