Cited by 2,955Birth, Development, and HealthPrenatal Substance Exposure EffectsPregnancy and preeclampsia studies

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The origins of the developmental origins theory

Barker, D. J. P.·2007·Journal of Internal Medicine

DOI 10.1111/j.1365-2796.2007.01809.x

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Abstract

Current orthodoxy states that coronary heart disease results from the unhealthy lifestyles of westernized adults together with a contribution from genetic inheritance. This does not provide a secure basis for prevention of the disease. Geographical studies gave the first clue that the disease originates during intra-uterine development. Variations in mortality from the disease across England and Wales were shown to correlate closely with past differences in death rates among newborn babies. In the past most deaths among newborns were attributed to low birthweight. This led to the hypothesis that undernutrition in utero permanently changes the body's structure, function and metabolism in ways that lead to coronary heart disease in later life. The association between low birthweight and coronary heart disease has been confirmed in longitudinal studies of men and women around the world. The developmental model of the origins of the disease offers a new way forward.

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Sick individuals and sick populations
Rose, G. (2001) · International Journal of Epidemiology · doi:10.1093/ije/30.3.427 · Cited by 3,736
WEIGHT IN INFANCY AND DEATH FROM ISCHAEMIC HEART DISEASE
Barker, D. J. P., Osmond, C., Winter, P. D., Margetts, B., & Simmonds, S. J. (1989) · The Lancet · doi:10.1016/s0140-6736(89)90710-1 · Cited by 3,574
Self-citation
Fetal origins of coronary heart disease
Barker, D. J. P. (1995) · BMJ · doi:10.1136/bmj.311.6998.171 · Cited by 3,570
Self-citation
INFANT MORTALITY, CHILDHOOD NUTRITION, AND ISCHAEMIC HEART DISEASE IN ENGLAND AND WALES
BARKER, D. (1986) · The Lancet · doi:10.1016/s0140-6736(86)91340-1 · Cited by 2,892
Self-citation
Sick individuals and sick populations
ROSE, G. (1985) · International Journal of Epidemiology · doi:10.1093/ije/14.1.32 · Cited by 2,701
Phenotypic Plasticity and the Origins of Diversity
West-Eberhard, M. J. (1989) · Annual Review of Ecology and Systematics · doi:10.1146/annurev.es.20.110189.001341 · Cited by 2,110
Trajectories of growth among children who have coronary events as adults
Barker, D. J. P., Osmond, C., Forsén, T. J., Kajantie, E., & Eriksson, J. G. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa044160 · Cited by 1,517
Self-citation
INEQUALITIES IN DEATH—SPECIFIC EXPLANATIONS OF A GENERAL PATTERN?
Marmot, M. G., Shipley, M. J., & Rose, G. (1984) · The Lancet · doi:10.1016/s0140-6736(84)92337-7 · Cited by 1,461
Primary Prevention of Ischemic Stroke
Goldstein, L. B., Adams, R. J., Alberts, M. J., Appel, L. J., Brass, L. M., Bushnell, C., Culebras, A., DeGraba, T. J., Gorelick, P. B., Guyton, J. R., et al. (2006) · Stroke · doi:10.1161/01.str.0000223048.70103.f1 · Cited by 1,376
Seven Countries
Keys, A. B. (1980) · Harvard University Press eBooks · doi:10.4159/harvard.9780674497887 · Cited by 908

Show all 39 references

Research works printed but not linked: 5

Registrar General, Registrar General's Statistical Review of England and Wales. Part 1. Tables, Medical
Office of Population Censuses and Surveys, 1978, Registrar General's Decennial Supplement, Occupational Mortality, England and Wales 1970–72
Notkola V., 1985, Living Conditions in Childhood and Coronary Heart Disease in Adulthood
Local Government Board, 1910, Thirty‐ninth Annual Report 1909–10. Supplement on Infant and Child Mortality
10.1136/bmj.315.7105.396 · DOI

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Wang, Q., Kurita, H., Carreira, V., Ko, C., Fan, Y., Zhang, X., Biesiada, J., Medvedovic, M., & Puga, A. (2015) · Toxicological Sciences · doi:10.1093/toxsci/kfv246 · Cited by 59
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Guo, J., Wu, C., Zhang, J., Li, W., Lv, S., Lu, D., Qi, X., Feng, C., Liang, W., Chang, X., et al. (2020) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.140678 · Cited by 59
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Velazquez, M. A., Sheth, B., Smith, S. J., Eckert, J. J., Osmond, C., & Fleming, T. P. (2017) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2017.11.020 · Cited by 58
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Donovan, L. E., & Cundy, T. (2015) · Diabetic Medicine · doi:10.1111/dme.12625 · Cited by 57
Criteria for placental examination for obstetrical and neonatal providers
Roberts, D. J., Baergen, R. N., Boyd, T. K., Carreon, C. K., Duncan, V. E., Ernst, L. M., Faye-Petersen, O. M., Folkins, A. K., Hecht, J. L., Heerema‐McKenney, A., et al. (2022) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2022.12.017 · Cited by 57
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Authors: Barker, D. J. P.
Affiliations: Oregon Health & Science University (US)
Corresponding author: Barker, D. J. P.
Venue: Journal of Internal Medicine
Publisher: Wiley
Published: 2007-04-10
Volume: 261
Issue: 5
Pages: 412-417
ISSN: 0954-6820 (ISSN-L)
1365-2796
DOI: 10.1111/j.1365-2796.2007.01809.x
OpenAlex: W2143847855
Cited by: 2,955
References: 39
Citations by year: 2026: 174 · 2025: 216 · 2024: 219 · 2023: 263 · 2022: 258 · 2021: 247 · 2020: 209 · 2019: 165 · 2018: 170 · 2017: 160 · 2016: 135 · 2015: 123 · 2014: 103 · 2013: 99 · 2012: 115
FWCI: 10.12
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Journal of Internal Medicine (publishedVersion)
PubMed (publishedVersion)
ePrints Soton (University of Southampton) (submittedVersion)
Topics: Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Prenatal Substance Exposure Effects
Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
Keywords: coronary artery disease, developmental origins of health and disease, low birth weight, intrauterine undernutrition, fetal origins of disease, coronary heart disease prevention
MeSH terms: Adult, Coronary Disease, England, Female, Humans, Infant Mortality, Infant, Low Birth Weight, Infant, Newborn, Life Style, Male, Pregnancy, Prenatal Exposure Delayed Effects, Social Conditions, Wales, Fetal Development, Fetal Nutrition Disorders

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