Cited by 476Gastrointestinal motility and disordersGut microbiota and healthInfant Health and Development

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome

tana, c., umesaki, y., imaoka, a., handa, t., kanazawa, m., fukudo, s.·2009·Neurogastroenterology & Motility

DOI 10.1111/j.1365-2982.2009.01427.x

Open this paper in CoChat — free account

Abstract

BACKGROUND: The profile of intestinal organic acids in irritable bowel syndrome (IBS) and its correlation with gastrointestinal (GI) symptoms are not clear. We hypothesized in this study that altered GI microbiota contribute to IBS symptoms through increased levels of organic acids. METHODS: Subjects were 26 IBS patients and 26 age- and sex-matched controls. Fecal samples were collected for microbiota analysis using quantitative real-time polymerase chain reaction and culture methods, and the determination of organic acid levels using high-performance liquid chromatography. Abdominal gas was quantified by image analyses of abdominal X-ray films. Subjects completed a questionnaire for GI symptoms, quality of life (QOL) and negative emotion. KEY RESULTS: Irritable bowel syndrome patients showed significantly higher counts of Veillonella (P = 0.046) and Lactobacillus (P = 0.031) than controls. They also expressed significantly higher levels of acetic acid (P = 0.049), propionic acid (P = 0.025) and total organic acids (P = 0.014) than controls. The quantity of bowel gas was not significantly different between controls and IBS patients. Finally, IBS patients with high acetic acid or propionic acid levels presented with significantly worse GI symptoms, QOL and negative emotions than those with low acetic acid or propionic acid levels or controls. CONCLUSIONS & INFERENCES: These results support the hypothesis that both fecal microbiota and organic acids are altered in IBS patients. A combination of Veillonella and Lactobacillus is known to produce acetic and propionic acid. High levels of acetic and propionic acid may associate with abdominal symptoms, impaired QOL and negative emotions in IBS.

Integrity signals

Registry

Crossref · 10.1111/j.1365-2982.2009.01427.x

Cites

45 of 45 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Untitled work
(1992) · PubMed · Cited by 33,716
The MOS 36-ltem Short-Form Health Survey (SF-36): I. Conceptual Framework and Item Selection
Ware, J. E., & Sherbourne, C. D. (1992) · Medical Care · doi:10.1097/00005650-199206000-00002 · Cited by 30,033
A self-rating depression scale
ZUNG, W. W. K. (1965) · Archives of General Psychiatry · doi:10.1001/archpsyc.1965.01720310065008 · Cited by 9,813
The twenty-item Toronto Alexithymia Scale--I. Item selection and cross-validation of the factor structure
Bagby, R. M., Parker, J. D. A., & Taylor, G. J. (1994) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(94)90005-1 · Cited by 5,293
Functional Bowel Disorders
Longstreth, G. F., Thompson, W. G., Chey, W. D., Houghton, L. A., Mearin, F., & Spiller, R. C. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.11.061 · Cited by 4,856
Functional bowel disorders and functional abdominal pain
Thompson, W. G., Longstreth, G. F., Drossman, D. A., Heaton, K. W., Irvine, E. J., & Müller-Lissner, S. A. (1999) · Gut · doi:10.1136/gut.45.2008.ii43 · Cited by 2,440
Psychological Stress and Susceptibility to the Common Cold
Cohen, S., Tyrrell, D. A. J., & Smith, A. P. (1991) · New England Journal of Medicine · doi:10.1056/nejm199108293250903 · Cited by 1,712
The irritable bowel severity scoring system: a simple method of monitoring irritable bowel syndrome and its progress
FRANCIS, C. Y., MORRIS, J., & WHORWELL, P. J. (1997) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.1997.142318000.x · Cited by 1,708
Lactobacillus and bifidobacterium in irritable bowel syndrome: Symptom responses and relationship to cytokine profiles
O’Mahony, L., McCarthy, J., Kelly, P., Hurley, G., Luo, F., Chen, K., O’Sullivan, G. C., Kiely, B., Collins, J. K., Shanahan, F., et al. (2005) · Gastroenterology · doi:10.1053/j.gastro.2004.11.050 · Cited by 1,448
GSRS—A clinical rating scale for gastrointestinal symptoms in patients with irritable bowel syndrome and peptic ulcer disease
Svedlund, J., Sjödin, I., & Dotevall, G. (1988) · Digestive Diseases and Sciences · doi:10.1007/bf01535722 · Cited by 1,319

Show all 45 references

Research works printed but not linked: 2

Speilberger, 1970, STAI Manual, 23
Brierley, 2008, Novel and specific roles for the inon channel TRPA1 in visceral sensory transduction, Gastroenterology, 134

Sorted by citations

Items 401–476 of 476

Effect of a Symbiotic Mixture on Fecal Microbiota in Pediatric Patients Suffering of Functional Abdominal Pain Disorders
Becheanu, C. A., Smadeanu, R. E., & Ţincu, I. F. (2021) · Processes · doi:10.3390/pr9122157 · Cited by 2
Results from a Cross-Sectional Observational Study Examining Irritable Bowel Syndrome Patients Six Months After Finishing Their Participation in the ViIBS Trial
Sommermeyer, H., Chmielowiec, K., Bernatek, M., Olszewski, P., Kopczyński, J., & Piątek, J. (2024) · Nutrients · doi:10.3390/nu16223911 · Cited by 2
Using metabolomics to analyse the role of gut microbiota in nutrition and disease
Xie, G., & Jia, W. P. (2014) · Elsevier eBooks · doi:10.1016/b978-1-78242-084-2.00006-x · Cited by 2
Current Status of Translational Research on Irritable Bowel Syndrome
Kwon, Y. H., & Kim, H. J. (2016) · Korean Journal of Gastroenterology · doi:10.4166/kjg.2016.68.3.138 · Cited by 2
Role of microbial fermentation products in irritable bowel syndrome
Fukudo, S., Umesaki, Y., Imaoka, A., Tana, C., Handa, T., & Kanazawa, M. (2010) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2010.01570.x · Cited by 2
Self-citation
“Gährungsdyspepsie” Revisited
Valeur, J., Undseth, R., & Berstad, A. (2016) · The American Journal of Gastroenterology · doi:10.1038/ajg.2015.361 · Cited by 2
THE GUT-BRAIN AXIS: EXPLORING THE ROLE OF INTESTINAL MICROBIOTA IN THE DEVELOPMENT OF FUNCTIONAL GASTROINTESTINAL DISORDERS LIKE IRRITABLE BOWEL SYNDROME (IBS)
Khan, N. T. A. (2024) · doi:10.53555/sq0egv23 · Cited by 1
Understanding the Pathophysiology of IBS
Barbara, G., Dolci, M., Cremon, C., Barbaro, M., Bellacosa, L., Fucili, A., & Stanghellini, V. (2013) · EMJ Gastroenterology · doi:10.33590/emjgastroenterol/10314657 · Cited by 1
The Emerging Role of Microbiome–Gut–Brain Axis in Functional Gastrointestinal Disorders
Skonieczna‐Żydecka, K., Łoniewski, I., Koulaouzidis, A., & Marlicz, W. M. (2019) · Elsevier eBooks · doi:10.1016/b978-0-12-815249-2.00026-9 · Cited by 1
Gut Microbiome and Gastrointestinal Disorders
Legaki, E., Karanasou, E. A., & Gazouli, M. (2021) · The microbiomes of humans, animals, plants, and the environment · doi:10.1007/978-3-030-59642-2_3 · Cited by 2
What do experimental animal models of mood disorders tell clinicians about influence of probiotics on the gut-brain axis?
Staniak, N., Piaseczna-Spitaleri, E., & Biała, G. (2022) · Postępy Higieny i Medycyny Doświadczalnej · doi:10.2478/ahem-2022-0042 · Cited by 1
ANXIETY AND DEPRESSION IN IRRITABLE BOWEL SYNDROME
Śluzek, N., & Sieradocha, K. (2025) · Archiv Euromedica · doi:10.35630/2025/15/3.310 · Cited by 1
The Intestinal Microbiota and Intestinal Disease: Irritable Bowel Syndrome
Keren, N., & Gophna, U. (2011) · Springer eBooks · doi:10.1007/978-3-642-21680-0_15 · Cited by 1
Clinical Connections Between the Microbiota and Breast Cancer (Onset, Progression and Management)
Filippone, A., & Magno, S. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-819265-8.00099-1 · Cited by 1
A INFLUÊNCIA PSICOSSOMÁTICA EM PORTADORES DA SÍNDROME DO INTESTINO IRRITÁVEL
Duque, G. M., Pecemilis, I. S., Vargas, B. C. S., & Almeida, L. B. P. D. (2021) · Revista Científica da Faculdade de Medicina de Campos · doi:10.29184/1980-7813.rcfmc.350.vol.16.n2.2021 · Cited by 1
Immunohistochemical characterization of interstitial cells of Cajal (ICC) in the mouse intestine using whole mount preparations – with particular reference to their density, morphological features, and network patterns
Kawashima, S., Miyamoto-Kikuta, S., Ezaki, T., & Okamoto, T. (2020) · Archivum histologicum japonicum · doi:10.1679/aohc.80.1 · Cited by 1
The origins of pain in diverticular disease: peripheral or central?
Smith, J. K. (2013) · Nottingham ePrints (University of Nottingham) · Cited by 1
Characterization of Intestinal Microbiota in Healthy Adults and the Effect of Perturbations
Jalanka, J. (2014) · Työväentutkimus Vuosikirja · Cited by 1
Molecular detection of pathogens in southern bluefin tuna
Neumann, L. (2017) · UTAS Research Repository · doi:10.25959/23238653 · Cited by 1
The role of hydrogenotrophic microbiota in the human gut
Wang, T. (2022) · doi:10.18174/569022 · Cited by 1
Irritable Bowel Syndrome and Microbial Pathogenesis
Fong, I. W. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1670-2_1
GUT in FOCUS Symposium NOBEL FORUM, Karolinska Institutet
(2015) · Microbial Ecology in Health and Disease · doi:10.3402/mehd.v26.28480
Development of an integrated psychological and biological assessment protocol: the role of the brain-gut axis in irritable bowel syndrome
Nelson, E. (2012) · Swinburne figshare (Swinburne University of Technology) · doi:10.25916/sut.26271883
Variability of the human gut microbiota in space, time, and associated with the irritable bowel syndrome
Vicente, A. D. (2013) · Dialnet (Universidad de la Rioja)
useful inclusion of probiotics within the adequate management of patients with IBS - probiotics with full names, that is.
Álvarez-Sánchez, Á., Rey, E., Zakko, S. F., Yu, J., & Sm, M. (2013)
Subjective food hypersensitivity: Lifestyle and psychological factors
Lind, R. A. (2010) · NORA - Norwegian Open Research Archives
JORNADA DE ACTUALIZACIÓN EN GASTROENTEROLOGÍA APLICADA
Mearin, F., Juan, A. P., & Balboa, A. (2016)
I. The Role of the Gut Microbiota on Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)
Arai, M., Matsuoka, K., & Kanai∥, T. (2015) · Nihon Naika Gakkai Zasshi · doi:10.2169/naika.104.35 · Cited by 1
3. Physiology and Pathophysiology of Intestinal Motility.
Fukudo, S. (2011) · Nihon Naika Gakkai Zasshi · doi:10.2169/naika.100.139
Self-citation
Response to Valeur et al. and Farmer et al.
Choi, C. H., Ringel‐Kulka, T., & Ringel, Y. (2016) · The American Journal of Gastroenterology · doi:10.1038/ajg.2015.409
Interrogation of the Distal Gut Microbiota of Healthy Adolescents and those with Irritable Bowel Syndrome
Rigsbee, L. (2011) · CORE Scholar (Wright State University)
3）過敏性腸症候群（IBS）
福土, 審. (2010) · Nihon Naika Gakkai Zasshi · doi:10.2169/naika.99.2146
Self-citation
Clinical, psychosocial and therapeutic aspects of irritable bowel syndrome : results of cohort studies and aprobiotic intervention trial
Thijssen, A. Y. (2015) · Research Publications (Maastricht University) · doi:10.26481/dis.20151119at
Gut Microbial Metabolism in Health and Disease
Jia, W. P., & Rajani, C. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-802928-2.00038-2
過敏性腸症候群Irritable Bowel Syndrome
審, 福. (2013) · doi:10.11415/jpdd.20.23
Role of intestinal flora characteristics in traditional Chinese medicine-based diagnosis and treatment of spleen and stomach diseases
He, Y.-S., Hui, H.-Y., & Tan, Z. (2019) · World Chinese Journal of Digestology · doi:10.11569/wcjd.v27.i10.605
A systematic review of non-invasive manual therapies in the management of irritable bowel syndrome
Badenhorst, N. (2019) · DUT Open Scholar (Durban University of Technology) · doi:10.51415/10321/3244
Digital Beings as an option to study gut flora evolution and adaptationPreprint
de Mendonça, J. P. A., Teixeira, L. D. M. D. V., & Sato, F. (2019) · arXiv (Cornell University) · doi:10.48550/arxiv.1909.04560
Treatment of Chronic Constipation (Constipation and Intestinal Flora)
Osaki, H., Jodai, Y., Kamano, T., Funasaka, K., Nagasaka, M., Nakagawa, Y., Shibata, T., & Ohmiya, N. (2019) · Nihon Daicho Komonbyo Gakkai Zasshi · doi:10.3862/jcoloproctology.72.609
Irritable bowel syndrome – diagnostic and therapeutic recommendations considering the place of antispasmodics
Cybulska, A. M. (2019) · Pediatria i Medycyna Rodzinna · doi:10.15557/pimr.2019.0043
Diet and inflammatory bowel disease; a metabolomic approach
Keshteli, A. H. (2020) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3-47b0-nc90
Irritable bowel syndrome and the brain-gut connection
Pawlik, L., & Tarasiuk, A. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-821324-7.00003-4 · Cited by 1
Microbiote et syndrome de l’intestin irritable : que faut-il savoir ? Perspectives thérapeutiques
Bazin, T. (2020) · Côlon & Rectum · doi:10.3166/cer-2020-0141
Biotic nutritional components in baby formula: possible solution for infantile colic management
Berezovskaya, Y. V., Varakina-Mitrail, K., Nechaeva, V., & Kholodova, I. N. (2020) · Functional Foods in Health and Disease · doi:10.31989/ffhd.v10i9.737
The Key Role of Human Microbiota in Breast CancerPreprint
Filippone, A., Rossi, C., Rossi, M. M., Guarino, D., Maggiore, C., Micco, A. D., Ticca, L., Palma, S. D., Bolognino, R., Sánchez, A. M., et al. (2021) · Preprints.org · doi:10.20944/preprints202102.0393.v1
Influence du microbiote sur la douleur
Gervason, S., Defaye, M., Ardid, D., Berthon, J., Altier, C., Filaire, E., & Carvalho, F. A. (2021) · Douleur et Analgésie · doi:10.3166/dea-2021-0144
Microbiota-targeted therapeutics in gastrointestinal diseases
Shao, H., & Tan, Z. (2021) · World Chinese Journal of Digestology · doi:10.11569/wcjd.v29.i15.841
Volatile organic compounds analysis in the context of gastrointestinal health and disease
Baranska, A. L. (2021) · Research Publications (Maastricht University) · doi:10.26481/dis.20211129ab
Molecular Microbiology
Nolte, F. S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-816061-9.00005-9
The interplay between diet, gastrointestinal complaints and gut microbiota: more than a gut feeling?
Rijnaarts, I. (2022) · doi:10.18174/567948
The Relationship Between Affective Disorders and Pain: Focusing on the Functional Gastrointesinal Disorders such as Irritable Bowel Syndrome
Ali, M. (2020) · Annals of the Academy of Romanian Scientists Series on Biological Sciences · doi:10.56082/annalsarscibio.2020.2.50
Frequency of different clinical presentations/ symptoms of irritable bowel syndrome in patients presenting to the outpatient department of lady reading hospital Peshawar
Khan, K. Z., Sohail, M., Fahim, M., Khan, M. S., Gillani, S. R., Rehman, R., Khan, N., & Alam, U. (2023) · International Journal of Health Sciences · doi:10.53730/ijhs.v6ns10.13902
“An impact of Wi-Fi irradiation on the gut microbiome of rats”Preprint
Saliev, T. M., Kozhakhmetov, S., Nurgaziyev, M., Jarmukhanov, Z., Mureyev, S., Kushugulova, A. R., Fazylov, T., & Fakhradiyev, I. R. (2023) · Research Square · doi:10.21203/rs.3.rs-2673000/v1
Go with your gut: targeting the microbiome for treatment of irritable bowel syndrome
Fung, S. S.-P. (2023) · Drugs & Therapy Perspectives · doi:10.1007/s40267-023-01027-8
Gastrodin attenuates dextran sulfate sodium-induced colitis in mice via modulating gut microbiota and inhibiting NF-κB signaling pathway
Gao, X., Liu, X., Meng, X., Wang, M., Wang, M., Sun, B., Jia, C., Gao, J., Xu, C., Li, H., et al. (2024) · Food Science and Human Wellness · doi:10.26599/fshw.2024.9250221
Neurogastroenterology: Brain-Gut Axis, Stress, and Psychological Factors
Fukudo, S., Yamaguchi, Y., Sato, Y., Endo, Y., Shoji, T., Tamura, D., Tsushima, H., Muratsubaki, T., Kano, M., & Kanazawa, M. (2024) · Springer eBooks · doi:10.1007/978-981-97-8410-3_3
Self-citation
Future Direction of Research and Treatment Possibility for Irritable Bowel Syndrome
Fukudo, S., Yamaguchi, Y., Endo, Y., Shoji, T., Moue, S., Goto, K., Sato, Y., Muratsubaki, T., Kano, M., & Kanazawa, M. (2024) · Springer eBooks · doi:10.1007/978-981-97-8410-3_19
Self-citation
Mucosal Inflammation and Visceral Hypersensitivity in Irritable Bowel Syndrome
Komori, K., Ihara, E., & Akiho, H. (2024) · Springer eBooks · doi:10.1007/978-981-97-8410-3_6
Integrative analysis of the efficacy and mechanism on Changkang granules for treating irritable bowel syndrome rats
Yang, R., He, J., Wang, J., Xue, X., Zhou, G., Song, Z.-H., He, Y., Ma, X., Liu, L., & Li, X. (2025) · Heliyon · doi:10.1016/j.heliyon.2025.e42926
Role of KV and BK Channels in the Effects of Sodium Butyrate on Colon Motility in a Mouse Model of Irritable Bowel Syndrome
Shaidullov, I. F., Bouchareb, D., Sorokina, D. M., & Ситдикова, Г. Ф. (2025) · Biochemistry (Moscow) Supplement Series A Membrane and Cell Biology · doi:10.1134/s1990747825700308
Relationship between gastrointestinal environment and physical conditions in elite athletes
Akazawa, N., Nakamura, M., Eda, N., Murakami, H., Nakagata, T., Nanri, H., Park, J., Hosomi, K., Mizuguchi, K., Kunisawa, J., et al. (2025) · The Journal of Physical Fitness and Sports Medicine · doi:10.7600/jpfsm.2024.040
Antibiotics alter duodenal immune populations upon gluten exposure in mice: implications for non-coeliac gluten sensitivity
Pryor, J. C., Hoedt, E. C., Soh, W. S., Fowler, S., Caban, S., Minahan, K., Sherwin, S. K., Nieva, C., McCarthy, H., Horvat, J. C., et al. (2025) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00159.2025
Unexplained, self-reported food hypersensitivity. Explorative studies on mechanisms of abdominal symptom generation
Valeur, J. (2010) · NORA - Norwegian Open Research Archives · doi:10.13140/2.1.1357.4089
Impact d'un polluant environnemental, le benzo[a]pyrène, sur le microbiote intestinal en modèle murin
Ribière, C. (2015) · theses.fr (ABES) · doi:10.70675/3235c2c3z2d52z4177z81a6z661b79958ea6
Blastocystis spp., de l'épidémiologie à la physiopathologie. Quel lien avec le syndrome de l'intestin irritable ?
Nourrisson, C. (2017) · theses.fr (ABES) · doi:10.70675/c54115d2z5b87z4564za955z61887e77ecfe
La vulnérabilité psychologique et physiologique en situation de stress : effets de la cohérence cardiaque et de la mindfulness et intérêt de l'évaluation de l'alexithymie dans cette vulnérabilité
Fournier, A. (2017) · theses.fr (ABES) · doi:10.70675/097f4051z4083z465az9a75z57441cf8835c
Non-small cell lung cancer, immunity and microbiota : laying ground for the gut-lung-lung cancer axis in human subjects
Bingula, R. (2019) · theses.fr (ABES) · doi:10.70675/0634dca5z63c4z42bdza47azaf2d4eb69fd8
Increased intake of fermentable carbohydrates induces IBS-like symptoms : a complementary understanding of mechanisms involved
Kamphuis, J. B. J. (2019) · theses.fr (ABES) · doi:10.70675/e4003e6fzeffaz48a2z95a6zba874fe5eb4c
Régulation de la perméabilité intestinale au cours du syndrome de l'intestin irritable : role du système ubiquitine-protéasome et impact de l'obésité
Bahlouli, W. (2019) · theses.fr (ABES) · doi:10.70675/d11b6294za3f6z49d7zb053z7f8a27cb6dd1
Etude des perturbations de l'homéostasie intestinale en cas d'infection par citrobacter rodentium. Conséquences sur le bien-être de l'hôte
Baudu, E. (2018) · theses.fr (ABES) · doi:10.70675/42c7a86czd734z4a38zba45z18b45741ec10
РОЛЬ СОСТОЯНИЯ МИКРОБИОМА КИШЕЧНИКА В ВОЗНИКНОВЕНИИ СОМАТИЧЕСКИХ ЗАБОЛЕВАНИЙ
Волк, Т. Г., Гайкова, А. В., & Сафрутина, В. Н. (2026) · Вестник Смоленской государственной медицинской академии · doi:10.37903/vsgma.2026.2.10
Intestino irritable: una enfermedad orgánica en 2026
Díaz, J. A. U., Fernández, H. M., Ordoñez, J. S. F., Cheng, H. G. C., Espinoza‐Ríos, J., Parra, L. O., & Regino, W. O. (2026) · Revista de Gastroenterología del Perú · doi:10.47892/rgp.2026.462.2262
Mapping research trends in irritable bowel syndrome and the gut microbiome: a cross-database bibliometric analysis
Mo, W., Cai, F., Li, L., 梁靜蓉, Zhang, J., Yao, L. B., Mo, S., Liao, Y., Tang, S., Liu, Z., et al. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1900159
Comparative gut microbiome in diarrheal and non-diarrheal children: an individually matched case-control study
Xu, J., Fan, Y., Qu, G., Li, J., Peng, Y., Wang, M., Zhang, J., Feng, Y., Liu, X., Hu, Y., et al. (2026) · mSystems · doi:10.1128/msystems.00198-26
SCFA Alterations in IBS Subtypes: Systematic Evidence and Future Prospects for Biomarker-Based Diagnosis in India
Limaye, S., Bhide, P., Kale, A., & Bokey, N. (2026) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2605.05029
Research Progress on the Pathogenesis of Irritable Bowel Syndrome
盛, 淑. (2026) · Advances in Clinical Medicine · doi:10.12677/acm.2026.16103439

Authors: tana, C., umesaki, Y., imaoka, A., handa, T., kanazawa, M., & fukudo, S.
Affiliations: Tohoku University (JP)
Yakult Central Institute (JP)
Corresponding author: fukudo, s.
ORCID: umesaki, y.
Venue: Neurogastroenterology & Motility
Publisher: Wiley
Published: 2009-11
Volume: 22
Issue: 5
Pages: 512-9, e114
ISSN: 1350-1925 (ISSN-L)
1365-2982
DOI: 10.1111/j.1365-2982.2009.01427.x
OpenAlex: W1974577714
Cited by: 474
References: 45
Citations by year: 2026: 6 · 2025: 21 · 2024: 30 · 2023: 19 · 2022: 35 · 2021: 38 · 2020: 31 · 2019: 34 · 2018: 27 · 2017: 29 · 2016: 39 · 2015: 32 · 2014: 38 · 2013: 29 · 2012: 23
FWCI: 23.01
Type: journal article
Language: en
Open access: closed
Licence: doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 2130 d)
Locations: Neurogastroenterology & Motility (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Health and Development
Keywords: irritable bowel syndrome, gut microbiota, organic acids, acetic acid, propionic acid, Veillonella, Lactobacillus, gastrointestinal symptoms, quality of life, negative emotions, abdominal gas, fecal microbiota
MeSH terms: Adult, Analysis of Variance, Chromatography, High Pressure Liquid, DNA, Bacterial, Feces, Female, Humans, Immunoenzyme Techniques, Lactobacillus, Male, Propionates, Quality of Life, Surveys and Questionnaires, Severity of Illness Index, Veillonella, Case-Control Studies, Statistics, Nonparametric, Acetic Acid, Reverse Transcriptase Polymerase Chain Reaction, Irritable Bowel Syndrome, Metagenome

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Altered profiles of intestinal microbiota and organic acids may be the origin of symptoms in irritable bowel syndrome

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks