The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Ferritins control interaction between iron homeostasis and oxidative stress in Arabidopsis
Abstract
Summary: Ferritin protein nanocages are the main iron store in mammals. They have been predicted to fulfil the same function in plants but direct evidence was lacking. To address this, a loss‐of‐function approach was developed in Arabidopsis. We present evidence that ferritins do not constitute the major iron pool either in seeds for seedling development or in leaves for proper functioning of the photosynthetic apparatus. Loss of ferritins in vegetative and reproductive organs resulted in sensitivity to excess iron, as shown by reduced growth and strong defects in flower development. Furthermore, the absence of ferritin led to a strong deregulation of expression of several metal transporters genes in the stalk, over‐accumulation of iron in reproductive organs, and a decrease in fertility. Finally, we show that, in the absence of ferritin, plants have higher levels of reactive oxygen species, and increased activity of enzymes involved in their detoxification. Seed germination also showed higher sensitivity to pro‐oxidant treatments. Arabidopsis ferritins are therefore essential to protect cells against oxidative damage.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Chlorophyll fluorescence—a practical guide
Maxwell, K., & Johnson, G. N. (2000) · Journal of Experimental Botany · doi:10.1093/jexbot/51.345.659 · Cited by 9,347
The ferritins: molecular properties, iron storage function and cellular regulation
Harrison, P. M., & Arosio, P. (1996) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/0005-2728(96)00022-9 · Cited by 2,667 · cited 1×
“Ferritins are a class of universal 24-mer multi-meric proteins, present in all kingdoms of life and able to accommodate several thousand iron atoms in their central cavity (Harrison and Arosio, 1996).”
BackgroundIRT1, an Arabidopsis Transporter Essential for Iron Uptake from the Soil and for Plant Growth
Vert, G., Grotz, N., Dédaldéchamp, F., Gaymard, F., Guerinot, M. L., Briat, J.-F., & Curie, C. (2002) · The Plant Cell · doi:10.1105/tpc.001388 · Cited by 1,679
Self-citationThe ZIP family of metal transporters
Guerinot, M. L. (2000) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(00)00138-3 · Cited by 1,200
Iron and metal regulation in bacteria
Hantke, K. (2001) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(00)00184-3 · Cited by 755
Intracellular iron transport and storage: from molecular mechanisms to health implications
Mackenzie, E. L., Iwasaki, K., & Tsuji, Y. (2008) · Antioxidants & Redox Signaling · doi:10.1089/ars.2007.1893 · Cited by 526
Cited by
Barberon, M., Zelazny, E., Robert, S., Conéjéro, G., Curie, C., Friml, J., & Vert, G. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1100659108 · Cited by 473
Trace metal metabolism in plants
Andresen, E., Peiter, E., & Küpper, H. (2018) · Journal of Experimental Botany · doi:10.1093/jxb/erx465 · Cited by 431
Metals and seeds: Biochemical and molecular implications and their significance for seed germination
Kranner, I., & Colville, L. (2011) · Environmental and Experimental Botany · doi:10.1016/j.envexpbot.2010.05.005 · Cited by 342
Lanquar, V., Ramos, M. S., Lelièvre, F., Barbier-Brygoo, H., Krieger-Liszkay, A., Krämer, U., & Thomine, S. (2010) · Plant Physiology · doi:10.1104/pp.109.150946 · Cited by 337
An overview of heavy metal challenge in plants: from roots to shoots
DalCorso, G., Manara, A., & Furini, A. (2013) · Metallomics · doi:10.1039/c3mt00038a · Cited by 325
Metadata
- Authors
- Ravet, K., Touraine, B., Boucherez, J., Briat, J., Gaymard, F., & Cellier, F.
- Venue
- The Plant Journal
- Publisher
- Wiley
- Published
- 2009-01-26
- Volume
- 57
- Issue
- 3
- Pages
- 400-412
- ISSN
- 0960-7412 (ISSN-L)
- 1365-313X
- OpenAlex
- W2071069087
- Cited by
- 452
- References
- 6
- FWCI
- 33.17
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Ferritins control interaction between iron homeostasis and oxidative stress in Arabidopsis. https://app.cochat.ai/papers/10.1111/j.1365-313x.2008.03698.x
- The paper
- Ravet, K., Touraine, B., Boucherez, J., Briat, J., Gaymard, F., & Cellier, F. (2009). Ferritins control interaction between iron homeostasis and oxidative stress in Arabidopsis. The Plant Journal. https://doi.org/10.1111/j.1365-313x.2008.03698.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
