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Cited by 75Thyroid Disorders and TreatmentsThyroid and Parathyroid SurgeryThyroid Cancer Diagnosis and Treatment

Is a more active attitude warranted in patients with subclinical thyrotoxicosis

TENERZ, Å., FORBERG, R., JANSSON, R.·1990·Journal of Internal Medicine
DOI 10.1111/j.1365-2796.1990.tb00223.x
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Abstract

In 1985 one of the new sensitive thyroid stimulating hormone (TSH) assays was introduced as part of our laboratory routine for thyroid function testing. Consequently, we now routinely identify a small but not insignificant group of patients with 'subclinical thyrotoxicosis', i.e. a low serum TSH in conjunction with a normal serum free T4. We here present the results of a 2-year follow-up investigation, which includes 40 patients with subclinical thyrotoxicosis and 40 euthyroid control patients. The group with subclinical thyrotoxicosis was characterized by a mean age of 65 years and a high prevalence of nodular goitre. Twelve (30%) of the patients but none of the individuals in the control group were treated during the follow-up period because of clinical thyroid disease. Atrial fibrillation was found in 11 (28%) patients compared to four (10%) of the controls. Therapy should be considered more often than previously in patients with nodular goitre and subclinical thyrotoxicosis, particularly in conjunction with atrial fibrillation.

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Crossref · 10.1111/j.1365-2796.1990.tb00223.x

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  • Older patients with low TSH and higher fT4 have a higher prevalence and incidence of atrial fibrillation compared with euthyroid subjects.

    “Older patients with low TSH and higher fT4 have a higher prevalence and incidence of atrial fibrillation compared with euthyroid subjects (94–98)”

    From Levothyroxine therapy in elderly patients with hypothyroidism (2021) · cites this paper as [96]

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Authors
TENERZ, Å., FORBERG, R., & JANSSON, R.
Affiliations
Västerås Municipality (SE)
Corresponding author
TENERZ, Å.
Venue
Journal of Internal Medicine
Publisher
Wiley
Published
1990-09
Volume
228
Issue
3
Pages
229-233
ISSN
  • 0954-6820 (ISSN-L)
  • 1365-2796
DOI
10.1111/j.1365-2796.1990.tb00223.x
OpenAlex
W2008199023
Cited by
75
References
15
Citations by year
2024: 1 · 2022: 1 · 2021: 3 · 2017: 3 · 2015: 1 · 2014: 1 · 2013: 3 · 2012: 2
FWCI
0.95
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 6912 d)
Locations
  • Journal of Internal Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
  • Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
Keywords
subclinical thyrotoxicosis, low TSH, nodular goiter, atrial fibrillation, thyroid function tests, follow-up, antithyroid drug therapy
MeSH terms
Aged, Alkaline Phosphatase, Atrial Fibrillation, Attitude of Health Personnel, Female, Follow-Up Studies, Goiter, Graves Disease, Humans, Male, Thyroid Function Tests, Thyroiditis, Autoimmune, Thyrotoxicosis, Thyrotropin, Osteocalcin, Incidence

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