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Phosphorylation of the Translational Repressor PHAS-I by the Mammalian Target of Rapamycin

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Regulation of eIF-4E BP1 Phosphorylation by mTOR

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Senegenin Inhibits Aβ1-42-Induced PC12 Cells Apoptosis and Oxidative Stress via Activation of the PI3K/Akt Signaling Pathway

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Structural Basis for the Recognition of Eukaryotic Elongation Factor 2 Kinase by Calmodulin

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Activation of mTOR signaling leads to orthopedic surgery-induced cognitive decline in mice through β-amyloid accumulation and tau phosphorylation

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Contribution of Energy Dysfunction to Impaired Protein Translation in Neurodegenerative Diseases

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The innate immune response in tauopathies

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Rescuing epileptic and behavioral alterations in a Dravet syndrome mouse model by inhibiting eukaryotic elongation factor 2 kinase (eEF2K)

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Noncanonical feedback loop between “RIP3–MLKL” and “4EBP1–eIF4E” promotes neuronal necroptosis

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Cooperation of cell adhesion and autophagy in the brain: Functional roles in development and neurodegenerative disease

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Residual microglia following short‐term PLX5622 treatment in 5xFAD mice exhibit diminished NLRP3 inflammasome and mTOR signaling, and enhanced autophagy

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Proteomic study of the toxic effect of oligomeric Aβ1-42 in situ prepared from ‘iso-Aβ1-42’

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Targeting impaired nutrient sensing with repurposed therapeutics to prevent or treat age-related cognitive decline and dementia: A systematic review

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Everolimus Shows Synergistic Antimyeloma Effects with Bortezomib via the AKT/mTOR Pathway

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An Analysis of Potential Surrogate Markers of Target-Specific Therapy in Archival Materials of Adrenocortical Carcinoma

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Prioritization of candidate disease genes by enlarging the seed set and fusing information of the network topology and gene expression

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Beyond the amyloid hypothesis: how current research implicates autoimmunity in Alzheimer’s disease pathogenesis

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Revealing brain mechanisms of mTOR-mediated translational regulation: Implications for chronic pain

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mTOR Mysteries: Nuances and Questions About the Mechanistic Target of Rapamycin in Neurodegeneration

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The effect of the type of dietary protein on the development of ovarian cancer

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Potentiation of Schaffer-Collateral CA1 Synaptic Transmission by eEF2K and p38 MAPK Mediated Mechanisms

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Aberrant DJ-1 expression underlies L-type calcium channel hypoactivity in dendrites in tuberous sclerosis complex and Alzheimer’s disease

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Inflammatory protein associations with brain MRI measures: Framingham Offspring Cohort

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Analysis of ribosomal protein S6 baseline phosphorylation and effect of tau pathology in the murine brain and human hippocampus

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Is the Brain Undernourished in Alzheimer’s Disease?

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Drug Target to Alleviate Mitochondrial Dysfunctions in Alzheimer’s Disease: Recent Advances and Therapeutic Implications

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Brain transcriptomes of zebrafish and mouse Alzheimer's disease knock-in models imply early disrupted energy metabolism

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4EBP-Dependent Signaling Supports West Nile Virus Growth and Protein Expression

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Translation from the Ribosome to the Clinic: Implication in Neurological Disorders and New Perspectives from Recent Advances

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PPAR Gamma Coactivator 1 Beta (PGC-1β) Reduces Mammalian Target of Rapamycin (mTOR) Expression via a SIRT1-Dependent Mechanism in Neurons

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Isoliquiritigenin attenuated cognitive impairment, cerebral tau phosphorylation and oxidative stress in a streptozotocin-induced mouse model of Alzheimer's disease

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The Inflammation-Induced Dysregulation of Reelin Homeostasis Hypothesis of Alzheimer’s Disease

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Deregulation of Mitochondrial Calcium Handling Due to Presenilin Loss Disrupts Redox Homeostasis and Promotes Neuronal Dysfunction

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Targeting autophagy in astrocytes: a potential for neurodegenerative disease intervention

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HSP70 interacts with Rheb, inhibiting mTORC1 signaling

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Amelioration of Behavioral Abnormalities in BH4-deficient Mice by Dietary Supplementation of Tyrosine

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Solution Structure of the Carboxy-Terminal Tandem Repeat Domain of Eukaryotic Elongation Factor 2 Kinase and Its Role in Substrate Recognition

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Role of PIM Kinase Inhibitor in the Treatment of Alzheimer’s Disease

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Polycystic kidney disease is significantly associated with dementia risk

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Mammalian target of rapamycin/p70 ribosomal S6 protein kinase signaling is altered by sevoflurane and/or surgery in aged rats.

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Unravelling the Alzheimer's pathogenesis: Molecular and cellular pathways to neurodegeneration and therapeutic targets

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Tortuous Paths of Insulin Signaling and Mitochondria in Alzheimer’s Disease

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A Tau-Driven Adverse Outcome Pathway Blueprint Toward Memory Loss in Sporadic (Late-Onset) Alzheimer’s Disease with Plausible Molecular Initiating Event Plug-Ins for Environmental Neurotoxicants

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Brain insulin resistance in Down syndrome: Involvement of PI3K-Akt/mTOR axis in early-onset of Alzheimer's disease and its potential as a therapeutic target

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One-Carbon Metabolism Alteration Affects Brain Proteome Profile in a Mouse Model of Alzheimer's Disease

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Thermal Injury Activates the eEF2K‐Dependent eEF2 Pathway in Pediatric Patients

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The 4E-BPs as Translational Regulators in Neurological Disorders: Molecular Mechanisms and Therapeutic Potential

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Presenilin-1 F105C mutation leads to tau accumulation in human neurons via the Akt/mTORC1 signaling pathway

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siRNA Blocking of Mammalian Target of Rapamycin (mTOR) Attenuates Pathology in Annonacin-Induced Tauopathy in Mice

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Role of FMRP in rapid antidepressant effects and synapse regulation

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The mTOR Signaling Pathway in Neurodegenerative Diseases

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Gamma Frequency Inhibits the Secretion and Aggregation of Amyloid-β and Decreases the Phosphorylation of mTOR and Tau Proteins in vitro

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Roles of AMP, ADP, ATP, and AMPK in Healthy Energy Boosting and Prolonged Life Span

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The mTOR Pathway and Aging

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Turning Back the Clock: A Retrospective Single-Blind Study on Brain Age Change in Response to Nutraceuticals Supplementation vs. Lifestyle Modifications

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Hearing modulation affects Alzheimer’s disease progression linked to brain inflammation: a study in mouse models

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Decoding the Inter-Relationship between Sleep Disorders and Alzheimer’s Disease Pathogenesis

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Transcriptional regulation of autophagy in aging

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Biomarker identification for diagnosis of Alzheimer's disease

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Structure of the C-Terminal Helical Repeat Domain of Eukaryotic Elongation Factor 2 Kinase

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Hippocampal mTOR Dysregulation and Morphological Changes in Male Rats after Fetal Growth Restriction

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The role of calcium in the interaction between calmodulin and a minimal functional construct of eukaryotic elongation factor 2 kinase

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Astrocyte biomarker signatures of amyloid-β and tau pathologies in Alzheimer’s diseasePreprint

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Landscape of Protein Post-Translational Modifications in Age-Related Neurodegenerative Disorders: Implications in Protein Aggregation, Altered Cellular Processes, and Therapeutics

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Detection of proteomic alterations at different stages in a Huntington's disease mouse model via matrix‐assisted laser desorption/ionization mass spectrometry (MALDI‐MS) imaging

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Indole and Coumarin Derivatives Targeting EEF2K in Aβ Folding Reporter Cells

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Dysregulation of Neuronal Protein Synthesis in Alzheimer’s Disease

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The identities of insulin signaling pathway are affected by overexpression of Tau and its phosphorylation form

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Autophagie et cerveau

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Synthesis of novel triazole-urea hybrids and their antiproliferative activity against pancreatic cancer through suppression of eEF2K and induction of apoptosis

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Role of Tau Protein Hyperphosphorylation in Diabetic Retinal Neurodegeneration

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Aging and the Brain

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The multifaceted role of mitochondrial dysfunction in Alzheimer’s disease pathogenesis

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Correlation of autophagy and Alzheimer's disease with special emphasis on the role of phosphodiesterase-4

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Nutrient sensing receptor GPRC6A regulates mTORC1 signaling and Tau biology

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Targeted downregulation of insulin signaling restricts human tau pathogenesis by reinstating the aberrant heterochromatin loss and mTOR/4EBP/S6K pathway in Drosophila

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Modern Concepts of Alzheimer,s Disease Pathogenesis: Novel Approaches to Pharmacotherapy (Review)

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Causal Association Between mTOR-Dependent Protein Levels and Alzheimer’s Disease: A Mendelian Randomization Study

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