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Cited by 398Chronic Obstructive Pulmonary Disease (COPD) ResearchRespiratory Support and MechanismsObesity, Physical Activity, Diet

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Impact of obesity on respiratory function

LITTLETON, STEPHEN W.·2012·Respirology
DOI 10.1111/j.1440-1843.2011.02096.x
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Abstract

Obesity has long been recognized as having significant effects on respiratory function. The topic has been studied for at least the last half century, and some clear patterns have emerged. Obese patients tend to have higher respiratory rates and lower tidal volumes. Total respiratory system compliance is reduced for a variety of reasons, which will be discussed. Lung volumes tend to be decreased, especially expiratory reserve volume. Spirometry, gas exchange and airway resistance all tend to be relatively well preserved when adjusted for lung volumes. Patients may be mildly hypoxaemic, possibly due to ventilation–perfusion mismatching at the base of the lungs, where microatelectasis is likely to occur. Weight loss leads to a reversal of these changes. For all of these changes, the distribution of fat, that is, upper versus lower body, may be more important than body mass index.

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Crossref · 10.1111/j.1440-1843.2011.02096.x

Cites

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  • Added weight on the thorax and abdomen (and also the neck) can significantly affect static and dynamic lung volumes along with respiratory mechanics, usually in a dose-response fashion.

    “Added weight on the thorax and abdomen (and also the neck), can significantly affect static and dynamic lung volumes along with respiratory mechanics,92–112 usually in a dose-response fashion.”

    From Pathogenesis of hyperinflation in chronic obstructive pulmonary disease (2014) · cites this paper as [92]

Citations

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Metadata

Authors
LITTLETON, S. W.
Affiliations
Rush University Medical Center (US)
Corresponding author
LITTLETON, STEPHEN W.
ORCID
LITTLETON, STEPHEN W.
Venue
Respirology
Publisher
Wiley
Published
2011-12-21
Volume
17
Issue
1
Pages
43-49
ISSN
  • 1323-7799 (ISSN-L)
  • 1440-1843
DOI
10.1111/j.1440-1843.2011.02096.x
OpenAlex
W1513829807
Cited by
398
References
3
Citations by year
2026: 23 · 2025: 29 · 2024: 31 · 2023: 23 · 2022: 32 · 2021: 44 · 2020: 34 · 2019: 35 · 2018: 23 · 2017: 24 · 2016: 30 · 2015: 19 · 2014: 25 · 2013: 16 · 2012: 9
FWCI
2.66
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations
  • Respirology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
  • Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
Keywords
obesity, respiratory function, respiratory compliance, tidal volume, respiratory rate, lung volume, expiratory reserve volume, hypoxemia, ventilation-perfusion mismatch, weight loss, body fat distribution, airway resistance, gas exchange
MeSH terms
Airway Resistance, Dyspnea, Female, Functional Residual Capacity, Humans, Lung, Lung Volume Measurements, Male, Obesity, Pulmonary Gas Exchange, Spirometry, Tidal Volume, Weight Loss, Body Mass Index, Thoracic Wall, Body Fat Distribution

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