The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
microRNA‐directed cleavage of ATHB15 mRNA regulates vascular development in Arabidopsis inflorescence stems
Open accessAbstract
Summary: Class III homeodomain‐leucine zipper proteins regulate critical aspects of plant development, including lateral organ polarity, apical and lateral meristem formation, and vascular development. ATHB15, a member of this transcription factor family, is exclusively expressed in vascular tissues. Recently, a microRNA (miRNA) binding sequence has been identified in ATHB15 mRNA, suggesting that a molecular mechanism governed by miRNA binding may direct vascular development through ATHB15. Here, we show that miR166‐mediated ATHB15 mRNA cleavage is a principal mechanism for the regulation of vascular development. In a gain‐of‐function MIR166a mutant, the decreased transcript level of ATHB15 was accompanied by an altered vascular system with expanded xylem tissue and interfascicular region, indicative of accelerated vascular cell differentiation from cambial/procambial cells. A similar phenotype was observed in Arabidopsis plants with reduced ATHB15 expression but reversed in transgenic plants overexpressing an miR166‐resistant ATHB15. ATHB15 mRNA cleavage occurred in standard wheat germ extracts and in Arabidopsis and was mediated by miR166 in Nicotiana benthamiana cells. miR166‐assisted ATHB15 repression is likely to be a conserved mechanism that regulates vascular development in all vascular plants.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714
Cleavage of Scarecrow-like mRNA Targets Directed by a Class of Arabidopsis miRNA
Llave, C., Xie, Z., Kasschau, K. D., & Carrington, J. C. (2002) · Science · doi:10.1126/science.1076311 · Cited by 1,627
Steeves, T. A., & Sussex, I. M. (1989) · doi:10.1017/cbo9780511626227 · Cited by 1,334
Radial Patterning of Arabidopsis Shoots by Class III HD-ZIP and KANADI Genes
Emery, J. F., Floyd, S. K., Alvarez, J., Eshed, Y., Hawker, N. P., Izhaki, A., Baum, S. F., & Bowman, J. L. (2003) · Current Biology · doi:10.1016/j.cub.2003.09.035 · Cited by 1,143
MicroRNA regulation of the CUC genes is required for boundary size control in Arabidopsis meristems
Laufs, P., Peaucelle, A., Morin, H., & Traas, J. (2004) · Development · doi:10.1242/dev.01320 · Cited by 543
START: a lipid-binding domain in StAR, HD-ZIP and signalling proteins
Ponting, C. P., & Aravind, L. (1999) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(99)01362-6 · Cited by 398
Cited by
Williams, L., Grigg, S. P., Xie, M., Christensen, S., & Fletcher, J. C. (2005) · Development · doi:10.1242/dev.01942 · Cited by 448
Twenty years on: The inner workings of the shoot apical meristem, a developmental dynamo
Barton, M. K. (2010) · Developmental Biology · doi:10.1016/j.ydbio.2009.11.029 · Cited by 372
Modifying crops to increase cell wall digestibility
Jung, H.-J. G., Samac, D. A., & Sarath, G. (2012) · Plant Science · doi:10.1016/j.plantsci.2011.10.014 · Cited by 167
Li, H., Zhang, Z., Huang, F., Chang, L., & Ma, Y. (2009) · Plant Cell Reports · doi:10.1007/s00299-009-0693-3 · Cited by 46
Metadata
- Authors
- Kim, J., Jung, J., Reyes, J. L., Kim, Y., Kim, S., Chung, K., Kim, J. A., Lee, M., Lee, Y., Narry Kim, V., Chua, N., & Park, C.
- Venue
- The Plant Journal
- Publisher
- Wiley
- Published
- 2005-03-17
- Volume
- 42
- Issue
- 1
- Pages
- 84-94
- ISSN
- 0960-7412 (ISSN-L)
- 1365-313X
- OpenAlex
- W2146151246
- Cited by
- 388
- References
- 6
- FWCI
- 28.68
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: microRNA‐directed cleavage of ATHB15 mRNA regulates vascular development in Arabidopsis inflorescence stems. https://app.cochat.ai/papers/10.1111/j.1365-313x.2005.02354.x
- The paper
- Kim, J., Jung, J., Reyes, J. L., Kim, Y., Kim, S., Chung, K., Kim, J. A., Lee, M., Lee, Y., Narry Kim, V., Chua, N., & Park, C. (2005). microRNA‐directed cleavage of ATHB15 mRNA regulates vascular development in Arabidopsis inflorescence stems. The Plant Journal. https://doi.org/10.1111/j.1365-313x.2005.02354.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
