The DOI matches its Crossref record.
Four-year Follow-up of a Prospective Trial of HLA and MICA Antibodies on Kidney Graft Survival
Open accessAbstract
In 2002, 1329 patients with functioning transplants were prospectively tested for HLA antibodies in the 13th International Histocompatibility Workshop. Four years after testing, deceased donor graft survival among 806 patients not having antibodies in 2002 was 81% compared to 58% for 158 patients with HLA antibodies (p < 0.0001) and 72% for 69 patients with MICA antibodies (p = 0.02). Hazard ratio (HR) using death-censored graft survival from multivariate analysis of HLA antibodies was 3.3 (p < 0.00001) and 2.04 for MICA (p = 0.01). In the 14th Workshop, at 1 year follow-up, survival for 1319 patients receiving deceased donor grafts and no HLA antibodies was 96% compared to 94% for 344 patients with HLA antibodies (p = 0.0004) and 83% survival for 33 patients with MICA (p = 0.0005). HR from multivariate analysis: HLA antibodies was 3.6 (p < 0.00001) and 6.1 for MICA (p = 0.006). Twelve patients with donor specific antibodies tested by single antigen beads had a 1 year survival of 64% (p = 0.008), and 27 patients with non-donor specific 'strong' antibodies had a 66% survival (p = 0.0003) compared to 92% survival in those with no antibodies. In conclusion, these two prospective trials, after 1 and 4 years, provided strong evidence that HLA and MICA antibodies are associated with graft failure.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Sellarés, J., de Freitas, D. G., Mengel, M., Reeve, J., Einecke, G., Sis, B., Hidalgo, L. G., Famulski, K., Matas, A., & Halloran, P. F. (2012) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2011.03840.x · Cited by 1,590
Tait, B. D., Süsal, C., Gebel, H. M., Nickerson, P. W., Zachary, A. A., Claas, F. H. J., Reed, E. F., Bray, R. A., Campbell, P., Chapman, J. R., et al. (2013) · Transplantation · doi:10.1097/tp.0b013e31827a19cc · Cited by 787
Long-term follow-up of the West of Scotland Coronary Prevention Study
Ford, I., Murray, H., Packard, C. J., Shepherd, J., Macfarlane, P. W., & Cobbe, S. M. (2007) · New England Journal of Medicine · doi:10.1056/nejmoa065994 · Cited by 416
Lachmann, N., Terasaki, P. I., Budde, K., Liefeldt, L., Kahl, A., Reinke, P., Pratschke, J., Rudolph, B., Schmidt, D., Salama, A., et al. (2009) · Transplantation · doi:10.1097/tp.0b013e3181a44206 · Cited by 344
Self-citationHigh Risk of Sensitization After Failed Islet Transplantation
Campbell, P. M., Senior, P. A., Salam, A., LaBranche, K., Bigam, D. L., Kneteman, N. M., Imes, S., Halpin, A., Ryan, E. A., & Shapiro, A. M. J. (2007) · American Journal of Transplantation · doi:10.1111/j.1600-6143.2007.01923.x · Cited by 173
Metadata
- Authors
- Terasaki, P., Ozawa, M., & Castro, R.
- Venue
- American Journal of Transplantation
- Publisher
- Elsevier BV
- Published
- 2007-02
- Volume
- 7
- Issue
- 2
- Pages
- 408-415
- ISSN
- 1600-6135 (ISSN-L)
- OpenAlex
- W1994085514
- Cited by
- 362
- References
- 0
- FWCI
- 18.27
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Four-year Follow-up of a Prospective Trial of HLA and MICA Antibodies on Kidney Graft Survival. https://app.cochat.ai/papers/10.1111/j.1600-6143.2006.01644.x
- The paper
- Terasaki, P., Ozawa, M., & Castro, R. (2007). Four-year Follow-up of a Prospective Trial of HLA and MICA Antibodies on Kidney Graft Survival. American Journal of Transplantation. https://doi.org/10.1111/j.1600-6143.2006.01644.x
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
