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Using DGGE profiling to develop a novel culture medium suitable for oral microbial communities: DGGE profiling for culture medium development
Open accessAbstract
More than 700 bacterial species have been detected in the human oral cavity. They form highly organized microbial communities and are responsible for many oral infectious diseases, such as dental caries and periodontal disease. The prevention and treatment of these diseases require a comprehensive knowledge of oral microbial communities, which largely relies on culture-dependent methods to provide detailed phenotypic and physiological analysis of these communities. However, most of the currently available laboratory media can only selectively support the growth of a limited number of bacterial species within these communities, and fail to sustain the original oral microbial diversity. In this study, using denaturing gradient gel electrophoresis (DGGE) as an index to systematically survey and analyse the selectivity of commonly used laboratory media, we developed a new medium (SHI medium) by combining the ingredients of several selected media that can support different subpopulations within the original oral microbial community derived from pooled saliva. DGGE and 454 pyrosequencing analysis showed that SHI medium was capable of supporting a more diversified community with a microbial profile closer to that of the original oral microbiota. Furthermore, 454 pyrosequencing revealed that SHI medium supported the growth of many oral species that have not before been cultured. Crystal violet assay and the confocal laser scanning microscope analysis indicated that, compared with other media, SHI medium is able to support a more complex saliva-derived biofilm with higher biomass yield and more diverse species. This DGGE-guided method could also be used to develop novel media for other complex microbial communities.
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“In vitro biofilm culture systems using human saliva or defined media have served as a useful surrogate for oral biofilm research and have shed light on the mechanisms involved in microbial adherence, species interactions, antibiofilm treatments, and organization of the microbial community.55, 56, 57, 58, 59”
From The oral microbiome: Role of key organisms and complex networks in oral health and disease (2021) · cites this paper as [59]
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Cites
Naive Bayesian Classifier for Rapid Assignment of rRNA Sequences into the New Bacterial Taxonomy
Wang, Q., Garrity, G. M., Tiedje, J. M., & Cole, J. R. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00062-07 · Cited by 20,145
Muyzer, G., de Waal, E. C., & Uitterlinden, A. G. (1993) · Applied and Environmental Microbiology · doi:10.1128/aem.59.3.695-700.1993 · Cited by 11,490
The Ribosomal Database Project: improved alignments and new tools for rRNA analysis
Cole, J. R., Wang, Q., Cardenas, E., Fish, J., Chai, B., Farris, R. J., Kulam-Syed-Mohideen, A. S., McGarrell, D. M., Marsh, T. L., Garrity, G. M., et al. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn879 · Cited by 4,873
Defining the normal bacterial flora of the oral cavity
Aas, J. A., Paster, B. J., Stokes, L. N., Olsen, I., & Dewhirst, F. E. (2005) · Journal of Clinical Microbiology · doi:10.1128/jcm.43.11.5721-5732.2005 · Cited by 3,092
Edwards, U., Rogall, T., Blöcker, H., Emde, M., & Böttger, E. C. (1989) · Nucleic Acids Research · doi:10.1093/nar/17.19.7843 · Cited by 2,766
Liu, W., Marsh, T. L., Cheng, H. H., & Forney, L. J. (1997) · Applied and Environmental Microbiology · doi:10.1128/aem.63.11.4516-4522.1997 · Cited by 2,252
Quantification of biofilm structures by the novel computer program comstat
Heydorn, A., Nielsen, A. T., Hentzer, M., Sternberg, C., Givskov, M., Ersbøll, B. K., & Molin, S. (2000) · Microbiology · doi:10.1099/00221287-146-10-2395 · Cited by 2,185
Occlusal Caries: Biological Approach for Its Diagnosis and Management
Carvalho, J. C., Dige, I., Mačhiulskienė, V., Qvist, V., Bakhshandeh, A., Parolo, C. C. F., & Maltz, M. (2016) · Caries Research · doi:10.1159/000448662 · Cited by 2,159
Bacterial Diversity in Human Subgingival Plaque
Paster, B. J., Boches, S. K., Galvin, J. L., Ericson, R. E., Lau, C. N., Levanos, V. A., Sahasrabudhe, A., & Dewhirst, F. E. (2001) · Journal of Bacteriology · doi:10.1128/jb.183.12.3770-3783.2001 · Cited by 2,008
Oral multispecies biofilm development and the key role of cell–cell distance
Kolenbrander, P. E., Palmer, R. J., Periasamy, S., & Jakubovics, N. S. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2381 · Cited by 1,309
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He, X., McLean, J. S., Edlund, A., Yooseph, S., Hall, A. P., Liu, S.-Y., Dorrestein, P. C., Esquenazi, E., Hunter, R. C., Cheng, G., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1419038112 · Cited by 525
Self-citationThe bright side of microbial dark matter: lessons learned from the uncultivated majority.
Solden, L., Lloyd, K., & Wrighton, K. (2016) · Current Opinion in Microbiology · doi:10.1016/j.mib.2016.04.020 · Cited by 253
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Precision-guided antimicrobial peptide as a targeted modulator of human microbial ecology
Guo, L., McLean, J. S., Yang, Y., Eckert, R., Kaplan, C. W., Kyme, P., Sheikh, O., Varnum, B., Lux, R., Shi, W., et al. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1506207112 · Cited by 172
Self-citationvan Reenen, C. A., & Dicks, L. M. T. (2011) · Archives of Microbiology · doi:10.1007/s00203-010-0668-3 · Cited by 167
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Daubert, D. M., & Weinstein, B. F. (2019) · Periodontology 2000 · doi:10.1111/prd.12280 · Cited by 162
Edlund, A., Yang, Y., Hall, A. P., Guo, L., Lux, R., He, X., Nelson, K. E., Nealson, K. H., Yooseph, S., Shi, W., et al. (2013) · Microbiome · doi:10.1186/2049-2618-1-25 · Cited by 147
Self-citationCandida albicans promotes tooth decay by inducing oral microbial dysbiosis
Du, Q., Ren, B., He, J., Peng, X., Guo, Q., Zheng, L., Li, J., Dai, H., Chen, V., Zhang, L., et al. (2020) · The ISME Journal · doi:10.1038/s41396-020-00823-8 · Cited by 152
de Ávila, É. D., Lima, B. P., Sekiya, T., Torii, Y., Ogawa, T., Shi, W., & Lux, R. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.07.030 · Cited by 141
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Self-citationDu, Q., Fu, M., Zhou, Y., Cao, Y., Guo, T., Zhou, Z., Li, M., Peng, X., Zheng, X. M., Li, Y., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-59733-6 · Cited by 86
Edlund, A., Yang, Y., Yooseph, S., Hall, A. P., Nguyen, D. D., Dorrestein, P. C., Nelson, K. E., He, X., Lux, R., Shi, W., et al. (2015) · The ISME Journal · doi:10.1038/ismej.2015.72 · Cited by 84
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Self-citationChugal, N. M., Wang, J.-K., Wang, R., He, X., Kang, M., Li, J., Zhou, X., Shi, W., & Lux, R. (2011) · Journal of Endodontics · doi:10.1016/j.joen.2011.06.020 · Cited by 69
Self-citationKoopman, J. E., Buijs, M. J., Brandt, B. W., Keijser, B. J. F., Crielaard, W., & Zaura, E. (2016) · Microbial Ecology · doi:10.1007/s00248-016-0775-z · Cited by 66
He, X., Hu, W., Kaplan, C. W., Guo, L., Shi, W., & Lux, R. (2011) · Microbial Ecology · doi:10.1007/s00248-011-9989-2 · Cited by 64
Self-citationMuñoz‐González, C., Cueva, C., Pozo‐Bayón, M. Á., & Moreno-Arribas, M. V. (2015) · Food Chemistry · doi:10.1016/j.foodchem.2015.04.068 · Cited by 64
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Kotsakis, G. A., Black, R. M., Kum, J., Berbel, L. O., Sadr, A., Karoussis, I. K., Simopoulou, M., & Daubert, D. M. (2020) · Journal of Periodontology · doi:10.1002/jper.20-0186 · Cited by 59
Edlund, A., Yang, Y., Yooseph, S., He, X., Shi, W., & McLean, J. S. (2018) · Microbiome · doi:10.1186/s40168-018-0591-4 · Cited by 57
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Koopman, J., Röling, W., Buijs, M., Sissons, C., ten Cate, J. M., Keijser, B., Crielaard, W., & Zaura, E. (2014) · Microbial Ecology · doi:10.1007/s00248-014-0535-x · Cited by 58
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Self-citationLuo, T. L., Vanek, M. E., González‐Cabezas, C., Marrs, C. F., Foxman, B., & Rickard, A. H. (2021) · Journal of Applied Microbiology · doi:10.1111/jam.15200 · Cited by 43
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Lima, B. P., Hu, L. I., Vreeman, G. W., Weibel, D. B., & Lux, R. (2018) · Microbial Ecology · doi:10.1007/s00248-018-1291-0 · Cited by 35
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Edlund, A., Garg, N., Mohimani, H., Gurevich, A. A., He, X., Shi, W., Dorrestein, P. C., & McLean, J. S. (2017) · mSystems · doi:10.1128/msystems.00058-17 · Cited by 34
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Self-citationNeyraud, E., & Morzel, M. (2018) · Journal of Texture Studies · doi:10.1111/jtxs.12363 · Cited by 32
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Chen, Y., Agnello, M., Dinis, M., Chien, K. C., Wang, J., Hu, W., Shi, W., He, X., & Zou, J. (2019) · PLoS ONE · doi:10.1371/journal.pone.0221756 · Cited by 30
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Li, B., Yang, G., Wu, Y., Chen, J., Xu, H. H. K., Yang, M., Li, M., Ren, B., Feng, M., Weir, M. D., et al. (2017) · Molecules · doi:10.3390/molecules22112013 · Cited by 28
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Self-citationZhang, F., He, S., Jin, J., Dong, G., & Wu, H. (2015) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2015.00055 · Cited by 26
Moussa, D. G., & Aparicio, C. (2020) · PLoS ONE · doi:10.1371/journal.pone.0235283 · Cited by 26
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Self-citationKondo, T., Okawa, H., Hokugo, A., Shokeen, B., Sundberg, O., Zheng, Y., McKenna, C. E., Lux, R., & Nishimura, I. (2022) · Communications Biology · doi:10.1038/s42003-022-03896-7 · Cited by 23
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Davis, I. J., Bull, C., Horsfall, A., Morley, I., & Harris, S. J. (2014) · BMC Microbiology · doi:10.1186/1471-2180-14-196 · Cited by 20
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Self-citationCao, P., Zhang, Y., Dong, G., Wu, H., Yang, Y., & Liu, Y. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.937039 · Cited by 18
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Huang, Y., Li, H., Zhu, C. G., Zhou, X., Wang, H., Han, Q., Ren, B., & Cheng, L. (2021) · Journal of Dentistry · doi:10.1016/j.jdent.2021.103767 · Cited by 16
Saavedra, F. M., Pelepenko, L. E., Boyle, W. S., Zhang, A., Staley, C. M., Herzberg, M. C., Marciano, M. A., & Lima, B. P. (2022) · International Endodontic Journal · doi:10.1111/iej.13742 · Cited by 16
Liu, J., Spencer, N., Utter, D. R., Grossman, A. S., Lei, L., dos Santos, N. C. C., Shi, W., Baker, J. L., Hastürk, H., He, X., et al. (2024) · Microbiome · doi:10.1186/s40168-024-01854-5 · Cited by 21
Self-citationKreth, J., & Merritt, J. L. (2022) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuac052 · Cited by 15
Zhao, H., Wang, X., Liu, Z., Wang, Y., Zou, L., Chen, Y., & Han, Q. (2023) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2023.1116021 · Cited by 15
Sikdar, R., Beauclaire, M. V., Herzberg, M. C., Lima, B. P., & Elias, M. H. (2025) · npj Biofilms and Microbiomes · doi:10.1038/s41522-025-00846-z · Cited by 17
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Self-citationZhou, W., Liang, J., Huang, X., Weir, M., Masri, R., Oates, T., Xu, H. H. K., & Cheng, L. (2023) · Dental Materials · doi:10.1016/j.dental.2023.11.011 · Cited by 14
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Metadata
- Authors
- Tian, Y., He, X., Torralba, M., Yooseph, S., Nelson, K. E., Lux, R., McLean, J. S., Yu, G., & Shi, W.
- Affiliations
- Peking University (CN)
- University of California, Los Angeles (US)
- J. Craig Venter Institute (US)
- Corresponding author
- Yu, G.
- Shi, W.
- Venue
- Molecular Oral Microbiology
- Publisher
- Wiley
- Published
- 2010-09-02
- Volume
- 25
- Issue
- 5
- Pages
- 357-367
- ISSN
- 2041-1006 (ISSN-L)
- PMC
- PMC2951289
- OpenAlex
- W1533894881
- Cited by
- 133
- References
- 44
- Citations by year
- 2026: 9 · 2025: 14 · 2024: 14 · 2023: 7 · 2022: 12 · 2021: 10 · 2020: 17 · 2019: 10 · 2018: 7 · 2017: 9 · 2016: 5 · 2015: 6 · 2014: 4 · 2013: 1 · 2012: 2
- FWCI
- 3.34
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Molecular Oral Microbiology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- U.S. Department of Health and Human Services
- National Institutes of Health (5r01de020102-10, n01ai30071-19-0-3)
- National Institute of General Medical Sciences (GM54666, R01GM054666)
- National Institute of Allergy and Infectious Diseases (N01 AI30071)
- National Institute of Dental and Craniofacial Research (R01-DE020102, DE020102)
- Topics
- Health Sciences › Dentistry › Periodontics › Oral microbiology and periodontitis research
- Physical Sciences › Environmental Science › Ecology › Microbial Community Ecology and Physiology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bacterial biofilms and quorum sensing
- Keywords
- oral microbiota, media development, culture-based methods, oral bacterial diversity, dental caries, periodontal disease
- MeSH terms
- Adult, Culture Media, DNA, Bacterial, Humans, Image Processing, Computer-Assisted, Mouth, Saliva, Sequence Analysis, DNA, Biofilms, Biomass, Microscopy, Confocal, Denaturing Gradient Gel Electrophoresis, Microbial Consortia
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