Pneumocystis Dihydropteroate Synthase Mutations in Patients with Pneumocystis Pneumonia Who Are Newly Diagnosed with HIV Infection
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The presence of DHPS mutations in patients without prior TMP-SMX or dapsone use for PCP prophylaxis, the absence of similar mutations in Pneumocystis isolated from other mammalian species, and the impact of geography on DHPS genotype have substantial implications for disease transmission (i.e., person-to-person transmission).
“The presence of DHPS mutations in patients without prior TMP-SMX or dapsone use for PCP prophylaxis, the absence of similar mutations in Pneumocystis isolated from other mammalian species, and the impact of geography on DHPS genotype have substantial implications for disease transmission (i.e., person-to-person transmission) that are beyond the scope of this review (32–35).”
From Dihydropteroate Synthase Gene Mutations in<i>Pneumocystis</i>and Sulfa Resistance (2004) · cites this paper as [35]
Cites
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Self-citationNew Insights Into Transmission, Diagnosis, and Drug Treatment of Pneumocystis carinii Pneumonia
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Self-citationNavin, T. R., Beard, C. B., Huang, L., del Rio, C., Lee, S., Pieniazek, N. J., Carter, J. L., Le, T., Hightower, A., & Rimland, D. (2001) · The Lancet · doi:10.1016/s0140-6736(01)05705-1 · Cited by 117 · see citing works
Self-citationUpdate on the epidemiology and transmission of Pneumocystis carinii
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Dihydropteroate Synthase Gene Mutations in<i>Pneumocystis</i>and Sulfa Resistance
Huang, L., Crothers, K., Atzori, C., Benfield, T., Miller, R., Rabodonirina, M., & Helweg-Larsen, J. (2004) · Emerging Infectious Diseases · doi:10.3201/eid1010.030994 · Cited by 131 · see citing works
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- Authors
- CROTHERS, K., HUANG, L., MORRIS, A., FOX, M., GRONER, G., TURNER, J. R., MERRIFIELD, C., EISER, S., FRIEDLY, J., GRAVARI, E., ZUCCHI, P., & BEARD, C. B.
- Affiliations
- San Francisco General Hospital (US)
- University of Southern California (US)
- Centers for Disease Control and Prevention (US)
- Corresponding author
- HUANG, LAURENCE
- Venue
- Journal of Eukaryotic Microbiology
- Publisher
- Wiley
- Published
- 2003-07
- Volume
- 50
- Issue
- s1
- Pages
- 609-610
- ISSN
- 1066-5234 (ISSN-L)
- 1550-7408
- OpenAlex
- W2159668271
- Cited by
- 12
- References
- 14
- FWCI
- 1.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Eukaryotic Microbiology (publishedVersion)
- PubMed (publishedVersion)
- BioOne Complete (BioOne) (submittedVersion)
- Funders
- National Institutes of Health
- National Heart, Lung, and Blood Institute (K23HL072117, 1K23HL72117-01, K23HL072837)
- Topics
- Health Sciences › Medicine › Epidemiology › Pneumocystis jirovecii pneumonia detection and treatment
- Health Sciences › Medicine › Epidemiology › Pneumonia and Respiratory Infections
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS drug development and treatment
- Keywords
- Pneumocystis jirovecii, dihydropteroate synthase, Pneumocystis carinii pneumonia, HIV infection, drug resistance, newly diagnosed HIV, antifolate resistance
- MeSH terms
- Antifungal Agents, Dihydropteroate Synthase, Genotype, Humans, Mutation, Pneumocystis, Pneumonia, Pneumocystis, Retrospective Studies, AIDS-Related Opportunistic Infections
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