Pre‐ejection Period: Measuring Beta‐adrenergic Influences Upon the Heart
Abstract
Increasing interest among psychophysiologists in sympathetic (beta‐adrenergic) influences upon the heart has created the need for noninvasive techniques for assessing these influences. The validity of pre‐ejection period (PEP), a systolic time interval, as a measure of beta‐adrenergic influences upon myocardial contractility is evaluated. Details of a procedure for determining PEP using a polygraph and digital computer are presented. This methodology is then applied to an experiment in which the intracardiac (PEP) and arterial subintervals of pulse transmission time (PTT) are measured during biofeedback‐assisted control of PTT in order to evaluate the relative contribution of changes in PEP to PTT control.
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Four of the six cardiovascular measures (FPA, PTF, PTE, SBP) track changes mediated solely by the sympathetic nervous system.
“four measures (FPA, PTF, PTE, and SBP) track changes mediated solely by the sympathetic nervous system.”
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- Authors
- Newlin, D. B., & Levenson, R. W.
- Affiliations
- Indiana University (US)
- Corresponding author
- Levenson, Robert W.
- ORCID
- Levenson, Robert W.
- Venue
- Psychophysiology
- Publisher
- Wiley
- Published
- 1979-11
- Volume
- 16
- Issue
- 6
- Pages
- 546-552
- ISSN
- 0048-5772 (ISSN-L)
- 1469-8986
- OpenAlex
- W2055474620
- Cited by
- 275
- References
- 37
- Citations by year
- 2026: 4 · 2025: 15 · 2024: 9 · 2023: 8 · 2022: 14 · 2021: 21 · 2020: 18 · 2019: 11 · 2018: 17 · 2017: 12 · 2016: 10 · 2015: 12 · 2014: 13 · 2013: 4 · 2012: 6
- FWCI
- 3.61
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychophysiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Keywords
- pre-ejection period, sympathetic nervous system, cardiac contractility, systolic time intervals, biofeedback, heart rate variability, noninvasive cardiac assessment
- MeSH terms
- Heart, Humans, Myocardial Contraction, Pulse, Receptors, Adrenergic, Receptors, Adrenergic, beta, Systole
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