The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention: Nutrition Reviews©, Vol. 66, No. s2
Abstract
The human vitamin D receptor (VDR) is a key nuclear receptor that binds nutritionally derived ligands and exerts bioeffects that contribute to bone mineral homeostasis, detoxification of exogenous and endogenous compounds, cancer prevention, and mammalian hair cycling. Liganded VDR modulates gene expression via heterodimerization with the retinoid X receptor and recruitment of coactivators or corepressors. VDR interacts with the corepressor hairless (Hr) to control hair cycling, an action independent of the endocrine VDR ligand, 1,25-dihydroxyvitamin D(3). We report novel dietary ligands for VDR including curcumin, gamma-tocotrienol, and essential fatty acid derivatives that likely play a role in the bioactions of VDR.
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Cites
Toll-Like Receptor Triggering of a Vitamin D-Mediated Human Antimicrobial Response
Liu, P. T., Stenger, S., Li, H., Wenzel, L., Tan, B. H., Krutzik, S. R., Ochoa, M. T., Schauber, J., Wu, K., Meinken, C., et al. (2006) · Science · doi:10.1126/science.1123933 · Cited by 3,924
Vitamin D Receptor As an Intestinal Bile Acid Sensor
Makishima, M., Lu, T. T., Xie, W., Whitfield, G. K., Domoto, H., Evans, R. M., Haussler, M. R., & Mangelsdorf, D. J. (2002) · Science · doi:10.1126/science.1070477 · Cited by 1,176
Self-citationWise, a context-dependent activator and inhibitor of Wnt signalling
Itasaki, N., Jones, C. M., Mercurio, S., Rowe, A., Domingos, P. M., Smith, J. C., & Krumlauf, R. (2003) · Development · doi:10.1242/dev.00674 · Cited by 321
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Cited by
Molecular Mechanisms of Vitamin D Action
Haussler, M. R., Whitfield, G. K., Kaneko, I., Haussler, C. A., Hsieh, D., Hsieh, J.-C., & Jurutka, P. W. (2013) · Calcified Tissue International · doi:10.1007/s00223-012-9619-0 · Cited by 759
Self-citationWang, J., Thingholm, L. B., Skiecevičienė, J., Rausch, P., Kummen, M., Hov, J. R., Degenhardt, F., Heinsen, F.-A., Rühlemann, M. C., Szymczak, S., et al. (2016) · Nature Genetics · doi:10.1038/ng.3695 · Cited by 625
Vitamin D hormone regulates serotonin synthesis. Part 1: Relevance for autism
Patrick, R. P., & Ames, B. N. (2014) · The FASEB Journal · doi:10.1096/fj.13-246546 · Cited by 414
Dzik, K. P., & Kaczor, J. J. (2019) · European Journal of Applied Physiology · doi:10.1007/s00421-019-04104-x · Cited by 357
Inflammation and vitamin D: The infection connection
Mangin, M., Sinha, R., & Fincher, K. (2014) · Inflammation Research · doi:10.1007/s00011-014-0755-z · Cited by 274
Neme, A., Seuter, S., & Carlberg, C. (2017) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2017.07.002 · Cited by 64
Metadata
- Authors
- Haussler, M. R., Haussler, C. A., Bartik, L., Whitfield, G. K., Hsieh, J.-C., Slater, S., & Jurutka, P. W.
- Venue
- Nutrition Reviews
- Publisher
- Oxford University Press (OUP)
- Published
- 2008-09-25
- Volume
- 66
- Issue
- 10 Suppl 2
- Pages
- S98-S112
- ISSN
- 0029-6643 (ISSN-L)
- OpenAlex
- W2151289341
- Cited by
- 320
- References
- 4
- FWCI
- 12.01
- Type
- journal article
- Language
- en
- Open access
- closed
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