The broader cognitive phenotype of autism in parents: how specific is the tendency for local processing and executive dysfunction?
Abstract
Background: The objective of this study was to investigate the tendency for local processing style (‘weak central coherence’) and executive dysfunction in parents of subjects with an autism spectrum disorder (ASD) compared with parents of individuals with early onset schizophrenia (EOS) and mental retardation (MR). Method: Sixty‐two parents of subjects with ASD, 36 parents of subjects with EOS and 30 parents of subjects with MR were examined. Data on two scales indicative of local visual processing (Embedded Figures Test, Block Design) and on three executive function tests (Wisconsin Card Sorting Test, Tower of Hanoi, Trailmaking Test) were collected for all participants. Results: Parents of subjects with ASD performed significantly faster on the Embedded Figures Test compared with both control samples. No other substantial group differences were observed. Conclusions: The findings indicate that an increased tendency for local processing in terms of visual disembedding could be a relatively specific core feature of the broader cognitive phenotype of autism in parents.
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ASD is both a clinically relevant phenomenon and a quantitative trait in the general population, with broader subclinical phenotypes frequently present in relatives.
“It is both a clinically relevant phenomenon, and a quantitative trait in the general population, with broader subclinical phenotypes frequently present in relatives [247, 248].”
From The contribution of environmental exposure to the etiology of autism spectrum disorder (2019) · cites this paper as [247]
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The contribution of environmental exposure to the etiology of autism spectrum disorder
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- Authors
- Bölte, S., & Poustka, F.
- Affiliations
- Goethe University Frankfurt (DE)
- Corresponding author
- Bölte, Sven
- ORCID
- Bölte, Sven
- Venue
- Journal of Child Psychology and Psychiatry
- Publisher
- Wiley
- Published
- 2006-05-18
- Volume
- 47
- Issue
- 6
- Pages
- 639-645
- ISSN
- 0021-9630 (ISSN-L)
- 1469-7610
- OpenAlex
- W2076426345
- Cited by
- 78
- References
- 28
- Citations by year
- 2026: 2 · 2022: 3 · 2021: 2 · 2020: 3 · 2019: 1 · 2018: 5 · 2017: 3 · 2016: 5 · 2015: 9 · 2014: 3 · 2013: 10 · 2012: 6
- FWCI
- 1.94
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Child Psychology and Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Deutsche Forschungsgemeinschaft
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Clinical Psychology › Family and Disability Support Research
- Keywords
- autism spectrum disorder, cognitive phenotypes, parents of autistic children, weak central coherence, local processing, executive dysfunction, early-onset schizophrenia, intellectual disability, Embedded Figures Test, block designs, Wisconsin Card Sorting Test, Tower of Hanoi, Trail Making Test
- MeSH terms
- Adult, Autistic Disorder, Child, Cognition Disorders, Humans, Intellectual Disability, Neuropsychological Tests, Parents, Phenotype, Schizophrenia, Severity of Illness Index
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