The DOI matches its Crossref record; 114 of the 114 references it cites were found in a registry or an index.
Sleep function: current questions and new approaches
Open accessAbstract
The mammalian brain oscillates through three distinct global activity states: wakefulness, non‐rapid eye movement (NREM) sleep and REM sleep. The regulation and function of these ‘vigilance’ or ‘behavioural’ states can be investigated over a broad range of temporal and spatial scales and at different levels of functional organization, i.e. from gene expression to memory, in single neurons, cortical columns or the whole brain and organism. We summarize some basic questions that have arisen from recent approaches in the quest for the functions of sleep. Whereas traditionally sleep was viewed to be regulated through top‐down control mechanisms, recent approaches have emphasized that sleep is emerging locally and regulated in a use‐dependent (homeostatic) manner. Traditional markers of sleep homeostasis, such as the electroencephalogram slow‐wave activity, have been linked to changes in connectivity and plasticity in local neuronal networks. Thus waking experience‐induced local network changes may be sensed by the sleep homeostatic process and used to mediate sleep‐dependent events, benefiting network stabilization and memory consolidation. Although many questions remain unanswered, the available data suggest that sleep function will best be understood by an analysis which integrates sleep’s many functional levels with its local homeostatic regulation.
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“Further, our finding of marked alterations in adipocyte function after experimental sleep restriction challenges the widely held belief that the primary function of sleep is the restoration of central nervous system function (26–29) and suggests that sleep may play an equally important role in peripheral energy metabolism.”
From Impaired Insulin Signaling in Human Adipocytes After Experimental Sleep Restriction: A Randomized, Crossover Study (2012) · cites this paper as [28]
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Cites
Two-Process Model of Sleep Regulation
Binder, M. D., Hirokawa, N., & Windhorst, U. (2008) · Springer eBooks · doi:10.1007/978-3-540-29678-2_6166 · Cited by 3,900
Thalamocortical oscillations in the sleeping and aroused brain
Steriade, M., McCormick, D. A., & Sejnowski, T. J. (1993) · Science · doi:10.1126/science.8235588 · Cited by 3,564
Reactivation of hippocampal ensemble memories during sleep
Wilson, M. A., & McNaughton, B. L. (1994) · Science · doi:10.1126/science.8036517 · Cited by 3,118
Hypothalamic regulation of sleep and circadian rhythms
Saper, C. B., Scammell, T. E., & Lu, J. (2005) · Nature · doi:10.1038/nature04284 · Cited by 2,804
Homeostatic plasticity in the developing nervous system
Turrigiano, G. G., & Nelson, S. B. (2004) · Nature Reviews Neuroscience · doi:10.1038/nrn1327 · Cited by 2,485
Sleep function and synaptic homeostasis
Tononi, G., & Cirelli, C. (2006) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2005.05.002 · Cited by 2,151
Huber, R., Felice Ghilardi, M., Massimini, M., & Tononi, G. (2004) · Nature · doi:10.1038/nature02663 · Cited by 1,854
Boosting slow oscillations during sleep potentiates memory
Marshall, L., Helgadóttir, H., Mölle, M., & Born, J. (2006) · Nature · doi:10.1038/nature05278 · Cited by 1,792
The Neurobiology of Consolidations, Or, How Stable is the Engram?
Dudai, Y. (2004) · Annual Review of Psychology · doi:10.1146/annurev.psych.55.090902.142050 · Cited by 1,671
Coordinated memory replay in the visual cortex and hippocampus during sleep
Ji, D., & Wilson, M. A. (2007) · Nature Neuroscience · doi:10.1038/nn1825 · Cited by 1,669
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EEG delta oscillations as a correlate of basic homeostatic and motivational processes
Knyazev, G. G. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.10.002 · Cited by 776
Electroencephalography of response inhibition tasks: Functional networks and cognitive contributions
Huster, R. J., Enriquez‐Geppert, S., Lavallee, C. F., Falkenstein, M., & Herrmann, C. S. (2012) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2012.08.001 · Cited by 794
Sleep and the single neuron: the role of global slow oscillations in individual cell rest
Vyazovskiy, V. V., & Harris, K. D. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3494 · Cited by 386
Broussard, J. L., Ehrmann, D. A., Van Cauter, E., Tasali, E., & Brady, M. J. (2012) · Annals of Internal Medicine · doi:10.7326/0003-4819-157-8-201210160-00005 · Cited by 364
EEG microstates of wakefulness and NREM sleep
Brodbeck, V., Kuhn, A., von Wegner, F., Morzelewski, A., Tagliazucchi, E., Borisov, S. V., Michel, C. M., & Laufs, H. (2012) · NeuroImage · doi:10.1016/j.neuroimage.2012.05.060 · Cited by 301
Metadata
- Authors
- Vassalli, A., & Dijk, D.
- Affiliations
- University of Lausanne (CH)
- University of Surrey (GB)
- Venue
- European Journal of Neuroscience
- Publisher
- Wiley
- Published
- 2009-05
- Volume
- 29
- Issue
- 9
- Pages
- 1830-1841
- ISSN
- 0953-816X (ISSN-L)
- 1460-9568
- OpenAlex
- W1979724295
- Cited by
- 110
- References
- 114
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 6 · 2023: 4 · 2022: 5 · 2021: 8 · 2020: 3 · 2019: 6 · 2018: 7 · 2017: 4 · 2016: 2 · 2015: 11 · 2014: 9 · 2013: 9 · 2012: 14
- FWCI
- 0.81
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- European Journal of Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- SERVAL (Université de Lausanne) (publishedVersion, other-oa)
- IRIS (submittedVersion)
- Open Research (University of Surrey) (submittedVersion)
- Surrey Research Insight Open Access (The University of Surrey) (submittedVersion)
- Funders
- Wellcome Trust
- Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung
- Directorate for Biological Sciences
- Biotechnology and Biological Sciences Research Council
- Air Force Office of Scientific Research
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroscience of respiration and sleep
- Keywords
- sleep function, sleep homeostasis, sleep-wake states, wakefulness, NREM sleep, REM sleep, slow-wave activity, network connectivity, memory consolidation, sleep regulation, top-down control
- MeSH terms
- Aging, Animals, Brain, Circadian Rhythm, Female, Homeostasis, Humans, Male, Memory, Neuronal Plasticity, Neurons, Sex Characteristics, Sleep, Synapses
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