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Cited by 47Posttraumatic Stress Disorder ResearchPersonality Disorders and PsychopathologyPsychoanalysis and Psychopathology Research

The 10-year course of PTSD in borderline patients and axis II comparison subjects: The 10-year course of PTSD in BPD patients

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Zanarini, M. C., Hörz, S., Frankenburg, F. R., Weingeroff, J., Reich, D. B., Fitzmaurice, G.·2011·Acta Psychiatrica Scandinavica
DOI 10.1111/j.1600-0447.2011.01717.xPMC PMC3203727
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Abstract

OBJECTIVE: The first objective is to detail the prevalence of post-traumatic stress disorder (PTSD) over a decade of follow-up for those in both study groups. The second is to determine time-to-remission, recurrence, and new onset of PTSD, and the third is to assess the relationship between sexual adversity and the likelihood of remission and recurrence of PTSD. METHOD: The SCID I was administered to 290 borderline in-patients and 72 axis II comparison subjects during their index admission and re-administered at five contiguous 2-year follow-up periods. RESULTS: The prevalence of PTSD declined significantly over time for patients with borderline personality (BPD) (61%). Over 85% of borderline patients meeting criteria for PTSD at baseline experienced a remission by the time of the 10-year follow-up. Recurrences (40%) and new onsets (27%) were less common. A childhood history of sexual abuse significantly decreased the likelihood of remission from PTSD, and an adult history of sexual assault significantly increased the likelihood of a recurrence of PTSD. CONCLUSION: Taken together, the results of this study suggest that PTSD is not a chronic disorder for the majority of borderline patients. They also suggest a strong relationship between sexual adversity and the course of PTSD among patients with BPD.

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  • A 10-year follow-up of adults diagnosed with BPD found that most (85%) who had been initially diagnosed with PTSD were in remission from PTSD but continued to meet criteria for BPD.

    “A 10-year follow-up of adults diagnosed with BPD found that most (85%) who had been initially diagnosed with PTSD were in remission from PTSD but continued to meet criteria for BPD [192].”

    From Complex PTSD and borderline personality disorder (2021) · cites this paper as [192]

    The Results report that an estimated 87% of patients with BPD and PTSD at baseline experienced PTSD remission by the 10-year follow-up, supporting the claim’s approximate 85% figure. The paper does not establish that those patients continued to meet BPD criteria, and it reports that 40% of PTSD remitters later had a recurrence; remission by follow-up does not necessarily mean they were still in remission at year ten. (LLM, conf=0.88)

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  • More than one in four of the BPD cases had a new diagnosis of PTSD over the 10-year period, most often following a sexual assault.

    “More than one in four of the BPD cases had a new diagnosis of PTSD over the 10-year period, most often following a sexual assault [192].”

    From Complex PTSD and borderline personality disorder (2021) · cites this paper as [192]

    The Results report new-onset PTSD in an estimated 27% of BPD patients who did not have PTSD at baseline, not 27% of all BPD cases. They do not show that new diagnoses most often followed a sexual assault: 20 of the 30 new-onset cases were delayed onsets attributed to earlier trauma, while six patients reported rape during follow-up. No page numbers are provided in our copy. (LLM, conf=0.88)

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Research works printed but not linked: 1

  1. [26]Herman JL Van Der Kolk BA van der Kolk BA Traumatic antecedents of borderline personality disorder Psychological Trauma 1987 Washington DC American Psychiatric Press 111 126

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Authors
Zanarini, M. C., Hörz, S., Frankenburg, F. R., Weingeroff, J., Reich, D. B., & Fitzmaurice, G.
Affiliations
  • Harvard University (US)
  • Boston University (US)
  • McLean Hospital (US)
Corresponding author
Zanarini, M. C.
ORCID
Venue
Acta Psychiatrica Scandinavica
Publisher
Wiley
Published
2011-05-12
Volume
124
Issue
5
Pages
349-356
ISSN
0001-690X (ISSN-L)
DOI
10.1111/j.1600-0447.2011.01717.x
PMC
PMC3203727
OpenAlex
W1700012628
Cited by
47
References
34
Citations by year
2026: 2 · 2025: 1 · 2024: 5 · 2023: 5 · 2022: 1 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 5 · 2017: 4 · 2016: 3 · 2015: 4 · 2014: 5 · 2013: 4 · 2012: 2
FWCI
3.79
Type
journal article
Language
en
Open access
Licence
doi.wiley.com/10.1002/tdm_license_1.1 (tdm, 1573 d)
Locations
  • Acta Psychiatrica Scandinavica (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health
  • National Institute of Mental Health (MH-62169, R29MH047588, R01MH062169, MH-47588)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
  • Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
Keywords
post-traumatic stress disorder, borderline personality disorder, PTSD remission, PTSD prevalence, sexual abuse, child sexual abuse, adult sexual assault, long-term follow-up
MeSH terms
Adult, Borderline Personality Disorder, Female, Humans, Longitudinal Studies, Male, Personality Disorders, Psychiatric Status Rating Scales, Recurrence, Remission Induction, Stress Disorders, Post-Traumatic, Prevalence, Case-Control Studies

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