Smoking and the outcome of infection: Review: Smoking and infection
Abstract
Abstract. Huttunen R, Heikkinen T, Syrjänen J. (Department of Internal Medicine, Tampere University Hospital, Tampere; Department of Pediatrics, Turku University Hospital, Turku; Finland) Smoking and the Outcome of Infection (Review). J Intern Med 2010; 269: 258–269. Smoking has substantial local and systemic adverse effects on the immune system, respiratory tract and skin and soft tissues. Smokers are at increased risk of invasive pneumococcal disease, pneumonia, periodontitis, surgical infections, tuberculosis, influenza and meningococcal disease. The results of several studies indicate that smokers with periodontitis or tuberculosis suffer more severe disease. Data on the impact of smoking on sepsis and pneumonia are controversial and limited, and systematic data regarding the outcome of the majority of infections in smokers are scarce. Abundant data indicate that children exposed to environmental tobacco smoke (ETS) suffer from more severe infections. However, information regarding the effects of ETS on the outcome of infections in adults is limited. Various aspects of the relation between smoking and the outcome of bacterial infection (e.g. potential dose-dependent effects and the interactions between smoking and other environmental factors that may affect the course of infectious diseases) remain to be established.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Smokers are at greater risk of infection.
“Several researchers agree that smokers are at greater risk of infection [48,49].”
From Skeletal System Biology and Smoke Damage: From Basic Science to Medical Clinic (2021) · cites this paper as [48]
Cites
Mandell, L. A., Wunderink, R. G., Anzueto, A., Bartlett, J. G., Campbell, G. D., Dean, N. C., Dowell, S. F., File, T. M., Musher, D. M., Niederman, M. S., et al. (2007) · Clinical Infectious Diseases · doi:10.1086/511159 · Cited by 6,182 · see citing works
Mortality in relation to smoking : 40 years' observations on male British doctors
Doll, H. (1994) · Medical Entomology and Zoology · Cited by 1,417 · see citing works
Mortality in relation to smoking: 40 years' observations on male British doctors
Doll, R., Peto, R., Wheatley, K., Gray, R., & Sutherland, I. (1994) · BMJ · doi:10.1136/bmj.309.6959.901 · Cited by 1,321 · see citing works
Prognosis and Outcomes of Patients With Community-Acquired Pneumonia
Fine, M. J. (1996) · JAMA · doi:10.1001/jama.1996.03530260048030 · Cited by 1,309 · see citing works
Effects of cigarette smoke on the immune system
Sopori, M. L. (2002) · Nature reviews. Immunology · doi:10.1038/nri803 · Cited by 1,219 · see citing works
Mortality in relation to consumption of alcohol: 13 years' observations on male British doctors
Doll, R., Peto, R., Hall, E., Wheatley, K., & Gray, R. G. (1994) · BMJ · doi:10.1136/bmj.309.6959.911 · Cited by 1,179 · see citing works
Møller, A. M., Villebro, N., Pedersen, T., & Tønnesen, H. (2002) · The Lancet · doi:10.1016/s0140-6736(02)07369-5 · Cited by 1,109 · see citing works
Cigarette Smoking and Infection
Arcavi, L., & Benowitz, N. L. (2004) · Archives of Internal Medicine · doi:10.1001/archinte.164.20.2206 · Cited by 1,020 · see citing works
Prenatal and postnatal environmental tobacco smoke exposure and children's health.
Difranza, J., Aligne, C., & Weitzman, M. (2004) · Pediatrics · doi:10.1542/peds.113.s3.1007 · Cited by 806 · see citing works
Cigarette Smoking and Invasive Pneumococcal Disease
Nuorti, J. P., Butler, J. C., Farley, M. M., Harrison, L. H., McGeer, A., KOLCZAK, M. S., & Breiman, R. F. (2000) · New England Journal of Medicine · doi:10.1056/nejm200003093421002 · Cited by 796 · see citing works
Tobacco Smoke, Indoor Air Pollution and Tuberculosis: A Systematic Review and Meta-Analysis
Lin, H.-H., Ezzati, M., & Murray, M. B. (2007) · PLoS Medicine · doi:10.1371/journal.pmed.0040020 · Cited by 740 · see citing works
Assessment of Risk for Periodontal Disease. II. Risk Indicators for Alveolar Bone Loss
Grossi, S. G., Genco, R. J., Machtet, E. E., Ho, A. W., Koch, G. G., Dunford, R. G., Zambon, J. J., & Hausmann, E. (1995) · Journal of Periodontology · doi:10.1902/jop.1995.66.1.23 · Cited by 735 · see citing works
The health consequences of involuntary smoking : a report of the Surgeon General
Education. Office on Smoking (1986) · Medical Entomology and Zoology · Cited by 687 · see citing works
How cigarette smoke skews immune responses to promote infection, lung disease and cancer
Stämpfli, M. R., & Anderson, G. P. (2009) · Nature reviews. Immunology · doi:10.1038/nri2530 · Cited by 668 · see citing works
Bacterial Pneumonia in Persons Infected with the Human Immunodeficiency Virus
Hirschtick, R. E., Glassroth, J. L., Jordan, M. C., Wilcosky, T. C., Wallace, J. M., Kvale, P. A., Markowitz, N. P., Rosen, M. J., Mangura, B. T., & Hopewell, P. C. (1995) · New England Journal of Medicine · doi:10.1056/nejm199509283331305 · Cited by 609 · see citing works
Evidence for Cigarette Smoking as a Major Risk Factor for Periodontitis
Haber, J., Wattles, J., Crowley, M., Mandell, R. L., JOSHIPURA, K. J., & Kent, R. (1993) · Journal of Periodontology · doi:10.1902/jop.1993.64.1.16 · Cited by 602 · see citing works
Liu, B.-Q., Peto, R., Chen, Z. M., Boreham, J., Wu, Y., Li, J. Y., Campbell, T. C., & Chen, J.-S. (1998) · BMJ · doi:10.1136/bmj.317.7170.1411 · Cited by 570 · see citing works
Leandro, G., Mangia, A., Hui, J. M., Fabris, P., Rubbia‐Brandt, L., Colloredo, G., Adinolfi, L. E., Asselah, T., Jonsson, J. R., Smedile, A., et al. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.03.014 · Cited by 562 · see citing works
A Nationally Representative Case–Control Study of Smoking and Death in India
Jha, P., Jacob, B. J., Gajalakshmi, V., Gupta, P. C., Dhingra, N., Kumar, R., Sinha, D. N., Dikshit, R. P., Parida, D. K., Kamadod, R., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmsa0707719 · Cited by 554 · see citing works
Risk of Tuberculosis From Exposure to Tobacco Smoke
Bates, M. (2007) · Archives of Internal Medicine · doi:10.1001/archinte.167.4.335 · Cited by 553 · see citing works
Abstinence From Smoking Reduces Incisional Wound Infection: A Randomized Controlled Trial
Sorensen, L. T., Karlsmark, T., & Gottrup, F. (2003) · Annals of Surgery · doi:10.1097/01.sla.0000074980.39700.31 · Cited by 551 · see citing works
Incidence, organ dysfunction and mortality in severe sepsis: a Spanish multicentre study
Blanco, J., Muriel-Bombín, A., Sagredo-Meneses, V., Taboada, F., Gandía, F., Tamayo, L., Collado, J., García-Labattut, Á., Carriedo, D., Valledor, M., et al. (2008) · Critical Care · doi:10.1186/cc7157 · Cited by 519 · see citing works
Cigarette Smoking Decreases Tissue Oxygen
Jensen, J. A. (1991) · Archives of Surgery · doi:10.1001/archsurg.1991.01410330093013 · Cited by 517 · see citing works
Gajalakshmi, V., Peto, R., Kanaka, T. S., & Jha, P. (2003) · The Lancet · doi:10.1016/s0140-6736(03)14109-8 · Cited by 476 · see citing works
Early Wound Complications of Operative Treatment of Calcaneus Fractures: Analysis of 190 Fractures
Folk, J. W., Starr, A. J., & Early, J. S. (1999) · Journal of Orthopaedic Trauma · doi:10.1097/00005131-199906000-00008 · Cited by 406 · see citing works
Strachan, D. P., & Cook, D. G. (1997) · Thorax · doi:10.1136/thx.52.10.905 · Cited by 383 · see citing works
Tobacco smoking and chronic destructive periodontal disease
Bergstr�m, J. (2004) · Odontology · doi:10.1007/s10266-004-0043-4 · Cited by 369 · see citing works
A 10‐Year Prospective Study of Tobacco Smoking and Periodontal Health
Bergström, J., Eliasson, S., & Dock, J. (2000) · Journal of Periodontology · doi:10.1902/jop.2000.71.8.1338 · Cited by 363 · see citing works
INFANT ADMISSIONS TO HOSPITAL AND MATERNAL SMOKING
Harlap, S., & Davies, A. M. (1974) · The Lancet · doi:10.1016/s0140-6736(74)92714-7 · Cited by 349 · see citing works
Baik, I., Curhan, G. C., Rimm, E. B., Bendich, A., Willett, W. C., & Fawzi, W. W. (2000) · Archives of Internal Medicine · doi:10.1001/archinte.160.20.3082 · Cited by 346 · see citing works
Tobacco and tuberculosis: a qualitative systematic review and meta-analysis.
Slama, K., Chiang, C.-Y., Enarson, D. A., Hassmiller, K. M., Fanning, A., Gupta, P., & Ray, C. (2007) · PubMed · Cited by 339 · see citing works
Chapman, C. B. (1975) · The Lancet · doi:10.1016/s0140-6736(75)92882-2 · Cited by 338 · see citing works
Prognosis and outcomes of patients with community-acquired pneumonia. A meta-analysis
Fine, M. J. (1996) · JAMA · doi:10.1001/jama.275.2.134 · Cited by 337 · see citing works
Smoking and causes of death among U.S. veterans: 16 years of observation.
Rogot, E., & Jl, M. (1980) · PubMed · Cited by 329 · see citing works
Less collagen production in smokers
Jørgensen, L. N., Kallehave, F., Christensen, E., Siana, J. E., & Gottrup, F. (1998) · Surgery · doi:10.1016/s0039-6060(98)70167-9 · Cited by 322 · see citing works
Smoking vs Other Risk Factors as the Cause of Smoking-Attributable Deaths
Thun, M. J., Apicella, L. F., & Henley, S. J. (2000) · JAMA · doi:10.1001/jama.284.6.706 · Cited by 307 · see citing works
Bercault, N., & Boulain, T. (2001) · Critical Care Medicine · doi:10.1097/00003246-200112000-00012 · Cited by 304 · see citing works
Cirrhosis as a Risk Factor for Sepsis and Death
Foreman, M. G., Mannino, D. M., & Moss, M. (2003) · CHEST Journal · doi:10.1378/chest.124.3.1016 · Cited by 301 · see citing works
Yu, M., Hsu, F.-C., Sheen, I. S., Chu, C., Lin, D., Chen, C., & Liaw, Y. (1997) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a009060 · Cited by 289 · see citing works
Risk Factors for Tissue and Wound Complications in Gastrointestinal Surgery
Sørensen, L. T., Hemmingsen, U., Kallehave, F., Wille-Jørgensen, P., Kjærgaard, J., Møller, L. N., & Jørgensen, T. (2005) · Annals of Surgery · doi:10.1097/01.sla.0000157131.84130.12 · Cited by 285 · see citing works
Moss, M. M., Parsons, P. E., Steinberg, K. P., Hudson, L. D., Guidot, D. M., Burnham, E. L., Eaton, S., & Cotsonis, G. (2003) · Critical Care Medicine · doi:10.1097/01.ccm.0000055389.64497.11 · Cited by 278 · see citing works
Smoking as a risk factor for wound healing and infection in breast cancer surgery
Sørensen, L. T., Hørby, J., Friis, E., Pilsgaard, B., & Jørgensen, T. (2002) · European Journal of Surgical Oncology · doi:10.1053/ejso.2002.1308 · Cited by 276 · see citing works
Smoking and periodontal disease severity
Martínez‐Canut, P., Lorca, A., & Magán, R. (1995) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1995.tb00256.x · Cited by 275 · see citing works
Low natural killer‐cell activity and immunoglobulin levels associated with smoking in human subjects
Ferson, M. J., Edwards, A., Lind, A., Milton, G. W., & Hersey, P. (1979) · International Journal of Cancer · doi:10.1002/ijc.2910230504 · Cited by 271 · see citing works
Cigarette Smoking and Periodontal Bone Loss
Bergström, J., Eliasson, S., & Preber, H. (1991) · Journal of Periodontology · doi:10.1902/jop.1991.62.4.242 · Cited by 265 · see citing works
Hugh, A. E., & FOX, J. A. (1963) · The Lancet · doi:10.1016/s0140-6736(63)90357-x · Cited by 260 · see citing works
O’Brien, J. M., Lü, B., Ali, N. A., Martin, G. S., Aberegg, S. K., Marsh, C. B., Lemeshow, S. A., & Douglas, I. S. (2007) · Critical Care Medicine · doi:10.1097/01.ccm.0000254340.91644.b2 · Cited by 257 · see citing works
Feldman, J. G., Minkoff, H., Schneider, M. F., Gange, S. J., Cohen, M. H., Watts, D. H., Gandhi, M., Mocharnuk, R. S., & Anastos, K. (2006) · American Journal of Public Health · doi:10.2105/ajph.2005.062745 · Cited by 255 · see citing works
Exposure to tobacco smoking and periodontal health
Bergström, J., Eliasson, S., & Dock, J. (2000) · Journal Of Clinical Periodontology · doi:10.1034/j.1600-051x.2000.027001061.x · Cited by 250 · see citing works
Crothers, K. A., Griffith, T. A., McGinnis, K. A., Rodriguez‐Barradas, M. C., Leaf, D. A., Weissman, S., Gibert, C. L., Butt, A. A., & Justice, A. C. (2005) · Journal of General Internal Medicine · doi:10.1111/j.1525-1497.2005.0255.x · Cited by 248 · see citing works
Rosenstein, N. E., Emery, K. W., Werner, S. B., Kao, A., Johnson, R., Rogers, D., Vugia, D., Reingold, A., Talbot, R., Plikaytis, B. D., et al. (2001) · Clinical Infectious Diseases · doi:10.1086/319203 · Cited by 232 · see citing works
Houston, T. K., Person, S. D., Pletcher, M. J., Liu, K., Iribarren, C., & Kiefe, C. I. (2006) · BMJ · doi:10.1136/bmj.38779.584028.55 · Cited by 226 · see citing works
Co‐twin control study of the relationship between smoking and some periodontal disease factors
Bergström, J., & FLODERUS-MYRHED, B. (1983) · Community Dentistry And Oral Epidemiology · doi:10.1111/j.1600-0528.1983.tb01367.x · Cited by 216 · see citing works
Cigarette smoking and alveolar bone height in subjects with a high standard of oral hygiene
Bergström, J., & Eliasson, S. (1987) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1987.tb02253.x · Cited by 214 · see citing works
Tobacco smoke as a risk factor for meningococcal disease
Fischer, M., Hedberg, K., CARDOSI, P., Plikaytis, B. D., Hoesly, F. C., Steingart, K. R., BELL, T. A., Fleming, D., Wenger, J. D., & Perkins, B. A. (1997) · The Pediatric Infectious Disease Journal · doi:10.1097/00006454-199710000-00015 · Cited by 210 · see citing works
Cigarette Smoking and Hepatic Lesions in Patients With Chronic Hepatitis C
Pessione, F., Ramond, M.-J., Njapoum, C., Duchatelle, V., Degott, C., Erlinger, S., RUEFF, B., Valla, D. C., & Degos, F. (2001) · Hepatology · doi:10.1053/jhep.2001.25385 · Cited by 207 · see citing works
Mortality and smoking in Hong Kong: case-control study of all adult deaths in 1998
Lam, T., Ho, S. Y., Hedley, A. J., Mak, K. H., & Peto, R. (2001) · BMJ · doi:10.1136/bmj.323.7309.361 · Cited by 200 · see citing works
Cigarette Smoking as a Risk Factor for Epidemic A(H1N1) Influenza in Young Men
Kark, J. D., Lebiush, M., & RANNON, L. (1982) · New England Journal of Medicine · doi:10.1056/nejm198210213071702 · Cited by 197 · see citing works
Importance of pre-existing co-morbidities for prognosis of septicemia in critically ill patients
Pittet, D., Thiévent, B., Wenzel, R. P., Li, N., Gürman, G., & Suter, P. M. (1993) · Intensive Care Medicine · doi:10.1007/bf01690546 · Cited by 191 · see citing works
Effects of cigarette smoke on epithelial cells of the respiratory tract.
Dye, J. A., & Adler, K. B. (1994) · Thorax · doi:10.1136/thx.49.8.825 · Cited by 191 · see citing works
The Effects of Cigarette Smoking on T Cell Subsets: A Population-based Survey of Healthy Caucasians
Tollerud, D. J., Clark, J. W., Brown, L. M., et al. (1989) · American Review of Respiratory Disease · doi:10.1164/ajrccm/139.6.1446 · Cited by 189 · see citing works
LaCroix, A. Z., Lipson, S., Miles, T. P., & White, L. R. (1989) · Europe PMC (PubMed Central) · Cited by 188 · see citing works
Green, G. M., & Carolin, D. (1967) · New England Journal of Medicine · doi:10.1056/nejm196702232760801 · Cited by 188 · see citing works
Li, J. S. M., Peat, J. K., Xuan, W., & Berry, G. (1999) · Pediatric Pulmonology · doi:10.1002/(sici)1099-0496(199901)27:1 · Cited by 182 · see citing works
Kalin, M., Örtqvist, Å., Almela, M., et al. (2000) · The Journal of Infectious Diseases · doi:10.1086/315760 · Cited by 182 · see citing works
Apatzidou, D. A., Riggio, M. P., & Kinane, D. F. (2005) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.2005.00788.x · Cited by 179 · see citing works
Cigarette Smoking and Neoplasia of the Uterine Cervix: Smoke Constituents in Cervical Mucus
(1985) · New England Journal of Medicine · doi:10.1056/nejm198501313120516 · Cited by 172 · see citing works
Longitudinal study of prognostic factors in established periodontitis patients
Machtei, E. E., Dunford, R. G., Hausmann, E., Grossi, S. G., Powell, J. R., Cummins, D., Zambon, J. J., & Genco, R. J. (1997) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1997.tb00474.x · Cited by 171 · see citing works
Gwaltney, J. M. (1967) · JAMA · doi:10.1001/jama.202.6.494 · Cited by 166 · see citing works
Tobacco associated mortality in Mumbai (Bombay) India. Results of the Bombay Cohort Study
Gupta, P. C., Pednekar, M. S., Parkin, D. M., & Sankaranarayanan, R. (2005) · International Journal of Epidemiology · doi:10.1093/ije/dyi196 · Cited by 159 · see citing works
Smoking, the environment and meningococcal disease: a case control study
Stanwell, R. E., Stuart, J. M., Hughes, A., Robinson, P. M., Griffin, M., & Cartwright, K. A. V. (1994) · Epidemiology and Infection · doi:10.1017/s0950268800057733 · Cited by 156 · see citing works
Kaech, C., Elzi, L., Sendi, P., Frei, R., Laifer, G., Bassetti, S., & Flückiger, U. M. (2006) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2005.01359.x · Cited by 155 · see citing works
Effect of Cigarette Smoking on Periodontal Status of Healthy Young Adults
Machuca‐Portillo, G., Rosales, I., Lacalle-Remigio, J. R., et al. (2000) · Journal of Periodontology · doi:10.1902/jop.2000.71.1.73 · Cited by 154 · see citing works
Cigarette smoke worsens lung inflammation and impairs resolution of influenza infection in mice
Gualano, R. C., Hansen, M. J., Vlahos, R., Jones, J. E. C., Park-Jones, R. A., Deliyannis, G., Turner, S. J., Duca, K., & Anderson, G. P. (2008) · Respiratory Research · doi:10.1186/1465-9921-9-53 · Cited by 152 · see citing works
Risk of severe periodontal disease in a Swedish adult population
Norderyd, O. M., Hugoson, A., & Grusovin, G. M. (1999) · Journal Of Clinical Periodontology · doi:10.1034/j.1600-051x.1999.260908.x · Cited by 151 · see citing works
Katanoda, K., Marugame, T., Saika, K., Satoh, H., Tajima, K., Suzuki, T., Tamakoshi, A., Tsugane, S., & Sobue, T. (2008) · Journal of Epidemiology · doi:10.2188/jea.je2007429 · Cited by 148 · see citing works
Renvert, S., Dahlén, G., & Wikström, M. B. (1998) · Journal Of Clinical Periodontology · doi:10.1111/j.1600-051x.1998.tb02421.x · Cited by 148 · see citing works
Epidemiologic risk factors for periodontal attachment loss among adults in the United States
Hyman, J. J., & Reid, B. C. (2003) · Journal Of Clinical Periodontology · doi:10.1034/j.1600-051x.2003.00157.x · Cited by 146 · see citing works
Hanshaoworakul, W., Simmerman, J. M., Narueponjirakul, U., Sanasuttipun, W., Shinde, V., Kaewchana, S., Areechokechai, D., Levy, J., & Ungchusak, K. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006051 · Cited by 142 · see citing works
Tobacco attributable deaths in South Africa
Sitas, F., Urban, M. I., Bradshaw, D., Kielkowski, D., Bah, S. M., & Peto, R. (2004) · Tobacco Control · doi:10.1136/tc.2004.007682 · Cited by 137 · see citing works
EFFECT OF SMOKING ON MENINGOCOCCAL CARRIAGE
Stuart, J. M., Robinson, P., Cartwright, K. V., et al. (1989) · The Lancet · doi:10.1016/s0140-6736(89)90781-2 · Cited by 137 · see citing works
Pneumococcal pneumonia presenting with septic shock: host- and pathogen-related factors and outcomes
García‐Vidal, C., Ardanuy, C., Tubau, F., et al. (2009) · Thorax · doi:10.1136/thx.2009.123612 · Cited by 137 · see citing works
Woloshin, S., Schwartz, L. M., & Welch, H. G. (2008) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djn124 · Cited by 136 · see citing works
The effect of changed smoking habits on marginal alveolar bone loss. A longitudinal study.
Bolin, A., Eklund, G., Frithiof, L., & Lavstedt, S. (1993) · PubMed · Cited by 126 · see citing works
Influence of Comorbid Conditions on Long‐Term Mortality After Pneumonia in Older People
Yende, S. P., Angus, D. C., Ali, I. S., Somes, G. W., Newman, A. B., Bauer, D. C., Garcia, M. N., Harris, T. B., Kritchevsky, S. B., & Study, F. T. H. A. (2007) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2007.01100.x · Cited by 126 · see citing works
Impact of smoking on histological liver lesions in chronic hepatitis C
Hézode, C., Lonjon, I., Roudot‐Thoraval, F., Mavier, J.-P., Pawlotsky, J., Zafrani, E. S., & Dhumeaux, D. (2002) · Gut · doi:10.1136/gut.52.1.126 · Cited by 122 · see citing works
Factors impacting on length of stay and mortality of community-acquired pneumonia
Garau, J., Baquero, F., Pérez-Trallero, E., Pérez, J., Martín‐Sánchez, A. M., Garcı́a-Rey, C., Martín-Herrero, J. E., & Dal−Ré, R. (2008) · Clinical Microbiology and Infection · doi:10.1111/j.1469-0691.2007.01915.x · Cited by 119 · see citing works
Cigarette Smoking, Bacterial Pneumonia, and Other Clinical Outcomes in HIV-1 Infection
Burns, D. N., Hillman, D. R., Neaton, J. D., Sherer, R. D., Mitchell, T. F., Capps, L., Vallier, W. G., & Thurnherr, M. D. (1996) · Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology · doi:10.1097/00042560-199612010-00012 · Cited by 118 · see citing works
Fariñas, M. C., Peralta, G., Bernal, J. M. L., et al. (1995) · Clinical Infectious Diseases · doi:10.1093/clinids/20.2.272 · Cited by 118 · see citing works
A prospective study of HIV disease progression in female and male drug users
Webber, M. P., Schoenbaum, E. E., Gourevitch, M. N., Buono, D. L., & Klein, R. S. (1999) · AIDS · doi:10.1097/00002030-199902040-00014 · Cited by 115 · see citing works
Míguez‐Burbano, M. J., Burbano, X., Ashkin, D., Pitchenik, A. E., Rodriguez, A., Pineda-Medina, L., Rodriguez, N., & Shor‐Posner, G. (2003) · Addiction Biology · doi:10.1080/1355621031000069864 · Cited by 113 · see citing works
Passive Smoking and Tuberculosis
Leung, C. C. (2010) · Archives of Internal Medicine · doi:10.1001/archinternmed.2009.506 · Cited by 109 · see citing works
The association between cigarette smoking and selected HIV-related medical conditions.
Conley, L. J., Bush, T. J., Buchbinder, S., Penley, K. A., Judson, F. N., & Holmberg, S. D. (1996) · PubMed · Cited by 108 · see citing works
Inoue, Y., Koizumi, A., Wada, Y., Iso, H., Watanabe, Y., Date, C., Yamamoto, A., Kikuchi, S., Inaba, Y., Toyoshima, H., et al. (2007) · Journal of Epidemiology · doi:10.2188/jea.17.194 · Cited by 106 · see citing works
Lange, P., Vestbo, J., & Nyboe, J. (1995) · European Respiratory Journal · doi:10.1183/09031936.95.08101694 · Cited by 106 · see citing works
Smoking-related morbidity and mortality following liver transplantation
Leithead, J., Ferguson, J., & Hayes, P. C. (2008) · Liver Transplantation · doi:10.1002/lt.21471 · Cited by 105 · see citing works
Association Between Cigarette Smoking and Acute Respiratory Tract Illness in Young Adults
Aronson, M. D. (1982) · JAMA · doi:10.1001/jama.1982.03330020025023 · Cited by 105 · see citing works
The effect of cigarette smoking on the development of AIDS in HIV-1-seropositive individuals
Nieman, R. B., Fleming, J., Coker, R. J., Harris, J. R., & Mitchell, D. M. (1993) · AIDS · doi:10.1097/00002030-199305000-00015 · Cited by 104 · see citing works
Obesity and smoking are factors associated with poor prognosis in patients with bacteraemia
Huttunen, R., Laine, J., Lumio, J., Vuento, R., & Syrjänen, J. (2007) · BMC Infectious Diseases · doi:10.1186/1471-2334-7-13 · Cited by 102 · see citing works
Self-citationA Study of Risk Factors for Pneumococcal Disease among Children in a Rural Area of West Africa
O’Dempsey, T., MCARDLE, T. F., Morris, J., et al. (1996) · International Journal of Epidemiology · doi:10.1093/ije/25.4.885 · Cited by 100 · see citing works
Míguez‐Burbano, M. J., Ashkin, D., Rodriguez, A. E., DUNCAN, R. C., Pitchenik, A. E., Quintero, N., Flores, M., & Shor‐Posner, G. (2005) · International Journal of Infectious Diseases · doi:10.1016/j.ijid.2004.07.010 · Cited by 99 · see citing works
King, T. E., Savici, D., & Campbell, P. A. (1988) · The Journal of Infectious Diseases · doi:10.1093/infdis/158.6.1309 · Cited by 93 · see citing works
Effect of Smoking on the Clinical Progression of HIV-1 Infection
Galai, N., Park, L. P., Wesch, J. E., Visscher, B. R., Riddler, S. A., & Margolick, J. B. (1997) · Journal of Acquired Immune Deficiency Syndromes & Human Retrovirology · doi:10.1097/00042560-199704150-00009 · Cited by 91 · see citing works
Environmental Risk Factors for Community‐Acquired Pneumonia Hospitalization in Older Adults
Loeb, M. B., Neupane, B., Walter, S. D., Hanning, R. M., Carusone, S. C., Lewis, D., Krueger, P. D., Simor, A. E., Nicolle, L. E., & Marrie, T. J. (2009) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2009.02259.x · Cited by 89 · see citing works
Royce, R. A., & Winkelstein, W. (1990) · PubMed · Cited by 89 · see citing works
Disseminated cryptococcosis in HIV-uninfected patients
Chuang, Y.-H., Ho, Y., Chang, H.-Y., Yu, C., Yang, P., & Hsueh, P. (2007) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-007-0430-1 · Cited by 88 · see citing works
Cockerham, L. R., Scherzer, R., Zolopa, A. R., Rimland, D., Lewis, C. E., Bacchetti, P., Grünfeld, C., Shlipak, M. G., & Tien, P. C. (2009) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0b013e3181b79d22 · Cited by 85 · see citing works
Cayci, C., Russo, M., Cheema, F. H., Martens, T. P., Özcan, V., Argenziano, M., Oz, M. C., & Ascherman, J. A. (2008) · Annals of Plastic Surgery · doi:10.1097/sap.0b013e31815acb6a · Cited by 83 · see citing works
Environmental factors as disease accelerators during chronic hepatitis C
Mallat, A., Hézode, C., & Lotersztajn, S. (2008) · Journal of Hepatology · doi:10.1016/j.jhep.2008.01.004 · Cited by 78 · see citing works
Coates, R. A., Farewell, V. T., Raboud, J., Read, S., Macfadden, D. K., Calzavara, L., JOHNSON, J. K., Shepherd, F. A., & Fanning, M. M. (1990) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a115713 · Cited by 76 · see citing works
Lifestyle and 30-day complications to surgery for colorectal cancer
Nickelsen, T. N., Jørgensen, T., & Kronborg, O. (2005) · Acta Oncologica · doi:10.1080/02841860510029707 · Cited by 75 · see citing works
Risk Factors for Acute Symptomatic Coccidioidomycosis among Elderly Persons in Arizona, 1996–1997
Leake, J. A. D., Mosley, D. G., England, B., Graham, J., Plikaytis, B. D., Ampel, N. M., Perkins, B. A., & Hajjeh, R. A. (2000) · The Journal of Infectious Diseases · doi:10.1086/315400 · Cited by 74 · see citing works
Agarwal, R. (2005) · BMC Nephrology · doi:10.1186/1471-2369-6-13 · Cited by 72 · see citing works
Relationship of Smoking and Fibrosis in Patients With Chronic Hepatitis C
Dev, A. T., Patel, K., Conrad, A. J., Blatt, L. M., & McHutchison, J. G. (2006) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2006.03.019 · Cited by 72 · see citing works
Smoking and epidemic influenza-like illness in female military recruits: a brief survey.
Kark, J. D., & Lebiush, M. (1981) · American Journal of Public Health · doi:10.2105/ajph.71.5.530 · Cited by 72 · see citing works
Kyaw, M. H., Christie, P., Clarke, S. C., et al. (2003) · Clinical Infectious Diseases · doi:10.1086/379016 · Cited by 70 · see citing works
Stringer, K. A., Tobias, M., O’Neill, H. C., et al. (2007) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00325.2006 · Cited by 70 · see citing works
Smoking and Alanine Aminotransferase Levels in Hepatitis C Virus Infection
Wang, C.-S., Wang, S., Chang, T., Yao, W., & Chou, P. (2002) · Archives of Internal Medicine · doi:10.1001/archinte.162.7.811 · Cited by 70 · see citing works
Deep sternal wound infections following open heart surgery in Iceland. A population-based study
Steingrímsson, S., Gottfreðsson, M., Kristinsson, K. G., & Guðbjartsson, T. (2008) · Scandinavian Cardiovascular Journal · doi:10.1080/14017430801919557 · Cited by 68 · see citing works
Furber, A., Maheswaran, R., Newell, J. N., & Carroll, C. (2006) · Sexually Transmitted Infections · doi:10.1136/sti.2005.019505 · Cited by 68 · see citing works
HIV infection, cigarette smoking and CD4+ T-lymphocyte counts
Royce, R. A., & Winkelstein, W. (1990) · AIDS · doi:10.1097/00002030-199004000-00007 · Cited by 68 · see citing works
Burns, D., Krämer, A., Yellin, F. J., et al. (1991) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/00126334-199101000-00011 · Cited by 67 · see citing works
Effects of alcohol and nicotine on cytotoxic functions of human lymphocytes
Nair, M., Kronfol, Z., & Schwartz, S. A. (1990) · Clinical Immunology and Immunopathology · doi:10.1016/0090-1229(90)90053-s · Cited by 64 · see citing works
Madeddu, G., Porqueddu, E. M., Cambosu, F., et al. (2008) · Infection · doi:10.1007/s15010-007-7162-0 · Cited by 60 · see citing works
Recommended Adult Immunization Schedule: United States, 2009
Advisory Committee on Immunization Practices† (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-150-1-200901060-00008 · Cited by 53 · see citing works
Active and Passive Smoking and Risk of Colds in Women
Benseñor, I. (2001) · Annals of Epidemiology · doi:10.1016/s1047-2797(00)00214-3 · Cited by 52 · see citing works
Corrêa, P. C. R. P., Barreto, S. M., & Passos, V. M. (2009) · BMC Public Health · doi:10.1186/1471-2458-9-206 · Cited by 52 · see citing works
The effect of stopping smoking on cervical Langerhans'cells and lymphocytes
Szarewski, A., Maddox, P., Royston, P. J., Jarvis, M. J., Anderson, M., Guillebaud, J., & Cuzick, J. M. (2001) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2001.00074.x · Cited by 51 · see citing works
Limb Salvage for Chronic Tibial Osteomyelitis: An Outcomes Study
Siegel, H. J., Patzakis, M. J., Holtom, P. D., et al. (2000) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/00005373-200003000-00019 · Cited by 49 · see citing works
Effects of environmental tobacco smoke exposure on pulmonary immune response in infant monkeys
Wang, L., Joad, J. P., Zhong, C., & Pinkerton, K. E. (2008) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2008.04.011 · Cited by 48 · see citing works
Peivandi, A. A. (2003) · Cardiovascular Surgery · doi:10.1016/s0967-2109(03)00006-1 · Cited by 46 · see citing works
Craib, K. J. P., Schechter, M. T., Montaner, J. S. G., Le, T. N., Sestak, P., Willoughby, B., Voigt, R. F., Haley, L., & O’Shaughnessy, M. V. (1992) · PubMed · Cited by 44 · see citing works
Pearson, W. S., Dube, S. R., Ford, E. S., & Mokdad, A. H. (2008) · Preventive Medicine · doi:10.1016/j.ypmed.2008.11.001 · Cited by 42 · see citing works
Laurichesse, H., Romaszko, J. ‐., Nguyen, L. T., et al. (2001) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/pl00011269 · Cited by 36 · see citing works
Andrews, J., Chandrasekaran, P., & McSwiggan, D. A. (2009) · Gerontology · doi:10.1159/000212648 · Cited by 23 · see citing works
Association between cigarette smoking and acute respiratory tract illness in young adults
Aronson, M. (1982) · JAMA · doi:10.1001/jama.248.2.181 · Cited by 22 · see citing works
Arvanitidou, M., Katikaridou, E., Douboyas, J., & Tsakris, A. (2005) · Journal of Hospital Infection · doi:10.1016/j.jhin.2005.03.006 · Cited by 19 · see citing works
Abstinence from smoking reduce incisional wound infection:A randomized controlled trial
Sorensen, L., Karlsmark, T., & Gottrup, F. (2003) · Annals of Surgery · doi:10.1097/00000658-200307000-00001 · Cited by 18 · see citing works
Eskild, A., & Petersen, G. (1994) · Scandinavian Journal of Social Medicine · doi:10.1177/140349489402200309 · Cited by 17 · see citing works
Past Year Exam Question (1999) · Sexually Transmitted Infections · doi:10.1136/sti.75.4.247 · Cited by 17 · see citing works
Laurichesse, H., Romaszko, J. ‐., Nguyen, L. T., et al. (2001) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s100960100504 · Cited by 10 · see citing works
Twenty four risk factors responsible for nearly half of annual deaths, says WHO
Zarocostas, J. (2009) · BMJ · doi:10.1136/bmj.b4439 · Cited by 6 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Hernigou, J., & Schuind, F. (2019) · Bone & Joint Research · doi:10.1302/2046-3758.86.bjr-2018-0344.r1 · Cited by 109 · see citing works
A combination of high-dose vitamin C plus zinc for the common cold
Maggini, S., Beveridge, S., & Suter, M. (2012) · Journal of International Medical Research · doi:10.1177/147323001204000104 · Cited by 70 · see citing works
Skeletal System Biology and Smoke Damage: From Basic Science to Medical Clinic
Tarantino, U., Cariati, I., Greggi, C., Gasbarra, E., Belluati, A., Ciolli, L., Maccauro, G., Momoli, A., Ripanti, S., Falez, F., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126629 · Cited by 52 · see citing works
- Authors
- Huttunen, R., Heikkinen, T., & Syrjänen, J.
- Affiliations
- Tampere University (FI)
- Turku University Hospital (FI)
- Corresponding author
- Huttunen, R.
- Venue
- Journal of Internal Medicine
- Publisher
- Wiley
- Published
- 2010-12-22
- Volume
- 269
- Issue
- 3
- Pages
- 258-269
- ISSN
- 0954-6820 (ISSN-L)
- OpenAlex
- W1524886294
- Cited by
- 194
- References
- 144
- Citations by year
- 2026: 5 · 2025: 10 · 2024: 26 · 2023: 9 · 2022: 19 · 2021: 16 · 2020: 13 · 2019: 12 · 2018: 6 · 2017: 7 · 2016: 9 · 2015: 13 · 2014: 12 · 2013: 18 · 2012: 15
- FWCI
- 1.15
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Health Sciences › Medicine › Epidemiology › Pneumonia and Respiratory Infections
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Keywords
- smoking, infection outcomes, immune system, respiratory tract, skin and soft tissue infections, invasive pneumococcal disease, pneumonia, periodontitis, surgical site infection, tuberculosis, influenza, meningococcal disease, sepsis, environmental tobacco smoke, children, dose-dependent effects, bacterial infection
- MeSH terms
- Adult, Child, Disease Susceptibility, Humans, Infections, Prognosis, Respiratory Tract Infections, Risk Factors, Smoking, Tobacco Smoke Pollution
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review