On the Effects of Glucagon-Like Peptide-1 on Blood Glucose Regulation in Normal and Diabetic Subjects

Glucagon-like peptide-1 7–36: a physiological incretin in man

Kreymann, B., Ghatei, M. A., Williams, G., & Bloom, S. R. (1987) · The Lancet · doi:10.1016/s0140-6736(87)91194-9 · Cited by 1,928 · see citing works

Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

Nauck, M. A., Heimesaat, M. M., Orskov, C., Holst, J. J., Ebert, R., & Creutzfeldt, W. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116186 · Cited by 1,651 · see citing works

Normalization of fasting hyperglycaemia by exogenous glucagon-like peptide 1 (7-36 amide) in Type 2 (non-insulin-dependent) diabetic patients

Nauck, M. A., Kleine, N., �rskov, C., Holst, J. J., Willms, B., & Creutzfeldt, W. (1993) · Diabetologia · doi:10.1007/bf00401145 · Cited by 1,092 · see citing works

Tissue and Plasma Concentrations of Amidated and Glycine-Extended Glucagon-Like Peptide I in Humans

Ørskov, C., Rabenhøj, L., Wettergren, A., Kofod, H., & Holst, J. J. (1994) · Diabetes · doi:10.2337/diab.43.4.535 · Cited by 916 · see citing works

Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1.

Thorens, B. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.18.8641 · Cited by 906 · see citing works

Insulinotropin: glucagon-like peptide I (7-37) co-encoded in the glucagon gene is a potent stimulator of insulin release in the perfused rat pancreas.

Mojsov, S., Weir, G. C., & Habener, J. F. (1987) · Journal of Clinical Investigation · doi:10.1172/jci112855 · Cited by 882 · see citing works

Both Subcutaneously and Intravenously Administered Glucagon-Like Peptide I Are Rapidly Degraded From the NH2-Terminus in Type II Diabetic Patients and in Healthy Subjects

Deacon, C. F., Nauck, M. A., Toft-Nielsen, M.-B., Pridal, L., Willms, B., & Holst, J. J. (1995) · Diabetes · doi:10.2337/diabetes.44.9.1126 · Cited by 878 · see citing works

Antidiabetogenic effect of glucagon-like peptide-1 (7–36)amide in normal subjects and patients with diabetes mellitus

Gutniak, M., Ørkov, C., Holst, J. J., Ahrén, B., & Efendić, S. (1992) · New England Journal of Medicine · doi:10.1056/nejm199205143262003 · Cited by 868 · see citing works

Degradation of glucagon-like peptide-1 by human plasma in vitro yields an N-terminally truncated peptide that is a major endogenous metabolite in vivo.

Deacon, C. F., Johnsen, A. H., & Holst, J. J. (1995) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.80.3.7883856 · Cited by 792 · see citing works

Preproglucagon gene expression in pancreas and intestine diversifies at the level of post-translational processing

Mojsov, S., Heinrich, G., Wilson, I. B., Ravazzola, M., Orci, L., & Habener, J. F. (1986) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)67324-7 · Cited by 724 · see citing works

Glucagon-like peptide-1(7–36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns

Elliott, R. M., Morgan, L. M., Tredger, J. A., Deacon, S., Wright, J., & Marks, V. (1993) · Journal of Endocrinology · doi:10.1677/joe.0.1380159 · Cited by 695 · see citing works

Truncated GLP-1 (proglucagon 78?107-amide) inhibits gastric and pancreatic functions in man

Wettergren, A., Schjoldager, B., Mortensen, P. E., Myhre, J., Christiansen, J., & Holst, J. J. (1993) · Digestive Diseases and Sciences · doi:10.1007/bf01316798 · Cited by 670 · see citing works

Glucagon‐like peptide‐1 cells in the gastrointestinal tract and pancreas of rat, pig and man

EISSELE, R., GÖKE, R., WILLEMER, S., HARTHUS, H. ‐., VERMEER, H., ARNOLD, R., & GÖKE, B. (1992) · European Journal of Clinical Investigation · doi:10.1111/j.1365-2362.1992.tb01464.x · Cited by 654 · see citing works

Hamster preproglucagon contains the sequence of glucagon and two related peptides

Bell, G. I., Santerre, R. F., & Mullenbach, G. T. (1983) · Nature · doi:10.1038/302716a0 · Cited by 649 · see citing works

Truncated glucagon‐like peptide I, an insulin‐releasing hormone from the distal gut

Holst, J. J., Ørskov, C., Nielsen, O. V., & Schwartz, T. W. (1987) · FEBS Letters · doi:10.1016/0014-5793(87)81430-8 · Cited by 611 · see citing works

Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37)

Holz, G. G., Kiihtreiber, W. M., & Habener, J. F. (1993) · Nature · doi:10.1038/361362a0 · Cited by 594 · see citing works

Exon duplication and divergence in the human preproglucagon gene

Bell, G. I., Sanchez-Pescador, R., Laybourn, P. J., & Najarian, R. C. (1983) · Nature · doi:10.1038/304368a0 · Cited by 593 · see citing works

Cell and Molecular Biology of the Incretin Hormones Glucagon-Like Peptide-I and Glucose-Dependent Insulin Releasing Polypeptide

Fehmann, H. C., Göke, R., & Göke, B. (1995) · Endocrine Reviews · doi:10.1210/edrv-16-3-390 · Cited by 527 · see citing works

Glucagon-Like Peptides GLP-1 and GLP-2, Predicted Products of the Glucagon Gene, Are Secreted Separately from Pig Small Intestine but Not Pancreas*

Ørskov, C., Holst, J. J., Knuhtsen, S., Baldissera, F. G. A., Poulsen, S. S., & Nielsen, O. V. (1986) · Endocrinology · doi:10.1210/endo-119-4-1467 · Cited by 484 · see citing works

Effect of Truncated Glucagon-Like Peptide-1 [Proglucagon-(78–107) amide] on Endocrine Secretion from Pig Pancreas, Antrum, and Nonantral Stomach

Ørskov, C., Holst, J. J., & Nielsen, O. V. (1988) · Endocrinology · doi:10.1210/endo-123-4-2009 · Cited by 400 · see citing works

Biological Effects and Metabolic Rates of Glucagonlike Peptide-1 7–36 Amide and Glucagonlike Peptide-1 7–37 in Healthy Subjects Are Indistinguishable

Ørskov, C., Wettergren, A., & Holst, J. J. (1993) · Diabetes · doi:10.2337/diab.42.5.658 · Cited by 318 · see citing works

Glucagon-like peptide 1 enhances glucose tolerance both by stimulation of insulin release and by increasing insulin-independent glucose disposal.

D'Alessio, D., Kahn, S., Leusner, C. R., & Ensinck, J. (1994) · Journal of Clinical Investigation · doi:10.1172/jci117225 · Cited by 309 · see citing works

Glucagon-Like Peptide I Receptors in the Subfornical Organ and the Area Postrema Are Accessible to Circulating Glucagon-Like Peptide I

Ørskov, C., Poulsen, S. S., Mørten, M., & Holst, J. J. (1996) · Diabetes · doi:10.2337/diab.45.6.832 · Cited by 303 · see citing works

Glucagonlike peptide 1: a newly discovered gastrointestinal hormone

Holst, J. J. (1994) · Gastroenterology · doi:10.1016/0016-5085(94)90831-1 · Cited by 252 · see citing works

Ileal release of glucagon-like peptide-1 (GLP-1)

Layer, P., Holst, J. J., Grandt, D., & Goebell, H. (1995) · Digestive Diseases and Sciences · doi:10.1007/bf02064202 · Cited by 216 · see citing works

The primary structure of porcine glicentin (proglucagon)

Thim, L., & Moody, A. J. (1981) · Regulatory Peptides · doi:10.1016/0167-0115(81)90007-0 · Cited by 216 · see citing works

Complete Sequences of Glucagon-like Peptide-1 from Human and Pig Small Intestine

Ørskov, C., Bersani, M., Johnsen, A. H., Højrup, P., & Holst, J. J. (1989) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)51561-1 · Cited by 210 · see citing works

Pharmacokinetic, insulinotropic, and glucagonostatic properties of GLP-1 [7?36 amide] after subcutaneous injection in healthy volunteers. Dose-response-relationships

Ritzel, R. A., �rskov, C., Holst, J. J., & Nauck, M. A. (1995) · Diabetologia · doi:10.1007/bf00401846 · Cited by 210 · see citing works

Effect of glucagon-like peptide-1 (proglucagon 78-107amide) on hepatic glucose production in healthy man

Hvidberg, A., Nielsen, M.-B., Hilsted, J., Ørskov, C., & Holst, J. J. (1994) · Metabolism · doi:10.1016/0026-0495(94)90164-3 · Cited by 195 · see citing works

Activation of a cAMP-regulated Ca2+-Signaling Pathway in Pancreatic β-Cells by the Insulinotropic Hormone Glucagon-like Peptide-1

Holz, G. G., Leech, C. A., & Habener, J. F. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.30.17749 · Cited by 188 · see citing works

Reduction of the Incretin Effect in Rats by the Glucagon-Like Peptide 1 Receptor Antagonist Exendin (9–39) Amide

Kolligs, F. T., Fehmann, H.-C., Göke, R., & Göke, B. (1995) · Diabetes · doi:10.2337/diab.44.1.16 · Cited by 185 · see citing works

Proglucagon processing in porcine and human pancreas.

Holst, J. J., Bersani, M., Johnsen, A. H., Kofod, H., Hartmann, B., & Ørskov, C. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)32241-x · Cited by 181 · see citing works

GLP-1 (glucagon-like peptide 1) and truncated GLP-1, fragments of human proglucagon, inhibit gastric acid secretion in humans

Schjoldager, B., Mortensen, P. E., Christiansen, J., �rskov, C., & Holst, J. J. (1989) · Digestive Diseases and Sciences · doi:10.1007/bf01540341 · Cited by 178 · see citing works

Evidence that enteroglucagon (II) is identical with the C-terminal sequence (residues 33-69) of glicentin

Holst, J. J. (1982) · Biochemical Journal · doi:10.1042/bj2070381 · Cited by 177 · see citing works

Isolation of glucagon‐37 (bioactive enteroglucagon/oxyntomodulin) from porcine jejuno‐ileum

BATAILLE, D., Coudray, A. M., Carlqvist, M., Rosselin, G., & Mutt, V. (1982) · FEBS Letters · doi:10.1016/0014-5793(82)80708-4 · Cited by 162 · see citing works

Isolation of glucagon‐37 (bioactive enteroglucagon/oxyntomodulin) from porcine jejuno‐ileum

BATAILLE, D., Tatemoto, K., Gespach, C. P., Jörnvall, H., Rosselin, G., & Mutt, V. (1982) · FEBS Letters · doi:10.1016/0014-5793(82)80709-6 · Cited by 151 · see citing works

Glucagon-Like Peptide-1 7-36 Amide and Peptide YY from the L-Cell of the Ileal Mucosa Are Potent Inhibitors of Vagally Induced Gastric Acid Secretion in Man

Wettergren, A., Petersen, H., ørskov, C., Christiansen, J., Sheikh, S. P., & Holst, J. J. (1994) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529409092462 · Cited by 133 · see citing works

Identical mRNA for preproglucagon in pancreas and gut

Novak, U., Wilks, A. F., Buell, G. N., & McEwen, S. J. (1987) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1987.tb11162.x · Cited by 125 · see citing works

Glucagon-Like Peptide I Increases Cytoplasmic Calcium in Insulin-Secreting βTC3-Cells by Enhancement of Intracellular Calcium Mobilization

Gromada, J., Dissing, S., Bokvist, K., Renström, E., Frøkjær-Jensen, J., Wulff, B. S., & Rorsman, P. (1995) · Diabetes · doi:10.2337/diab.44.7.767 · Cited by 125 · see citing works

Evidence that glicentin contains the entire sequence of glucagon

Holst, J. J. (1980) · Biochemical Journal · doi:10.1042/bj1870337 · Cited by 122 · see citing works

Gut glucagon, enteroglucagon, gut glucagonlike immunoreactivity, glicentin—Current status

Holst, J. J. (1983) · Gastroenterology · doi:10.1016/0016-5085(83)90388-8 · Cited by 117 · see citing works

GLP-1 does not acutely affect insulin sensitivity in healthy man

Ørskov, L., Holst, J. J., Møller, J., Ørskov, C., Møller, N., Alberti, K. G. M. M., & Schmitz, O. (1996) · Diabetologia · doi:10.1007/bf02658511 · Cited by 114 · see citing works

Oxyntomodulin (glicentin-(33–69)): pharmacokinetics, binding to liver cell membranes, effects on isolated perfused pig pancreas, and secretion from isolated perfused lower small intestine of pigs

Baldissera, F. G. A., Holst, J. J., Knuhtsen, S., Hilsted, L., & Nielsen, O. V. (1988) · Regulatory Peptides · doi:10.1016/0167-0115(88)90099-7 · Cited by 114 · see citing works

Insulinotropic actions of intravenous glucagon-like peptide-1 (GLP-1) [7?36 amide] in the fasting state in healthy subjects

Qualmann, C., Nauck, M. A., Holst, J. J., �rskov, C., & Creutzfeldt, W. (1995) · Acta Diabetologica · doi:10.1007/bf00581038 · Cited by 101 · see citing works

Relationship of glicentin to proglucagon and glucagon in the porcine pancreas

Moody, A. J., Holst, J. J., Thim, L., & Jensen, S. L. (1981) · Nature · doi:10.1038/289514a0 · Cited by 100 · see citing works

The Effect of Glucagon-Like Peptide I (GLP-I) on Glucose Elimination in Healthy Subjects Depends on the Pancreatic Glucoregulatory Hormones

Toft-Nielson, M.-B., Madsbad, S., & Holst, J. J. (1996) · Diabetes · doi:10.2337/diab.45.5.552 · Cited by 99 · see citing works

Gut Peptides: Biochemistry and Physiology

Rehfeld, J. F. (1994) · Gut · doi:10.1136/gut.35.12.1774 · Cited by 88 · see citing works

Naturally occurring products of proglucagon 111-160 in the porcine and human small intestine.

Buhl, T., Thim, L., Kofod, H., Ørskov, C., Harling, H., & Holst, J. J. (1988) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)68350-4 · Cited by 72 · see citing works

Purification and chemical characterization of a glicentin-related pancreatic peptide (proglucagon fragment) from porcine pancreas

Thim, L., & Moody, A. J. (1982) · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · doi:10.1016/0167-4838(82)90041-3 · Cited by 58 · see citing works

Carboxypeptidase‐B‐like processing of the C‐terminus of glucagon‐like peptide‐2 in pig and human small intestine

Ørskov, C., Buhl, T., Rabenhøj, L., Kofod, H., & Holst, J. J. (1989) · FEBS Letters · doi:10.1016/0014-5793(89)81332-8 · Cited by 23 · see citing works

Activity of oxyntomodulin on gastric acid secretion induced by histamine or a meal in the rat

Jarrousse, C., Carles-Bonnet, C., Niel, H., et al. (1994) · Peptides · doi:10.1016/0196-9781(94)90117-1 · Cited by 13 · see citing works

In vitro insulinomimetric effects of GLP‐1 in liver, muscle and fat

Valverde, I., & Villanueva‐Peñacarrillo, M. L. (1996) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.1996.43257000.x · Cited by 12 · see citing works

A model of GLP-1 action on insulin secretion in nondiabetic subjects

Dalla Man, C., Micheletto, F., Sathananthan, A., Rizza, R. A., Vella, A., & Cobelli, C. (2010) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00705.2009 · Cited by 45 · see citing works

Model-Based Quantification of Glucagon-Like Peptide-1–Induced Potentiation of Insulin Secretion in Response to a Mixed Meal Challenge

Dalla Man, C., Micheletto, F., Sathananthan, M., Vella, A., & Cobelli, C. (2016) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2015.0146 · Cited by 24 · see citing works

DETERMINING QUALITY REQUIREMENTS AT THE UNIVERSITIES TO IMPROVE THE QUALITY OF EDUCATION

Mustafa, N. H., Kelesbayev, D., & Alibekova, Z. D. (2018) · The Journal of Economic Research & Business Administration · doi:10.26577/be-2018-2-2141

Susquehanna Chorale Spring Concert "Roots and Wings"

Hawkins, D. (2017)

Genentech taps Affimed’s antibodies

Cross, R. (2018) · C&EN Global Enterprise · doi:10.1021/cen-09635-buscon15

Enxerto livre de arteria epigastrica inferior: avaliacao hemodinamica e angiografica pre e pos-operatoria

Dib, A., Puig, L. B., Salvadori, D., et al. (1988) · Arquivos Brasileiros de Cardiologia

Interleucinas na encefalopatia hipóxico-isquêmica

Ceccon, M. E. J. R. (2003) · Jornal de Pediatria · doi:10.1590/s0021-75572003000400002 · Cited by 14 · see citing works