Cited by 114Endometriosis Research and TreatmentGynecological conditions and treatmentsEctopic Pregnancy Diagnosis and Management

‘Blood On The Tracks’ from corpora lutea to endometriomas*

Vercellini, P, Somigliana, E, Vigano, P, Abbiati, A, Barbara, G, Fedele, L·2009·BJOG: An International Journal of Obstetrics & Gynaecology

Abstract

Objective To detect a direct transition from a haemorrhagic corpus luteum to an endometriotic cyst by serial transvaginal ultrasonographic scans. Design Prospective observational study. Setting An academic tertiary care and referral centre for women with endometriosis. Population One hundred and nine women younger than 40 years, with regular menstrual cycles, undergoing first‐line surgery for endometriomas, and not wanting postoperative oral contraception. Methods Three‐monthly transvaginal ultrasonography during the luteal phase for 2 years after surgery. Main outcome measure Sonographic identification of progression from a haemorrhagic corpus luteum to a recurrent endometriotic cyst. Results A haemorrhagic corpus luteum was identified in 13 women. Serial ultrasonographic scans demonstrated transition to an endometriotic cyst in 11 (85%) instances and resorption in two. A unilateral endometriotic cyst without previous detection of a cystic corpus luteum was observed in 14 women. Conclusions Bleeding from a corpus luteum appears to be a critical event in the development of endometriomas.

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Crossref · 10.1111/j.1471-0528.2008.02055.x

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Authors
Vercellini, P., Somigliana, E., Vigano, P., Abbiati, A., Barbara, G., & Fedele, L.
Affiliations
University of Milan (IT)
Corresponding author
Vercellini, P
Venue
BJOG: An International Journal of Obstetrics & Gynaecology
Publisher
Wiley
Published
2009-01-21
Volume
116
Issue
3
Pages
366-371
ISSN
  • 0306-5456 (ISSN-L)
  • 1470-0328
  • 1471-0528
OpenAlex
W2017172690
Cited by
114
References
29
Citations by year
2026: 3 · 2025: 4 · 2024: 7 · 2023: 5 · 2022: 3 · 2021: 6 · 2020: 4 · 2019: 7 · 2018: 3 · 2017: 12 · 2016: 6 · 2015: 10 · 2014: 4 · 2013: 14 · 2012: 6
FWCI
10.24
Type
journal article
Language
en
Open access
closed
Locations
  • BJOG An International Journal of Obstetrics & Gynaecology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
  • Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ectopic Pregnancy Diagnosis and Management
Keywords
endometrioma, corpus luteum, endometriosis, endometriotic cysts, cyst progression, transvaginal ultrasound, luteal phase, endometrioma recurrence
MeSH terms
Adult, Corpus Luteum, Endometriosis, Female, Humans, Luteal Phase, Ovarian Cysts, Laparoscopy, Prospective Studies, Recurrence, Ultrasonography, Uterine Hemorrhage, Young Adult

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