The DOI matches its Crossref record; 66 of the 67 references it cites were found in a registry or an index.
Psychiatric disorders in parents of children with autism: a meta-analysis
Abstract
Background: The genetic basis of autism has received great attention during the last few years. The psychiatric status of parents of persons with autism has been studied as part of the broad phenotype of autism. Methods: In the current study we examined all studies in which psychiatric difficulties of parents of children with autism were compared to those of parents of other children, as part of the broad phenotype of autism. Results: Overall, when parents of children with autism were compared to all other parents taken together, i.e., parents of typically developing children grouped together with parents of children with diagnoses other than autism, they were found to have more psychiatric difficulties, but this finding was inconsistent. Once type of comparison group (e.g., Down Syndrome, learning disabilities) and method of assessing psychiatric difficulties (e.g., self‐report, clinical measures) were taken into account, different findings were yielded for the various comparison groups and methods of assessing psychiatric difficulties in parents, suggesting that parents of children with autism present more psychiatric difficulties, mostly in comparisons involving samples of parents of children with no known genetic risk (e.g., Down Syndrome). Conclusions: These findings suggest that in future studies, researchers should carefully consider the advantages and disadvantages of various comparison groups and other characteristics, such as method of assessment, gender, and level of functioning, in attempting to delineate the specificity and universality of the broad phenotype of autism.
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“two meta-analyses (52, 97) underlined the lack of studies with psychiatric diagnosis of parents before the birth of children with autism, suggesting that depression during pregnancy may be underestimated.”
From Gene × Environment Interactions in Autism Spectrum Disorders: Role of Epigenetic Mechanisms (2014) · cites this paper as [97]
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369
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Depression in mothers and fathers of children with intellectual disability
Olsson, M. B., & Hwang, C. P. (2001) · Journal of Intellectual Disability Research · doi:10.1046/j.1365-2788.2001.00372.x · Cited by 829
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Sorted by citations
A meta-analysis of sensory modulation symptoms in individuals with autism spectrum disorders
Ben-Sasson, A., Hen, L., Fluss, R., Cermak, S. A., Engel-Yeger, B., & Gal, E. (2009) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-008-0593-3 · Cited by 1,047
“The selection of variables to code was based on the evidence cited in the literature review and on previous metaanalytic studies with persons with ASDs (Yirmiya and Shaked 2005).”
MethodThe genetics of autistic disorders and its clinical relevance: a review of the literature
Freitag, C. M. (2007) · Molecular Psychiatry · doi:10.1038/sj.mp.4001896 · Cited by 638
Herring, S., Gray, K., Taffe, J., Tonge, B., Sweeney, D., & Einfeld, S. (2006) · Journal of Intellectual Disability Research · doi:10.1111/j.1365-2788.2006.00904.x · Cited by 588
Estes, A., Olson, E., Sullivan, K., Greenson, J., Winter, J., Dawson, G., & Munson, J. (2013) · Brain and Development · doi:10.1016/j.braindev.2012.10.004 · Cited by 456
“Parents may also be at increased risk for developing psychological symptoms, such as depression and anxiety [1,6,7].”
Mugno, D., Ruta, L., D’Arrigo, V. G., & Mazzone, L. (2007) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-5-22 · Cited by 495
Metadata
- Authors
- Yirmiya, N., & Shaked, M.
- Affiliations
- Hebrew University of Jerusalem (IL)
- Corresponding author
- Yirmiya, Nurit
- Venue
- Journal of Child Psychology and Psychiatry
- Publisher
- Wiley
- Published
- 2004-08-11
- Volume
- 46
- Issue
- 1
- Pages
- 69-83
- ISSN
- 0021-9630 (ISSN-L)
- 1469-7610
- OpenAlex
- W2156078552
- Cited by
- 198
- References
- 67
- Citations by year
- 2026: 7 · 2025: 4 · 2024: 9 · 2023: 8 · 2022: 6 · 2021: 9 · 2020: 16 · 2019: 9 · 2018: 10 · 2017: 15 · 2016: 9 · 2015: 6 · 2014: 15 · 2013: 8 · 2012: 13
- FWCI
- 0.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Child Psychology and Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Social Sciences › Psychology › Clinical Psychology › Family and Disability Support Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Keywords
- autism spectrum disorder, parents of autistic children, mental illness, genetic risk, Down syndrome, learning disabilities, comparison groups, self-report measures, clinical measures
- MeSH terms
- Adult, Autistic Disorder, Mental Disorders, Child, Female, Humans, Male, Parent-Child Relations, Phenotype, Risk Factors, Incidence
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