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The Role of Apoptosis Signal-regulating Kinase 1 in Lymphotoxin-β Receptor-mediated Cell Death

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TNF受容体(TNFR)関連因子(TRAF)3はTRAF結合性TNFRによる非定型的NFκB経路のTRAF2/5介在性活性化の阻害物質として働く

Hauer, J., Püschner, S., Ramakrishnan, P., Simon, U., Bongers, M., Federle, C., & Engelmann, H. (2005) · Cited by 58 · see citing works

A unique T cell subset described as CD4loCD40+ T cells (TCD40) in human type 1 diabetes

Waid, D., Wagner, R., Putnam, A. L., Vaitaitis, G. M., Pennock, N. D., Calverley, D. C., Gottlieb, P. A., & Wagner, D. H. (2007) · Clinical Immunology · doi:10.1016/j.clim.2007.05.003 · Cited by 57 · see citing works

CD40 on NOD CD4 T cells contributes to their activation and pathogenicity

Baker, R. L., Wagner, D. H., & HASKINS, K. M. (2008) · Journal of Autoimmunity · doi:10.1016/j.jaut.2008.09.001 · Cited by 55 · see citing works

TNF Receptor-Associated Factor 5 Limits the Induction of Th2 Immune Responses

So, T., Salek‐Ardakani, S., Nakano, H., Ware, C. F., & Croft, M. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.7.4292 · Cited by 55 · see citing works

Roles of TNF Receptor-Associated Factor 3 in Signaling to B Lymphocytes by Carboxyl-Terminal Activating Regions 1 and 2 of the EBV-Encoded Oncoprotein Latent Membrane Protein 1

Xie, P., & Bishop, G. A. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.173.9.5546 · Cited by 52 · see citing works

Synergistic B Cell Activation by CD40 and the B Cell Antigen Receptor

Haxhinasto, S. A., & Bishop, G. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m310628200 · Cited by 51 · see citing works

Lymphocyte-specific TRAF3 transgenic mice have enhanced humoral responses and develop plasmacytosis, autoimmunity, inflammation, and cancer

Zapata, J. M., Llobet‐Navàs, D., Krajewska, M., Lefebvre, S., Kress, C. L., & Reed, J. C. (2008) · Blood · doi:10.1182/blood-2008-07-165456 · Cited by 48 · see citing works

Differential Regulation of CD40-Mediated TNF Receptor-Associated Factor Degradation in B Lymphocytes

Moore, C. R., & Bishop, G. A. (2005) · The Journal of Immunology · doi:10.4049/jimmunol.175.6.3780 · Cited by 46 · see citing works

Molecular Mechanisms of TNFR-associated Factor 6 (TRAF6) Utilization by the Oncogenic Viral Mimic of CD40, Latent Membrane Protein 1 (LMP1)

Arcipowski, K. M., Stunz, L. L., Graham, J., Kraus, Z., Bush, T. J. V., & Bishop, G. A. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.185983 · Cited by 45 · see citing works

T3JAM, a novel protein that specifically interacts with TRAF3 and promotes the activation of JNK1

Dadgostar, H., Doyle, S. E., Shahangian, A., Garcia, D. E., & Cheng, G. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)01072-x · Cited by 42 · see citing works

Tumor Necrosis Factor (TNF) Signaling, but Not TWEAK (TNF-like Weak Inducer of Apoptosis)-triggered cIAP1 (Cellular Inhibitor of Apoptosis Protein 1) Degradation, Requires cIAP1 RING Dimerization and E2 Binding

Feltham, R., Moulin, M., Vince, J. E., Mace, P. D., Wong, W. W.-L., Anderton, H., Day, C. L., Vaux, D. L., & Silke, J. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.087635 · Cited by 42 · see citing works

Antigen Receptor Signals Rescue B Cells from TLR Tolerance

Poovassery, J. S., Bush, T. J. V., & Bishop, G. A. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0900495 · Cited by 41 · see citing works

A Novel Interaction between Protein Kinase D and TNF Receptor-Associated Factor Molecules Regulates B Cell Receptor-CD40 Synergy

Haxhinasto, S. A., & Bishop, G. A. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.9.4655 · Cited by 39 · see citing works

Multiple Carboxyl-Terminal Regions of the EBV Oncoprotein, Latent Membrane Protein 1, Cooperatively Regulate Signaling to B Lymphocytes Via TNF Receptor-Associated Factor (TRAF)-Dependent and TRAF-Independent Mechanisms

Busch, L. K., & Bishop, G. A. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.167.10.5805 · Cited by 39 · see citing works

Both Amino- and Carboxyl-Terminal Domains of TRAF3 Negatively Regulate NF-κB Activation Induced by OX40 Signaling

Takaori‐Kondo, A., Hori, T., Fukunaga, K., Morita, R., Kawamata, S., & Uchiyama, T. (2000) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2000.2860 · Cited by 38 · see citing works

TRAF5 is a critical mediator of in vitro signals and in vivo functions of LMP1, the viral oncogenic mimic of CD40

Kraus, Z., Nakano, H., & Bishop, G. A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0903786106 · Cited by 38 · see citing works

Dissection of B cell differentiation during primary immune responses in mice with altered CD40 signals

Yasui, T., Muraoka, M., Takaoka-Shichijo, Y., Ishida, I., Takegahara, N., Uchida, J., Kumanogoh, A., Suematsu, S., Suzuki, M., & Kikutani, H. (2002) · International Immunology · doi:10.1093/intimm/14.3.319 · Cited by 38 · see citing works

Multiple roles of TRAF3 signaling in lymphocyte function

Bishop, G. A., & Xie, P. (2007) · Immunologic Research · doi:10.1007/s12026-007-0068-1 · Cited by 37 · see citing works

The Tyrosine Kinase c-Src Enhances RIG-I (Retinoic Acid-inducible Gene I)-elicited Antiviral Signaling

Johnsen, I. B., Nguyen, T. T., Bergstrøm, B., Fitzgerald, K. A., & Anthonsen, M. W. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m808233200 · Cited by 36 · see citing works

TNF Receptor-Associated Factor 5 Is Required for Optimal T Cell Expansion and Survival in Response to Infection

Kraus, Z., Haring, J. S., & Bishop, G. A. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.11.7800 · Cited by 36 · see citing works

Role of Tumor Necrosis Factor (TNF) Receptor-associated Factor 2 (TRAF2) in Distinct and Overlapping CD40 and TNF Receptor 2/CD120b-mediated B Lymphocyte Activation

Munroe, M. E., & Bishop, G. A. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m410539200 · Cited by 35 · see citing works

TNAP, a Novel Repressor of NF-κB-inducing Kinase, Suppresses NF-κB Activation

Hu, W.-H., Mo, X.-M., Walters, W. M., Brambilla, R., & Bethea, J. R. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m405699200 · Cited by 33 · see citing works

Roles of the TRAF2/3 Binding Site in Differential B Cell Signaling by CD40 and Its Viral Oncogenic Mimic, LMP1

Graham, J. P., Moore, C. R., & Bishop, G. A. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0900442 · Cited by 28 · see citing works

CpG oligodeoxynucleotides enhance the capacity of adenovirus-mediated CD154 gene transfer to generate effective B-cell lymphoma vaccines.

Rieger, R., & Kipps, T. J. (2003) · PubMed · Cited by 27 · see citing works

TRAF-3 interacts with p62 nucleoporin, a component of the nuclear pore central plug that binds classical NLS-containing import complexes

Gamper, C. J., van Eyndhoven, W. G., Schweiger, E., Mossbacher, M., Koo, B., & Lederman, S. M. (2000) · Molecular Immunology · doi:10.1016/s0161-5890(00)00015-8 · Cited by 26 · see citing works

A novel polymorphism of the human CD40 receptor with enhanced function

Peters, A. L., Plenge, R. M., Graham, R., Altshuler, D., Moser, K. L., Gaffney, P. M., & Bishop, G. A. (2008) · Blood · doi:10.1182/blood-2008-02-138925 · Cited by 25 · see citing works

Cutting Edge: Importance of IL-6 and Cooperation between Innate and Adaptive Immune Receptors in Cellular Vaccination with B Lymphocytes

Bush, T. J. V., Buchta, C. M., Claudio, J., & Bishop, G. A. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0900968 · Cited by 25 · see citing works

BS69 cooperates with TRAF3 in the regulation of Epstein–Barr virus‐derived LMP1/CTAR1‐induced NF‐κB activation

Ikeda, O., Miyasaka, Y., Yoshida, R., Mizushima, A., Oritani, K., Sekine, Y., Kuroda, M., Yasui, T., Fujimuro, M., Muromoto, R., et al. (2010) · FEBS Letters · doi:10.1016/j.febslet.2010.01.060 · Cited by 17 · see citing works

Differential TRAF3 Utilization by a Variant Human CD40 Receptor with Enhanced Signaling

Peters, A. L., & Bishop, G. A. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1000135 · Cited by 13 · see citing works

TRAF3 Interacts with Smac/DIABLO and Enhances the Proapoptotic Effect of Smac/DIABLO in Cytoplasm

Zhang, C., Xie, L., Cheng, H., & Wang, Y. (2007) · Acta Biochimica et Biophysica Sinica · doi:10.1111/j.1745-7270.2007.00259.x · Cited by 3 · see citing works

The pharmacology of second-generation chimeric antigen receptors

van der Stegen, S. J. C., Hamieh, M., & Sadelain, M. (2015) · Nature Reviews Drug Discovery · doi:10.1038/nrd4597 · Cited by 562 · see citing works

TRAF molecules in cell signaling and in human diseases

Xie, P. (2013) · Journal of Molecular Signaling · doi:10.1186/1750-2187-8-7 · Cited by 468 · see citing works

OX40 signaling favors the induction of TH9 cells and airway inflammation

Xiao, X., Balasubramanian, S., Liu, W., Chu, X., Wang, H., Taparowsky, E. J., Fu, Y., Choi, Y., Walsh, M. C., & Li, X. C. (2012) · Nature Immunology · doi:10.1038/ni.2390 · Cited by 233 · see citing works

ELM—the Eukaryotic Linear Motif resource—2024 update

Kumar, M., Michael, S., Alvarado-Valverde, J., Zeke, A., Lázár, T., Glavina, J., Nagy‐Kanta, E., Donagh, J. M., Kálmán, Z. E., Pascarelli, S., et al. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad1058 · Cited by 185 · see citing works

Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors

Lu, Y., Wang, Q., Xue, G., Bi, E., Ma, X., Wang, A., Qian, J., Dong, C., & Yi, Q. (2018) · Cancer Cell · doi:10.1016/j.ccell.2018.05.004 · Cited by 167 · see citing works

Fine-tuning of dendritic cell biology by the TNF superfamily

deLuca, L. S., & Gommerman, J. L. (2012) · Nature reviews. Immunology · doi:10.1038/nri3193 · Cited by 154 · see citing works

Potential mechanisms and applications of statins on osteogenesis: Current modalities, conflicts and future directions

Oryan, A., Kamali, A., & Moshiri, A. (2015) · Journal of Controlled Release · doi:10.1016/j.jconrel.2015.07.022 · Cited by 152 · see citing works

A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation

Chen, B. B., Coon, T. A., Glasser, J. R., McVerry, B. J., Zhao, J., Zhao, Y., Zou, C., Ellis, B. M., Sciurba, F. C., Zhang, Y., et al. (2013) · Nature Immunology · doi:10.1038/ni.2565 · Cited by 146 · see citing works

Intracellular Signaling Pathways in Rheumatoid Arthritis

Malemud, C. J. (2013) · Journal of Clinical & Cellular Immunology · doi:10.4172/2155-9899.1000160 · Cited by 134 · see citing works

TRAF Molecules in Inflammation and Inflammatory Diseases

Lalani, A., Zhu, S., Gokhale, S., Jin, J., & Xie, P. (2017) · Current Pharmacology Reports · doi:10.1007/s40495-017-0117-y · Cited by 115 · see citing works

Twin DNA Methylation Profiling Reveals Flare‐Dependent Interferon Signature and B Cell Promoter Hypermethylation in Systemic Lupus Erythematosus

Ulff-Møller, C. J., Asmar, F., Liu, Y., Svendsen, A. J., Busato, F., Grønbæk, K., Tost, J., & Jacobsen, S. (2018) · Arthritis & Rheumatology · doi:10.1002/art.40422 · Cited by 94 · see citing works

TRAF3 regulates the effector function of regulatory T cells and humoral immune responses

Chang, J., Hu, H., Jin, J., Puebla‐Osorio, N., Xiao, Y., Gilbert, B. E., Brink, R. A., Ullrich, S. E., & Sun, S. (2013) · The Journal of Experimental Medicine · doi:10.1084/jem.20131019 · Cited by 74 · see citing works

TRAF3 as a Multifaceted Regulator of B Lymphocyte Survival and Activation

Bishop, G. A., Stunz, L. L., & Hostager, B. S. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.02161 · Cited by 69 · see citing works

TRAF3 mediates neuronal apoptosis in early brain injury following subarachnoid hemorrhage via targeting TAK1-dependent MAPKs and NF-κB pathways

Zhou, Y., Tao, T., Liu, G., Gao, X., Gao, Y., Zhuang, Z., Lu, Y., Wang, H., Li, W., Wu, L., et al. (2021) · Cell Death and Disease · doi:10.1038/s41419-020-03278-z · Cited by 68 · see citing works

Genome-Wide Association Study Identifies Novel Susceptibility Genes Associated with Coronary Artery Aneurysm Formation in Kawasaki Disease

Kuo, H., Li, S., Guo, M. M., Huang, Y., Yu, H., Huang, F., Jiao, F., Kuo, H., Andrade, J., & Chan, W. (2016) · PLoS ONE · doi:10.1371/journal.pone.0154943 · Cited by 65 · see citing works

Deciphering the molecular adaptation of the king scallop (Pecten maximus) to heat stress using transcriptomics and proteomics

Artigaud, S., Richard, J., Thorne, M. A. S., Lavaud, R., Flye‐Sainte‐Marie, J., Jean, F., Peck, L. S., Clark, M. S., & Pichereau, V. (2015) · BMC Genomics · doi:10.1186/s12864-015-2132-x · Cited by 64 · see citing works

The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2

Yi, Z., Lin, W., Stunz, L. L., & Bishop, G. A. (2014) · Nature Immunology · doi:10.1038/ni.2944 · Cited by 61 · see citing works

HSCARG Negatively Regulates the Cellular Antiviral RIG-I Like Receptor Signaling Pathway by Inhibiting TRAF3 Ubiquitination via Recruiting OTUB1

Peng, Y., Xu, R., & Zheng, X. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1004041 · Cited by 57 · see citing works

TRAF3 deficiency promotes metabolic reprogramming in B cells

Mambetsariev, N., Lin, W., Wallis, A. M., Stunz, L. L., & Bishop, G. A. (2016) · Scientific Reports · doi:10.1038/srep35349 · Cited by 57 · see citing works

Roles of TRAFs in NF-κB signaling pathways mediated by BAFF

Tang, X., Zhang, L., & Wei, W. (2018) · Immunology Letters · doi:10.1016/j.imlet.2018.01.010 · Cited by 56 · see citing works

De Novo Characterization of Japanese Scallop Mizuhopecten yessoensis Transcriptome and Analysis of Its Gene Expression following Cadmium Exposure

Meng, X., Liu, M., Jiang, K., Wang, B., Tian, X., Sun, S., Luo, Z., Qiu, C.-W., & Wang, L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0064485 · Cited by 53 · see citing works

HIV-1 Tat C-mediated regulation of tumor necrosis factor receptor-associated factor-3 by microRNA 32 in human microglia

Mishra, R., Chhatbar, C., & Singh, S. K. (2012) · Journal of Neuroinflammation · doi:10.1186/1742-2094-9-131 · Cited by 52 · see citing works

Nuclear TRAF3 is a negative regulator of CREB in B cells

Mambetsariev, N., Lin, W., Stunz, L. L., Hanson, B. M., Hildebrand, J. M., & Bishop, G. A. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1514586113 · Cited by 51 · see citing works

The adaptor TRAF5 limits the differentiation of inflammatory CD4+ T cells by antagonizing signaling via the receptor for IL-6

Nagashima, H., Okuyama, Y., Asao, A., Kawabe, T., Yamaki, S., Nakano, H., Croft, M., Ishii, N., & So, T. (2014) · Nature Immunology · doi:10.1038/ni.2863 · Cited by 50 · see citing works

Tumor necrosis factor receptor-associated factor 5 (Traf5) acts as an essential negative regulator of hepatic steatosis

Gao, L., Wang, P., Zhang, Y., Yu, C., Ji, Y., Wang, X., Zhang, P., Jiang, X., Jin, H., Huang, Z., et al. (2016) · Journal of Hepatology · doi:10.1016/j.jhep.2016.03.006 · Cited by 49 · see citing works

Reprogramming of Murine Macrophages through TLR2 Confers Viral Resistance via TRAF3-Mediated, Enhanced Interferon Production

Perkins, D. J., Polumuri, S. K., Pennini, M. E., Lai, W., Xie, P., & Vogel, S. N. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003479 · Cited by 47 · see citing works

Roles for TNF-receptor associated factor 3 (TRAF3) in lymphocyte functions

Yi, Z., Lin, W., Stunz, L. L., & Bishop, G. A. (2013) · Cytokine & Growth Factor Reviews · doi:10.1016/j.cytogfr.2013.12.002 · Cited by 46 · see citing works

Neuron-Specific Tumor Necrosis Factor Receptor–Associated Factor 3 Is a Central Regulator of Neuronal Death in Acute Ischemic Stroke

Gong, J., Li, Z.-Z., Guo, S., Zhang, X., Zhang, P., Zhao, G., Gao, L., Zhang, Y., Zheng, A., Zhang, X.-F., et al. (2015) · Hypertension · doi:10.1161/hypertensionaha.115.05430 · Cited by 45 · see citing works

Targeted deep sequencing of gastric marginal zone lymphoma identified alterations of TRAF3 and TNFAIP3 that were mutually exclusive for MALT1 rearrangement

Hyeon, J., Lee, B., Shin, S., Yoo, H. Y., Kim, S. J., Kim, W. S., Park, W., & Ko, Y. H. (2018) · Modern Pathology · doi:10.1038/s41379-018-0064-0 · Cited by 43 · see citing works

Cordyceps polysaccharide marker CCP modulates immune responses via highly selective TLR4/MyD88/p38 axis

Zhang, Q., Liu, M., Li, L., Chen, M., Puno, P. T., Bao, W.-R., Zheng, H., Wen, X., Cheng, H., Fung, H.-Y., et al. (2021) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2021.118443 · Cited by 41 · see citing works

TRAF 3, ubiquitination, and B‐lymphocyte regulation

Lin, W., Hostager, B. S., & Bishop, G. A. (2015) · Immunological Reviews · doi:10.1111/imr.12299 · Cited by 40 · see citing works

Early onset senescence and cognitive impairment in a murine model of repeated mTBI

Schwab, N., Ju, Y., & Hazrati, L.-N. (2021) · Acta Neuropathologica Communications · doi:10.1186/s40478-021-01190-x · Cited by 39 · see citing works

Genome-wide identification and characterization of TRAF genes in the Yesso scallop (Patinopecten yessoensis) and their distinct expression patterns in response to bacterial challenge

Wang, J., Wang, R., Wang, S., Zhang, M., Ma, X., Liu, P., Zhang, M., Hu, X., Zhang, L., Wang, S., et al. (2015) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2015.09.050 · Cited by 37 · see citing works

The kinase CK1ɛ controls the antiviral immune response by phosphorylating the signaling adaptor TRAF3

Zhou, Y., He, C., Yan, D., Liu, F., Liu, H., Chen, J., Cao, T., Zuo, M., Wang, P., Ge, Y., et al. (2016) · Nature Immunology · doi:10.1038/ni.3395 · Cited by 37 · see citing works

Characterization of the black carp TRAF6 signaling molecule in innate immune defense

Jiang, S., Xiao, J., Li, J., Chen, H., Wang, C., Feng, C., & Feng, H. (2017) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2017.06.011 · Cited by 35 · see citing works

The TNF receptor super family in immune regulation

Ware, C. F. (2011) · Immunological Reviews · doi:10.1111/j.1600-065x.2011.01065.x · Cited by 34 · see citing works

A Complex Relationship between TRAF3 and Non-Canonical NF-κB2 Activation in B Lymphocytes

Lin, W., Hildebrand, J. M., & Bishop, G. A. (2013) · Frontiers in Immunology · doi:10.3389/fimmu.2013.00477 · Cited by 34 · see citing works

The Role of Tumor Necrosis Factor Associated Factors (TRAFs) in Vascular Inflammation and Atherosclerosis

Gissler, M. C., Stachon, P., Wolf, D., & Marchini, T. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.826630 · Cited by 34 · see citing works

Integrated Biomarker Responses in European Seabass Dicentrarchus Labrax (Linnaeus, 1758) Chronically Exposed to Pvc Microplastics

Pedà, C., Romeo, T., Panti, C., Caliani, I., Casini, S., Marsili, L., Campani, T., Baini, M., Limonta, G., de Rysky, E., et al. (2022) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2022.129488 · Cited by 34 · see citing works

TRAF3 enhances TCR signaling by regulating the inhibitors Csk and PTPN22

Wallis, A. M., Wallace, E. C., Hostager, B. S., Yi, Z., Houtman, J. C. D., & Bishop, G. A. (2017) · Scientific Reports · doi:10.1038/s41598-017-02280-4 · Cited by 33 · see citing works

TRAF4 enhances oral squamous cell carcinoma cell growth, invasion and migration by Wnt-β-catenin signaling pathway.

Yang, J., Wei, D., Wang, W., Shen, B., Xu, S., & Cao, Y. (2015) · PubMed Central · Cited by 32 · see citing works

Microarray expression profile of circular RNAs and mRNAs in children with systemic lupus erythematosus

Li, S., Zhang, J., Tan, X., Deng, J., Li, Y., Piao, Y., Li, C., Yang, W., Mo, W., Sun, F., et al. (2019) · Clinical Rheumatology · doi:10.1007/s10067-018-4392-8 · Cited by 32 · see citing works

TRAF3 as a powerful and multitalented regulator of lymphocyte functions

Bishop, G. A. (2016) · Journal of Leukocyte Biology · doi:10.1189/jlb.2mr0216-063r · Cited by 32 · see citing works

Insights into potential pathogenesis mechanisms associated with Campylobacter jejuni-induced abortion in ewes

Sanad, Y. M., Jung, K., Kashoma, I. P., Zhang, X., Kassem, I. I., Saif, Y. Μ., & Rajashekara, G. (2014) · BMC Veterinary Research · doi:10.1186/s12917-014-0274-8 · Cited by 31 · see citing works

Transforming growth factor β activated kinase 1: a potential therapeutic target for rheumatic diseases

Fechtner, S., Fox, D. A., & Ahmed, S. (2016) · Rheumatology · doi:10.1093/rheumatology/kew301 · Cited by 31 · see citing works

TNF receptor associated factor 3 plays a key role in development and function of invariant natural killer T cells

Yi, Z., Stunz, L. L., & Bishop, G. A. (2013) · The Journal of Experimental Medicine · doi:10.1084/jem.20122135 · Cited by 31 · see citing works

Roles of TRAF3 in T cells: many surprises

Yi, Z., Wallis, A. M., & Bishop, G. A. (2015) · Cell Cycle · doi:10.1080/15384101.2015.1021524 · Cited by 29 · see citing works

TRAF3 Is Required for NF-κB Pathway Activation Mediated by HTLV Tax Proteins

Fochi, S., Bergamo, E., Serena, M., Mutascio, S., Journo, C., Mahieux, R., Ciminale, V., Bertazzoni, U., Zipeto, D., & Romanelli, M. G. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01302 · Cited by 29 · see citing works

Betting on improved cancer immunotherapy by doubling down on CD134 and CD137 co-stimulation

Adler, A. J., & Vella, A. T. (2012) · OncoImmunology · doi:10.4161/onci.22837 · Cited by 27 · see citing works

Transcriptome analysis of host anti-Aeromonas hydrophila infection revealed the pathogenicity of A. hydrophila to American eels (Anguilla rostrata)

Guo, S., Wan, Q., Xu, M. J., Chen, M., & Chen, Z. (2024) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2024.109504 · Cited by 25 · see citing works

Functional characterization of tumor necrosis factor receptor-associated factor 3 of sea perch (Lateolabrax japonicas) in innate immune

Zhang, W., Jia, P., Liu, W., Li, Y., Yi, M., & Jia, K. (2018) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2018.01.039 · Cited by 25 · see citing works

Up-regulation and Pre-activation of TRAF3 and TRAF5 in Inflammatory Bowel Disease

Shen, J., Qiao, Y., Ran, Z., & Wang, T. (2013) · International Journal of Medical Sciences · doi:10.7150/ijms.5457 · Cited by 25 · see citing works

The oncogenic membrane protein LMP1 sequesters TRAF3 in B-cell lymphoma cells to produce functional TRAF3 deficiency

Bangalore-Prakash, P., Stunz, L. L., Mambetsariev, N., Whillock, A. L., Hostager, B. S., & Bishop, G. A. (2017) · Blood Advances · doi:10.1182/bloodadvances.2017009670 · Cited by 21 · see citing works

USP25 promotes endotoxin tolerance via suppressing K48-linked ubiquitination and degradation of TRAF3 in Kupffer cells

Wen, J., He, B., Chen, N., Zhang, W., Zhu, X., Li, P., & Gong, J. (2018) · Molecular Immunology · doi:10.1016/j.molimm.2018.12.017 · Cited by 21 · see citing works

TRAF5 protects against myocardial ischemia reperfusion injury via AKT signaling

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Dysregulated TRAF3 and BCL2 Expression Promotes Multiple Classes of Mature Non-hodgkin B Cell Lymphoma in Mice

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RIP2 promotes glioma cell growth by regulating TRAF3 and activating the NF‑κB and p38 signaling pathways

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TRAF3 Regulates Homeostasis of CD8+ Central Memory T Cells

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Regulatory T Cells in B Cell Follicles

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Recognition of TRAIP with TRAFs: Current understanding and associated diseases

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Endotoxin Tolerance Inhibits Degradation of Tumor Necrosis Factor Receptor–Associated Factor 3 by Suppressing Pellino 1 Expression and the K48 Ubiquitin Ligase Activity of Cellular Inhibitor of Apoptosis Protein 2

Li, P., Liu, H., Zhang, Y., Liao, R., He, K., Ruan, X. Z., & Gong, J. (2016) · The Journal of Infectious Diseases · doi:10.1093/infdis/jiw279 · Cited by 16 · see citing works

Prognostic Significance of Autophagy-Relevant Gene Markers in Colorectal Cancer

He, Q., Li, Z., Yin, J., Li, Y., Yin, Y., Lei, X., & Zhu, W. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.566539 · Cited by 16 · see citing works

Molecular characteristics and function study of TNF receptor-associated factor 5 from grouper (Epinephelus coioides)

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Disruption of Tumor Necrosis Factor Receptor-Associated Factor 5 Exacerbates Murine Experimental Colitis via Regulating T Helper Cell-Mediated Inflammation

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TRAF3 regulation of inhibitory signaling pathways in B and T lymphocytes by kinase and phosphatase localization

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Prominent Targets for Cancer Care: Immunotherapy Perspective

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RNA-seq analysis revealed the pathogenicity of Vibrio vulnificus to American eel (Anguilla rostrata) and the strategy of host anti-V. vulnificus infection

Xu, M. J., Wang, Y., Wan, Q., Chen, M., & Guo, S. (2023) · Microbial Pathogenesis · doi:10.1016/j.micpath.2023.106498 · Cited by 13 · see citing works

The SMAC mimetic birinapant attenuates lipopolysaccharide-induced liver injury by inhibiting the tumor necrosis factor receptor–associated factor 3 degradation in Kupffer cells

Liu, H., Liao, R., He, K., Zhu, X., Li, P., & Gong, J. (2017) · Immunology Letters · doi:10.1016/j.imlet.2017.02.016 · Cited by 12 · see citing works

MicroRNA-628-5p Facilitates Enterovirus 71 Infection by Suppressing TRAF3 Signaling

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Transcriptome Analysis of Host Anti-Vibrio harveyi Infection Revealed the Pathogenicity of V. harveyi to American Eel (Anguilla rostrata)

Chen, M., Wan, Q., Xu, M. J., Chen, Z., & Guo, S. (2024) · Marine Biotechnology · doi:10.1007/s10126-024-10298-9 · Cited by 11 · see citing works

TRAF3 of blunt snout bream participates in host innate immune response to pathogenic bacteria via NF-κB signaling pathway

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Genome-wide identification of TNF receptor-associated factors in Japanese flounder (Paralichthys olivaceus) and functional analysis of resistance to temperature and Edwardsiella tarda stress

Wang, R., Han, P., Liu, X., & Wang, X. (2023) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2023.108862 · Cited by 11 · see citing works

TRAF3 in T Cells Restrains Negative Regulators of LAT to Promote TCR/CD28 Signaling

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Molecular analysis of apoptosis pathway after photodynamic therapy in breast cancer: Animal model study

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Identification and characterization of receptor-interacting protein 2 as a TNFR-associated factor 3 binding partner

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NLRP12 Senses the SARS-CoV-2 Membrane Protein and Promotes an Inflammatory Response

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Meta-transcriptomic comparison of two sponge holobionts feeding on coral- and macroalgal-dissolved organic matter

Campana, S., Riesgo, A., Jongepier, E., Fuß, J., Gerard Muyzer, C., & de Goeij, J. M. (2022) · BMC Genomics · doi:10.1186/s12864-022-08893-y · Cited by 9 · see citing works

Molecular insights into the immune response of Ruditapes philippinarum under Vibrio anguillarum infection at high temperature

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De novo characterization of venom apparatus transcriptome of Pardosa pseudoannulata and analysis of its gene expression in response to Bt protein

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TRAF5 splicing variants associate with TRAF3 and RIP1 in NF-κB and type I IFN signaling in large yellow croaker Larimichthys crocea

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Nanomaterials in Wound Healing: Mechanisms, Applications, and Future Prospects

Rani, K., Singh, G., Narwal, S., Chopra, B., & Dhingra, A. K. (2024) · Current Nanomedicine · doi:10.2174/0124681873294822240517073406 · Cited by 7 · see citing works

Translational utility of experimental autoimmune encephalomyelitis: recent developments

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Expression and functional analysis of tumor necrosis factor receptor (TNFR)-associated factor 5 from Nile tilapia, Oreochromis niloticus

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Bioinformatics Analysis of miRNAs Targeting TRAF5 in DLBCL Involving in NF-κB Signaling Pathway and Affecting the Apoptosis and Signal Transduction

Li, C., Huang, L., Wen, Y., Yi, M., & Gao, M. (2022) · Genetics Research · doi:10.1155/2022/3222253 · Cited by 5 · see citing works

Computational trans-omics approach characterised methylomic and transcriptomic involvements and identified novel therapeutic targets for chemoresistance in gastrointestinal cancer stem cells

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Antibodies and longevity of dairy cattle : genetic analysis

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Prediction of human protein interactome of dengue virus non-structural protein 5 (NS5) and its downstream immunological implications

Bhatnagar, P., Bajpai, P., Shrinet, J., Murali‐Krishna, K., Chandele, A., & Sitaraman, R. (2023) · 3 Biotech · doi:10.1007/s13205-023-03569-0 · Cited by 4 · see citing works

NS5 hijacks TRAF3 to inhibit type I interferon signaling during duck Tembusu virus infection

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Ablation of myd88 alters the immune gene expression and immune cell recruitment during VHSV infection in zebrafish

Madushani, K. P., Shanaka, K. A. S. N., Jung, S., Kim, M., & Lee, J. (2023) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2023.109006 · Cited by 4 · see citing works

METTL3 ‐mediated m 6 A methylation of TRAF5 inhibits lung adenocarcinoma cell metastasis via activation of the PI3K / AKT / NF‐κB signaling pathway

Zhou, Y., Li, J., Zheng, Q., Ren, K., & Yi, C. (2023) · The Kaohsiung Journal of Medical Sciences · doi:10.1002/kjm2.12791 · Cited by 3 · see citing works

TRAF5 Deficiency Ameliorates the Severity of Dextran Sulfate Sodium Colitis by Decreasing TRAF2 Expression in Nonhematopoietic Cells

Phung, H. T., Nagashima, H., Kobayashi, S., Asano, N., Machiyama, T., Sakurai, T., Tayama, S., Asao, A., Imatani, A., Kawabe, T., et al. (2020) · ImmunoHorizons · doi:10.4049/immunohorizons.2000007 · Cited by 3 · see citing works

Clinical applications and challenges of CD40/CD40L signaling regulation in autoimmune diseases

Man, Y., Chen, X., Liu, Y., Zhang, B., Hu, J., & Hou, X. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1830312 · Cited by 2 · see citing works

Roles of mdh and MAP1981c in Mycobacterium avium subsp. paratuberculosis intracellular survival within bovine monocyte-derived macrophages via CRISPR interference

Lee, J. H., Lee, E., Xiang, X., Kyung, S. M., Seo, J., Lee, W., Park, H.-E., Shin, M.-K., & Yoo, H. S. (2026) · Microbial Pathogenesis · doi:10.1016/j.micpath.2026.108724 · Cited by 2 · see citing works

Machine Learning for Building Immune Genetic Model in Hepatocellular Carcinoma Patients

Liu, J., Chen, Z., & Li, W. (2021) · Journal of Oncology · doi:10.1155/2021/6676537 · Cited by 2 · see citing works

Tumor necrosis factor receptor-associated factor 5 protects against intimal hyperplasia by regulation of macrophage polarization via directly targeting PPARγ

Cheng, W., Chao, S.-P., Zhao, F., Cai, H., Zeng, Z., Cao, J., Jin, Z., Deng, K., Hu, X., Wang, H., et al. (2024) · Inflammation Research · doi:10.1007/s00011-024-01875-8 · Cited by 1 · see citing works

Molecular characterization and expression analysis of the TRAF gene family in the fourfinger threadfin (Eleutheronema tetradactylum)

Wang, L., Pan, Y., Zhang, H., Jin, M., Zheng, A., Liu, W., Liu, W., Zhang, J., Tang, B., Huang, J., et al. (2025) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2025.110906 · Cited by 1 · see citing works

Defective IgG Class Switching in the Spleen of TRAF5-Deficient Mice Reveals a Role for TRAF5 in CD40-Mediated B Cell Responses During Obesity-Associated Inflammation

Wakaizumi, T., Hikosaka‐Kuniishi, M., Ozawa, Y., Sato, A., Iwata, C., Wada, T., Sasaoka, T., Morita, M., & So, T. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26199494 · Cited by 1 · see citing works

RNA-seq transcriptome analysis provides new insights into the negative effects of tannic acid on the intestinal function of Brandt’s voles (Lasiopodomys brandtii)

Gu, M., Han, Y., Dai, X., Ma, X., Ge, W., Wei, W., & Yang, S. (2023) · Gene · doi:10.1016/j.gene.2023.147944 · Cited by 1 · see citing works

FRI0352 Ubiquitin E3 Ligase F Box Component, Fbxo3 Modulates Pro-Inflammatory Gene Expressions in Rheumatoid Arthritis via Regulation of Nuclear Factor-Kappab

Yong-Jin, K., Lee, S., Jung-Sik, S., Park, Y.-B., Lee, S., & Park, M. (2014) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2014-eular.5985 · Cited by 1 · see citing works

FRI0351 The Feedback Loop between Long Noncoding RNA NRON and NFAT5 Regulates the Inflammatory Response of Rheumatoid Arthritis Synovial Fibroblasts

Umekita, K., Trenkmann, M., Kolling, C., Michel, B. A., Gay, R., Gay, S., & Frank‐Bertoncelj, M. (2014) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2014-eular.3213 · Cited by 1 · see citing works

The Roles of TRAF3 in Immune Responses

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Roles of TRAF3 in T cells: many surprises

Yi, Z., Wallis, A. M., & Bishop, G. A. (2015) · Cell Cycle · doi:10.1080/15384101.2015.1021524 · Cited by 29 · see citing works

Multiple roles of TRAF3 signaling in lymphocyte function

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Role of tumor necrosis factor receptor-associated factor 5 in B- and T-lymphocytes

Hikosaka‐Kuniishi, M., Ishii, N., & So, T. (2023) · Exploration of Immunology · doi:10.37349/ei.2023.00088 · Cited by 5 · see citing works

TRAF 3, ubiquitination, and B‐lymphocyte regulation

Lin, W., Hostager, B. S., & Bishop, G. A. (2015) · Immunological Reviews · doi:10.1111/imr.12299 · Cited by 40 · see citing works