The DOI matches its Crossref record; 94 of the 94 references it cites were found in a registry or an index.
Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine‐rich proteoglycans
Open accessAbstract
The small leucine‐rich proteoglycans (SLRPs) are involved in many aspects of mammalian biology, both in health and disease. They are now being recognized as key signaling molecules with an expanding repertoire of molecular interactions affecting not only growth factors, but also various receptors involved in controlling cell growth, morphogenesis and immunity. The complexity of SLRP signaling and the multitude of affected signaling pathways can be reconciled with a hierarchical affinity‐based interaction of various SLRPs in a cell‐ and tissue‐specific context. Here, we review this interacting network, describe new relationships of the SLRPs with tyrosine kinase and Toll‐like receptors and critically assess their roles in cancer and innate immunity.
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Cites
MATRIX PROTEOGLYCANS: From Molecular Design to Cellular Function
Iozzo, R. V. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.609 · Cited by 1,637
Self-citationNegative regulation of transforming growth factor-β by the proteoglycan decorin
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Targeted Disruption of Decorin Leads to Abnormal Collagen Fibril Morphology and Skin Fragility
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Self-citationThe Biology of the Small Leucine-rich Proteoglycans
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Self-citationBiological Functions of the Small Leucine-rich Proteoglycans: From Genetics to Signal Transduction
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Self-citationProteoglycans: from structural compounds to signaling molecules
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Klingberg, F., Hinz, B., & White, E. S. (2013) · The Journal of Pathology · doi:10.1002/path.4104 · Cited by 776
Glycosaminoglycans: key players in cancer cell biology and treatment
Afratis, N., Gialeli, C., Nikitovic, D., Tsegenidis, T., Karousou, E., Theocharis, A. D., Pavão, M. S., Tzanakakis, G. N., & Karamanos, N. K. (2012) · The FEBS Journal · doi:10.1111/j.1742-4658.2012.08529.x · Cited by 554
Theocharis, A. D., Skandalis, S. S., Tzanakakis, G. N., & Karamanos, N. K. (2010) · The FEBS Journal · doi:10.1111/j.1742-4658.2010.07800.x · Cited by 403
Myocardial Extracellular Matrix: An Ever-Changing and Diverse Entity
Rienks, M., Papageorgiou, A.-P., Frangogiannis, N. G., & Heymans, S. (2014) · Circulation Research · doi:10.1161/circresaha.114.302533 · Cited by 366
Merline, R., Moreth, K., Beckmann, J., Nastase, M. V., Zeng-Brouwers, J., Tralhão, J. G., Lemarchand, P., Pfeilschifter, J., Schaefer, R. M., Iozzo, R. V., et al. (2011) · Science Signaling · doi:10.1126/scisignal.2001868 · Cited by 333
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Metadata
- Authors
- Iozzo, R. V., & Schaefer, L.
- Venue
- The FEBS Journal
- Publisher
- Wiley
- Published
- 2010-08-31
- Volume
- 277
- Issue
- 19
- Pages
- 3864-3875
- ISSN
- 1742-464X (ISSN-L)
- 1742-4658
- OpenAlex
- W1598189106
- Cited by
- 292
- References
- 94
- FWCI
- 13.16
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
