Physical exercise and brain monoamines: a review.
Abstract
A review of the literature on the relationship of exercise to mental health strongly suggests that the two are closely linked. Thus, physical activity has been reported to reduce depression symptoms and anxiety, and to improve coping with stress. Logically, many investigators have then tried to determine the physiological mechanisms that are responsible for this mood-elevating effect of exercise. Among the current hypotheses, those regarding the endorphin and the monoamine systems have received a great deal of attention. On that basis, the respective effects of physical exercise on brain dopamine, noradrenaline and serotonin transmission are reviewed herein. In addition, suggestions are advanced for future research in this field.
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AE is thought to interact with several neurotransmitter systems, including the monoamine system.
“In addition to promoting neuroplastic changes that could lead to cognitive enhancement, AE is also thought to interact with several neurotransmitter systems, including the monoamine system (Chaouloff, 1989).”
From Aerobic Exercise as a Tool to Improve Hippocampal Plasticity and Function in Humans: Practical Implications for Mental Health Treatment (2016) · cites this paper as Chaouloff, 1989
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- Authors
- CHAOULOFF, F.
- Affiliations
- Inserm (FR)
- Corresponding author
- CHAOULOFF, F.
- ORCID
- CHAOULOFF, F.
- Venue
- Acta Physiologica Scandinavica
- Publisher
- Wiley
- Published
- 1989-09
- Volume
- 137
- Issue
- 1
- Pages
- 1-13
- ISSN
- 0001-6772 (ISSN-L)
- 1365-201X
- OpenAlex
- W1972286845
- Cited by
- 316
- References
- 94
- Citations by year
- 2026: 5 · 2025: 5 · 2024: 5 · 2023: 4 · 2022: 10 · 2021: 7 · 2020: 10 · 2019: 10 · 2018: 11 · 2017: 6 · 2016: 11 · 2015: 11 · 2014: 6 · 2013: 14 · 2012: 13
- FWCI
- 0.76
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Acta Physiologica Scandinavica (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- physical activity, brain monoamines, dopamine, norepinephrine, serotonin, endorphins, exercise and mental health, depression, anxiety, stress coping, neurotransmission
- MeSH terms
- Brain, Dopamine, Humans, Mental Health, Norepinephrine, Serotonin, Biogenic Monoamines, Exercise
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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