The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.
Probiotics in the treatment of atopic eczema/dermatitis syndrome in infants: a double‐blind placebo‐controlled trial
Abstract
Background: Probiotic bacteria are suggested to reduce symptoms of the atopic eczema/dermatitis syndrome (AEDS) in food‐allergic infants. We aimed to investigate whether probiotic bacteria have any beneficial effect on AEDS. Methods: Follow‐up of severity of AEDS by the Severity Scoring of Atopic Dermatitis (SCORAD) index in 230 infants with suspected cow's milk allergy (CMA) receiving, in a randomized double‐blinded manner, concomitant with elimination diet and skin treatment, Lactobacillus GG (LGG), a mixture of four probiotic strains, or placebo for 4 weeks. Four weeks after the treatment, CMA was diagnosed with a double‐blind placebo‐controlled (DBPC) milk challenge in 120 infants. Results: In the whole group, mean SCORAD (at baseline 32.5) decreased by 65%, but with no differences between treatment groups immediately or 4 weeks after the treatment. No treatment differences were observed in infants with CMA either. In IgE‐sensitized infants, however, the LGG group showed a greater reduction in SCORAD than did the placebo group, −26.1 vs−19.8 (P = 0.036), from baseline to 4 weeks after the treatment. Exclusion of infants who had received antibiotics during the study reinforced the findings in the IgE‐sensitized subgroup. Conclusion: Treatment with LGG may alleviate AEDS symptoms in IgE‐sensitized infants but not in non‐IgE‐sensitized infants.
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Cites
Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial
Kalliomäki, M., Salminen, S., Arvilommi, H., Kero, P., Koskinen, P., & Isolauri, E. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04259-8 · Cited by 2,432
Severity Scoring of Atopic Dermatitis: The SCORAD Index
(2009) · Dermatology · doi:10.1159/000247298 · Cited by 2,273
Johansson, S. G. O., Hourihane, J. O., Bousquet, J., Bruijnzeel-Koomen, C., Dreborg, S., Haahtela, T., Kowalski, M. L., Mygind, N., Ring, J., van Cauwenberge, P., et al. (2001) · Allergy · doi:10.1034/j.1398-9995.2001.t01-1-00001.x · Cited by 1,723
Self-citationGionchetti, P., Rizzello, F., Venturi, A., Brigidi, P., Matteuzzi, D., Bazzocchi, G., Poggioli, G., Miglioli, M., & Campieri, M. (2000) · Gastroenterology · doi:10.1053/gast.2000.9370 · Cited by 1,486
Distinct patterns of neonatal gut microflora in infants in whom atopy was and was not developing
Kalliomäki, M., Kirjavainen, P., Eerola, E., Kero, P., Salminen, S., & Isolauri, E. (2001) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2001.111237 · Cited by 1,255
Allergy development and the intestinal microflora during the first year of life
Björkstén, B., Sepp, E., Julge, K., Voor, T., & Mikelsaar, M. (2001) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2001.118130 · Cited by 1,203
Probiotics in the management of atopic eczema
Isolauri, E., Arvola, T., SÜtas, Y., Moilanen, E., & Salminen, S. (2000) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.2000.00943.x · Cited by 974
The intestinal microflora in allergic Estonian and Swedish 2‐year‐old children
Björkstén, Naaber, Sepp, & Mikelsaar (1999) · Clinical & Experimental Allergy · doi:10.1046/j.1365-2222.1999.00560.x · Cited by 927
Probiotics: A novel approach in the management of food allergy
Majamaa, H., & Isolauri, E. (1997) · Journal of Allergy and Clinical Immunology · doi:10.1016/s0091-6749(97)70093-9 · Cited by 918
Fuller, R. (1991) · Gut · doi:10.1136/gut.32.4.439 · Cited by 862
Cited by
Borchers, A. T., Selmi, C., Meyers, F. J., Keen, C. L., & Gershwin, M. E. (2009) · Journal of Gastroenterology · doi:10.1007/s00535-008-2296-0 · Cited by 499
Diagnosing and Managing Common Food Allergies: A Systematic Review
Chafen, J. J. S., Newberry, S. J., Riedl, M. A., Bravata, D. M., Maglione, M., Suttorp, M. J., Sundaram, V., Paige, N. M., Towfigh, A., Hulley, B. J., et al. (2010) · JAMA · doi:10.1001/jama.2010.582 · Cited by 482
The ‘microflora hypothesis’ of allergic diseases
Noverr, M. C., & Huffnagle, G. B. (2005) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2005.02379.x · Cited by 394
KAJANDER, K., HATAKKA, K., POUSSA, T., FÄRKKILÄ, M., & KORPELA, R. (2005) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2005.02579.x · Cited by 361
Self-citationFang, Z., Pan, T., Li, L., Wang, H., Zhu, J., Zhang, H., Zhao, J., Chen, W., & Lu, W. (2022) · Gut Microbes · doi:10.1080/19490976.2022.2044723 · Cited by 273
Metadata
- Authors
- Viljanen, M., Savilahti, E., Haahtela, T., Juntunen‐Backman, K., Korpela, R., Poussa, T., Tuure, T., & Kuitunen, M.
- Venue
- Allergy
- Publisher
- Wiley
- Published
- 2004-09-02
- Volume
- 60
- Issue
- 4
- Pages
- 494-500
- ISSN
- 0105-4538 (ISSN-L)
- 1398-9995
- OpenAlex
- W2165898725
- Cited by
- 478
- References
- 31
- FWCI
- 48.15
- Type
- journal article
- Language
- en
- Open access
- closed
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- Viljanen, M., Savilahti, E., Haahtela, T., Juntunen‐Backman, K., Korpela, R., Poussa, T., Tuure, T., & Kuitunen, M. (2005). Probiotics in the treatment of atopic eczema/dermatitis syndrome in infants: a double‐blind placebo‐controlled trial. Allergy. https://doi.org/10.1111/j.1398-9995.2004.00514.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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