The link between periodontal disease and cardiovascular disease is probably inflammation

Davé, S; Van Dyke, TE

doi:10.1111/j.1601-0825.2007.01438.x

Cited by 88Oral microbiology and periodontitis researchInfective Endocarditis Diagnosis and ManagementDental Research and COVID-19

The link between periodontal disease and cardiovascular disease is probably inflammation

Davé, S, Van Dyke, TE·2008·Oral Diseases

DOI 10.1111/j.1601-0825.2007.01438.x

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Abstract

A periodontal–cardiovascular relationship has been postulated for several years but a definitive etiologic relationship has not been established. However, evidence continues to accumulate epidemiologic and otherwise that periodontitis at the very least plays a contributory role in the progression of cardiovascular disease. This paper will argue if indeed such a causative relationship exists, it is most likely based on the incremental contribution of chronic periodontal inflammation on systemic inflammation rather than the direct colonization of atherosclerotic plaques with periodontal pathogens.

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“Notably, oral bacteria are also associated with many systemic diseases including arthritis28, cardiovascular disease3 and diabetes4, in addition to diseases of the oral cavity1,2.”
From Sequencing ancient calcified dental plaque shows changes in oral microbiota with dietary shifts of the Neolithic and Industrial revolutions (2013) · cites this paper as [3]
Commensal microbiota comprise the majority of cells in the body and play a key role in human health.
“Commensal microbiota comprise the majority of cells in the body and play a key role in human health1-5,10.”
From Sequencing ancient calcified dental plaque shows changes in oral microbiota with dietary shifts of the Neolithic and Industrial revolutions (2013) · cites this paper as [3]

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Authors: Davé, S., & Van Dyke, T.
Venue: Oral Diseases
Publisher: Wiley
Published: 2008-02-22
Volume: 14
Issue: 2
Pages: 95-101
ISSN: 1354-523X (ISSN-L)
1601-0825
DOI: 10.1111/j.1601-0825.2007.01438.x
OpenAlex: W2026688907
Cited by: 88
References: 41
Citations by year: 2024: 1 · 2023: 3 · 2022: 1 · 2021: 3 · 2020: 5 · 2019: 7 · 2018: 4 · 2017: 5 · 2016: 4 · 2015: 12 · 2014: 5 · 2013: 9 · 2012: 7
FWCI: 1.05
Type: journal article
Language: en
Open access: closed
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: Oral Diseases (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
Health Sciences › Medicine › Epidemiology › Infective Endocarditis Diagnosis and Management
Health Sciences › Dentistry › General Dentistry › Dental Research and COVID-19
Keywords: periodontitis, cardiovascular disease, systemic inflammation, atherosclerosis, periodontal pathogens
MeSH terms: Animals, Cardiovascular Diseases, Disease Models, Animal, Humans, Inflammation, Periodontal Diseases, Rabbits, Evidence-Based Medicine

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