The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
12‐Month comorbidity patterns and associated factors in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project
Abstract
Objective: Comorbidity patterns of 12‐month mood, anxiety and alcohol disorders and socio‐demographic factors associated with comorbidity were studied among the general population of six European countries. Method: Data were derived from the European Study of the Epidemiology of Mental Disorders (ESEMeD), a cross‐sectional psychiatric epidemiological study in a representative sample of adults aged 18 years or older in Belgium, France, Germany, Italy, the Netherlands and Spain. The diagnostic instrument used was the Composite International Diagnostic Interview (WMH‐CIDI). Data are based on 21 425 completed interviews. Results: In general, high associations were found within the separate anxiety disorders and between mood and anxiety disorders. Lowest comorbidity associations were found for specific phobia and alcohol abuse—the disorders with the least functional disabilities. Comorbidity patterns were consistent cross‐nationally. Associated factors for comorbidity of mood and anxiety disorders were female gender, younger age, lower educational level, higher degree of urbanicity, not living with a partner and unemployment. Only younger people were at greater risk for comorbidity of alcohol disorder with mood, anxiety disorders or both. Conclusion: High levels of comorbidity are found in the general population. Comorbidity is more common in specific groups. To reduce psychiatric burden, early intervention in populations with a primary disorder is important to prevent comorbidity.
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“Conversely, among individuals with a lifetime drug use disorder, 28.3% also had an anxiety disorder, 26.4% had a mood disorder, and 6.8% had schizophrenia.”
From Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention (2023) · cites this paper as [125]
In the citing paper
“and that in persons with panic disorder was 35.8% (OR=2.9) 125 .”
From Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention (2023) · cites this paper as [125]
In the citing paper
“Analogous findings have been docu mented in other US large epidemiological studies, including the National Comorbidity Survey 126 and the National Epidemiologic Survey on Alcohol and Related Conditions 126,127 , as well as in stud ies from other countries 125- 128 .”
From Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention (2023) · cites this paper as [125]
In the citing paper
“that in people with schizophrenia or schizophreniform disorder was 47.0% (OR=4.6)”
From Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention (2023) · cites this paper as [125]
In the citing paper
“prevalence of SUDs in individuals with a lifetime diagnosis of bi polar disorder was 56.1% (odds ratio, OR=6.6)”
From Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention (2023) · cites this paper as [125]
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“Lifetime prevalence for MDD and dysthymia in Europe are 12.8% and 4.1%, respectively, and point prevalence of MDD and dysthymia in different European countries varies between 1.1 and 3.9% (Alonso et al., 2004a,b).”
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“There is a high prevalence of substance abuse problems among people with psychiatric illness and a high prevalence of psychiatric problems among people with substance abuse (Alonso et al., 2004; Regier et al., 1990).”
Backgroundfor the PREMA-study group, Lukaschek, K., Mergenthal, K., Heider, D., Hanke, A., Munski, K., Moschner, A., Emig, M., van den Akker, M., Zapf, A., et al. (2019) · Trials · doi:10.1186/s13063-019-3751-3 · Cited by 8
Prise en charge de la dépression en soins primaires : revue et perspectives
Rotgé, J., Tignol, J.-P., & Aouizerate, B. (2007) · L Encéphale · doi:10.1016/s0013-7006(07)92052-7 · Cited by 8
Prevalence of mental disorders in a Greek island.
Stylianidis, S., Pantelidou, S., Chondros, P., Roelandt, J.-L., & Barbato, A. (2014) · PubMed · Cited by 7
Social network as predictor for onset of alcohol use disorder: A prospective cohort study
Mikkelsen, S. S., Tolstrup, J. S., Becker, U., Mortensen, E. L., & Flensborg‐Madsen, T. (2015) · Comprehensive Psychiatry · doi:10.1016/j.comppsych.2015.05.005 · Cited by 7
Millet, Gerard, Liard, Goni, & Crochard, A. (2012) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s34132 · Cited by 7
“For example, in the European Study of the Epidemiology of Mental Disorders in six European countries, 53% of individuals with major depressive disorder, 69% of those with generalized anxiety disorder, and 64% of those with panic disorder presented with another mood or anxiety disorder.(3) Similar findings have been re…”
Metzner, F., Wlodarczyk, O., & Pawils, S. (2017) · Journal of Social Service Research · doi:10.1080/01488376.2017.1282391 · Cited by 7
Potential Use of Modulators of Oxidative Stress as Add-on Therapy in Patients with Anxiety Disorders
Boldrini, P., Fusco, A., Nicoletti, F., Badiani, A., & Saso, L. (2017) · Current Drug Targets · doi:10.2174/1389450118666170425153356 · Cited by 7
“disorder [6] and also with chronic medical conditions, such as diabetes [7],chronic obstructive pulmonary disease [8], thyroid dysfunction [9] and coronary artery disease [10].”
BackgroundPredicting the course of anxiety disorders: The role of biological parameters
Bosman, R. C., van Balkom, A. J. L. M., Rhebergen, D., van Hemert, A. M., Schoevers, R. A., Penninx, B. W. J. H., & Batelaan, N. M. (2020) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2020.109924 · Cited by 8
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Prise en charge de la comorbidité du trouble bipolaire avec l’alcoolodépendance
Brousse, G., Garay, R. P., & Benyamina, A. (2008) · La Presse Médicale · doi:10.1016/j.lpm.2007.09.020 · Cited by 6
A Study of Patients who go to a Psychology Clinic Seeking Treatment
Estupiñá, F. J., Labrador, F. J., & García‐Vera, M. P. (2012) · The Spanish Journal of Psychology · doi:10.5209/rev_sjop.2012.v15.n1.37334 · Cited by 5
“…focus on “pure” issues (only one diagnosis), it is more frequent in everyday clinical practice for various problems to occur at once (Goldfried & Wolfe, 1996; Seligman, 1995), though this tendency varies widely across different diagnostic categories and demographic profiles (Alonso et al., 2004).”
BackgroundPharmacotherapy for anxiety disorders and comorbid alcohol dependency
Wilson, D., Ipser, J., & Stein, D. J. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007505 · Cited by 5
Ansiedade e Depressão em Pacientes Migranosos
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Which factors influence psychiatric diagnosing in substance abuse treatment?
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“Population studies indicate that psychiatric disorders and substance use disorders (SUDs) appear simultaneously among 30 – 40% of those with alcohol use disorders, and 40 – 50% of those with drug use disorders [3-8].”
BackgroundResultInfluentialNeurotic, stress-related and somatoform disorders
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Les dépressions sévères : quels concepts ? quels critères ?
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Börsbo, B. (2008) · Cited by 4
Are Anxiety and Depression Two Sides of the Same Coin?
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Epidemiologie der Angststörungen
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Self-citationSymptoms of depression and post-traumatic stress in a group of lightning strike victims
Yrondi, A., DerKasbarian, R., Gallini, A., Max, V., Pauron, C., Joubin, A., Laguerre, J., Virenque, C., & Birmes, P. J. (2019) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2019.03.012 · Cited by 3
Factors associated with prolonging psychological treatment for anxiety disorders.
Bernaldo-de-Quirós, M., Labrador, F., García-Fernández, G., Fernández-Arias, I., Estupiñá, F., & Labrador-Méndez, M. (2015) · Psicothema · doi:10.7334/psicothema2014.264 · Cited by 3
“Both epidemiological (Alonso et al., 2004) and clinical studies (Brown, Campbell, Lehman, Grisham, & Mancill, 2001) report high rates of comorbidity in patients diagnosed with AD.”
BackgroundDEPRESSION IN PRIMARY CARE: PREVALENCE, DIAGNOSIS AND TREATMENT
Vindel, A. C., Salguero, J. M., Wood, C. M., Dongil, E., & Latorre, J. M. (2012) · Cited by 3
Abbasi-Ghahramanloo, A., Bahadori, M., Azad, E., Dopeykar, N., Mahdizadeh, P., Vahedian‐Azimi, A., & Amini, H. (2021) · BMC Psychiatry · doi:10.1186/s12888-021-03537-z · Cited by 3
“Comorbidity between different mental disorders is extensive with up to 50% of those who have one mental disorder also having at least one additional comorbid mental disorder [5, 8, 18].”
BackgroundSocial phobia with sudden onset—Post-panic social phobia?
Kristensen, A. S., Mortensen, E. L., & Mors, O. N. (2007) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2007.07.002 · Cited by 3
“Large comorbidity between PD and SP has been found in both clinical samples (Brown, Campbell, Lehman, Grisham, & Mancill, 2001; Rodriguez et al., 2004) and epidemiological studies (Alonso et al., 2004; Goodwin & Hamilton, 2001; Schneier, Johnson, Hornig, Liebowitz, & Weissman, 1992).”
BackgroundMétodos de investigación sobre daños en la población relacionados con el alcohol
Indave, B. I., Sordo, L., Pulido, J., Vallejo, F., Sarasa‐Renedo, A., & Bravo, M. J. (2014) · Revista Española de Salud Pública · doi:10.4321/s1135-57272014000400003 · Cited by 1
Lima, M. D. R. D. A., da Cruz, R. B., & Rafael, M. (2015) · REOP - Revista Española de Orientación y Psicopedagogía · doi:10.5944/reop.vol.25.num.3.2014.13855 · Cited by 2
Gale, C. K. (2007) · Evidence-Based Mental Health · doi:10.1136/ebmh.10.2.45 · Cited by 2
Metadata
- Authors
- The ESEMeD/MHEDEA 2000 investigators, Alonso, J., Angermeyer, M. C., Bernert, S., Bruffaerts, R., Brugha, T. S., Bryson, H., de Girolamo, G., de Graaf, R., Demyttenaere, K., Gasquet, I., Haro, J. M., Katz, S. J., Kessler, R. C., Kovess, V., Lépine, J. P., Ormel, J., Polidori, G., Russo, L. J., Vilagut, G., Almansa, J., Arbabzadeh‐Bouchez, S., Autonell, J., Bernal, M., Buist‐Bouwman, M. A., Codony, M., Domingo‐Salvany, A., Ferrer, M., Joo, S. S., Martínez‐Alonso, M., Matschinger, H., Mazzi, F., Morgan, Z., Morosini, P., Palacín, C., Romera, B., Taub, N., & Vollebergh, W. A. M.
- Affiliations
- University of Leicester (GB)
- Leipzig University (DE)
- KU Leuven (BE)
- GlaxoSmithKline (United Kingdom) (GB)
- Centro San Giovanni di Dio Fatebenefratelli (IT)
- Hôpital Paul-Brousse (FR)
- Universitat de Barcelona (ES)
- Harvard University (US)
- Mutuelle Générale de l'Éducation Nationale (FR)
- University of Groningen (NL)
- Istituto Superiore di Sanità (IT)
- Institut Municipal d'Assistència Sanitària (ES)
- Assistance Publique – Hôpitaux de Paris (FR)
- Trimbos Institute (NL)
- University of Modena and Reggio Emilia (IT)
- ORCID
- Venue
- Acta Psychiatrica Scandinavica
- Publisher
- Wiley
- Published
- 2004-06
- Volume
- 109
- Issue
- s420
- Pages
- 28-37
- ISSN
- 0001-690X (ISSN-L)
- 1600-0447
- OpenAlex
- W1978533844
- Cited by
- 242
- References
- 35
- Citations by year
- 2025: 2 · 2024: 1 · 2023: 5 · 2022: 7 · 2021: 5 · 2020: 8 · 2019: 7 · 2018: 10 · 2017: 15 · 2016: 9 · 2015: 12 · 2014: 23 · 2013: 14 · 2012: 12
- FWCI
- 21.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Psychiatrica Scandinavica (publishedVersion)
- PubMed (publishedVersion)
- Leicester Research Archive (University of Leicester) (submittedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
- Radboud Repository (Radboud University) (submittedVersion)
- Funders
- GlaxoSmithKline
- European Commission
- Instituto de Salud Carlos III
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- psychiatric comorbidity, mood disorders, anxiety disorders, alcoholism, specific phobia, alcohol abuse, sociodemographic risk factors, cross-national comparison, mental health burden, early intervention
- MeSH terms
- Adolescent, Adult, Aged, Alcoholism, Anxiety, Cross-Sectional Studies, Demography, Europe, Female, Humans, International Cooperation, Male, Middle Aged, Psychology, Comorbidity, Prevalence, Mood Disorders
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