Cited by 98Tuberculosis Research and EpidemiologyAutophagy in Disease and TherapyImmune responses and vaccinations

Innate immunity to mycobacteria: vitamin D and autophagy

Open access
Jo, Eun-Kyeong·2010·Cellular Microbiology

Abstract

Autophagy is an ancient mechanism of protein degradation and a novel antimicrobial strategy. With respect to host defences against mycobacteria, autophagy plays a crucial role in antimycobacterial resistance, and contributes to immune surveillance of intracellular pathogens and vaccine efficacy. Vitamin D3 contributes to host immune responses against Mycobacterium tuberculosis through LL-37/hCAP-18, which is the only cathelicidin identified to date in humans. In this review, we discuss recent advances in our understanding of host immune strategies against mycobacteria, including vitamin D-mediated innate immunity and autophagy activation. This review also addresses our current understanding regarding the autophagy connection to principal innate machinery, such as ubiquitin- or inflammasome-involved pathways. Integrated dialog between autophagy and innate immunity may contribute to adequate host immune defences against mycobacterial infection.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1111/j.1462-5822.2010.01491.x

Cites

77 of 77 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Jo, E.-K.
Affiliations
Chungnam National University (KR)
Corresponding author
Jo, Eun-Kyeong
Venue
Cellular Microbiology
Published
2010-06-14
Volume
12
Issue
8
Pages
1026-1035
ISSN
1462-5814 (ISSN-L)
OpenAlex
W1513303790
Cited by
98
References
77
Citations by year
2026: 2 · 2025: 1 · 2024: 2 · 2023: 5 · 2022: 3 · 2021: 7 · 2020: 11 · 2019: 1 · 2018: 3 · 2017: 5 · 2016: 6 · 2015: 8 · 2014: 8 · 2013: 8 · 2012: 14
FWCI
1.36
Type
journal article
Language
en
Open access
Locations
  • Cellular Microbiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
Chungnam National University
Topics
  • Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
  • Health Sciences › Medicine › Epidemiology › Autophagy in Disease and Therapy
  • Life Sciences › Immunology and Microbiology › Immunology › Immune responses and vaccinations
Keywords
innate immunity, mycobacteria, Mycobacterium tuberculosis, autophagy, vitamin D3, LL-37, cathelicidin, intracellular pathogens, vaccine efficacy, ubiquitin pathway, inflammasome, host-pathogen interaction
MeSH terms
Animals, Autophagy, Humans, Immunity, Innate, Models, Biological, Mycobacterium tuberculosis, Tuberculosis, Vitamin D, Vitamins

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review