The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Brain opioids and mother—infant social motivation
Abstract
Brain opioids were the first neurochemical system to be implicated in the elaboration of socialbonding processes. Although a variety of neurochemical systems help elaborate social rewards and specific social behaviors, the role of opioids in the control of maternal behavior remains controversial. Although a great deal of data indicate that intermediate doses of morphine can reduce maternal behavior, the evidence, taken together, suggests that endogeneous opioids promote the regulatory control of maternal behavior, probably by providing feedback concerning the satisfaction that can be had from indulging in various maternal behaviors. Thus opioid blockade with naltrexone can reduce maternal competence in animals, while at the same time increasing maternal motivation. Opiate blockade likewise appears to increase the social motivation of rat pups, but reduces the reinforcing quality of interaction with the mother, suggesting that opioids provide feedback concerning the pleasurable qualities of social interaction in both mothers and infants. The clinical implications of this knowledge are not straightforward, but they generally suggest that clinically deficient social bonding might be capable of being strengthened via manipulation of brain opioid systems.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“These hedonic maternal response and behaviour-mediating brain circuits behaviours may be modulated by EO in a narrow physiological range by providing satisfaction feedback to augment reinforcement (59).”
From Neuroendocrinology of Parental Response to Baby‐Cry (2011) · cites this paper as [59]
Citations
Cites
The Physiology of Reproduction
Blandau, R. J. (1988) · JAMA · doi:10.1001/jama.1988.03410200127050 · Cited by 3,000
Endogenous opioids and social behavior
Panksepp, J., Herman, B. H., Vilberg, T., Bishop, P., & DeEskinazi, F. G. (1980) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(80)90036-6 · Cited by 531
Self-citationInsel, T. R. (1992) · Psychoneuroendocrinology · doi:10.1016/0306-4530(92)90073-g · Cited by 487
The psychobiology of play: Theoretical and methodological perspectives
Panksepp, J., Siviy, S., & Normansell, L. (1984) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(84)90005-8 · Cited by 468
Self-citationEndorphin-Mediated Increases in Pain Threshold During Pregnancy
Gintzler, A. R. (1980) · Science · doi:10.1126/science.7414330 · Cited by 341
Mammalian parenting; biochemical, neurobiological and behavioral determinants
(1991) · Comparative Biochemistry and Physiology Part A Physiology · doi:10.1016/0300-9629(91)90623-k · Cited by 196
The Physiological Control of Mammalian Vocalization
(1988) · Springer eBooks · doi:10.1007/978-1-4613-1051-8 · Cited by 180
Bridges, R. S., & Grimm, C. T. (1982) · Science · doi:10.1126/science.7123227 · Cited by 172
Opiates and play dominance in juvenile rats.
Panksepp, J., Jalowiec, J., DeEskinazi, F. G., & Bishop, P. (1985) · Behavioral Neuroscience · doi:10.1037/0735-7044.99.3.441 · Cited by 167
Self-citationOpiates and play dominance in juvenile rats.
Panksepp, J., Jalowiec, J. E., DeEskinazi, F. G., & Bishop, P. (1985) · Behavioral Neuroscience · doi:10.1037//0735-7044.99.3.441 · Cited by 167
Self-citation
Research works printed but not linked: 6
- Panksepp J., 1981, Progress in Theory in Psychopharmacology, 149
- Panksepp J., 1991, International Reviews of Emotion Research, 59
- Bridges RS., 1990, Mammalian Parenting, Biochemical, Neurobiological and Behavioral Determinants, 93
- Vilberg T, 1977, Possible relation between brain opiates and social behaviors, Neurosci Abstr, 3, 303
- Brown D, 1979, Effects of chronic opiate receptor antagonism by naltrexone on aspects of maternal behavior in mice, Neurosci Abstr, 5, 550
- Normansell L, 1982, Naloxone increases social need, Neurosci Abstr, 8, 592
Cited by
Sorted by citations
Infant Intersubjectivity: Research, Theory, and Clinical Applications
Trevarthen, C., & Aitken, K. J. (2001) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00701 · Cited by 1,694
Neuroendocrine perspectives on social attachment and love
Sue Carter, C. (1998) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(98)00055-9 · Cited by 1,425
“…endogenous opioids and prolactin affect parental behavior, possibly by modulating the rewarding aspects of this behavior (Panksepp, 1981; Panksepp et al., 1994, 1997), or by pacing of mother – infant interactions (Bridges, 1990), or through their documented abilities to influence the…”
depue, R. A., & morrone-strupinsky, J. V. (2005) · Behavioral and Brain Sciences · doi:10.1017/s0140525x05000063 · Cited by 958
“Such findings suggest that opiates provide a critical part of the neural basis on which primate sociality has evolved (Keverne et al. 1989; Nelson & Panksepp 1998; Panksepp et al. 1994).”
BackgroundInfluentialNelson, E. E., & Panksepp, J. (1998) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(97)00052-3 · Cited by 688
The Simulation of Smiles (SIMS) model: Embodied simulation and the meaning of facial expression
Niedenthal, P. M., Mermillod, M., Maringer, M., & Hess, U. (2010) · Behavioral and Brain Sciences · doi:10.1017/s0140525x10000865 · Cited by 618
Metadata
- Authors
- Panksepp, J., Nelson, E., & Siviy, S.
- Affiliations
- Bowling Green State University (US)
- Corresponding author
- Panksepp, Jaak
- ORCID
- Nelson, Eric
- Venue
- Acta Paediatrica
- Publisher
- Wiley
- Published
- 1994-06
- Volume
- 83
- Issue
- s397
- Pages
- 40-46
- ISSN
- 0365-1436 (ISSN-L)
- 0803-5253
- 1651-2227
- OpenAlex
- W1997676465
- Cited by
- 133
- References
- 26
- Citations by year
- 2025: 3 · 2024: 3 · 2023: 2 · 2022: 3 · 2021: 4 · 2020: 4 · 2019: 1 · 2018: 3 · 2017: 1 · 2016: 7 · 2015: 4 · 2014: 8 · 2013: 7 · 2012: 6
- FWCI
- 0.73
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Paediatrica (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (1r15hd030387-01)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (1 R15 HD 30387-01)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- endogenous opioids, maternal behavior, social motivation, morphine, naltrexone, opioid blockade, maternal competence, social reward, neonatal rats
- MeSH terms
- Animals, Biofeedback, Psychology, Female, Humans, Infant, Infant, Newborn, Maternal Behavior, Morphine, Mother-Child Relations, Motivation, Naltrexone, Object Attachment, Social Behavior
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
