The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Relative safety of 4 weeks of blood flow‐restricted resistance exercise in young, healthy adults
Open accessAbstract
This study evaluated the effect of 4 weeks of low‐load resistance exercise with blood flow restriction (BFRE) on increasing strength in comparison with high‐load resistance exercise (HLE), and assessed changes in blood, vascular and neural function. Healthy adults performed leg extension BFRE or HLE 3 days/week at 30% and 80% of strength, respectively. During BFRE, a cuff on the upper leg was inflated to 30% above systolic blood pressure. Strength, pulse‐wave velocity (PWV), ankle‐brachial index (ABI), prothrombin time (PT) and nerve conduction (NC) were measured before and after training. Markers of coagulation (fibrinogen and D‐dimer), fibrinolysis [tissue plasminogen activator (tPA)] and inflammation [high sensitivity C‐reactive protein (hsCRP)] were measured in response to the first and last exercise bouts. Strength increased 8% with BFRE and 13% with HLE (P<0.01). No changes in PWV, ABI, PT or NC were observed following training for either group (P>0.05). tPA antigen increased 30–40% immediately following acute bouts of BFRE and HLE (P=0.01). No changes were observed in fibrinogen, D‐dimer or hsCRP (P>0.05). These findings indicate that both protocols increase the strength without altering nerve or vascular function, and that a single bout of both protocols increases fibrinolytic activity without altering selected markers of coagulation or inflammation in healthy individuals.
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Cites
Progression Models in Resistance Training for Healthy Adults
(2002) · Medicine and Science in Sports and Exercise · doi:10.1097/00005768-200202000-00027 · Cited by 2,979
Aortic pulse wave velocity as a marker of cardiovascular risk in hypertensive patients
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Hakkinen, K., Newton, R. U., Gordon, S. E., McCormick, M., Volek, J. S., Nindl, B. C., Gotshalk, L. A., Campbell, W. W., Evans, W. J., Hakkinen, A., et al. (1998) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/53a.6.b415 · Cited by 423
Reliability of techniques to assess human neuromuscular function in vivo
Clark, B. C., Cook, S. B., & Ploutz-Snyder, L. L. (2007) · Journal of Electromyography and Kinesiology · doi:10.1016/j.jelekin.2005.11.008 · Cited by 107 · cited 1×
“We utilized techniques described previously by our group (Clark et al., 2007), which involves stimulating the tibial nerve (Grass S88, Quincy, Massachusetts, USA) and recording the soleus electromyogram signal with surface electrodes at a sampling rate of 100 kHz (MP150, BioPac Systems).”
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Cited by
Blood Flow Restriction Exercise: Considerations of Methodology, Application, and Safety
Patterson, S. D., Hughes, L., Warmington, S., Burr, J., Scott, B. R., Owens, J., Abe, T., Nielsen, J. L., Libardi, C. A., Laurentino, G., et al. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00533 · Cited by 917
Lixandrão, M. E., Ugrinowitsch, C., Berton, R., Vechin, F. C., Conceição, M. S., Damas, F., Libardi, C. A., & Roschel, H. (2018) · Sports Medicine · doi:10.1007/s40279-017-0795-y · Cited by 554
Potential safety issues with blood flow restriction training
Loenneke, J. P., Wilson, J. M., Wilson, G. J., Pujol, T. J., & Bemben, M. G. (2011) · Scandinavian Journal of Medicine & Science in Sports · doi:10.1111/j.1600-0838.2010.01290.x · Cited by 275
Blood Flow Restricted Exercise and Vascular Function
Horiuchi, M., & Okita, K. (2012) · International Journal of Vascular Medicine · doi:10.1155/2012/543218 · Cited by 75
AMPOMAH, K., AMANO, S., WAGES, N. P., VOLZ, L., CLIFT, R., LUDIN, A. F. M., NAKAZAWA, M., LAW, T. D., MANINI, T. M., THOMAS, J. S., et al. (2019) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000001984 · Cited by 18
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Metadata
- Authors
- Clark, B. C., Manini, T. M., Hoffman, R. L., Williams, P. S., Guiler, M. K., Knutson, M. J., McGLynn, M. L., & Kushnick, M. R.
- Venue
- Scandinavian Journal of Medicine & Science in Sports
- Publisher
- Wiley
- Published
- 2011-09-14
- Volume
- 21
- Issue
- 5
- Pages
- 653-662
- ISSN
- 0905-7188 (ISSN-L)
- 1600-0838
- OpenAlex
- W1540697034
- Cited by
- 233
- References
- 5
- FWCI
- 25.96
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Clark, B. C., Manini, T. M., Hoffman, R. L., Williams, P. S., Guiler, M. K., Knutson, M. J., McGLynn, M. L., & Kushnick, M. R. (2011). Relative safety of 4 weeks of blood flow‐restricted resistance exercise in young, healthy adults. Scandinavian Journal of Medicine & Science in Sports. https://doi.org/10.1111/j.1600-0838.2010.01100.x
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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