Psychiatric Comorbidity in Migraine: A Review
Abstract
Investigations of migraine comorbidity have confirmed its association with diverse psychiatric conditions. This association appears to be strongest for major depression and anxiety disorders (particularly panic and phobia), but increased comorbidity has also been reported with substance abuse and certain mood disorders. This literature also indicates that greater psychiatric comorbidity exists for migraine sufferers with aura than without. Some support is found for the notion that psychiatric comorbidity is higher in transformed migraine than in simple migraine (particularly in the case of chronic substance abuse). However, research into the possible mechanisms underlying these associations remains limited. Studies examining the order of onset and the cross-transmission of migraine and psychiatric disorders in families have been unable to distinguish fully between causal and common aetiological models of association. The conclusions are discussed in light of both methodological and conceptual issues relevant to understanding migraine comorbidity.
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The proportion of patients with evidence of anxiety and depression in this study was comparable to previous studies.
“The proportion of patients with evidence of anxiety and depression in our study was comparable to previous studies [31].”
From Prevalence, management and burden of episodic and chronic headaches—a cross-sectional multicentre study in eight Austrian headache centres (2015) · cites this paper as [31]
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works
Diagnostic and Statistical Manual of Mental Disorders (DSM-IV)
Hu, R. J. (2003) · Elsevier eBooks · doi:10.1016/b0-12-226870-9/01070-4 · Cited by 9,167 · see citing works
Sorge, F., Simone, R. D., Marano, E., Nolano, M., Orefice, G., & Carrieri, P. B. (1988) · Cephalalgia · doi:10.1046/j.1468-2982.1988.0801001.x · Cited by 3,464 · see citing works
Diagnostic and Statistical Manual of Mental Disorders (DSM-III-R)
Spitzer, R. L., & Williams, J. (1987) · Cited by 1,621 · see citing works
Bowden, C. L. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.5.481 · Cited by 678 · see citing works
Wolff’s Headache and Other Head Pain
(2009) · Archives of Neurology · doi:10.1001/archneurol.2009.17 · Cited by 588 · see citing works
Migraine, psychiatric disorders, and suicide attempts: An epidemiologic study of young adults
Breslau, N., Davis, G. C., & Andreski, P. M. (1991) · Psychiatry Research · doi:10.1016/0165-1781(91)90102-u · Cited by 515 · see citing works
Merikangas, K. R. (1990) · Archives of General Psychiatry · doi:10.1001/archpsyc.1990.01810210057008 · Cited by 510 · see citing works
Migraine, quality of life, and depression
Lipton, R. B., Hamelsky, S. W., Kolodner, K., Steiner, T., & Stewart, W. F. (2000) · Neurology · doi:10.1212/wnl.55.5.629 · Cited by 478 · see citing works
Headache and major depression: Is the association specific to migraine?
Breslau, N., Schultz, L. R., Stewart, W. F., Lipton, R. B., Lucia, V. C., & Welch, K. M. A. (2000) · Neurology · doi:10.1212/wnl.54.2.308 · Cited by 465 · see citing works
Selective serotonin reuptake inhibitors: meta-analysis of efficacy and acceptability.
Song, F., Freemantle, N., Sheldon, T. A., House, A., Watson, P., Long, A., & Mason, J. (1993) · BMJ · doi:10.1136/bmj.306.6879.683 · Cited by 399 · see citing works
Wolff's Headache and Other Head Pain
Morris, G. L. (2002) · JAMA · doi:10.1001/jama.287.5.647 · Cited by 369 · see citing works
Migraine Prophylaxis With Divalproex
Mathew, N. T., Saper, J. R., Silberstein, S. D., Rankin, L., Markley, H. G., Solomon, S., Rapoport, A. M., Silber, C., & Deaton, R. (1995) · Archives of Neurology · doi:10.1001/archneur.1995.00540270077022 · Cited by 332 · see citing works
Headache and psychiatric comorbidity: clinical aspects and outcome in an 8-year follow-up study
Guidetti, V., Galli, F., Fabrizi, P., Giannantoni, A., Napoli, L., Bruni, O., & Trillo, S. (1998) · Cephalalgia · doi:10.1046/j.1468-2982.1998.1807455.x · Cited by 331 · see citing works
Breslau, N., & Davis, G. C. (1993) · Journal of Psychiatric Research · doi:10.1016/0022-3956(93)90009-q · Cited by 324 · see citing works
Migraine and Major Depression: A Longitudinal Study
Breslau, N., Davis, G. C., Schultz, L. R., & Paterson, E. L. (1994) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.1994.hed3407387.x · Cited by 312 · see citing works
Comorbidity of Depressive and Anxiety Disorders in Chronic Daily Headache and Its Subtypes
Juang, K., Wang, S., Fuh, J., Lu, S., & Su, T. (2000) · Headache The Journal of Head and Face Pain · doi:10.1046/j.1526-4610.2000.00148.x · Cited by 308 · see citing works
Headache syndromes and psychiatric disorders: Association and familial transmission
Merikangas, K. R., Merikangas, J. R., & Angst, J. (1993) · Journal of Psychiatric Research · doi:10.1016/0022-3956(93)90008-p · Cited by 272 · see citing works
Double‐Blind Trial of Fluoxetine: Chronic Daily Headache and Migraine
Saper, J. R., Silberstein, S. D., Lake, A. E., & Winters, M. E. (1994) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.1994.hed3409497.x · Cited by 234 · see citing works
Holroyd, K. A., & Penzien, D. B. (1990) · Pain · doi:10.1016/0304-3959(90)91085-w · Cited by 223 · see citing works
Comorbidity of Headache and Depressive Disorders
Mitsikostas, D., & Thomas, A. (1999) · Cephalalgia · doi:10.1046/j.1468-2982.1999.019004211.x · Cited by 220 · see citing works
Mental Disorders and the Incidence of Migraine Headaches in a Community Sample
Swartz, K., Pratt, L. A., Armenian, H. K., Lee, L.-C., & Eaton, W. W. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.10.945 · Cited by 172 · see citing works
Critical Issues in the Evaluation of Comorbidity of Psychiatric Disorders
Wïttchen, H. (1996) · The British Journal of Psychiatry · doi:10.1192/s000712500029836x · Cited by 167 · see citing works
Headache types and panic disorder
Breslau, N., Schultz, L. R., Stewart, W. F., Lipton, R. B., & Welch, K. M. A. (2001) · Neurology · doi:10.1212/wnl.56.3.350 · Cited by 161 · see citing works
Psychiatric Comorbidity in Chronic Daily Headache
Verri, A. P., Cecchini, A., Galli, C., Granella, F., Sandrini, G., & Nappi, G. (1998) · Cephalalgia · doi:10.1177/0333102498018s2112 · Cited by 145 · see citing works
Migraine and depression: Association and familial transmission
Merikangas, K. R., RISCH, N. J., Merikangas, J. R., Weissman, M. M., & Kídd, K. K. (1988) · Journal of Psychiatric Research · doi:10.1016/0022-3956(88)90076-3 · Cited by 143 · see citing works
Migraine: Association with Personality Characteristics and Psychopathology
Silberstein, S., Lipton, R. B., & Breslau, N. (1995) · Cephalalgia · doi:10.1046/j.1468-2982.1995.1505358.x · Cited by 135 · see citing works
Migraine and psychiatric comorbidity: From theory and hypotheses to clinical application
Sheftell, F. D., & Atlas, S. J. (2002) · Headache The Journal of Head and Face Pain · doi:10.1046/j.1526-4610.2002.02217.x · Cited by 116 · see citing works
Psychiatric Comorbidity Is Related to Headache Induced By Chronic Substance Use in Migraineurs
Radat, F., Sakh, D., Lutz, G., Amrani, M., Ferreri, M., & Bousser, M. (1999) · Headache The Journal of Head and Face Pain · doi:10.1046/j.1526-4610.1999.3907477.x · Cited by 98 · see citing works
Self-citationPsychopathology and Headache Syndromes in the Community
Merikangas, K. R., & Merikangas, K. R. (1994) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.1994.hed3408s17.x · Cited by 92 · see citing works
Steiner, T., Ahmed, F., Findley, L. J. J., MacGregor, E. A., & Wilkinson, M. (1998) · Cephalalgia · doi:10.1046/j.1468-2982.1998.1805283.x · Cited by 79 · see citing works
Comorbidity of headaches and depression in the elderly
Wang, S., Liu, H.-C., Fuh, J., Liu, C., Wang, P., & Lu, S. (1999) · Pain · doi:10.1016/s0304-3959(99)00057-3 · Cited by 78 · see citing works
Anxiety and Depression in Migraine
Devlen, J. (1994) · Journal of the Royal Society of Medicine · doi:10.1177/014107689408700613 · Cited by 67 · see citing works
Headache, Panic Disorder and Depression: Comorbidity or a Spectrum?
Marazziti, D., Toni, C., Pedri, S., Bonuccelli, U., Pavese, N., Nuti, A., MURATORIO, A., Cassano, G. B., & Akiskal, H. S. (2008) · Neuropsychobiology · doi:10.1159/000119182 · Cited by 65 · see citing works
Predicting outcome of relaxation therapy in headaches: The role of “depression”
Jacob, R. G., Turner, S. M., Szekely, B. C., & Eidelman, B. H. (1983) · Behavior Therapy · doi:10.1016/s0005-7894(83)80070-7 · Cited by 45 · see citing works
Diagnostic and Treatment Implications of Psychiatric Comorbidity with Migraine
Keck, P. E., Merikangas, K. R., McElroy, S. L., & Strakowski, S. M. (1994) · Annals of Clinical Psychiatry · doi:10.3109/10401239409148999 · Cited by 21 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Migraine and psychiatric comorbidity: a review of clinical findings
Antonaci, F., Nappi, G., Galli, F., Manzoni, G. C., Calabresi, P., & Costa, A. C. (2011) · The Journal of Headache and Pain · doi:10.1007/s10194-010-0282-4 · Cited by 417 · see citing works
Comorbidity of migraine and psychiatric disorders—a national population-based study
Jette, N., Patten, S., Williams, J., Becker, W., & Wiebe, S. (2008) · Headache: The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2007.00993.x · Cited by 363 · see citing works
Voxel‐Based Morphometry Reveals Gray Matter Abnormalities in Migraine
Valfrè, W., Rainero, I., Bergui, M., & Pinessi, L. (2007) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2007.00723.x · Cited by 343 · see citing works
Migraine: A Review on Its History, Global Epidemiology, Risk Factors, and Comorbidities
Amiri, P., Kazeminasab, S., Nejadghaderi, S. A., Mohammadinasab, R., Pourfathi, H., Araj‐Khodaei, M., Sullman, M. J. M., Kolahi, A., & Safiri, S. (2022) · Frontiers in Neurology · doi:10.3389/fneur.2021.800605 · Cited by 379 · see citing works
Fumal, A., Laureys, S., Clemente, L. D., Boly, M., Bohotin, V., Vandenheede, M., Coppola, G., Salmon, É., Kupers, R. C., & Schoenen, J. E. (2005) · Brain · doi:10.1093/brain/awh691 · Cited by 300 · see citing works
Dresler, T., Caratozzolo, S., Guldolf, K., Huhn, J.-I., Loiacono, C., Niiberg-Pikksööt, T., Puma, M., Sforza, G., Tobia, A., Ornello, R., et al. (2019) · The Journal of Headache and Pain · doi:10.1186/s10194-019-0988-x · Cited by 246 · see citing works
Headache, depression and anxiety: associations in the Eurolight project
Lampl, C., Thomas, H., Tassorelli, C., Katsarava, Z., Laínez, J. M., Lantéri‐Minet, M., Rastenytė, D., de la Torre, E. R., Stovner, L. J., Andrée, C., et al. (2016) · The Journal of Headache and Pain · doi:10.1186/s10194-016-0649-2 · Cited by 234 · see citing works
Balaban, C. D., Jacob, R. G., & FURMAN, J. M. R. (2011) · Expert Review of Neurotherapeutics · doi:10.1586/ern.11.19 · Cited by 214 · see citing works
Ramasubbu, R., Taylor, V. H., Samaan, Z., Sockalingham, S., Li, M., Patten, S., Rodin, G., Schaffer, A., Beaulieu, S., & McIntyre, R. S. (2012) · Annals of Clinical Psychiatry · doi:10.1177/104012371202400110 · Cited by 206 · see citing works
Behavioral management of headache triggers: Avoidance of triggers is an inadequate strategy
Martin, P. R., & MacLeod, C. (2009) · Clinical Psychology Review · doi:10.1016/j.cpr.2009.05.002 · Cited by 171 · see citing works
Holroyd, K. A., Drew, J., Cottrell, C., Romanek, K., & Heh, V. (2007) · Cephalalgia · doi:10.1111/j.1468-2982.2007.01420.x · Cited by 163 · see citing works
Mood and Anxiety Disorders in Chronic Headache
Baskin, S. M., Lipchik, G. L., & Smitherman, T. A. (2006) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2006.00559.x · Cited by 159 · see citing works
Impact of comorbidity on headache-related disability
Saunders, K. W., Merikangas, K. R., Low, N. C. P., Korff, M. V., & Kessler, R. C. (2008) · Neurology · doi:10.1212/01.wnl.0000297192.84581.21 · Cited by 157 · see citing works
Ayzenberg, I., Obermann, M., Nyhuis, P. W., Gastpar, M., Limmroth, V., Diener, H., Kaube, H., & Katsarava, Z. (2006) · Cephalalgia · doi:10.1111/j.1468-2982.2006.01183.x · Cited by 154 · see citing works
Clinical and psychopathological definition of the interictal dysphoric disorder of epilepsy
Mula, M., Jauch, R., Cavanna, A. E., Collimedaglia, L., Barbagli, D., Gaus, V., Kretz, R., Viana, M., Tota, G., Israel, H., et al. (2007) · Epilepsia · doi:10.1111/j.1528-1167.2007.01434.x · Cited by 151 · see citing works
The epidemiology of depression in metropolitan China
Lee, S., Tsang, A., Huang, Y., He, Y., Liu, Z., Zhang, M. Y., Shen, Y.-C., & Kessler, R. C. (2008) · Psychological Medicine · doi:10.1017/s0033291708004091 · Cited by 146 · see citing works
Co-morbidity of migraine with somatic disease in a large population-based study
Han, L., Tfelt‐Hansen, P. C., Russell, M. B., Skytthe, A., Kyvik, K. O., & Olesen, J. (2010) · Cephalalgia · doi:10.1177/0333102410373159 · Cited by 127 · see citing works
Increased Prevalence of Sleep Disorders in Chronic Headache: A Case–Control Study
Sancisi, E., Cevoli, S., Vignatelli, L., Nicodemo, M., Pierangeli, G., Zanigni, S., Grimaldi, D., Cortelli, P., & Montagna, P. (2010) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2010.01711.x · Cited by 117 · see citing works
Migraine and psychiatric disorders: comorbidities, mechanisms, and clinical applications
Baskin, S. M., & Smitherman, T. A. (2009) · Neurological Sciences · doi:10.1007/s10072-009-0071-5 · Cited by 116 · see citing works
Comorbidity of Migraine and Restless Legs Syndrome—A Case-Control Study
Rhode, A., Hösing, V., Happe, S., Biehl, K., Young, P., & Evers, S. (2007) · Cephalalgia · doi:10.1111/j.1468-2982.2007.01453.x · Cited by 111 · see citing works
Smitherman, T. A., McDermott, M. J., & Buchanan, E. M. (2011) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2011.01857.x · Cited by 106 · see citing works
Borsook, D., Erpelding, N., Lebel, A., Linnman, C., Veggeberg, R., Grant, P. E., Buettner, C., Becerra, L. R., & Burstein, R. (2014) · Neurobiology of Disease · doi:10.1016/j.nbd.2014.03.008 · Cited by 108 · see citing works
Pathophysiological Bases of Comorbidity in Migraine
Altamura, C., Corbelli, I., de Tommaso, M., Lorenzo, C. D., Lorenzo, G. D., Renzo, A. D., Filippi, M., Jannini, T. B., Messina, R., Parisi, P., et al. (2021) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2021.640574 · Cited by 110 · see citing works
Panic Disorder and Migraine: Comorbidity, Mechanisms, and Clinical Implications
Smitherman, T. A., Kolivas, E. D., & Bailey, J. (2012) · Headache The Journal of Head and Face Pain · doi:10.1111/head.12004 · Cited by 107 · see citing works
Camarda, C., Monastero, R., Pipia, C., Recca, D., & Camarda, R. (2007) · Cephalalgia · doi:10.1111/j.1468-2982.2007.01394.x · Cited by 103 · see citing works
Depression and anxiety behaviour in a rat model of chronic migraine
Zhang, M., Liu, Y., Zhao, M., Tang, W., Wang, X., Dong, Z., & Yu, S. (2017) · The Journal of Headache and Pain · doi:10.1186/s10194-017-0736-z · Cited by 99 · see citing works
The Migraine Cycle: Patient Burden of Migraine During and Between Migraine Attacks
Brandes, J. L. (2007) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2007.01004.x · Cited by 94 · see citing works
Is aerobic exercise helpful in patients with migraine? A systematic review and meta‐analysis
Touche, R. L., Fernández‐Pérez, J. J., Acosta, A. P., Campodónico, L. G., García, S. M., Juárez, D. A., Serrano-García, B., Angulo, S., Cuenca‐Martínez, F., Suso‐Martí, L., et al. (2020) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.13625 · Cited by 90 · see citing works
Physical and Mental Comorbidity of Headache in a Nationally Representative Sample of US Adults
Kalaydjian, A., & Merikangas, K. R. (2008) · Psychosomatic Medicine · doi:10.1097/psy.0b013e31817f9e80 · Cited by 88 · see citing works
A Twin Study of Depression and Migraine: Evidence for a Shared Genetic Vulnerability
Schur, E. A., Noonan, C., Buchwald, D., Goldberg, J. H., & Afari, N. (2009) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2009.01425.x · Cited by 85 · see citing works
A Review of Screening Tools for Psychiatric Comorbidity in Headache Patients
Maizels, M., Smitherman, T. A., & Penzien, D. B. (2006) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2006.00561.x · Cited by 85 · see citing works
Sleep Disturbance and Affective Comorbidity Among Episodic Migraineurs
Walters, A. B., Hamer, J. D., & Smitherman, T. A. (2013) · Headache The Journal of Head and Face Pain · doi:10.1111/head.12168 · Cited by 82 · see citing works
Hershenfeld, S. A., Wasim, S., McNiven, V., Parikh, M., Majewski, P., Faghfoury, H., & So, J. (2016) · Rheumatology International · doi:10.1007/s00296-015-3375-1 · Cited by 81 · see citing works
Cephalalgiaphobia: a possible specific phobia of illness
Peres, M. F. P., Mercante, J. P. P., Guendler, V. Z., Corchs, F., Bernik, M., Zukerman, E., & Silberstein, S. D. (2007) · The Journal of Headache and Pain · doi:10.1007/s10194-007-0361-3 · Cited by 79 · see citing works
Obsessive‐Compulsive Disorder and Migraine With Medication‐Overuse Headache
Cupini, L. M., Murtas, M. D., Costa, C., Mancini, M. L., Eusebi, P., Sarchielli, P., & Calabresi, P. (2009) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2009.01457.x · Cited by 78 · see citing works
Zebenholzer, K., Lechner, A., Broessner, G., Lampl, C., Luthringshausen, G., Wuschitz, A., Obmann, S.-M., Berek, K., & Wöber, C. (2016) · The Journal of Headache and Pain · doi:10.1186/s10194-016-0603-3 · Cited by 76 · see citing works
Migraine, Headaches, and Cognition
Martins, I. P., Gil‐Gouveia, R., Silva, C., Maruta, C., & Oliveira, A. G. (2012) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2012.02218.x · Cited by 75 · see citing works
Grazzi, L., Chiapparini, L., Ferraro, S., Usai, S., Andrasik, F., Mandelli, M. L., Bruzzone, M. G., & Bussone, G. (2010) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2010.01695.x · Cited by 74 · see citing works
Chen, H.-M., Chen, S.-F., Chen, Y.-H., & Lin, H.-C. (2009) · Cephalalgia · doi:10.1111/j.1468-2982.2009.01935.x · Cited by 71 · see citing works
Peterlin, B. L., Katsnelson, M. J., & Calhoun, A. H. (2009) · Current Pain and Headache Reports · doi:10.1007/s11916-009-0066-1 · Cited by 70 · see citing works
Irimia, P., Garrido‐Cumbrera, M., Lasaosa, S. S., Aguirre-Vazquez, M., Correa-Fernández, J., Colomina, I., & Pozo‐Rosich, P. (2021) · Scientific Reports · doi:10.1038/s41598-021-87352-2 · Cited by 69 · see citing works
Increased serotonin transporter availability in the brainstem of migraineurs
Schuh‐Hofer, S., Richter, M., Geworski, L., Villringer, A., Israel, H., Wenzel, R., Munz, D. L., & Arnold, G. (2007) · Journal of Neurology · doi:10.1007/s00415-006-0444-0 · Cited by 67 · see citing works
Boudreau, G., Grosberg, B. M., McAllister, P. J., Lipton, R. B., & Buse, D. C. (2015) · International Journal of General Medicine · doi:10.2147/ijgm.s70456 · Cited by 67 · see citing works
Wilcox, S. L., Veggeberg, R., Lemme, J. D., Hodkinson, D. J., Scrivani, S. J., Burstein, R., Becerra, L. R., & Borsook, D. (2016) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2016.00366 · Cited by 67 · see citing works
Accompanying symptoms and psychiatric comorbidity in migraine and tension-type headache patients
Mongini, F., Rota, E., Deregibus, A., Ferrero, L., Migliaretti, G., Cavallo, F., Mongini, T., & Novello, A. (2006) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2006.03.005 · Cited by 67 · see citing works
Martin, P. R., Aiello, R., Gilson, K., Meadows, G., Milgrom, J., & Reece, J. (2015) · Behaviour Research and Therapy · doi:10.1016/j.brat.2015.07.005 · Cited by 66 · see citing works
The relationship between migraine and mental disorders in a population-based sample
Ratcliffe, G. E., Enns, M. W., Jacobi, F., Belik, S., & Sareen, J. (2008) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2008.09.006 · Cited by 65 · see citing works
Behavioral Approaches to the Treatment of Migraine
Holroyd, K., & Drew, J. B. (2006) · Seminars in Neurology · doi:10.1055/s-2006-939920 · Cited by 65 · see citing works
Li, X. L., Fang, Y. N., Gao, Q. C., Lin, E. J., Hu, S. H., Ren, L., Ding, M. H., & Luo, B. N. (2010) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2010.01774.x · Cited by 64 · see citing works
One-day behavioral treatment for patients with comorbid depression and migraine: a pilot study
Dindo, L., Recober, A., Marchman, J. N., Turvey, C., & O'Hara, M. W. (2012) · Behaviour Research and Therapy · doi:10.1016/j.brat.2012.05.007 · Cited by 64 · see citing works
Systematic review of outcomes and endpoints in acute migraine clinical trials
Houts, C. R., McGinley, J. S., Nishida, T. K., Buse, D. C., Wirth, R. J., Dodick, D. W., Goadsby, P. J., & Lipton, R. B. (2021) · Headache The Journal of Head and Face Pain · doi:10.1111/head.14067 · Cited by 63 · see citing works
Bottiroli, S., Icco, R. D., Vaghi, G., Pazzi, S., Guaschino, E., Allena, M., Ghiotto, N., Martinelli, D., Tassorelli, C., & Sances, G. (2021) · The Journal of Headache and Pain · doi:10.1186/s10194-021-01333-4 · Cited by 62 · see citing works
Systematic review of outcomes and endpoints in preventive migraine clinical trials
McGinley, J. S., Houts, C. R., Nishida, T. K., Buse, D. C., Lipton, R. B., Goadsby, P. J., Dodick, D. W., & Wirth, R. J. (2021) · Headache The Journal of Head and Face Pain · doi:10.1111/head.14069 · Cited by 62 · see citing works
Migraine, headache, and the risk of depression: Prospective cohort study
Rist, P. M., Schürks, M., Buring, J. E., & Kurth, T. (2013) · Cephalalgia · doi:10.1177/0333102413483930 · Cited by 60 · see citing works
Psychiatric comorbidity in pediatric chronic daily headache
Slater, S. K., Kashikar‐Zuck, S., Allen, J. R., LeCates, S. L., Kabbouche, M. A., O’Brien, H. L., Hershey, A. D., & Powers, S. W. (2012) · Cephalalgia · doi:10.1177/0333102412460776 · Cited by 60 · see citing works
Smitherman, T. A., Maizels, M., & Penzien, D. B. (2007) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2007.00974.x · Cited by 59 · see citing works
Dindo, L. N., Recober, A., Haddad, R., & Calarge, C. A. (2016) · International Journal of Behavioral Medicine · doi:10.1007/s12529-016-9620-5 · Cited by 57 · see citing works
Detoxification for medication overuse headache is not necessary
Diener, H. (2011) · Cephalalgia · doi:10.1177/0333102411425867 · Cited by 57 · see citing works
Patterns of association of chronic medical conditions and major depression
Patten, S. B., Williams, J. V. A., Lavorato, D. H., Wang, J. L., Jetté, N., Sajobi, T. T., Fiest, K. M., & Bulloch, A. G. M. (2016) · Epidemiology and Psychiatric Sciences · doi:10.1017/s204579601600072x · Cited by 57 · see citing works
Psychopathological comorbidities in medication‐overuse headache: a multicentre clinical study
Sarchielli, P., Corbelli, I., Messina, P., Cupini, L. M., Bernardi, G., Bono, G., Piero, V. D., Petolicchio, B., Livrea, P., Prudenzano, M. P., et al. (2015) · European Journal of Neurology · doi:10.1111/ene.12794 · Cited by 54 · see citing works
Migraine headache and depression in adults: a systematic Review and Meta-analysis
Amiri, S., Behnezhad, S., & Azad, E. (2019) · Neuropsychiatrie · doi:10.1007/s40211-018-0299-5 · Cited by 57 · see citing works
One-day behavioral intervention in depressed migraine patients: effects on headache
Dindo, L., Recober, A., Marchman, J., O' Hara, M. W., & Turvey, C. (2014) · Headache: The Journal of Head and Face Pain · doi:10.1111/head.12258 · Cited by 52 · see citing works
Yaluğ, İ., Selekler, M., Erdoğan, A., Kutlu, A., Dundar, G., Ankaralı, H. Ç., & Aker, T. (2010) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2010.02093.x · Cited by 53 · see citing works
Anxiety, Stress and Coping Behaviours in Primary Care Migraine Patients: Results of the SMILE Study
Radat, F., Mekiès, C., Géraud, G., Valade, D., Vivès, E., Lucas, C., Joubert, J.-M., & Lantéri‐Minet, M. (2008) · Cephalalgia · doi:10.1111/j.1468-2982.2008.01644.x · Cited by 53 · see citing works
Self-citationBrain glycogen metabolism: A possible link between sleep disturbances, headache and depression
Petit, J.-M., Eren‐Koçak, E., Karataş, H., Magistretti, P. J., & Dalkara, T. (2021) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2021.101449 · Cited by 53 · see citing works
Serotonin in Trigeminal Ganglia of Female Rodents: Relevance to Menstrual Migraine
Berman, N. E. J., Puri, V., Chandrala, S., Puri, S., MacGregor, R. R., Liverman, C. S., & Klein, R. M. (2006) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2006.00528.x · Cited by 53 · see citing works
Trauma Exposure versus Posttraumatic Stress Disorder: Relative Associations With Migraine
Smitherman, T. A., & Kolivas, E. D. (2013) · Headache The Journal of Head and Face Pain · doi:10.1111/head.12063 · Cited by 52 · see citing works
Zebenholzer, K., Andree, C., Lechner, A., Broessner, G., Lampl, C., Luthringshausen, G., Wuschitz, A., Obmann, S.-M., Berek, K., & Wöber, C. (2015) · The Journal of Headache and Pain · doi:10.1186/s10194-015-0531-7 · Cited by 50 · see citing works
“Psychiatric comorbidity, in particular depression and anxiety, has been studied extensively in patients with recurrent or chronic headaches [31].”
BackgroundResultInfluentialMigraine in women with chronic pelvic pain with and without endometriosis
Karp, B. I., Sinaii, N., Nieman, L. K., Silberstein, S. D., & Stratton, P. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2010.11.037 · Cited by 51 · see citing works
Placebo and other psychological interactions in headache treatment
Autret, A., Valade, D., & Debiais, S. (2012) · The Journal of Headache and Pain · doi:10.1007/s10194-012-0422-0 · Cited by 52 · see citing works
The Role of Fear of Pain in Headache
Black, A. K., Fulwiler, J. C., & Smitherman, T. A. (2015) · Headache The Journal of Head and Face Pain · doi:10.1111/head.12561 · Cited by 50 · see citing works
Psychosocial Factors of Relevance to Sex and Gender Studies in Headache
Smitherman, T., & Ward, T. (2011) · Headache · doi:10.1111/j.1526-4610.2011.01919.x · Cited by 50 · see citing works
Borderline Personality Disorder and Migraine
Rothrock, J. F., Lopez, I., Zweilfer, R., Andress‐Rothrock, D., Drinkard, R., & Walters, N. (2007) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2007.00649.x · Cited by 50 · see citing works
Migraine in recurrent depression: case–control study
Samaan, Z., FARMER, A. E., Craddock, N. J., Jones, L. A., Korszun, A., Owen, M., & McGuffin, P. (2009) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.108.054049 · Cited by 47 · see citing works
Eskin, M., Akyol, A., Çelik, E., & Gültekin, B. K. (2013) · Scandinavian Journal of Psychology · doi:10.1111/sjop.12056 · Cited by 47 · see citing works
Therapeutic strategies in migraine patients with mood and anxiety disorders: clinical evidence
Finocchi, C., Villani, V., & Casucci, G. (2010) · Neurological Sciences · doi:10.1007/s10072-010-0297-2 · Cited by 45 · see citing works
Cephalalgiaphobia as a feature of high-frequency migraine: a pilot study
Giannini, G., Zanigni, S., Grimaldi, D., Melotti, R., Pierangeli, G., Cortelli, P., & Cevoli, S. (2013) · The Journal of Headache and Pain · doi:10.1186/1129-2377-14-49 · Cited by 45 · see citing works
Anxiety disorders and migraine intractability and progression
Smitherman, T. A., Penzien, D. B., & Maizels, M. (2008) · Current Pain and Headache Reports · doi:10.1007/s11916-008-0039-9 · Cited by 44 · see citing works
Migraine, depression, and brain volume
Gudmundsson, L. S., Scher, I., Sigurdsson, S. O., Geerlings, M. I., Vidal, J., Eiríksdóttir, G., Garcia, M., Harris, T. B., Kjartansson, Ó., Aspelund, T., et al. (2013) · Neurology · doi:10.1212/wnl.0b013e318295d69e · Cited by 44 · see citing works
Distribution of 5-HT1B and 5-HT1D receptors in the inner ear
Ahn, S.-K., & Balaban, C. D. (2010) · Brain Research · doi:10.1016/j.brainres.2010.05.057 · Cited by 44 · see citing works
Seng, E. K., & Holroyd, K. A. (2012) · Cephalalgia · doi:10.1177/0333102411436333 · Cited by 44 · see citing works
Physician and patient preferences for dosing options in migraine prevention
Cowan, R. P., Cohen, J. M., Rosenman, E. S., & Iyer, R. G. (2019) · The Journal of Headache and Pain · doi:10.1186/s10194-019-0998-8 · Cited by 44 · see citing works
Cerebrovascular dynamics in patients with migraine: Near-infrared spectroscopy study
Akın, A., Bilensoy, D., Emir, U. E., Gülsoy, M., Candansayar, S., & Bolay, H. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.02.016 · Cited by 44 · see citing works
Quality of life and psychiatric co‑morbidity in Indian migraine patients: A headache clinic sample
Sharma, K., Remanan, R., & Singh, S. (2013) · Neurology India · doi:10.4103/0028-3886.117584 · Cited by 43 · see citing works
Association of headache with childhood adversity and mental disorder: cross-national study
Lee, S., Tsang, A., Korff, M. V., de Graaf, R., Benjet, C. L., Haro, J. M., Angermeyer, M. C., Demyttenaere, K., de Girolamo, G., Gasquet, I., et al. (2009) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.108.052159 · Cited by 43 · see citing works
Endocrine Function Is Altered in Chronic Migraine Patients with Medication‐Overuse
Rainero, I., Ferrero, M., Rubino, E., Valfrè, W., Pellegrino, M., Arvat, E., Giordano, R., Ghigo, E., Limone, P. P., & Pinessi, L. (2006) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.2006.00409.x · Cited by 43 · see citing works
Depression and disability in migraine: the role of pain acceptance and values-based action
Dindo, L., Recober, A., Marchman, J., O’Hara, M., & Turvey, C. (2015) · International Journal of Behavioral Medicine · doi:10.1007/s12529-014-9390-x · Cited by 41 · see citing works
Generalized anxiety disorder, subthreshold anxiety and anxiety symptoms in primary headache
Lucchetti, G., Peres, M. F. P., Lucchetti, A. L. G., Mercante, J. P. P., Guendler, V. Z., & Zukerman, E. (2013) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2012.02405.x · Cited by 42 · see citing works
Smitherman, T. A., Davis, R. E., Walters, A. B., Young, J. N., & Houle, T. T. (2014) · Cephalalgia · doi:10.1177/0333102414557840 · Cited by 42 · see citing works
Traditional and Alternative Treatments for Depression: Implications for Migraine Management
Peck, K. R., Smitherman, T. A., & Baskin, S. M. (2015) · Headache The Journal of Head and Face Pain · doi:10.1111/head.12521 · Cited by 42 · see citing works
Anxiété et dépression chez l’enfant et l’adolescent migraineux : revue de la littérature
Amouroux, R., & Rousseau‐Salvador, C. (2008) · L Encéphale · doi:10.1016/j.encep.2007.08.005 · Cited by 42 · see citing works
Turner, D. P., Smitherman, T. A., Black, A. K., Penzien, D. B., Porter, J. A. H., Lofland, K. R., & Houle, T. T. (2015) · Pain · doi:10.1097/j.pain.0000000000000157 · Cited by 41 · see citing works
Personality in patients with migraine evaluated with the "Temperament and Character Inventory"
Sánchez-Román, S., Téllez-Zenteno, J. F., Zermeño-Pöhls, F., García-Ramos, G. S., Velázquez, A., Derry, P. A., Hernández, M., Rodríguez, A. R., & Guevara‐López, U. (2007) · The Journal of Headache and Pain · doi:10.1007/s10194-007-0352-9 · Cited by 40 · see citing works
Migraine and Mental Health in a Population-Based Sample of Adolescents
Orr, S. L., Potter, B. K., Ma, J., & Colman, I. (2016) · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques · doi:10.1017/cjn.2016.402 · Cited by 40 · see citing works
Chapter 3 Familial Hemiplegic Migraine
Barrett, C. F., van den Maagdenberg, A. M. J. M., Frants, R. R., & Ferrari, M. D. (2008) · Advances in genetics · doi:10.1016/s0065-2660(08)01003-1 · Cited by 39 · see citing works
Aaseth, K., Grande, R. B., Leiknes, K. A., Benth, J. Š., Lundqvist, C., & Russell, M. B. (2011) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.2011.01490.x · Cited by 39 · see citing works
Taheri, P., Mohammadi, F., Nazeri, M., Zarei, M. R., Chamani, G., Esfahlani, M. A., Taheri, F., & Shabani, M. (2020) · Heliyon · doi:10.1016/j.heliyon.2020.e05654 · Cited by 38 · see citing works
Chronic Headache: The Role of the Psychologist
Nicholson, R. A. (2010) · Current Pain and Headache Reports · doi:10.1007/s11916-009-0087-9 · Cited by 36 · see citing works
Relationship between MIDAS, depression, anxiety and alexithymia in migraine patients
Dikmen, P. Y., Aysevener, E. O., Kosak, S., Aydınlar, E. I., & Kocaman, A. S. (2017) · Acta Neurologica Belgica · doi:10.1007/s13760-017-0856-x · Cited by 35 · see citing works
Smitherman, T. A., Tietjen, G. E., Schuh, K. J., Skljarevski, V., Lipsius, S., D’Souza, D. N., & Pearlman, E. M. (2020) · Headache The Journal of Head and Face Pain · doi:10.1111/head.13970 · Cited by 34 · see citing works
- Authors
- Radat, F., & Swendsen, J.
- Affiliations
- Chronic Pain Treatment Unit, Centre Hospitalo-universitaire
- Université de Bordeaux (FR)
- Corresponding author
- Radat, F
- ORCID
- Venue
- Cephalalgia
- Publisher
- SAGE Publications
- Published
- 2005-03
- Volume
- 25
- Issue
- 3
- Pages
- 165-178
- ISSN
- 0333-1024 (ISSN-L)
- 1468-2982
- OpenAlex
- W2085382852
- Cited by
- 299
- References
- 36
- Citations by year
- 2026: 6 · 2025: 12 · 2024: 11 · 2023: 6 · 2022: 6 · 2021: 16 · 2020: 11 · 2019: 11 · 2018: 9 · 2017: 8 · 2016: 11 · 2015: 18 · 2014: 16 · 2013: 23 · 2012: 16
- FWCI
- 12.63
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cephalalgia (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Migraine and Headache Studies
- Health Sciences › Health Professions › Complementary and Manual Therapy › Temporomandibular Joint Disorders
- Health Sciences › Medicine › Epidemiology › Traumatic Brain Injury Research
- Keywords
- migraine, psychiatric comorbidity, major depressive disorder, anxiety disorders, panic disorder, phobia, substance abuse, mood disorders, migraine with aura, chronic migraine, familial aggregation
- MeSH terms
- Mental Disorders, Clinical Trials as Topic, Humans, Migraine Disorders, Risk Factors, Comorbidity, Risk Assessment
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