CoChat
Sign Up
Cited by 55Cardiovascular Syncope and Autonomic DisordersCardiac pacing and defibrillation studiesCardiac electrophysiology and arrhythmias

Incidence and predictors of syncope in paced patients with sick sinus syndrome

SGARBOSSA, ELENA B., PINSKI, SERGIO L., JAEGER, FREDRICK J., TROHMAN, RICHARD G., MALONEY, JAMES D.·1992·Pacing and Clinical Electrophysiology
DOI 10.1111/j.1540-8159.1992.tb03021.x
Open this paper in CoChat — free account

Abstract

UNLABELLED: In spite of a normal pacemaker function, syncope still occurs in some patients with sick sinus syndrome (SSS). Causes often remain unknown. To identify predictors and etiologies of this bothersome symptom, we studied 507 patients who received atrial, ventricular, and dual-chamber pacemakers for SSS. During a mean follow-up of 62 +/- 38 months, actuarial incidence of syncope was 3% at 1 year, 8% at 5 years, and 13% at 10 years. Causes were vasovagal (18%), orthostatic hypotension (25.5%), rapid atrial tachyarrhythmias (11.5%), ventricular tachycardia (5%), acute myocardial ischemia (2.5%), and pacemaker/lead malfunction (6.5%). In 13 patients (29.5%), syncope remained unexplained. The only preimplant predictor for syncope was syncope as primary indication for pacemaker implant. Electrocardiographic correlation with bradycardia was not a predictor of relief of syncope during the follow-up. IN CONCLUSION: (1) syncope in paced patients with SSS has multiple etiologies and may be multifactorial; (2) the only predictor of syncope after pacemaker implant is the occurrence of preimplant syncope as the main indication for pacing; (3) extensive Holter monitoring is not useful to document bradycardiac origin of syncope nor to predict its recurrence; (4) SSS probably overlaps with other entities such as autonomic dysfunction, vasovagal syncope, carotid sinus hypersensitivity, and venous pooling, which would provide an explanation for recurrent syncope in patients with normal pacemaker function.

Integrity signals

Registry

Crossref · 10.1111/j.1540-8159.1992.tb03021.x

Cites

27 of 27 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • In the absence of correlation between symptoms and ECG, despite adequate pacing, syncope recurs in approximately 15-28% of patients with sinus node disease at 5 years.

    “In the absence of the above situations, despite adequate pacing, syncope recurs in approximately 15-28% of patients at 5 years 339-341 (see Supplementary Data Table 9 ).”

    From 2018 ESC Guidelines for the diagnosis and management of syncope (2018) · cites this paper as [339]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
SGARBOSSA, E. B., PINSKI, S. L., JAEGER, F. J., TROHMAN, R. G., & MALONEY, J. D.
Affiliations
Cleveland Clinic (US)
Corresponding author
MALONEY, JAMES D.
ORCID
TROHMAN, RICHARD G.
Venue
Pacing and Clinical Electrophysiology
Publisher
Wiley
Published
1992-11
Volume
15
Issue
11
Pages
2055-2060
ISSN
  • 0147-8389 (ISSN-L)
  • 1540-8159
DOI
10.1111/j.1540-8159.1992.tb03021.x
OpenAlex
W2054229313
Cited by
55
References
27
Citations by year
2023: 1 · 2022: 1 · 2021: 1 · 2020: 2 · 2019: 3 · 2018: 4 · 2016: 1 · 2015: 3 · 2014: 5 · 2013: 1
FWCI
2.44
Type
journal article
Language
en
Open access
closed
Licence
onlinelibrary.wiley.com/termsAndConditions#vor (vor, 4989 d)
Locations
  • Pacing and Clinical Electrophysiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Keywords
syncope, sick sinus syndrome, pacemaker patients, incidence, predictive factors, vasovagal syncope, orthostatic hypotension, ventricular tachycardia, pacemaker malfunction, carotid sinus hypersensitivity, autonomic dysfunction, venous pooling, bradycardia
MeSH terms
Actuarial Analysis, Aged, Cardiac Pacing, Artificial, Female, Follow-Up Studies, Humans, Male, Pacemaker, Artificial, Risk Factors, Sick Sinus Syndrome, Syncope, Time Factors, Electrocardiography, Ambulatory, Incidence

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review