Low‐intensity endurance exercise training, plasma lipoproteins and the risk of coronary heart disease
Abstract
Physically active individuals generally show a reduced risk of coronary heart disease (CHD) compared to the sedentary population. However, whether such reduction in CHD risk mainly results from the concomitant improvement in cardiorespiratory fitness or from the alterations in CHD risk factors has yet to be clearly established. Furthermore, there is still some controversy regarding the potential associations between endurance training-induced changes in metabolic variables considered as CHD risk factors (plasma glucose, insulin and lipoprotein levels) and the magnitude of improvement in cardiorespiratory fitness. From the results of several studies discussed in this article, it is proposed that prolonged endurance exercise of low intensity (approximately 50% VO2max), performed on an almost daily basis, seems to significantly improve metabolic variables considered as CHD risk factors through mechanisms that are likely to be independent from the training-related changes in cardiorespiratory fitness. The notion of 'metabolic fitness' is introduced and can be defined as the state of a ste of metabolic variables relevant to CHD risk and affected by the level of physical activity. Evidence available suggests that these metabolic variables are not closely related to the adaptation of cardiorespiratory fitness in response to exercise training. The concept of metabolic fitness has several implications for the prescription of exercise and for the primary and secondary prevention of CHD…
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Regular endurance exercise training has been shown to mobilize body fat, assist with weight loss, and alter body composition such as reducing abdominal adipose tissue in patients with hypertriglyceridemia.
“Regular endurance exercise training has been shown to mobilize body fat, assist with weight loss, and alter body composition such as reducing abdominal adipose tissue in patients with hypertriglyceridemia, all of which may lead to improvements in carbohydrate and lipid metabolism (61,101).”
From 2021 ACC Expert Consensus Decision Pathway on the Management of ASCVD Risk Reduction in Patients With Persistent Hypertriglyceridemia (2021) · cites this paper as [101]
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- Authors
- Després, J., & LAMARCHE, B.
- Affiliations
- Université Laval (CA)
- Venue
- Journal of Internal Medicine
- Publisher
- Wiley
- Published
- 1994-07
- Volume
- 236
- Issue
- 1
- Pages
- 7-22
- ISSN
- 0954-6820 (ISSN-L)
- 1365-2796
- OpenAlex
- W2011551225
- Cited by
- 164
- References
- 7
- Citations by year
- 2026: 1 · 2023: 2 · 2021: 3 · 2019: 1 · 2018: 3 · 2017: 3 · 2016: 2 · 2015: 4 · 2014: 2 · 2013: 3 · 2012: 2
- FWCI
- 4.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Keywords
- coronary heart disease risk, serum lipoproteins, metabolic fitness, cardiorespiratory fitness, exercise prescription, daily walking, insulin, plasma glucose, lipid metabolism, weight loss, cardiovascular risk factors
- MeSH terms
- Adult, Analysis of Variance, Coronary Disease, Humans, Insulin Resistance, Lipoproteins, Male, Physical Fitness, Reference Values, Risk Factors, Exercise
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