Cited by 124Medicinal Plants and Bioactive CompoundsPhytochemicals and Medicinal PlantsMedicinal Plant Extracts Effects

Rhodiola rosea : A Versatile Adaptogen

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Khanum, Farhath, Bawa, Amarinder Singh, Singh, Brahm·2005·Comprehensive Reviews in Food Science and Food Safety

Abstract

Rhodiola rosea (rose root) belonging to the family Crassulaceae is a popular medicinal plant in Russia, Scandinavia, and many other countries. Extracts of the roots of this plant have been found to favorably affect a number of physiological functions including neurotransmitter levels, central nervous system activity, and cardiovascular function. It is being used to stimulate the nervous system, decrease depression, enhance work performance, eliminate fatigue, and prevent high-altitude sickness. Most of these effects have been ascribed to constituents such as salidroside (rhodioloside), rosavins, and p-tyrosol. It has also been found to be a strong antioxidant and anticarcinogen due to the presence of several phenolic compounds. Adaptogens are plant extracts that allow an organism to counteract adverse physical, chemical, and biological stressors by generating nonspecific resistance. Adaptogens are known to increase the availability of energy during the day, reduce stressed feelings, increase endurance, and increase mental alertness. This multipurpose medicinal plant (R. rosea), with adaptogenic properties that increase the body's nonspecific resistance and normalize functions, has been traditionally grown and used in Russia and Mongolia. Due to increasing consumer demands toward natural health products and the growing interests in the secondary metabolites of plants and their application in biotechnology and therapy, much focus has been put on the rose root and its medical properties. The rose root imparts normalizing influences on adverse physical, chemical, and biological disturbances but is otherwise innocuous. In India, the plant has been growing wild in the high altitudes of the Himalayas. The Defence Research and Development Organization in India has taken on the responsibilities of its conservation, as well as the development of multiple management practices and the development of health foods, supplements, and nutraceuticals in India.

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Crossref · 10.1111/j.1541-4337.2005.tb00073.x

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  • The main phenylethanol derivatives of Rhodiola rosea are salidroside, para-tyrosol, and phenylpropanoid-rosavin, and these are responsible for its adaptogenic and ergogenic effects.

    “The main phenylethanol derivatives are salidroside (rhodioloside), para-tyrosol, and phenylpropanoid-rosavin. These are also responsible for the adaptogenic and ergogenic effects of Rhodiola rosea [8,73,75].”

    From Plant Adaptogens—History and Future Perspectives (2021) · cites this paper as [75]

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Research works printed but not linked: 7

  1. Gerasimova HD. 1970. Effect of Rhodiola rosea extract on ovarian functional ac- tivity. Proc of Scientific Conference on Endocrinology and Gynecology; Sverd- lovsk, Russia; 1970 Sept 15-6. Siberia, Russia: Siberian Branch of the Russian Academy of Sciences. p 46-8.
  2. Krasik ED, Morozova ES, Petrova KP, Ragulina GA, Shemetova LA, Shuvaev VP. 1970. Therapy of asthenic conditions: clinical perspectives of application of Rhodiola rosea extract (golden root). In: Proceedings modern problems in psycho- pharmacology. Kemerovo, Russia; 27-9 May 1070; Siberian Branch of Russian Academy of Sciences. p 298-330.
  3. Krylov GV. 1969. Herbs for Life. Novosibirsk, Russia: Academic Press. p 264.
  4. Kurkin VA, Zapesochnaya GG. 1985. Chemical composition and pharmacological characteristics of Rhodiola rosea [review]. J Med Plants (Moscow) 1985:1231- 445.
  5. Kurkin VA, Zapesochnaya GG. 1986. Chemical composition and pharmacological properties of Rhodiola rosea. Chem Pharm J (Moscow) 20(10):1231-44.
  6. Saratikov AS, Krasnov EA. 1987. Rhodiola rosea is a valuable medicinal plant (Golden Root). Tomsk, Russia: Tomsk State Univ. Press.
  7. Stancheva SL, Mosharrof A. 1987. Effect of the extract of Rhodiola rosea L. on the content of the brain biogenic monoamines. Med Physiol Comp Rend Acad Bulg Sci 40(6):85-7.

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Authors
Khanum, F., Bawa, A. S., & Singh, B.
Affiliations
Defence Food Research Laboratory (IN)
Venue
Comprehensive Reviews in Food Science and Food Safety
Publisher
Wiley
Published
2005-07
Volume
4
Issue
3
Pages
55-62
ISSN
1541-4337 (ISSN-L)
OpenAlex
W2071960728
Cited by
124
References
20
Citations by year
2026: 5 · 2025: 7 · 2024: 5 · 2023: 14 · 2022: 7 · 2021: 7 · 2020: 8 · 2019: 5 · 2018: 5 · 2017: 6 · 2016: 6 · 2015: 6 · 2014: 6 · 2013: 8 · 2012: 3
FWCI
1.12
Type
journal article
Language
en
Open access
Locations
  • Comprehensive Reviews in Food Science and Food Safety (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Medicinal Plants and Bioactive Compounds
  • Health Sciences › Medicine › Complementary and alternative medicine › Phytochemicals and Medicinal Plants
  • Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plant Extracts Effects
Keywords
Rhodiola rosea, adaptogens, medicinal plants, salidroside, rosavin, p-tyrosol, antioxidant activity, anticarcinogenic activity, phenolic compounds, stress tolerance, fatigue, depression, altitude sickness, nutraceuticals, plant conservation, Himalaya

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