The DOI matches its Crossref record; 45 of the 46 references it cites were found in a registry or an index.
Sleep Disturbance, Psychosocial Correlates, and Cardiovascular Disease in 5201 Older Adults: The Cardiovascular Health Study
Abstract
OBJECTIVES: To describe the prevalence of self reported sleep disturbances in older men and women and to describe their relationships with health status and cardiovascular disease (CVD). DESIGN: Cross-sectional study of sleep disturbance, CVD, general health, psychosocial factors, physical function, and use of psychotropic medications. SETTING: Participants of the Cardiovascular Health Study, 5201 adults aged 65 and older recruited from a random sample of noninstitutionalized Medicare enrollees in four US communities. MEASURES: Self-reported sleep disturbances and standardized questionnaires for cardiopulmonary symptoms and diseases, depression, social support, activities of daily living, physical activity, cognitive function, and current medications, spirometry, ECG, echocardiography, and carotid ultrasound. RESULTS: Women were twice as likely as men to report difficulty falling asleep (30% vs 14%). Daytime sleepiness, difficulty falling asleep, and frequent awakenings increased in prevalence with age. All symptoms were related strongly to depression. Symptoms of daytime sleepiness were also related strongly to poor health and limitations in activities of daily living in men and women. In multivariate analysis, men taking benzodiazepines were likely to report difficulty falling asleep and daytime sleepiness, whereas women taking benzodiazepines reported difficulty falling asleep and waking up too early. After accounting for these factors, the only cardiovascular disease independently associated with sleep disturbances was angina. Men and women with confirmed angina were 1.6 times more likely to report trouble falling asleep. Independent relationships between sleep disturbances and cardiovascular risk factors such as obesity, hypertension, smoking, and diabetes were relatively weak and inconsistent, though smokers were less likely to report frequent awakenings. CONCLUSIONS: Sleep disturbances are relatively common in older men and women and are associated with poor health, depression, angina, limitations in activities of daily living, and the use of benzodiazepines.
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“Indeed, the different relationships between problems with sleep onset, maintenance, and negative affect reported here stands in contrast to studies which find that both sleep onset and sleep maintenance problems are related to negative affect [96–100].”
From A structural equation model of the relationship between insomnia, negative affect, and paranoid thinking (2017) · cites this paper as [98]
In the citing paper
“Sleep duration is associated with cardiovascular disease and diabetes risk factors, depression, automobile and workplace accidents, and prospective mortality.”
From Sleep Duration in the United States: A Cross-sectional Population-based Study (2009) · cites this paper as [6]
In the citing paper
“our results show that non-Hispanic black race/ethnicity (23), low levels of socioeconomic status (7,35), depression (6, 7), and cardiovascular disease and diabetes (1, 2) are associated with both long and short sleep duration.”
From Sleep Duration in the United States: A Cross-sectional Population-based Study (2009) · cites this paper as [6]
In the citing paper
“self-reported sleep duration reliably predicts prospective mortality and other health outcomes (1-7, 13-18).”
From Sleep Duration in the United States: A Cross-sectional Population-based Study (2009) · cites this paper as [6]
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“Keywords: Sleep quality; Physical health; Old age; Retirement; German Socio-Economic Panel Study.”
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“The results may relate to the wide variety of definitions of activity, ranging from exercise participation (Sherrill et al., 1998) to occupational (Ohayon et al., 2001), recreational (Janson et al., 2001), social (Habte-Gabr et al., 1991), and personal maintenance (Newman et al., 1997) activities.”
BackgroundProfile, comorbidity and impact of insomnia in the ibadan study of ageing
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The Comprehensive Dialysis Study (CDS)
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“2 (3) Quality of life KDQOL-36 symptoms/problems (4) KDQOL-36 effects of kidney disease (4) KDQOL-36 burden of kidney disease (4) KDQOL-SF cognitive function (4) Other symptoms/problems: Muscle weakness Headaches Postdialysis fatigue (HD patients) (5) Restless legs (6) Daytime sleepiness (7) Nocturnal sleep quantity a…”
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Jaiswal, S. J., Owens, R. L., & Malhotra, A. (2017) · Lung India · doi:10.4103/0970-2113.205331 · Cited by 54
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Effect of foot bathing on distal-proximal skin temperature gradient in elders
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MethodResultRole of stressful life events and menopausal stage in wellbeing and health
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“The importance of sufficient quantity and quality of sleep in older adults has been highlighted by numerous findings linking inadequate sleep to poor cardiovascular, immunological, cognitive, and affective health (Backhaus et al. 2002; Knutson et al. 2006; Newman et al. 1997).”
BackgroundSleep Complaints and Incident Disability in a Community-Based Cohort Study of Older Persons
Park, M. M., Buchman, A. S., Lim, A. S. P., Leurgans, S. E., & Bennett, D. A. (2013) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2012.12.023 · Cited by 44
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“By contrast, elderly women were twice as likely to report difficulty with sleep initiation compared to elderly men in the Cardiovascular Health Study [27].”
BackgroundResultSleep disturbance and its correlates among elderly Japanese
Ito, Y., Tamakoshi, A., Yamaki, K., Wakai, K., Kawamura, T., Takagi, K., Hayakawa, T., & Ohno, Y. (2000) · Archives of Gerontology and Geriatrics · doi:10.1016/s0167-4943(99)00054-0 · Cited by 44
“…presence of cardiovascular diseases (Newman et al., 1997), respiratory diseases (Habte-Gabr et al., 1991; Foley et al., 1995), stroke or arthritis (Newman et al., 1997), lower socioeconomic status (Habte-Gabr et al., 1991), limited physical functions (HabteGabr et al., 1991; Foley et al., 1995;…”
BackgroundResultInfluentialAssociated factors and psychotherapy on sleep disturbances in systemic lupus erythematosus
Kasitanon, N., Achsavalertsak, U., Maneeton, B., Wangkaew, S., Puntana, S., Sukitawut, W., & Louthrenoo, W. (2013) · Lupus · doi:10.1177/0961203313507355 · Cited by 44
Sleep in the Context of Healthy Aging and Psychiatric Syndromes
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“The most common complaints include frequent awakenings during the night, waking up too early, and difficulty falling asleep (Newman et al., 1997).”
BackgroundGenetic Association of Daytime Sleepiness and Depressive Symptoms in Elderly Men
Lessov‐Schlaggar, C. N., Bliwise, D. L., Krasnow, R. E., Swan, G. E., & Reed, T. (2008) · SLEEP · doi:10.5665/sleep/31.8.1111 · Cited by 41
Trojan, D. A., Kamińska, M., Bar‐Or, A., Benedetti, A., Lapierre, Y., Costa, D. D., Robinson, A. R., Cardoso, M., Schwartzman, K., & Kimoff, R. J. (2012) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2011.12.013 · Cited by 41
“arthritis, chronic pain) [34–36].”
Blay, S. L., Andreoli, S. B., & Gastal, F. L. (2007) · International Psychogeriatrics · doi:10.1017/s1041610207006308 · Cited by 41
“Some investigations, for example, have assessed sleep disturbance and a single specific medical disorder such as cardiovascular disease (Newman et al., 1997).”
BackgroundInfluentialPrevalence and risk factors for insomnia in community-dwelling elderly in northern Taiwan
Tsou, M.-T. (2013) · Journal of Clinical Gerontology and Geriatrics · doi:10.1016/j.jcgg.2013.02.002 · Cited by 40
Association between elder abuse and poor sleep: A cross-sectional study among rural older Malaysians
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“In the Cardiovascular Health Study including 5,888 whites and African Americans [6], daytime sleepiness was associated with CVD, and in an earlier study, difficulty falling asleep was associated with angina in the same population [7].”
BackgroundResultInfluentialRoy, A. N., & Smith, M. J. (2010) · Sleep Medicine · doi:10.1016/j.sleep.2009.09.012 · Cited by 38
“Studies have found the prevalence of insomnia to be higher in individuals with lower incomes [27–29] and in those with lower education [30,31].”
BackgroundHung, H., Yang, Y., Ou, H., Wu, J., Lu, F., & Chang, C. (2012) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2012.04423.x · Cited by 37
Insomnia symptoms and their correlates among the elderly in geriatric homes in Alexandria, Egypt
Makhlouf, M., Ayoub, A. I., & Abdel-Fattah, M. M. (2007) · Sleep And Breathing · doi:10.1007/s11325-006-0097-3 · Cited by 36
Hietapakka, L., Elovainio, M. J., Heponiemi, T., Presseau, J., Eccles, M., Aalto, A., Pekkarinen, L., Kuokkanen, L., & Sinervo, T. S. (2013) · Journal of Occupational Health Psychology · doi:10.1037/a0033990 · Cited by 41
Palliative care in patients with multiple sclerosis
Ben‐Zacharia, A. B., & LUBLIN, F. D. (2001) · Neurologic Clinics · doi:10.1016/s0733-8619(05)70048-7 · Cited by 37
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Ng, W. L., Shaw, J. E., & Peeters, A. (2017) · Sleep Medicine · doi:10.1016/j.sleep.2017.11.1132 · Cited by 35
Consequences of concern: ethics, social responsibility, and well‐being
Promislo, M. D., Giacalone, R. A., & Welch, J. (2012) · Business Ethics A European Review · doi:10.1111/j.1467-8608.2011.01648.x · Cited by 35
“1999), depression (Newman et al. 1997), and diabetes (Gottlieb et al.”
Assari, S., Lankarani, M. M., Kazemi‐Saleh, D., & Ahmadi, K. (2013) · Europe PMC (PubMed Central) · Cited by 35
Nakakubo, S., Doi, T., Makizako, H., Tsutsumimoto, K., Hotta, R., Ono, R., Suzuki, T., & Shimada, H. (2016) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2016.05.020 · Cited by 35
Li, L., Lu, L., Chai, J., Xiao, L., Ng, C. H., Ungvari, G. S., & Xiang, Y. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.00591 · Cited by 35
Ohayon, M. M. (2009) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2009.01.011 · Cited by 35
“, 2000) reaching up to 65% among older individuals (Ohayon et al., 2001; Newman et al., 1997).”
BackgroundMehra, R., Stone, K. L., Ancoli‐Israel, S., Litwack‐Harrison, S., Ensrud, K. E., & Redline, S. S. (2008) · SLEEP · doi:10.1093/sleep/31.11.1569 · Cited by 35
Gender and use of hypnotics or sedatives in old age: a nationwide register-based study
Johnell, K., & Fastbom, J. (2011) · International Journal of Clinical Pharmacy · doi:10.1007/s11096-011-9536-8 · Cited by 34
Falls in the Community-Dwelling Elderly With a History of Cancer
Spoelstra, S., Given, B. A., von Eye, A., & Given, C. W. (2010) · Cancer Nursing · doi:10.1097/ncc.0b013e3181bbbe8a · Cited by 34
Ensrud, K. E., BLACKWELL, T. L., Ancoli‐Israel, S., Redline, S. S., Yaffe, K. S., Diem, S. J., Claman, D. M., & Stone, K. L. (2006) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2006.00880.x · Cited by 34
“Epidemiological studies have found that 50% of elderly persons living in the community reported at least one sleep complaint, including difficulty sleeping, frequent awakenings, awaking too early, daytime sleepiness, and not feeling rested.(1,2) Depression and depressive symptoms have been associated with a greater li…”
BackgroundBetween Scylla and Charybdis: p53 links tumor suppression and aging
Campisi, J. (2002) · Mechanisms of Ageing and Development · doi:10.1016/s0047-6374(02)00006-4 · Cited by 33
Gschwind, Y. J., Bridenbaugh, S. A., Reinhard, S., Granacher, U., Monsch, A. U., & Kressig, R. W. (2017) · Aging Clinical and Experimental Research · doi:10.1007/s40520-016-0699-y · Cited by 33
Sleep disturbances in elderly subjects: an epidemiological survey in an Italian district
Bonanni, E., Tognoni, G., Maestri, M., Salvati, N., Fabbrini, M., Borghetti, D., Coscio, E. D., Choub, A., Sposìto, R., Pagni, C., et al. (2010) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.2010.01324.x · Cited by 33
“The association between cognitive dysfunction and excessive daytime sleepiness is in line with previous observations (31).”
ResultSun, K., Li, F., Qi, Y., Lin, D., Ren, M., Xu, M., Li, F., Yan, L., & Yan, L. (2015) · Endocrine · doi:10.1007/s12020-015-0772-x · Cited by 33
Sleep and physical functioning in family caregivers of older adults with memory impairment
Spira, A. P., Friedman, L., Beaudreau, S. A., Ancoli‐Israel, S., Hernandez, B., Sheikh, J. I., & Yesavage, J. A. (2009) · International Psychogeriatrics · doi:10.1017/s1041610209991153 · Cited by 31
“Self-reported poor sleep in older adults has been linked to impairment in physical functioning, as measured by the Medical Outcomes Study Short Form 36 (SF-36), and impairment in activities of daily living (ADLs), instrumental ADLs (IADLs) and ambulation (Ware and Sherbourne, 1992; Foley et al., 1995; Newman et al., 1…”
MethodResultUse of time in people with chronic obstructive pulmonary disease – a systematic review
Hunt, T., Madigan, S., Williams, M., & Olds, T. (2014) · International Journal of COPD · doi:10.2147/copd.s74298 · Cited by 33
“46,47 People with COPD are likely to have all three of these factors so it is perhaps unsurprising that we identified considerably lower median sleep durations (290 min/d), 47 and episodes of night-time awakenings and daytime napping, 35 than comparable age-matched adults.”
Scott, A. J., Rowse, G., & Webb, T. L. (2017) · PLOS ONE · doi:10.1371/journal.pone.0186233 · Cited by 30
First night of CPAP: impact on memory consolidation attention and subjective experience
Djonlagic, I. E., Guo, M., Matteis, P., Carusona, A. L., Stickgold, R., & Malhotra, A. (2015) · Sleep Medicine · doi:10.1016/j.sleep.2015.01.017 · Cited by 31
“Disorders of breathing during sleep are a major health problem; in particular, obstructive sleep apnea (OSA) has been associated with important health consequences including an increased risk for cardiovascular [1–6] and cerebrovascular disease [7,8], mortality [5,9–14], and cognitive impairment, independent of daytim…”
BackgroundSerdarevic, M., Osborne, V., Striley, C. W., & Cottler, L. B. (2017) · Sleep Health · doi:10.1016/j.sleh.2017.07.007 · Cited by 30
Low-dose doxepin for the treatment of insomnia: emerging data
Goforth, H. (2009) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656560903005587 · Cited by 27
“The pattern of remission has also been noted in the Cardiovascular Health Study of 2005 [6].”
MethodFall-related functional impairments in patients with neurological gait disorder
Ehrhardt, A., Hostettler, P., Widmer, L. A., Reuter, K., Petersen, J. A., Straumann, D., & Filli, L. (2020) · Scientific Reports · doi:10.1038/s41598-020-77973-4 · Cited by 28
Multidimensional sleep health and subsequent health-care costs and utilization in older women.
Ensrud, K., Kats, A. M., Schousboe, J., Langsetmo, L., Vo, T., Blackwell, T., Buysse, D. J., Ancoli-Israel, S., & Stone, K. (2019) · Sleep · doi:10.1093/sleep/zsz230 · Cited by 25
“Sleep complaints, including difficulty falling asleep, frequent awakening, awaking too early, daytime sleepiness, and not feeling rested, are increasingly common with advancing age [1, 2].”
BackgroundFeasibility of the Epworth Sleepiness Scale in a sample of geriatric in-hospital patients.
Frohnhofen, H., Popp, R., Willmann, V., Heuer, H.-C., & Firat, A. (2009) · PubMed · Cited by 27
Factors Associated with Insomnia among Elderly Patients Attending a Geriatric Centre in Nigeria
Ogunbode, A. M., Adebusoye, L. A., Olowookere, O. O., Owolabi, M. O., & Ogunniyi, A. O. (2014) · Current Gerontology and Geriatrics Research · doi:10.1155/2014/780535 · Cited by 27
Parker, K. P., & Dunbar, S. B. (2002) · The Journal of Cardiovascular Nursing · doi:10.1097/00005082-200210000-00004 · Cited by 27
Okunowo, O., Orimoloye, H. T., Bakre, S. A., Njesada, N. S., & Solomon, A. (2019) · Sleep Health · doi:10.1016/j.sleh.2019.05.003 · Cited by 25
Physical functioning among mid-life women: Associations with trajectory of depressive symptoms
Tomey, K., Sowers, M. F., Harlow, S. D., Jannausch, M. L., Zheng, H. T., & Bromberger, J. T. (2010) · Social Science & Medicine · doi:10.1016/j.socscimed.2010.06.037 · Cited by 26
The Contribution of Heart Failure to Sleep Disturbances and Depressive Symptoms in Older Adults
Johansson, P., Riegel, B. J., Svensson, E., Broström, A., Alehagen, U., Dahlström, U., & Jaarsma, T. (2012) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988712458366 · Cited by 26
“Despite this, pain is seldom included as a variable in studies investigating correlates or predictors of sleep in community-dwelling elderly patients.(14,37,38) In the present study, pain during the night was associated with sleep disturbances and depressive symptoms, and the magnitude of the relationship was the same…”
BackgroundKutner, N. G., Bliwise, D. L., & Zhang, R. V. (2004) · Journal of Health and Social Behavior · doi:10.1177/002214650404500107 · Cited by 26
Metadata
- Authors
- Newman, A. B., Enright, P. L., Manolio, T. A., Haponik, E. F., Wahl, P. W., & On behalf of the Cardiovascular Health Study Research Group
- Affiliations
- University of Pittsburgh (US)
- University of Arizona (US)
- National Heart, Lung, and Blood Institute (US)
- Atrium Health Wake Forest Baptist (US)
- University of Washington (US)
- Corresponding author
- Newman, Anne B.
- Venue
- Journal of the American Geriatrics Society
- Publisher
- Wiley
- Published
- 1997-01
- Volume
- 45
- Issue
- 1
- Pages
- 1-7
- ISSN
- 0002-8614 (ISSN-L)
- 1532-5415
- OpenAlex
- W1980398586
- Cited by
- 365
- References
- 46
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 7 · 2023: 4 · 2022: 8 · 2021: 9 · 2020: 12 · 2019: 12 · 2018: 7 · 2017: 17 · 2016: 7 · 2015: 14 · 2014: 16 · 2013: 18 · 2012: 16
- FWCI
- 16.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of the American Geriatrics Society (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (n01hc085079-024)
- National Heart, Lung, and Blood Institute (N01-HC85079)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Physiology (medical) › Obstructive Sleep Apnea Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Keywords
- sleep disorders, older adults, cardiovascular disease, daytime sleepiness, difficulty falling asleep, depression, benzodiazepines, angina pectoris, activities of daily living, psychosocial factors, sex differences, cardiovascular risk factors, Cardiovascular Health Study
- MeSH terms
- Aged, Aged, 80 and over, Cardiovascular Diseases, Cross-Sectional Studies, Depression, Female, Health Surveys, Humans, Male, Psychotropic Drugs, Surveys and Questionnaires, Random Allocation, Risk Factors, Sex Factors, Sleep Wake Disorders, Social Support, United States, Geriatric Assessment, Prevalence
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