Aromatase in the Brain: Not Just for Reproduction Anymore

Sexual Differentiation of the Central Nervous System

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How widespread is adult neurogenesis in mammals?

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Acute Effects of Estrogen on Neuronal Physiology

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Is brain estradiol a hormone or a neurotransmitter?

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Brain estrogen deficiency accelerates Aβ plaque formation in an Alzheimer's disease animal model

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Spatial Learning Depends on Both the Addition and Removal of New Hippocampal Neurons

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Ultrastructural localization of estrogen receptor β immunoreactivity in the rat hippocampal formation

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Aromatization of Androstenedione by the Anterior Hypothalamus of Adult Male and Female Rats

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AROMATIZATION OF ANDROSTENEDIONE BY THE DIENCEPHALON¹

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Anatomical Distribution and Cellular Basis for High Levels of Aromatase Activity in the Brain of Teleost Fish: Aromatase Enzyme and mRNA Expression Identify Glia as Source

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The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis

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Testosterone improves spatial memory in men with Alzheimer disease and mild cognitive impairment

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Identification of aromatase‐positive radial glial cells as progenitor cells in the ventricular layer of the forebrain in zebrafish

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Brain aromatase is neuroprotective

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Ovarian steroids influence cell proliferation in the dentate gyrus of the adult female rat in a dose‐ and time‐dependent manner

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Aromatase Immunoreactivity in Axon Terminals of the Vertebrate Brain

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Gonadal hormone modulation of hippocampal neurogenesis in the adult

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Testosterone and Aggression: Berthold, Birds and Beyond

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Does hormone therapy for the treatment of breast cancer have a detrimental effect on memory and cognition? A pilot study

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The role of aromatization in testosterone supplementation: Effects on cognition in older men

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Neurogenesis in the adult hippocampus

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Functional significance of the rapid regulation of brain estrogen action: Where do the estrogens come from?

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Androgen modulation of hippocampal synaptic plasticity

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Mechanisms in tissue-specific regulation of estrogen biosynthesis in humans

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Aromatase Cytochrome P450 and Extragonadal Estrogen Play a Role in Ischemic Neuroprotection

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Androgens Increase Spine Synapse Density in the CA1 Hippocampal Subfield of Ovariectomized Female Rats

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Hormonal regulation of brain circuits mediating male sexual behavior in birds.

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Androgen actions on central serotonin neurotransmission: relevance for mood, mental state and memory.

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Aromatase: a neuroprotective enzyme

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Estrogen formation in the brain

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Neuronal replacement in adult brain

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Brain aromatization of androgens.

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Low levels of estradiol facilitate, whereas high levels of estradiol impair, working memory performance on the radial arm maze.

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Rapid control of brain aromatase activity by glutamatergic inputs.

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Distribution of aromatase mRNA and protein in the brain and pituitary of female rainbow trout: Comparison with estrogen receptor α

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Memory impairments with adjuvant anastrozole versus tamoxifen in women with early-stage breast cancer

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Aromatase is pre-synaptic and sexually dimorphic in the adult zebra finch brain

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Estrogenic encounters: how interactions between aromatase and the environment modulate aggression.

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Aromatase expression in the human temporal cortex

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Low levels of estradiol facilitate, whereas high levels of estradiol impair, working memory performance on the radial arm maze.

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Neurosteroid synthesis in the hippocampus: Role in synaptic plasticity

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Localization of Aromatase in Synaptosomal and Microsomal Subfractions of Quail (Coturnix coturnix japonica) Brain

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Role of P450 Aromatase in Sex-Specific Astrocytic Cell Death

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Aromatase Expression by Reactive Astroglia Is Neuroprotective

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Rapid Upregulation of Aromatase mRNA and Protein Following Neural Injury in the Zebra Finch (Taeniopygia guttata)

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Aromatase immunoreactivity in the rat brain: Gonadectomy-sensitive hypothalamic neurons and an unresponsive “limbic ring” of the lateral septum-bed nucleus-amygdala complex

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Aromatase in the human central nervous system

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Direct and indirect effects of estrogen on rat hippocampus

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Gonadotropin-releasing hormone regulates spine density via its regulatory role in hippocampal estrogen synthesis

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Mode of Action and Functional Significance of Estrogen-Inducing Dendritic Growth, Spinogenesis, and Synaptogenesis in the Developing Purkinje Cell

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Brain aromatase: Roles in reproduction and neuroprotection

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AROMATIZATION OF ANDROSTENEDIONE BY LIMBIC SYSTEM TISSUE FROM HUMAN FOETUSES

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Expression of CYP19 (aromatase) mRNA in different areas of the human brain

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Rapid Regulation of Pain by Estrogens Synthesized in Spinal Dorsal Horn Neurons

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Radial glia express aromatase in the injured zebra finch brain

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Inhibition of hippocampal estrogen synthesis causes region-specific downregulation of synaptic protein expression in hippocampal neurons

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Brain aromatase expression after experimental stroke: Topography and time course

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Estrogen Deficient Male Mice Develop Compulsive Behavior

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Subcellular relationships between cholinergic terminals and estrogen receptor‐α in the dorsal hippocampus

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Proliferation and apoptosis of hippocampal granule cells require local oestrogen synthesis

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Estradiol stimulates progenitor cell division in the ventricular and subventricular zones of the embryonic neocortex

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Estrogen Mobilizes a Subset of Estrogen Receptor-α-Immunoreactive Vesicles in Inhibitory Presynaptic Boutons in Hippocampal CA1

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Diminished aromatase immunoreactivity in the hypothalamus, but not in the basal forebrain nuclei in Alzheimer’s disease

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High level estradiol impairs and low level estradiol facilitates non-spatial working memory

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Rapid changes in production and behavioral action of estrogens

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Sexual Behavior Activity Tracks Rapid Changes in Brain Estrogen Concentrations

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Oestrogen‐deficient female aromatase knockout (ArKO) mice exhibit ‘depressive‐like’ symptomatology

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Effects of Dehydroepiandrosterone and Flutamide on Hippocampal CA1 Spine Synapse Density in Male and Female Rats: Implications for the Role of Androgens in Maintenance of Hippocampal Structure

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Systemic and local administration of estradiol into the prefrontal cortex or hippocampus differentially alters working memory

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Polymorphisms in the CYP19 gene confer increased risk for Alzheimer disease

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Neuroprotection by the steroids pregnenolone and dehydroepiandrosterone is mediated by the enzyme aromatase

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Anastrozole improved testosterone-induced impairment acquisition of spatial learning and memory in the hippocampal CA1 region in adult male rats.

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Dehydroepiandrosterone Increases Hippocampal Spine Synapse Density in Ovariectomized Female Rats

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Estrogen provision by reactive glia decreases apoptosis in the zebra finch (Taeniopygia guttata)

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Neural aromatization accelerates the acquisition of spatial memory via an influence on the songbird hippocampus

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Sex differences, developmental changes, response to injury and cAMP regulation of the mRNA levels of steroidogenic acute regulatory protein, cytochrome p450scc, and aromatase in the olivocerebellar system

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Oestrogen Synthesis in the Hippocampus: Role in Axon Outgrowth

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Estrogen deficiency leads to apoptosis in dopaminergic neurons in the medial preoptic area and arcuate nucleus of male mice

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Estrogen synthesis in the spinal dorsal horn: a new central mechanism for the hormonal regulation of pain

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Striatal susceptibility to a dopaminergic neurotoxin is independent of sex hormone effects on cell survival and DAT expression but is exacerbated by central aromatase inhibition

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