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Cited by 55Bipolar Disorder and TreatmentSuicide and Self-Harm StudiesPersonality Disorders and Psychopathology

Social phobia is associated with suicide attempt history in bipolar inpatients

Perroud, Nader, Baud, Patrick, Preisig, Martin, Etain, Bruno, Bellivier, Franck, Favre, Sophie, Reber, Nadja, Ferrero, François +2 more·2007·Bipolar Disorders
DOI 10.1111/j.1399-5618.2007.00471.x
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Abstract

Objectives: In an attempt to reduce the phenotypical heterogeneity in an ongoing genetic study of suicidal behavior, we investigated the impact of comorbid anxiety disorders on suicidal behavior in bipolar disorder (BD) patients. Methods: Anxiety disorders were compared in 406 BD I and BD II patients with or without lifetime history of suicide attempt. Results: Among anxiety disorders, only social phobia (SP) was significantly associated with history of suicide attempt in BD [p < 0.001, odds ratio 4.26 (2.284–7.946)]. Moreover, onset of SP was found to precede onset of BD. Conclusions: This result suggests that SP is an important risk factor for suicidal behavior in BD. Further studies are required to determine whether comorbid SP may help to identify a more homogeneous BD sub‐group, especially when studies of suicidal behavior are conducted. A second question is whether SP identifies a sub‐group of subjects with BD who have a more severe illness course and whether treatment of SP with selective serotonin reuptake inhibitor (SSRI) antidepressants is associated with improvement or worsening of the course of BD.

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Crossref · 10.1111/j.1399-5618.2007.00471.x

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  • Social anxiety disorder is associated with increased rates of suicidal ideation and behaviour in people with bipolar disorder.

    “Several investigations have linked social anxiety disorder with increased rates of suicidal ideation and behaviour (Perroud et al. 2007; Kocabas et al. 2019; Amuk and Patel 2020; Masi et al. 2021), as well as with substance use problems (Yapici Eser et al. 2018) in people with bipolar disorder.”

    From Cognitive behavioural therapy for social anxiety disorder in people with bipolar disorder: a case series (2024) · cites this paper as Perroud et al. 2007

  • These associations are stronger for social anxiety disorder than for any other anxiety disorder in people with bipolar disorder.

    “These associations were stronger for social anxiety disorder than for any other anxiety disorder (Perroud et al. 2007; Yapici Eser et al. 2018; Kocabas et al. 2019).”

    From Cognitive behavioural therapy for social anxiety disorder in people with bipolar disorder: a case series (2024) · cites this paper as Perroud et al. 2007

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Authors
Perroud, N., Baud, P., Preisig, M., Etain, B., Bellivier, F., Favre, S., Reber, N., Ferrero, F., Leboyer, M., & Malafosse, A.
Affiliations
  • University Hospital of Geneva (CH)
  • University of Lausanne (CH)
  • Inserm (FR)
Corresponding author
Malafosse, Alain
ORCID
Venue
Bipolar Disorders
Publisher
Wiley
Published
2007-11
Volume
9
Issue
7
Pages
713-721
ISSN
  • 1398-5647 (ISSN-L)
  • 1399-5618
DOI
10.1111/j.1399-5618.2007.00471.x
OpenAlex
W2111882999
Cited by
55
References
60
Citations by year
2026: 1 · 2025: 1 · 2024: 2 · 2023: 2 · 2022: 2 · 2020: 4 · 2019: 5 · 2018: 5 · 2017: 2 · 2016: 1 · 2015: 5 · 2014: 4 · 2013: 3 · 2012: 3
FWCI
2.17
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 1 d)
Locations
  • Bipolar Disorders (publishedVersion)
  • PubMed (publishedVersion)
  • IRIS (submittedVersion)
  • SERVAL (Université de Lausanne) (submittedVersion)
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
  • Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Keywords
social anxiety disorder, suicide attempt history, bipolar disorder, comorbid anxiety disorders, suicidal behavior, risk factors, selective serotonin reuptake inhibitors, clinical course
MeSH terms
Adult, Aged, Anxiety Disorders, Bipolar Disorder, Female, Humans, Male, Middle Aged, Phobic Disorders, Psychiatric Status Rating Scales, Risk Factors, Severity of Illness Index, Suicide, Attempted, Comorbidity, Prevalence, Odds Ratio, Selective Serotonin Reuptake Inhibitors, Age of Onset, Diagnostic and Statistical Manual of Mental Disorders

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